• The Korean Journal of Physiology and Pharmacology
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• v.25 no.2
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• pp.159-166
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• 2021

Nicotinamide adenine dinucleotide phosphate oxidases (NOXs) are the major enzymatic source of reactive oxygen species (ROS). NOX2 and NOX4 are expressed in the heart but its role in hypoxia-induced atrial natriuretic peptide (ANP) secretion is unclear. This study investigated the effect of NOX on ANP secretion induced by hypoxia in isolated beating rat atria. The results showed that hypoxia significantly upregulated NOX4 but not NOX2 expression, which was completely abolished by endothelin-1 (ET-1) type A and B receptor antagonists BQ123 (0.3 μM) and BQ788 (0.3 μM). ET-1-upregulated NOX4 expression was also blocked by antagonists of secreted phospholipase A2 (sPLA2; varespladib, 5.0 μM) and cytosolic PLA2 (cPLA2; CAY10650, 120.0 nM), and ET-1-induced cPLA2 expression was inhibited by varespladib under normoxia. Moreover, hypoxia-increased ANP secretion was evidently attenuated by the NOX4 antagonist GLX351322 (35.0 μM) and inhibitor of ROS N-Acetyl-D-cysteine (NAC, 15.0 mM), and hypoxia-increased production of ROS was blocked by GLX351322. In addition, hypoxia markedly upregulated Src expression, which was blocked by ET receptors, NOX4, and ROS antagonists. ET-1-increased Src expression was also inhibited by NAC under normoxia. Furthermore, hypoxia-activated extracellular signal-regulated kinase 1/2 (ERK1/2) and protein kinase B (Akt) were completely abolished by Src inhibitor 1 (1.0 μM), and hypoxia-increased GATA4 was inhibited by the ERK1/2 and Akt antagonists PD98059 (10.0 μM) and LY294002 (10.0 μM), respectively. However, hypoxia-induced ANP secretion was substantially inhibited by Src inhibitor. These results indicate that NOX4/Src modulated by ET-1 regulates ANP secretion by activating ERK1/2 and Akt/GATA4 signaling in isolated beating rat hypoxic atria.

• Transactions of the Korean Society of Automotive Engineers
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• v.13 no.5
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• pp.181-187
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• 2005

The behavior of fox adsorption and desorption of the NOx storage catalyst supported on Ba additive were studied by the TPA/TPD experiments and reactivity tests. Applying the transient responses and NOx TPA/TPD test by CLD were effective methods to analyze the characteristics of the NOx storage catalyst. NOx variation of the NOx storage catalyst in the lean air/fuel conditions according to temperature was dominated by NOx adsorption and desorption rather than catalytic reduction. The presence of reductants in the lean mixture promoted the NOx desorption at the $500^{\circ}C$ higher temperature. The temperatures for maximum NOx conversion with CH4 and $C_3H_6$ as a rich spike reductant appear around $500^{\circ}C\;and\; 400^{\circ}C$ respectively.

• Clean Technology
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• v.14 no.2
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• pp.117-122
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• 2008

Theoretical analysis was conducted on the combustion and the NOx formation characteristics of the coal-derived synthetic gases with medium-BTU heating value. The synthetic gas was assumed to contain the major species of CO, $H_2,\;CO_2$, and $N_2$ and the minor species of $CH_4$ and $NH_3$. Through thermochemical analysis on the combustion of the synthetic gas, the flame temperature, major and minor species of exhaust gas, and thermal and fuel NOx emissions were computed. In addition, the effects of the $CH_4$ and the $NH_3$ components in syngas fuel on combustion and NOx emission were investigated. Based on the computed results on the synthetic gases, basic direction and guidelines were provided fur the low NOx design of gas turbine combustor.

• Proceedings of the Korea Society for Energy Engineering kosee Conference
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• 2002.11a
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• pp.155-160
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• 2002

연소시 발생하는 오염물질 중 NOx는 심각한 대기오염의 원인이 되는 것으로 알려져 있어, 각종 연소기 등에서 발생하는 NOx 저감을 위한 연구가 중요하게 대두되었다. 특히 확산화염은 예혼합화염 및 부분예혼합화염에 비해 NOx, Soot 등 오염물질이 발생할 가능성은 높으나 화염 안정성이 좋아 산업용 연소기에 많이 이용되고 있어 보다 다양한 NOx 저감 기술의 필요가 요구되고 있다.(중략)

• Journal of Environmental Science International
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• v.16 no.1
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• pp.1-8
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• 2007

Atmospheric photochemistry of $O_3-NOx-RH$ were considered theoretically, to clarify the reasons for the different trends of between the formation of photochemical oxidants (Ox) and its primary pollutants for the Low-and High-NOx regimes. Equations of OH, $HO_2$, and production of ozone ($O_3$) as a function of nitrogen oxides (NOx) and reactive hydrocarbons (RH) were represented in this study. For the Low-NOx regime, $HO_2$ radical is proportional to RH but independent of NOx. OH radical is proportional to NOx but inversely-proportional to RH. $O_3$ production is proportional to NOx but has a weak dependence on RH. For the High-NOx regime, OH and $HO_2$ radicals concentrations and $O_3$ production are proportional to RH but inversely-proportional to NOx. In addition, the Osaka Bay and surrounding areas of Japan were evaluated with the mass balance of odd-hydrogen radicals (Odd-H) using CBM-IV photochemical mechanism, in order to distinguish the Low- and High-NOx regimes. The Harima area (emission ratio, RH/NOx = 6.1) was classified to the Low-NOx regime. The Hanshin area (RH/NOx = 3.5) and Osaka area (RH/NOx = 4.3) were classified to the High-NOx regime.

