• Title/Summary/Keyword: Normal variability

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RAINFALL SEASONALITY AND SAMPLING ERROR VARIATION

  • Yoo, Chul-sang
    • Water Engineering Research
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    • v.2 no.1
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    • pp.63-72
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    • 2001
  • The variation of sampling errors was characterized using the Waymire-Gupta-Rodriguez-Iturbe multi-dimensional rainfall model(WGR model). The parameters used for this study are those derived by Jung et al. (2000) for the Han River Basin using a genetic algorithm technique. The sampling error problems considered are those for using raingauge network, satellite observation and also for both combined. The characterization of sampling errors was done for each month and also for the downstream plain area and the upstream mountain area, separately. As results of the study we conclude: (1) The pattern of sampling errors estimated are obviously different from the seasonal pattern of monthly rainfall amounts. This result may be understood from the fact that the sampling error is estimated not simply by considering the rainfall amounts, but by considering all the mechanisms controlling the rainfall propagation along with its generation and decay. As the major mechanism of moisture source to the Korean Peninsula is obviously different each month, it seems rather normal to provide different pattern of sampling errors from that of monthly rainfall amounts. (2) The sampling errors estimated for the upstream mountain area is about twice higher than those for the down stream plain area. It is believed to be because of the higher variability of rainfall in the upstream mountain arean than in the down stream plain area.

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The development of Fetal Heart Rate monitoring system based on DSP processor (DSP 프로세서를 이용한 태아심음 및 자궁수축감시장치의 개발)

  • Jnag, D.P.;Kim, K.H.;Lee, Y.H.;Lee, Y.K.;Bak, M.I.;Lee, D.S.;Kim, S.I.
    • Proceedings of the KOSOMBE Conference
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    • v.1996 no.05
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    • pp.320-324
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    • 1996
  • Digital fetal monitoring system based on the personal computer combined with the digital signal processing board was implemented. The DSP board acquires and digitally processes ultrasound fetal Doppler signal for digital rectification, FIR filtering, autocorrelation function calculation, its peak detection and MEDIAN filtering. The personal computer interfaced with the DSP board is in charge of graphic display, hardcopy, data transmission and on-line analysis of fetal heart rate change including and variability. I used a recursive technique for autocorrelation function computation method and MEDIAN filter which can greatly reduce the amount of calculation and accuracy. I also implemented analysis algorithm of fetal heart rate change based on normal fetal sample data in order to exact diagnosis.

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A case with GRIN2A mutation and its non-neurological manifestations

  • Lee, Soo Yeon;Jung, So Yoon;Lee, Jeongho
    • Journal of Genetic Medicine
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    • v.17 no.2
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    • pp.79-82
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    • 2020
  • In epilepsy-aphasia spectrum (EAS) disorders, mutations in the glutamate receptor ionotropic N-methyl-D-aspartate type subunit 2A (GRIN2A) have become important for screening the disease. Research into the phenotypic variability of several types of neurologic impairment involving these mutations is in progress. However, the non-neurological problems related to these mutations are poorly understood. EAS disorders usually have epileptic, cognitive, or behavioral manifestations. In this case report, we present a female patient with epilepsy, delay in expressive language and social development, and intellectual disability with low intelligence quotient and memory quotient, but normal motor development. Through genetic analysis, she was found to have a missense and a nonsense mutation in GRIN2A (c.1770A>C; p.Lys509Asn and c.3187G>T; p.Glu1063∗, respectively) and we consider the nonsense mutation as 'pathogenic variant'. She was also discovered to have congenital hypothyroidism, growth hormone deficiency and Rathke's cleft cyst in the brain, which were previously unknown features of GRIN2A mutation. Our findings should widen understanding of the spectrum of GRIN2A phenotypes, and emphasize the need for more research into the association between GRIN2A mutations and non-neurologic clinical presentations.

