• 한국정보통신학회논문지
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• 제23권10호
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• pp.1298-1304
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• 2019

9.11 테러 이후 미국을 비롯한 선진국들의 해운물류 안전 보안체계가 크게 강화되었다. 해운물류의 검색에는 강력한 방사선을 투과하여 컨테이너의 내부를 확인하는 컨테이너 검색기 시스템을 주로 사용하는데, 국내에서는 전량 도입품을 적용하여 운용 중이며 국산화 개발에 대한 요구가 증가하고 있다. 이에 본 논문에서는 컨테이너 검색기 시스템의 핵심 구성요소인 X-Ray 어레이 검출 모듈 신호처리 시스템을 개발하여 제안한다. 아날로그 및 디지털 신호처리부를 통합형 하드웨어로 제작하였으며, X-선 데이터의 실시간 수집과 분석을 위해 FPGA 로직과 소프트웨어를 구현하여 시험하였다. 구현된 시스템은 기존 항만에서 사용되는 도입품 대비 해상도와 소비전력 면에서 우세하다.

• 한국안전학회지
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• 제37권2호
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• pp.35-42
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• 2022

When an accident occurs, the associated human activity is typically regarded as a "human error," or a temporal deviation. On the other hand, if the accident results in a serious loss or if it evokes a social issue, the person determined to be responsible may be punished with a "violation" of related laws or regulations. However, as Heinrich stated, it is neither appropriate nor reasonable in terms of probability theory and cognitive science to distinguish whether it is a "human error" or a "violation" with a criterion of resultant accident severity. Nonetheless, some in society get on the social climate to strengthen regulations on workers who have caused accidents, especially violations. This response can present a social issue due to the lack of systematic judgment procedure which distinguishes violations from human errors. The purpose of this study was to develop an objective and systematic procedure to assess whether workers' activities which induced industrial accidents should be categorized as violations rather than human errors. Various analysis techniques for the determination of violation procedure were investigated and compared using an analysis approach method. An appropriate technique was not found, however, for judging the culpability of intentional violations. As an alternative, this study developed the process of creating violations, based on cognitive procedure, as well as the criteria to determine and categorize an activity as a violation. In addition, the developed procedure was applied to cases of industrial accidents and nuclear power plant issues to test its practical applicability. The study demonstrated that the proposed model could be used to determine the existence of a violation even in the case of multiple workers who work simultaneously.

• Molecules and Cells
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• 제44권7호
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• pp.458-467
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• 2021

GPR43 (also known as FFAR2 or FFA2) is a G-protein-coupled receptor primarily expressed in immune cells, enteroendocrine cells and adipocytes that recognizes short-chain fatty acids, such as acetate, propionate, and butyrate, likely to be implicated in innate immunity and host energy homeostasis. Activated GPR43 suppresses the cAMP level and induces Ca²⁺ flux via coupling to Gα_i and Gα_q families, respectively. Additionally, GPR43 is reported to facilitate phosphorylation of ERK through G-protein-dependent pathways and interacts with β-arrestin 2 to inhibit NF-κB signaling. However, other G-protein-dependent and independent signaling pathways involving GPR43 remain to be established. Here, we have demonstrated that GPR43 augments Rho GTPase signaling. Acetate and a synthetic agonist effectively activated RhoA and stabilized YAP/TAZ transcriptional coactivators through interactions of GPR43 with Gα_q/11 and Gα_12/13. Acetate-induced nuclear accumulation of YAP was blocked by a GPR43-specific inverse agonist. The target genes induced by YAP/TAZ were further regulated by GPR43. Moreover, in THP-1-derived M1-like macrophage cells, the Rho-YAP/TAZ pathway was activated by acetate and a synthetic agonist. Our collective findings suggest that GPR43 acts as a mediator of the Rho-YAP/TAZ pathway.

