• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.27 no.4
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• pp.238-243
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• 2014

This paper dealt with the measurement and analysis of partial discharge (PD) under high voltage direct current (HVDC) in SF6 gas. Electrode systems such as a protrusion on conductor (POC), a protrusion on enclosure (POE), a crack on epoxy plate and a free particle (FP) were fabricated to simulate the insulation defects. The analysis system was designed with a Time-Frequency (T-F) map algorithm programed based on LabVIEW. This can arrange the acquired PD pulses into frequency and time domain. A HVDC power source is composed of a transformer (220 V/50 kV), a diode (100 kV) and a capacitor (50 kV, 0.5 ${\mu}F$). The gap between the electrodes is 3 mm, and the $SF_6$ gas was set at 5 bar. PD pulses were detected by a 50 ${\Omega}$ non-inductive resistor. In the analysis, PD pulses were distributed below 0.5 MHz and 20 ns ~ 35 ns for the POC, 0.7 MHz ~ 1.7 MHz, below 0.6 MHz and 10 ns ~ 40 ns and 60 ns ~125 ns for the POE, below 0.1 MHz and 135 ns ~ 215 ns for the crack, and below 1.6 MHz and 250 ns for the FP.

• The Journal of Pediatrics of Korean Medicine
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• v.29 no.1
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• pp.60-68
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• 2015

Objectives The purpose of this study is to establish relationship between functional gastrointestinal disorders in children and Temperament and Character using objective criteria and questionnaires. Methods This study surveyed 3-6 years old 130 children who were attending the kindergarten or daycare center in the vicinity of Gangdong from May 15th, 2014 to November 30th, 2014. The Korean-translated Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III (QPGS-Rome III) and The Junior Temperament and Character Inventory 3-6 (JTCI 3-6) questionnaires were used. Results 1. Between the groups, functional gastrointestinal disorder group scored significantly higher on NS, NS1, NS4, HA4, ST and ST1. 2. As the number of functional gastrointestinal disorders increase, the group scored higher on NS, NS1, NS4, HA4, ST and ST1. Conclusions This study showed functional gastrointestinal disorder group exhibited higher NS, NS1, NS4, HA4, ST and ST1 scores.

• The Journal of Korean Society of Virology
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• v.27 no.2
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• pp.197-207
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• 1997

To investigate the NS4 region of JEV, NS4 cDNA of K94P05 (JEV strain isolated from Korea in 1994) was amplified by RT-PCR and analyzed by sequencing PCR product. Genomic size of NS4 was 1212bp and nucleotide sequence was compared with that of other JEV strains. Nucleotide homology between JaOAr582 and K94P05 was 91.1% and that between Beijing and K94P05 was 89.8%, respectively. But the nucleotide sequence of E region of JaOAr582 and K94P05 showed 97.0% homology and that of Beijing and K94P05 did 95.8% homology. NS4 protein was expressed as a form of fusion protein by a prokaryotic expression system. The induced fusion product showed a lower molecular weight than predicted size and remained insoluble. The NS4 protein might be cleavaged by E. coli protease. Concluding above results, high hydrophobicity of the NS4 protein supported the fact that this protein played a role as a membrane component and the poor nucleotide sequence conservativity among JEV strains suggested that this region might be important to adapt each viral growth environment.

• Korean Journal of Organic Agriculture
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• v.20 no.3
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• pp.385-397
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• 2012

A pot experiment was carried out to examined the effect of electrolyzed micronutrients (Fe, Mn, Zn, Sr, Se, Sn, Co, Ti, and V) solution treatments with nutrient solution and SCB slurry on the mineral content and growth of tomato in cherry tomato (Lycopersicon esculentum). The treatment of nutrient solution (NS)+micronutrients solution (MS) significantly increased the concentrations of Li, Zn, Sr, Se, Ti as compared with that of NS alone in the cherry tomato fruits, and SCB+MS solution treatment significantly increased Li, Zn, Se, Co, Sr, and Ti contents as compared with SCB treatment. The micronutrient contents of MN+SCB+MS treatment were significantly higher in Li, Zn, Se, Co and in Ti than those of SCB and NS treatment, respectively. The growth and yield of cherry tomato fruits was highest with NS treatment. The yield indices of cherry tomato treated with NS+MS treatment and SCB+NS+MS were 97% and 94% of NS treatment. In conclusion, it seems to be possible to produce micronutrient-fortified cherry tomato by the mixed treatment of electrolyzed micronutrients.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.8
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• pp.1150-1159
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• 2018

Objective: Non-synonymous single nucleotide polymorphisms (nsSNPs) were identified in Berkshire selective sweep regions and then were investigated to discover genetic nsSNP mechanisms that were potentially associated with Berkshire domestication and meat quality. We further used bioinformatics tools to predict damaging amino-acid substitutions in Berkshire-related nsSNPs. Methods: nsSNPs were examined in whole genome resequencing data of 110 pigs, including 14 Berkshire pigs, generated using the Illumina Hiseq2000 platform to identify variations that might affect meat quality in Berkshire pigs. Results: Total 65,550 nsSNPs were identified in the mapped regions; among these, 319 were found in Berkshire selective-sweep regions reported in a previous study. Genes encompassing these nsSNPs were involved in lipid metabolism, intramuscular fatty-acid deposition, and muscle development. The effects of amino acid change by nsSNPs on protein functions were predicted using sorting intolerant from tolerant and polymorphism phenotyping V2 to reveal their potential roles in biological processes that may correlate with the unique Berkshire meat-quality traits. Conclusion: Our nsSNP findings confirmed the history of Berkshire pigs and illustrated the effects of domestication on generic-variation patterns. Our novel findings, which are generally consistent with those of previous studies, facilitated a better understanding of Berkshire domestication. In summary, we extensively investigated the relationship between genomic composition and phenotypic traits by scanning for nsSNPs in large-scale whole-genome sequencing data.

