• 대한한의학원전학회지
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• 제26권1호
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• pp.27-38
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• 2013

Objective : This article shows that while Seishu Hanaoka(華岡靑洲) is known to have developed an effective anesthetic formula composed of traditional herbs and performed the world first partial mastectomy under a general anesthesia in 1804, anesthetic formulas very similar to those developed by him were widely recorded and deemed used in Japan and Northeast Asia before his invention. The origin of the formulas will be tracked down to compare with the several formulas broadly administered in the region. Methods : Historical literature analysis was adopted to achieve the objective. 1. Mayaku-ku (麻藥考): this book is the main medical classic by Nakagawa Syutei(中川修亭) that introduces Seishu Hanaoka, his anesthetic formulas and mastectomy. 2. Northeast medical classics: Seuideukhyobang (世醫得效方) in 1337, Uibangryuchui (醫方類聚), Uihui(宜彙) and so on. Result : Herbs such as aconitum and datura were applied as a anesthetic agent early on before the Chinese Yuan dynasty. In Korea as well, some old medical books documented such use of those herbs and relevant formulas. Conclusion : Formulas that counted as invented and employed by Seishu Hanaoka as anesthetics, in fact, had been widely known and used in the region before his era. We should pay due attention to his creativity that combined a western surgical intervention and traditional anesthetic agents and successfully performed a newly introduced surgical practice in Japan. The point is that Hanaoka took note of anesthetic herbs or formulas traditionally inherited in North-east Asian medicine and successfully applied them to the surgical procedures for breast cancer, or mastectomy and mammotomy. This history alerts us to neglected or forgotten potentials of traditional medicine in anesthetic treatment and more.

• 정보처리학회논문지D
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• 제10D권1호
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• pp.101-108
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• 2003

동북아 중심 항만의 기반을 다지기 위해 자동화항만의 건설이 시급히 요청되고 있다. 따라서 우리나라에 적합한 자동화항만의 운영시스템 레이아웃 설계방안을 제시하고자 한다. 본 논문에서는 자동화항만의 운영시스템이 추구해야말 목표를 충족시키며, 각 자동화 장비를 통한 화물의 수출입 이동경포에 따라 운영시스템의 모델을 4가지로 구분하고 여러 입력 요소들을 변경시켜 가며 시행착오를 거쳐 동적으로 분석해 나감으로서 최적의 운영시스템 모델을 선정하고, 그에 대한 수출입화물별 야드 운영시스템 레이아웃을 설계하였다. 특히 미래의 자동화항만에서는 어떠한 자동화 장비를 사용하느냐에 따라 그 생산성이 달라진다. 그러나 현실적으로 비용측면과 현재의 작업 흐름을 도외시 할 수 없기 때문에 현재의 작업을 최적화하고 현재의 사용 장비와 자동화 장비의 대체로 작업의 혼선이 발생하지 않은 방법을 선택하여 레이아웃을 설계하였다. 본 논문의 야드 운영시스템에서 기술한 장비들은 Q/C(Quay Crane)을 제외한 모든 야드 장비가 완전자동화를 전제로 한 것이다.

• Parasites, Hosts and Diseases
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• 제37권4호
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• pp.265-270
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• 1999

The gene encoding Plasmodium vivax circumsporozoite protein (PvCSP) exhibits polymorphism in many geographical isolates. The present study was designed to investigate polymorphism in PvCSP gene of P. vivax isolates in Korea. Thirty isolates, obtained from indigenous cases in Yonchon-gun, Kyonggi-do in 1997, were subjected for sequencing and RFLP analysis of the repeat and post-repeat regions of PvCSP gene and two genotypes (SK-A and SK-B) were identified. The genotype of 19 isolates was SK-A and that of 11 isolates was SK-B. Although the number of 12-base repeats present in SK-A was three while two were found in a Chinese strain CH-5, the repeat sequence of SK-A was identical to that of CH-5 except for one base substitution. Compared with known data there was no identical isolates with SK-B, but the sequence of SK-B was similar to that of a North Korean (NK) isolate. These results indicate that two genotypes of PvCSP coexist in the present epidemic area of Korea and the present parasite may originate from East Asia. RFLP would be useful to classify genotypes of P. vivax population instead of gene sequencing.