• 자원환경지질
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• 제55권3호
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• pp.273-280
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• 2022

본 연구의 목적은 빅데이터 분석을 활용한 지질자원기술에 대한 사회적 인식을 바탕으로 지질자원기술에 대한 국민 인식 제고 방안을 논의하는 데 있다. 이를 위하여 2010년 1월 1일부터 2022년 4월 14일까지 54개 언론사를 대상으로 언론 기사 제목과 본문에 '지질자원기술'이 포함된 5,044건의 기사를 분석대상으로 삼았으며, 빅데이터 분석을 연구방법으로 채택하였다. 분석 결과, 연구소 중심, 미국·중국·일본 중심, 포항시 지진, 연구원 원장 중심으로 주제어가 구성되어 있었으며, 중요 주제어는 지질, 산업, 광물개발, 환경, 에너지, 원자력, 지하수 등으로 나타났다. 또한, 토픽 분석 결과, 토픽들은 개별적으로 위치하지 않고 전문가, 환경, 연구소 등을 중심으로 상호 연계되어 있고, 미래, 산업, 글로벌 토픽 등으로 확인되었다. 이러한 결과를 바탕으로 지질자원기술의 국민 인식 제고 방안을 논의하였다.

• Tribology and Lubricants
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• 제38권3호
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• pp.73-83
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• 2022

This paper is concerned with an analysis of a surface edge crack emanated from a sharp contact edge. For a geometrical model, a square wedge is in contact with a half plane whose materials are identical, and a surface perpendicular crack initiated from the contact edge exists in the half plane. To analyze this crack problem, it is necessary to evaluate the stress field on the crack line which are induced by the contact tractions and pseudo-dislocations that simulate the crack, using the Bueckner principle. In this Part I, the stress filed in the half plane due to the contact is re-summarized using an asymptotic analysis method, which has been published before by the author. Further focus is given to the stress field in the half plane due to a pseudo-edge dislocation, which will provide a stress solution due to a crack (i.e. a continuous distribution of edge dislocations) later, using the Burgers vector. Essential result of the present work is the corrective functions which modify the stress field of an infinite domain to apply for the present one which has free surfaces, and thus the infiniteness is no longer preserved. Numerical methods and coordinate normalization are used, which was developed for an edge crack problem, using the Gauss-Jacobi integration formula. The convergence of the corrective functions are investigated here. Features of the corrective functions and their application to a crack problem will be given in Part II.

• Tribology and Lubricants
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• 제38권3호
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• pp.84-92
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• 2022

In Part I, developed was a method to obtain the stress field due to an edge dislocation that locates in an elastic half plane beneath the contact edge of an elastically similar square wedge. Essential result was the corrective functions which incorporate a traction free condition of the free surfaces. In the sequel to Part I, features of the corrective functions, F_kij,(k = x, y;i,j = x,y) are investigated in this Part II at first. It is found that F_xxx(ŷ) = F_xyx(ŷ) where ŷ = y/η and η being the location of an edge dislocation on the y axis. When compared with the corrective functions derived for the case of an edge dislocation at x = ξ, analogy is found when the indices of y and x are exchanged with each other as can be readily expected. The corrective functions are curve fitted by using the scatter data generated using a numerical technique. The algebraic form for the curve fitting is designed as F_kij(ŷ) = $\frac{1}{\hat{y}^{1-{\lambda}}I+yp}$$\sum_{q=0}^{m}{\left}$$\left[A_q\left(\frac{\hat{y}}{1+\hat{y}} \right)^q \right]$ where λ_I=0.5445, the eigenvalue of the adhesive complete contact problem introduced in Part I. To investigate the exponent of F_kij, i.e.(1 - λ_I) and p, Log|F_kij|(ŷ)-Log|(ŷ)| is plotted and investigated. All the coefficients and powers in the algebraic form of the corrective functions are obtained using Mathematica. Method of analyzing a surface perpendicular crack emanated from the complete contact edge is explained as an application of the curve-fitted corrective functions.

• 한국분말재료학회지
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• 제29권1호
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• pp.22-27
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• 2022

Conventionally, metal materials are produced by subtractive manufacturing followed by melting. However, there has been an increasing interest in additive manufacturing, especially metal 3D printing technology, which is relatively inexpensive because of the absence of complicated processing steps. In this study, we focus on the effect of varying powder size on the synthesis quality, and suggest optimum process conditions for the preparation of AlCrFeNi high-entropy alloy powder. The SEM image of the as-fabricated specimens show countless, fine, as-synthesized powders. Furthermore, we have examined the phase and microstructure before and after 3D printing, and found that there are no noticeable changes in the phase or microstructure. However, it was determined that the larger the powder size, the better the Vickers hardness of the material. This study sheds light on the optimization of process conditions in the metal 3D printing field.