Evaluation Internal Radiation Dose of Pediatric Patients during Medicine Tests Using Monte Carlo Simulation (몬테칼로 시뮬레이션을 이용한 소아 핵의학검사 시 인체내부 장기선량 평가)

  • Lee, Dong-yeon;Kang, Yeong-rok
    • Journal of radiological science and technology
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    • v.44 no.2
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    • pp.109-115
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    • 2021
  • In this study, a physical evaluation of internal radiation exposure in children was conducted using nuclear medicine test(Renal DTPA Dynamic Study) to simulate the distribution and effects of the radiation throughout the tracer kinetics over time. Monte Carlo simulations were performed to determine the internal medical radiation exposure during the tests and to provide basic data for medical radiation exposure management. Specifically, dose variability based on changes in the tracer kinetic was simulated over time. The internal exposure to the target organ (kidney) and other surrounding organs was then quantitatively evaluated and presented. When kidney function was normal, the dose to the target organ(kidney) was approximately 0.433 mGy/mCi, and the dose to the surrounding organs was approximately 0.138-0.266 mGy/mCi. When kidney function was abnormal, the dose to the surrounding organs was 0.228-0.419 mGy/mCi. This study achieved detailed radiation dose measurements in highly sensitive pediatric patients and enabled the prediction of radiation doses according to kidney function values. The proposed method can provide useful insights for medical radiation exposure management, which is particularly important and necessary for pediatric patients.

A clinical perspective on the anatomical study of digastric muscle

  • Nandini Prashanth Bhat;Suhani Sumalatha;Ashwija Shetty;Sushma Prabhath
    • Anatomy and Cell Biology
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    • v.56 no.4
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    • pp.441-447
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    • 2023
  • One of the suprahyoid muscles is the digastric muscle which comprises anterior and posterior bellies joined by an intermediate tendon. Because of its close relationship with the submandibular gland, lymph nodes, and chief vessels of the neck, detailed knowledge about the morphometry of the digastric muscle is essential. The objective of the current cross-sectional evaluative study is to record morphometry along with the digastric muscle's origin, insertion, and variability. Forty human cadavers (25 males and 15 females) were dissected, and the head and neck regions were studied in detail. The attachment of the digastric muscle anterior belly to the digastric fossa of the mandible was noted, and the distal attachment of the posterior belly to the mastoid notch was traced. The length of the anterior belly from the digastric fossa to its intermediate tendon and the length of the posterior belly from the intermediate tendon to its mastoid attachment were measured. There is a fair correlation between the length of the neck and the length of the anterior and posterior belly. The study also identified two cases of bilateral accessory bellies of the anterior belly of the digastric. Normal morphometric data is provided by this study on details of the digastric muscle. It is significant from a clinical and surgical point of view as the muscle lies in proximity to the important structures of the neck.

Warm Season Hydro-Meteorological Variability in South Korea Due to SSTA Pattern Changes in the Tropical Pacific Ocean Region (열대 태평양 SSTA 패턴 변화에 따른 우리나라 여름철 수문 변동 분석)

  • Yoon, Sun-kwon;Kim, Jong-Suk;Lee, Tae-Sam;Moon, Young-IL
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.36 no.1
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    • pp.49-63
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    • 2016
  • In this study, we analyzed the effects of regional hydrologic variability during warm season (June-September) in South Korea due to ENSO (El $Ni{\tilde{n}}o$-Southern Oscillation) pattern changes over the Tropical Pacific Ocean (TPO). We performed composite analysis (CA) and statistical significance test by Student's t-test using observed hydrologic data (such as, precipitation and streamflow) in the 113 sub-watershed areas over the 5-Major River basin, in South Korea. As a result of this study, during the warm-pool (WP) El $Ni{\tilde{n}}o$ year shows a significant increasing tendency than normal years. Particularly, during the cold-tongue (CT) El $Ni{\tilde{n}}o$ decaying years clearly decreasing tendency compared to the normal years was appeared. In addition, the La $Ni{\tilde{n}}a$ years tended to show a slightly increasing tendency and maintain the average year state. In addition, from the result of scatter plot of the percentage anomaly of hydrologic variables during warm season, it is possible to identify the linear increasing tendency. Also the center of the scatter plot shows during the WP El $Ni{\tilde{n}}o$ year (+17.93%, +26.99%), the CT El $Ni{\tilde{n}}a$ year (-8.20%, -15.73%), and the La $Ni{\tilde{n}}a$ year (+8.89%, +15.85%), respectively. This result shows a methodology of the tele-connection based long-range water resources prediction for reducing climate forecasting uncertainty, when occurs the abnormal SSTA (such as, El $Ni{\tilde{n}}o$ and La $Ni{\tilde{n}}a$) phenomenon in the TPO region. Furthermore, it can be a useful data for water managers and end-users to support long-range water-related policy making.