• 패션비즈니스
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• 제1권1호
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• pp.27-42
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• 1997

The Korean fashion industry is composed of originality, technique and business management. It is going to be the main role in the living and cultural industry in 21th century as a strategic advanced industry. On the other hand, more than 15,000 persons who majored in correlated fashion are graduated from universities, colleges, and fashion schools every year. But professional and competent persons specialized in clothings are very insufficient. So cultivation of the talented for fashion industry must be suitablely and differentially carried out, according to regional distinction or characteristics of each university, college level, institute and so on. At same time, it is for the subdivided professional educations in fashion field, also. Education institutions related fashion have to practice not only theory but also field-oriented education of fashion industry. The fashion enterprise must invest resolutely in reeducations for incoming and reading employees, too. Briefing the program of cultivating the competent as follows : (1) The execution of certification programes based on professional job series. (2) Cultivation of the talent by cooperation of industry and educational field. (3) Upbringing the specialists who have both abilities of foreign language and living cultural profession. (4) Establishment of a base oriented north-east Asia as the central fashion business. (5) Efficient using of multi-media. (6) Innovation of technology. (7) Preferential treatment of skilled labors apparel industry field. (8) Establishment of the Korean Society of Fashion Business for a bridge of industrial-educational complex and government, for cultivation of the talent. The programs of 'cultivation of the talent' must be differed from to whom', 'what', 'how long'. But the commonness in all is to need the stimulative education and creativity. Through it, 'what and how think' and 'how application' to all directions is acquired.

• The Plant Pathology Journal
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• 제36권1호
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• pp.87-97
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• 2020

The development of reverse transcription-polymerase chain reaction using degenerate primers against conserved regions of most potyviral genomes enabled sampling of the potyvirome. However, these assays usually involve sampling potential host plants, but identifying infected plants when they are asymptomatic is challenging, and many plants, especially wild ones, contain inhibitors to DNA amplification. We used an alternative approach which utilized aphid vectors and indicator plants to identify potyviruses capable of infecting common bean (Phaseolus vulgaris). Aphids were collected from a range of asymptomatic leguminous weeds and trees in Iran, and transferred to bean seedlings under controlled conditions. Bean plants were tested serologically for potyvirus infections four-weeks postinoculation. The serological assay and symptomatology together indicated the presence of one potyvirus, and symptomology alone implied the presence of an unidentified virus. The partial genome of the potyvirus, encompassing the complete coat protein gene, was amplified using generic potyvirus primers. Sequence analysis of the amplicon confirmed the presence of an isolate of Wisteria vein mosaic virus (WVMV), a virus species not previously identified from Western Asia. Phylogenetic analyses of available WVMV sequences categorized them into five groups: East Asian-1 to 3, North American and World. The Iranian isolate clustered with those in the World group. Multiple sequence alignment indicated the presence of some genogroup-specific amino acid substitutions among the isolates studied. Chinese isolates were sister groups of other isolates and showed higher nucleotide distances as compared with the others, suggesting a possible Eastern-Asian origin of WVMV, the main region where Wisteria might have originated.

• 한국항만경제학회지
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• 제17권1호
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• pp.27-51
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• 2001

The purpose of this paper is to investigate the productive efficiency of world container ports by using the DEA (Data Envelopment Analysis) method and raw data from previous research in measuring the international competitiveness of world container ports. Ports have to cope with rapid changes in shipping environments. In order for a port to compete in the global market, it must provide port services promptly and accurately. Basically, there are two approaches to measuring the international competitiveness of a container port. First, there is the traditional productivity analysis method, which analyzes productivity based on the container port's facilities (efficiency, selectivity, land availability), and by its general capacity (handling ability, storage capacity, terminal productivity). Second there is multi-attribute utility analysis, which considers several elements including the reasons for selecting particular container ports and factors determining international competitiveness. This paper follows the first method (traditional productivity analysis) and extends the limitation of previous studies by using the DEA method newly, and suggesting: the relative productive efficiency of container ports. The main results of this paper are as follows: First, the results of the DEA analysis in terms of world container ports matches that of a previous study (Jun et al., 1993) at a level of 35%. The low ratio is due to the constrained set of input-output elements, the result of only twenty container ports being analyzed in this paper. Second, the result of the DEA analysis in terms of North-East Asia's container ports matches with that of a previous study (Ha, 1996) at a level of 100 percent. Therefore we can conclude that the DEA analysis is the best measurement method for international competitiveness. Policy implications for this study are as follows: First, when port authorities want to measure the international competition power of container ports and enhance their productive efficiency, they should consider the traditional method and newly introduce the DEA method. Second, according to the analysis results of the DEA method, pen authorities should recommend benchmarking ports as reference ports in order to enhance the productive efficiency of container ports that show an efficiency score of below 1.

• 한국의류학회지
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• 제6권2호
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• pp.1-7
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• 1982

Baik-Eui is the white clothes and Korean typical way of wearing, Baik-Eui was used by the over 80$\~$90 percents of people, which proves that Baik-Eui was the very clothes of common people. Moreover, even King himself in Koryo Dynasty is said to have worn white clothes when he was out of official hours. And wearing Baik-Eui was regarded as polite manners among the noble men in Yi Dynasty in spite of strict prohibitions of wearing it. That fact proves that it was loved by Korean people in general. Baik-Eui can be found its origin from many peoples of North East Asia in ancient time. Some say that wearing Baik-Eui is considered as a kind of worship of the sun, or purity of Korean people. But from the economical point of view, Baik-Eui was primitive in it's color. It means that their clothes were made from original clothes, not dyed. This study on the social reasons affecting to Baik-Eui, they are summarized as follows; 1. This Baik-Eui had been originated from the ancient economical and rigid circumstances of society. Everlasting poverty and diprivation of joy in life of Korean naturally made them have inclination of wearing it 2. Also common people were restricted in their choice of dress color by government. Even rich could not wear a colored clothes except the dyes permitted by them. 3. Socially, People wore white clothes through various kinds of ceremony, among which funeral was the most important. As we had the large family system, and usually the funeral at that time was longer in its period than now. Thus, Korean got accustomed to wear whit clothes more and more.

