• Proceedings of the KIEE Conference
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• 2000.07e
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• pp.129-131
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• 2000

The moving vehicle with disturbances has the 6 degree of freedom motion in the pitching, Yawing, and rolling directions of two independent axes. The control system in such a moving vehicle has to perform disturbance rejection. This paper present PID controller with disturbance rejection function, low sensitivity filter and notch filter for bending frequency rejection. The performance of a designed system has been certified by the simulation and experiment and experiment results.

• PNF and Movement
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• v.17 no.2
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• pp.303-310
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• 2019

Purpose: This study aimed to investigate the correlation between abdominal muscle strength and measures of respiratory function in stroke patients. Methods: The study participants comprised 17 (male: 12, female: 5) stroke patients hospitalized at W rehabilitation hospital in Busan, South Korea. Abdominal muscle strength was assessed using a digital manual dynamometer for 5 seconds contacting the sternal notch of the participants to bend the trunk. Respiratory function (forced vital capacity, forced expiratory volume in one second, forced expiratory volume in one second/forced vital capacity, and peak expiratory flow) was assessed using a spirometer. The collected data were analyzed using Pearson's correlation analysis, and the significance level was set 0.05. Results: A statistically significant correlation was found between abdominal muscle strength and forced vital capacity, forced expiratory volume in one second, and peak expiratory flow. However, abdominal muscle strength and forced expiratory volume in one second/forced vital capacity were not significantly correlated. Conclusion: This study demonstrated that there is a relationship between abdominal muscle strength and respiratory function. Exercise programs to strengthen the abdominal muscles are therefore necessary to improve respiratory function in stroke patients.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.14 no.1
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• pp.30-36
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• 2005

This study is to investigate a damage estimation of single edge notched tensile specimens as a function of acoustic emission(AE) according to the uni-directionally oriented carbon fiber/epoxy composites, CFRP In fiber reinforced composite materials, AE signals due to several types of failure mechanisms are typically observed. These are due to fiber breakage, fiber pull-out matrix cracking, delamination, and splitting or fiber bundle breaking. And these are usually discriminated on the basis of amplitude distribution, event counts, and energy related parameters. In this case, AE signals were analyzed and classified 3 regions by AE event counts, energy and amplitude for corresponding applied load. Bath-tub curve shows 3 distinct periods during the lifetime of a single-edge-notch(SEN) specimen. The characterization of AE generated from CFRP during SEN tensile test is becoming an useful tool f3r the prediction of damage failure or/and failure mode analysis.

• Transactions of the Korean Society of Mechanical Engineers
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• v.17 no.10
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• pp.2475-2482
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• 1993

The effects of the hole size(2R) and the specimen width(W) on the fatigue strength and the fatigue life in plain woven glass/epoxy composite plates are experimentally investigated under constant amplitude tensile fatigue loading. It is shown in this study that the notch sensitivity under fatigue loading is lower than that under static loading. It can be explained by the fact that the stress concentration is relaxed by the damage developed at the boundary of circular hole. To predict the fatigue strength at a specific cycle, the modified point stress criterion represented as a function of the geometry of the specimen(2R and W) is applied. It is found that the model used in the prediction of the notched tensile strength predicts the fatigue strength with reasonable accuracy. A model for predicting the fatigue life in the notched specimen, based on the S-$N_f$, curve in the smooth specimen, is suggested.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.3 no.3
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• pp.541-546
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• 1999

The head-related transfer function (HRTF), which expresses the acoustic process from the sound source to the human ears in the free field, contains critical informations which the location of the source can be traced. It also makes it possible to realize multi-dimensional acoustic system that can approximately generate non-existing sound source. The use of non-individual, common HRTF brings performance degradation in localization ability such as front-back judgment error, elevation judgment error. In this paper, we have reduced the error on vertical plane by increasing the spectral notch level. The performance of the proposed method was Proved through subjective test that it is Possible to improve the ability to locate stationary/moving source.

• The Korean Journal of Physiology and Pharmacology
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• v.23 no.4
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• pp.251-261
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• 2019

Allergic asthma, is a common chronic inflammatory disease of the airway presenting with airway hyperresponsiveness and airway remodelling. T helper cells-derived cytokines are critically associated with asthma pathogenesis. Janus kinase-signal transduction and activation of transcription (JAK/STAT) signaling is found to be involved in asthma. Magnolol is a plant-derived bioactive compound with several pharmacological effects. The study aimed to assess the effects of magnolol in ovalbumin (OVA)-induced asthmatic model. BALB/c mice were sensitized and challenged with OVA. Magnolol (12.5, 25, or 50 mg/kg body weight) was administered to separate groups of animals. Dexamethasone was used as the positive control. Cellular infiltration into the bronchoalveolar lavage fluid (BALF) were reduced on magnolol treatment. The levels of Th2 and Th17 cytokines were reduced with noticeably raised levels of interferon gamma. Lung function was improved effectively along with restoration of bronchial tissue architecture. OVA-specific immunoglobulin E levels in serum and BALF were decreased by magnolol. Magnolol reduced Th17 cell population and effectively modulated the JAK-STAT and Notch 1 signaling. The results suggest the promising use of magnolol in therapy for allergic asthma.