• Korean Journal of Microbiology
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• v.54 no.1
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• pp.1-8
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• 2018

A prokaryotic cell has various histone-like proteins also known as nucleoid-associated proteins (NAPs). These proteins bind AT-rich sequence at DNA, which induce DNA wrapping, bending, and bridging, and subsequently regulate the gene expression in bacteria. Because NAPs function in transcriptional silencing of virulence genes, it is important to study their roles in gene silencing and specific mechanisms of these proteins. In this review, we discussed two well-known NAPs, H-NS, and HU, and summarized their roles for gene expression in Escherichia coli and Salmonella Typhimurium. Through the oligomerization and filamentation of H-NS, it represses the expression of virulence genes in human pathogenic bacteria, such as Salmonella Typhimurium, and it works with other NAPs positively or negatively. Recently, H-NS also regulates typhoid toxin expression, which causes typhoid fever and systemic disease in human. Additionally, HU regulates the expression of genes related to both virulence and physiology of Salmonella. Therefore, we suggest that NAPs like H-NS and HU are crucial factors to reveal the molecular mechanisms of virulence gene expression in bacteria.

• Journal of the Korea Society for Simulation
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• v.25 no.4
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• pp.43-52
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• 2016

Wireless sensor network (WSN) technology has been implemented using commercial off-the-shelf microcontrollers (MCUs), In this paper, we propose a simulation environment to realize the physical evaluation of FPGA-based node by considering vertically cross-layered WSN in terms of physical node device and network interconnection perspective. The proposed simulation framework emulates the physical FPGA-based sensor nodes to interoperate with the NS3 through the runtime infrastructure (RTI). For the emulation and interoperation of FPGA-based nodes, we extend a vendor-providing FPGA design tool from the host computer and a script to execute the interoperation procedures. The standalone NS-3 is also revised to perform interoperation through the RTI. To resolve the different time-advance mechanisms between the FPGA emulation and event-driven NS3 simulation, the pre-simulation technique is applied to the proposed environment. The proposed environment is applied to IEEE 802.15.4-based low-rate, wireless personal area network communication.

• Journal of Sasang Constitutional Medicine
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• v.31 no.3
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• pp.34-47
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• 2019

Introduction Cloninger's Novelty-Seeking (NS) and Harm-Avoidance (HA) were found to be the biopsychological characteristic of Sasang typology, and the So-Yang type has high NS and low HA however the So-Eum type as contrary. The purpose of this study was to show the clinical usefulness of these measures as objective clinical index of Sasang typology in foreign countries lacking validated measures. Methods The Sasang type of 103 university students was diagnosed using Questionnaire for Sasang Constitution Classification (QSCC) II and clinical specialist, and biopsychological and physical features with NS, HA, Sasang Personality Questionnaire (SPQ) and BMI. These measures were normalized to make a noble index of 'NS(100-HA)', and the correlation among these were examined with Pearson's correlation. The differences of biopsychological and physical features between Sasang type groups were attested with ANCOVA, and the comparison of clinical usefulness of SPQ and NS(100-HA) were examined with discriminant analysis. Results SPQ and BMI were clinically useful for Sasang typology as shown in previous studies, and the substitution of SPQ with normalized NS(100-HA) was found acceptable. The NS(100-HA) is significantly correlated with SPQ (r=0.466, p<0.01), however not with BMI (r=0.079, ns). The SPQ and NS(100-HA) scores were found to be distinctive between Sasang type groups, and these were found to predict Sasang type of participants with similar correctness. Discussion and Conclusion The current study reviewed the theoretical backgrounds and confirmed the clinical usefulness of Cloninger's biopsychological theory in Sasang typology. These might provide foundations for integrative medicine and cross-cultural biopsychology of the East and West.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.15 no.7
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• pp.1471-1478
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• 2011

A typical standard of vehicular ad hoc networks, WAVE which consists of IEEE 1609.x Family standards and IEEE 802.11p standard, includes the multi-channel coordination and channel synchronization function to provide safety services or public services during a car is driven. Generally, the performance of data communication and networking technologies is evaluated by using simulation tools, such as ns-2, OPNET, OPNET++, etc. However, these tools doesn't provide the operations of WAVE protocol. Therefore, in this paper, we implement and verify WAVE simulation program based on ns-2.

• Korean Journal of Oriental Medicine
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• v.14 no.1
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• pp.145-160
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• 2008

Nelumbinis Semen(NS) has been used in traditional medicine to treat diseases such as depression and diarrhea. In inflammatory responses, microglia produces molecules which are known to play roles in the central nervous system. And we previously studied NS inhibited nitric oxide synthase and secretion of tumor necrosis factor alpha. To explore the global gene expression profiles in BV-2 microglial cell line treated with NS, microarray analysis was performed. The cells were treated with LPS or NS plus LPS for 30min, Ih, 3h, and 6h, respectively. Of 45,101 known genes, with cutoff value of 3-fold change in the expression, 340, 644, 280 and 219 genes were upregulated and 503, 570, 694 and 484 were downregulated in NS treated cells at each time point. The results of the present study shows that treatment of NS reversed the LPS-induced upregulation of such genes as Ecoxsackievirus and adenovirus receptor(CAR), pellino 1, and S100P binding protein. It is thought that microarrays will play an ever-growing role in the advance of our understanding of the pharmacologic actions NS.