Development of Automated Region of Interest for the Evaluation of Renal Scintigraphy : Study on the Inter-operator Variability (신장 핵의학 영상의 정량적 분석을 위한 관심영역 자동설정 기능 개발 및 사용자별 분석결과의 변화도 감소효과 분석)

  • 이형구;송주영;서태석;최보영;신경섭
    • Progress in Medical Physics
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    • v.12 no.1
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    • pp.41-50
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    • 2001
  • The quantification analysis of renal scintigraphy is strongly affected by the location, shape and size of region of interest(ROI). When ROIs are drawn manually, these ROIs are not reproducible due to the operators' subjective point of view, and may lead to inconsistent results even if the same data were analyzed. In this study, the effect of the ROI variation on the analysis of renal scintigraphy when the ROIs are drawn manually was investigated, and in order to obtain more consistent results, methods for automated ROI definition were developed and the results from the application of the developed methods were analyzed. Relative renal function, glomerular filtration rate and mean transit time were selected as clinical parameters for the analysis of the effect of ROI and the analysis tools were designed with the programming language of IDL5.2. To obtain renal scintigraphy, $^{99m}$Tc-DTPA was injected to the 11 adults of normal condition and to study the inter-operator variability, 9 researchers executed the analyses. The calculation of threshold using the gradient value of pixels and border tracing technique were used to define renal ROI and then the background ROI and aorta ROI were defined automatically considering anatomical information and pixel value. The automatic methods to define renal ROI were classified to 4 groups according to the exclusion of operator's subjectiveness. These automatic methods reduced the inter-operator variability remarkably in comparison with manual method and proved the effective tool to obtain reasonable and consistent results in analyzing the renal scintigraphy quantitatively.

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Numerical Study on Spring-Neap Variability of Net Volume Transport at Yeomha Channel in the Han River Estuary (한강하구 수로별 순 수송량과 대.소조기 변화에 따른 염하수로의 순 수송량 변동에 관한 수치해석적 연구)

  • Yoon, Byung-Il;Woo, Seung-Buhm
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.24 no.4
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    • pp.257-268
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    • 2012
  • The EFDC model with find grid resolution system connecting the Gyeong-Gi bay and Han River estuary was constructed to study on spring-neap variability of net volume transport at each channel of the Han River estuary. The simulation time of numerical model is 124 days from May to August, 2009 with freshwater discharge at Han, Imjin and Yeseong River. The calibration and verification of model results was confirmed using harmonic components of water level and tidal current. The net volume transport was calculated during 30 days with normal freshwater conditions at Seokmo channel and Yeomha channel around Ganghwado. The ebbing net volume transport of 44% and 56% is drained into Gyeong-Gi bay through Yeomha and Seokmo channel, respectively. The ebbing net volume transport nearby Seodo at Yeomha channel convergence flooding net volume transport at Incheon harbor, and drain (westward direction) through channel of tidal flat between Ganghwado and Yeongjongdo to the Gyeong-Gi bay. The averaged net volume transport during 4 tidal cycles was compared to variation of spring-neap periods of the Yeomha channel. The convergence position is moved up- and down-ward according to spring-neap variability. The movement of the convergence zone is appeared because 1) increasing of discharged rate tidal flat channel between Ganghwado and Yeongjongdo at the spring period, 2) The growth of barotropic forcing with downward direction at the spring tide, and 3) The strength of the baroclinic pressure gradient is greater than spring with mixing processes.