• Preventive Nutrition and Food Science
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• 제17권2호
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• pp.122-128
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• 2012

Gelidium (G.) elegans is a red alga inhabiting intertidal areas of North East Asia. We examined anti-oxidative and anti-inflammatory effects of G. elegans, depending on drying and extraction conditions, by determining reactive oxygen species (ROS) and nitric oxide (NO) in 3T3-L1 and RAW 264.7 cells. Extraction yields of samples using hot air drying (HD) and far-infrared ray drying (FID) were significantly higher than those using natural air drying (ND). The 70% ethanol extracts showed the highest total phenol and flavonoid contents compared to other extracts (0, 30, and 50% ethanol) under tested drying conditions. The scavenging activity on 2,2-diphenyl- 1-picrylhydrazyl (DPPH) and nitrite correlated with total phenol or flavonoid content in the extracts. The greatest DPPH scavenging effect was observed in 70% ethanol extract from FID and HD conditions. The production of ROS and NO in 3T3-L1 and macrophage cells greatly decreased with the 70% ethanol extraction derived from FID. This study suggests that 70% ethanol extraction of G. elegans dried by FID is the most optimal condition to obtain efficiently antioxidant compounds of G. elegans.

• 당뇨병
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• 제19권3호
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• pp.135-139
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• 2018

The sodium-glucose cotransporter-2 inhibitor (SGLT2i) is a new anti-hyperglycemic agent that have function to concomitantly inhibit the reabsorption of glucose and sodium in the renal proximal convoluting tubule. Recent two cardiovascular outcome trials showed that a lower risk of cardiovascular events with SGLT2i in people with type 2 diabetes. In addition, prior real-world data demonstrated similar SGLT2i effects, but these studies were limited to the United States and Europe. Thus, the CVD-REAL (Comparative Effectiveness of Cardiovascular Outcomes in New Users of Sodium-Glucose Cotransporter-2 Inhibitors) 2 Study was investigated cardiovascular outcomes in those initiated on SGLT2i versus other glucose-lowering drugs (oGLDs) across 6 countries in the Asia Pacific, the Middle East, and North American regions. In Korea, 336,644 episodes of initiation in SGLT2i or oGLD group between September 2014 and December 2016 were identified in Korea National Health Insurance database after propensity score matching. SGLT2i users was associated with a lower risk of all-cause death (hazard ratio [HR], 0.72; 95% confidence interval [CI], 0.67~0.77), hospitalization for heart failure (HHF) (HR, 0.87; 95% CI, 0.82~0.92), all-cause death or HHF (HR, 0.81; 95% CI, 0.78~0.85), myocardial infarction (HR, 0.81; 95% CI, 0.74~0.89), and stroke (HR, 0.82; 95% CI, 0.78~0.86) compared with oGLD users. In conclusion, initiation of SGLT2i had a lower risk of cardiovascular events in people with type 2 diabetes compared with oGLDs.

• 한국항만경제학회지
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• 제23권2호
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• pp.1-24
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• 2007

빠른 경제성장과 교역량의 증가에 힘입어 중국은 이제 세계에서 가장 많은 컨테이너 물동량을 처리한 국가가 되었다. 그리고 컨테이너선의 대형화와 신속화 추세에 발맞추어 동북아 주요항만이 직면하는 환경도 상당히 빠르게 변하고 있다. 상해항은 육지로부터 약 30km 떨어진 대양산과 소양산을 개발하여 2005년 말에 제1기 터미널을 그리고 2006년에 제2기 터미널을 개장하였다. 그리고 2012년까지 전체 29선석을 조성하여 1,500만 TEU를 처리할 예정으로 있다. 컨테이너 처리물량에서 부산항을 추월한 상해항은 2,006년도 연간 물동량을 약 2,170만 TEU를 처리하여 세계 제3위의 지위를 확고히 했으며, 향후 세계 제1위의 컨테이너 처리항만으로 부상할 것으로 보인다. 세계 제5위의 컨테이너 처리항만이고, 동북아 중심항만이 되고자 하는 부산항에 양산항의 개장 및 향후 개발 계획에 따른 주변 상황에 능동적으로 대처하기 위한 다양한 대응전략을 제시해 본다.