• Advances in concrete construction
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• v.1 no.4
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• pp.319-340
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• 2013

This paper presents a comparative study on the double-K fracture parameters of concrete obtained using four existing analytical methods such as Gauss-Chebyshev integral method, simplified Green's function method, weight function method and simplified equivalent cohesive force method. Two specimen geometries: three point bend test and compact tension specimen for sizes 100-500 mm at initial notch length to depth ratios 0.25 and 0.4 are used for the comparative study. The required input parameters for determining the double-K fracture parameters are derived from the developed fictitious crack model. It is found that the cohesive toughness and initial cracking toughness determined using weight function method and simplified equivalent cohesive force method agree well with those obtained using Gauss-Chebyshev integral method whereas these fracture parameters determined using simplified Green's function method deviates more than by 11% and 20% respectively as compared with those obtained using Gauss-Chebyshev integral method. It is also shown that all the fracture parameters related with double-K model are size dependent.

• BMB Reports
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• v.49 no.5
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• pp.255-262
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• 2016

The disease known as cerebral cavernous malformations mostly occurs in the central nervous system, and their typical histological presentations are multiple lumen formation and vascular leakage at the brain capillary level, resulting in disruption of the blood-brain barrier. These abnormalities result in severe neurological symptoms such as seizures, focal neurological deficits and hemorrhagic strokes. CCM research has identified 'loss of function' mutations of three ccm genes responsible for the disease and also complex regulation of multiple signaling pathways including the WNT/β-catenin pathway, TGF-β and Notch signaling by the ccm genes. Although CCM research is a relatively new and small scientific field, as CCM research has the potential to regulate systemic blood vessel permeability and angiogenesis including that of the blood-brain barrier, this field is growing rapidly. In this review, I will provide a brief overview of CCM pathogenesis and function of ccm genes based on recent progress in CCM research.

• Journal of Periodontal and Implant Science
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• v.29 no.3
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• pp.507-519
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• 1999

The ultimate objective of periodontal treatment is to stop disease progression and to regenerate destroyed periodontal tissues and thereby regain normal function. Growth factors are naturally found polypetides which stimulate many cellular activities pertaining to wound healing by acting as signal molecule in controlling cell movement, proliferation, and matrix production. Platelet derived growth factor (PDGF) is 28,000-35,000 Da molecular weight dimeric protein with 2 long positively charged polypeptide chains connected by sulfide bonds. The purpose of this study is to evaluate histologically the initial guided tissue regeneration in a periodontal defect f a beagle dog treated with a biodegradable membrane formed with polylactic acid (poly-L-lactic acid) and polyglycolic acid loaded with 200ng/$cm^2$ platelet derived growth factor. 2 beagle dogs were used in he experiment. $5mm{\times}6mm$ alveolar bone defect was formed in upper and lower canines and third premolars and a reference notch was placed. PDGF-BB non-containing membrane was used as control. Each defect was randomly assigned to the test roup or the control group. The dogs were sacrificed 3 weeks after membrane placement. Toluidine blue and multiple staining was done for histological analysis. In the 3 week specimen in the control group, no new one formation could be seen. Small amount f bone resorption below the notch could be seen. In the notch, loose connective tissue with infiltration of inflammatory cells could be seen. Also thin discontinuous new cementum could be seen and the membrane still retained its structure. Where PDGF-BB containing membrane was used, new bone formation could be seen in the notch at weeks and also continuous thin cementum could be seen. PDL cells were observed between new bone and new cementum and some were attached to bone and cementum. These results suggest that new bone and cementum formation seen when PDGF-BB loaded membrane was used was due to inhibition of downgrowth of epithelial cells and also due to continuous release of the growth factor. Further study on the resorption characteristics of the membrane nd the release characteristics of the PDGF-BB is necessary. Also, development of a membrane easier to use clinically is necessary.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.25 no.9
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• pp.886-894
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• 2014

A wideband bow-tie antenna fed by wideband microstrip-coplanar stripline(CPS) balun and band notch structures that can be applied to bow-tie antenna are proposed in this paper. In order to increase bandwidth, bow-tie radiators are reshaped so that the surface current flows continuously, and wideband impedance matching is achieved by adjusting strip width and spacing of CPS feeding line. The VSWR is measured as 2:1 over the wide frequency range of 2.3~12 GHz. The fabricated antenna size is $60mm{\times}60mm$. In order to achieve the band-notch function at WLAN(5.8 GHz), ${\lambda}/4$ folded-slits located ${\lambda}/4$ away from feeding point are utilized. To minimize the slit size, folded-slit type is adopted. The measured VSWR is 7:1 and gain attenuation is 14 dB at 5.8 GHz.