• Wind and Structures
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• 제34권5호
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• pp.395-405
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• 2022

Tornado-induced damages to high-rise buildings and low-rise buildings are quite different in nature. Tornado losses to high-rise buildings are generally associated with building envelope failures while tornado-induced damages to low-rise buildings are usually associated with structural or large component failures such as complete collapses, or roofs being torn off. While studies of tornado-induced structural damages tend to focus mainly on low-rise residential buildings, transmission towers, or nuclear power plants, the current rapid expansion of city centers and development of large-scale building complexes increases the risk of tornadoes impacting tall buildings. It is, therefore, important to determine how tornado-induced load affects tall buildings compared with those based on synoptic boundary layer winds. The present study applies an experimentally simulated tornado wind field to the Commonwealth Advisory Aeronautical Research Council (CAARC) building and estimates and compares its pressure coefficient effects against the Atmospheric Boundary Layer (ABL) flow field. Simulations are performed at the Wind Engineering, Energy and Environment (WindEEE) Dome which is capable of generating both ABL and tornadic winds. A model of the CAARC building at a scale of 1:200 for both ABL and tornado flows was built and equipped with pressure taps. Mean and peak surface pressures for TLV flow are reported and compared with the ABL induced wind for different time-averaging. By following a compatible definition of the pressure coefficients for TLV and ABL fields, the resulting TLV pressure field presents a similar trend to the ABL case. Also, the results show that, for the high-rise building model, the mean and 3-sec peak pressures are larger for the ABL case compared to the TLV case. These results provide a way forward for the code implementation of tornado-induced pressures on high-rise buildings.

• Journal of Veterinary Science
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• 제23권5호
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• pp.72.1-72.14
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• 2022

Background: The treatment of acute kidney injury (AKI), a common disease in dogs, is limited. Therefore, an effective method to prevent AKI in veterinary clinics is particularly crucial. Objectives: Hydrogen sulfide (H₂S) is the third gaseous signal molecule involved in various physiological functions of the body. The present study investigated the effect of H₂S on cisplatin-induced AKI and the involved mechanisms in dogs. Methods: Cisplatin-injected dogs developed AKI symptoms as indicated by renal dysfunction and pathological changes. In the H₂S-treated group, 50 mM sodium hydrosulfide (NaHS) solution was injected at 1 mg/kg/h for 30 min before cisplatin injection. After 72 h, tissue and blood samples were collected immediately. We performed biochemical tests, optical microscopy studies, analysis with test kits, quantitative reverse-transcription polymerase chain reaction, and western blot analysis. Results: The study results demonstrated that cisplatin injection increased necroptosis and regulated the corresponding protein expression of receptor interacting protein kinase (RIPK) 1, RIPK3, and poly ADP-ribose polymerase 1; furthermore, it activated the expressions of inflammatory factors, including tumor necrosis factor-alpha, nuclear factor kappa B, and interleukin-1β, in canine kidney tissues. Moreover, cisplatin triggered oxidative stress and affected energy metabolism. Conversely, an injection of NaHS solution considerably reduced the aforementioned changes. Conclusions: In conclusion, H₂S protects the kidney from cisplatin-induced AKI through the mitigation of necroptosis and inflammation. These findings provide new and valuable clues for the treatment of canine AKI and are of great significance for AKI prevention in veterinary clinics.

• 한국해안·해양공학회논문집
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• 제34권6호
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• pp.211-221
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• 2022

파의 처오름높이는 제방, 호안 및 방파제와 같은 해안 구조물의 설계에 영향을 미치는 가장 중요한 매개변수 중 하나이다. 본 연구에서는 비정수압 수치모형인 SWASH(Zijlema et al., 2011)를 이용해 고정된 수중 및 부유식 사각형 구조물에 의한 고립파의 처오름높이 저감 효과를 분석하였다. SWASH 수치모형이 고립파의 전파, 쇄파 및 처오름현상을 매우 잘 재현하는 것을 확인하였다. 또한 수중 및 부유식 사각형 구조물에 의한 고립파의 파랑변형을 잘 재현하는 것을 확인하였다. 마지막으로 수중 및 부유식 사각형 구조물의 처오름높이 저감 효과를 검토하였다. 부유식 구조물의 에너지 감쇠효과는 수중 구조물보다 크고, 처오름높이 저감에 더 효과적인 것으로 나타났다.