A Study on the Positive Emotional Effects on Heart Rate Variability - Focused on Effects of '2002 FIFA World Cup' Sports Event on Emotion and General Health of Korean People - (긍정적 감성경험에 의한 심박변이도의 변화에 대한 연구 - 2002 한일 월드컵 행사가 한국의 국민 정서와 건강에 미친 영향을 중심으로 -)

  • Jeong Kee-Sam;Lee Byung-Chae;Choi Whan-Seok;Kim Bom-Taeck;Woo Jong-Min;Lee Kwae-Hi;Kim Min
    • Science of Emotion and Sensibility
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    • v.9 no.2
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    • pp.111-118
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    • 2006
  • The purpose of the study is to examine the effects of the positive menial stress, eustress, on autonomic nervous system(ANS) and human health. For this, we analyzed heart rate variability(HRV) parameters, the most promising markers of ANS function to assess the changes of emotional and physiological states of human body. We measured HRV Signal of World Cup group(281 male subjects: $29.8{\pm}5.6yr$., 187 female subjects: $29.0{\pm}5.4yr$.) in two stadiums at least an hour before the game during '2002 FIFA World Cup Korea/Japan' event. We also measured control group's(331 male subjects: $30.9{\pm}4.7 yr$., 344 female subjects: $30.2{\pm}5.2 yr$.) in the health promotion centers in two university hospitals at least a month before and after the world cup event period. Considering physiological differences between males and females, the data analysis was applied to 'male group' and 'female group' separately. As a result, some tendency was observed that is different from what we have known as the stress reaction. In general, all parameter values except that of mean heart rate tend to decrease under stressed condition. However, under eustressed condition, both heart rate and standard deviation of the Normal to Normal intervals(SDNN) were higher then those of normal condition(p<0.05). Especially, in case of female group, contrary to distressed condition, every frequency-domain powers showed tile higher value(p<0.05, p<0.001). Considering that decrease of HRV indicates the loss of one's health, the increase of SDNN and frequency parameters means that homeostasis control mechanism of ANS is functioning positively. Accordingly, induction of eustress from international sports event may affect positively to the people's health.

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Comparative Analysis of Default Risk of Construction Company during Macroeconomic Fluctuations (거시경제변동 전후 건설기업의 부실화 비교분석 - IMF 외환위기 및 서브프라임 금융위기 전후를 중심으로 -)

  • Choi, Jae-Kyu;Yoo, Seung-Kyu;Kim, Jae-Jun
    • Korean Journal of Construction Engineering and Management
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    • v.13 no.4
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    • pp.60-68
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    • 2012
  • The past IMF foreign exchange crisis and subprime financial crisis had a big influence on variability of macroeconomics, even if the origin of its occurrence might be different. This not only had a significant infrequence on the overall industries, but also produced many insolvent companies by being closely linked with a management environment of an individual construction company leading the construction industry. Actually, the level of default risk of construction companies before and after fluctuation of macroeconomics gets to experience a rapid changing process, and a difference in reaction against shock exists according to each company. Accordingly, the purpose of this paper is to confirm the fluctuation process of the default risk of construction companies under the fluctuation of macroeconomics such as the IMF financial crisis and the subprime mortgage crisis. As an analysis result, it is judged that the subprime financial crisis gave bigger shock to construction companies than the foreign exchange crisis, and it is expected that this would have a relation with the construction market before shock of macroeconomics. In addition, it was analyzed that when comparing insolvent companies with normal companies, the recovery speed of normal companies is faster. It is judged that this was affected by a difference of internal business capacity between insolvent companies and normal companies.