• Journal of Advanced Marine Engineering and Technology
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• v.27 no.3
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• pp.373-380
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• 2003

According to the NOx regulations of annex Vi to IMO MARPOL 73/78, all diesel engines with a power output of more than 130 kW should be delivered so as to comply with the IMO speed dependent NOx limit. It is inevitable to adopt this regulations for marine engines Therefore, most of diesel engines which are being currently built should be designed and tested in accordance with the NOx technical code In this study, NOx concentrations of 4 type engines were measured with portable NOx measuring system recommended by ISO-8178. As the results NOx concentrations of each engine by variation of engine speed and engine load were visualized Also these results can be utilized for the basic design and development of diesel engine for NOx reduction.

• 한국연소학회:학술대회논문집
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• 2001.06a
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• pp.147-155
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• 2001

The NOx emission characteristics of jet flames fueled with $H_2$ and $CH_4$ were studied. Experimental and numerical investigations were carried out for various flames with varying equivalence ratio, fuel flow rate and nozzle diameter. The Emission indices of NOx(EINOx) were measured by chemiluminescent method and calculated by simulation using detailed chemistry. The results show that EINOx of $CH_4$ and $H_2$ flames have different trends in terms of equivalence ratio and fuel flow rate but have the same trends in terms of nozzle diameter. These differences can be explained by the following Thermal and Prompt trends in both flames. Thermal EINOx trends can be describe in function of residence time in the high-temperature region weighted by the maximum flame temperature and Prompt EINOx trends can be described in function of flame surface area of each combustion conditions.

• Journal of the Korean Society of Combustion
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• v.6 no.1
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• pp.36-43
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• 2001

The NOx emission characteristics of jet flames fueled with $H_2\;and\;CH_4$ were studied. Experimental and numerical investigations were carried out for various flames with varying equivalence ratio, fuel flow rate and nozzle diameter. The Emission indices of NOx(EINOx) were measured by chemiluminescent method and calculated by numerical model based on detailed chemistry. The results show that EINOx of $CH_4\;and\;H_2$ flames have different trends in terms of equivalence ratio and fuel flow rate but have the same trends in terms of nozzle diameter. These differences can be explained by the following Thermal and Prompt trends in both flames. Thermal EINOx is quite sensitive to the residence time in the high-temperature region weighted by the maximum flame temperature. Prompt EINOx is mainly influenced by flame surface area of each combustion conditions.

• International Journal of Automotive Technology
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• v.8 no.6
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• pp.667-674
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• 2007

Various types of NOx storage catalysts for NGV's were designed, manufactured, and tested in this work on a model gas test bench. As in most of other studies on NOx storage catalyst, alkaline earth metal barium(Ba) was used as the NOx adsorbing substance. The barium-based experimental catalysts were designed to contain different amounts of Ba and precious metals at various ratios. Reaction tests were performed to investigate the NOx storage capacity and the NOx conversion efficiency of the experimental catalysts. From the results, it was found that when Ba loading of a catalyst was increased, the quantity of NOx stored in the catalyst increased in the high temperature range over 350. With more Ba deposition, the NOx conversion efficiency as well as its peak value increased in the high temperature range, but decreased in the low temperature range. The best of de-NOx catalyst tested in this study was catalyst B, which was loaded with 42.8 g/L of Ba in addition to Pt, Pd and Rh in the ratio of 7:7:1. In the low temperature range under $450^{\circ}C$, the NOx conversion efficiencies of the catalysts were lower when $CH_4$, instead of either $C_3H_6$ or $C_3H_8$, was used as the reductant.

• Journal of the Korea Convergence Society
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• v.10 no.4
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• pp.131-138
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• 2019

Diesel engines have important advantages over its gasoline counterpart including high thermal efficiency, high fuel economy and low emissions of CO, HC and $CO_2$. However, NOx reducing is more difficult on diesel engines because of the high $O_2$ concentration in the exhaust, marking general three way catalytic converter ineffective. Two method available technologies for continuous NOx reduction onboard diesel engines are Urea-SCR and LNT. The implementation of the Urea-SCR systems in design engines have made it possible for 2.5l and over engines to meet the tightened NOx emission standard of Euro-6. In this study, we investigate the characteristics of NOx reduction with respect to engine speed, load, types of catalyst and the $NH_3$/NOx ratio and present the conditions which maximize NOx reduction. Also we provide detailed experimental data on Urea-SCR which can be used for the preparation for standards beyond Euro-6.