• The Journal of Korean Physical Therapy
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• v.13 no.3
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• pp.537-549
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• 2001

The isometric torque of the elbow flexor and extensor muscles were measured for 6 seconds at a joint angle of 90$^{\circ}$ , in 10 normal subjects (control group) and 10 hemiplegic subjects(patient group), using the Cybex NORMTM System. The peak torque, the time to peak torque were measured for each exercise. In addition, heart rate and blood pressure were recorded simultaneously at rest and immediately following exercise completion at 1 and 3m mutes. Statistical analysis was performed using SPSS 8.0 for Windows software and mean and standard deviations were calculated. The results are as follows. 1) In the patient involved group. the isometric values for flexors and extensors were significantly lower than in the normal nondominant group(p<.05). 2) The extensor to flexor strength ratio in the isometric mode was 121.0% in the patient involved group compared with 78.7%in the normal nondominant group, a significant difference(p<.05). 3) The mean increment ratio was increased 19.0% for systolic blood pressure and 25.2% for disatolic blood pressure in the patient group. 4) The mean increment ratio was increased 36.0% heart rate in the patient group.

• Phonetics and Speech Sciences
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• v.6 no.4
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• pp.79-90
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• 2014

An intonation curve stylization was used for an acoustical analysis of English speech. For the analysis, acoustical feature values were extracted from 1,848 utterances produced with normal and fast speech rate by 28 (12 women and 16 men) native speakers of English. Men are found to speak faster than women at normal speech rate but no difference is found between genders at fast speech rate. Analysis of pitch point features has it that fast speech has greater Pt (pitch point movement time), Pr (pitch point pitch range), and Pd (pitch point distance) but smaller Ps (pitch point slope) than normal speech. Men show greater Pt, Pr, and Pd than women. Analysis of sentence level features reveals that fast speech has smaller Sr (sentence level pitch range), Sd (sentence duration), and Max (maximum pitch) but greater Ss (sentence slope) than normal speech. Women show greater Sr, Ss, Sp (pitch difference between the first pitch point and the last), Sd, MaxNr (normalized Max), and MinNr (normalized Min) than men. As speech rate increases, women speak with greater Ss and Sr than men.

• Journal of the Korean Society of Food Science and Nutrition
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• v.19 no.1
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• pp.27-34
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• 1990

This study was undertatken to investigate the effects of dietary vitamin E on the toxicity of cadmium(Cd) in rats. The two variables were the supplmentary vitamin E(400lU/kg) and the protein amount(10.5% in the low protein diet and 18.0% in the normal protein diet) In cadmium treated rats net weight gain and food intake were decreased but improved by supplementation with vitamin E in the normal protein, hematocrit values reduced by Cd were significantly increased by the addition of vitamin E to normal protein diet in Cd intoxicated rats, The supplementation with vitamin E diminished the effect of Cd on aspartate aminotransf-rase and alanine aminotransferase activities in serum In Cd treated rats fed normal protein diet with vitamin E the contents of triglyceride were decreased and total-cholesterol contents were significantly reduced in serum and both of them in liver were markedly decreased. The activity of alcohol dehydrogenase in liver was decreased by Cd however supplementation with vitamin E reduced the effects of Cd on hepatic alcohol dehydrogenase. the results of this experiment indicated that there was some interaction between vitamin E and protein levels and supplementation with vitamin E had an effect more than protein levels oncd toxicity.

• YAKHAK HOEJI
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• v.41 no.5
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• pp.622-628
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• 1997

Hepatic cirrhosis is a common response to chronic liver injury from many causes and is one of the most common cause of all deaths. This study was carried out to compare experimental hepatic cirrhosis in rats to understand this disease and to apply for the pharmacokinetics in disease state. Following three kinds of experimental models were induced; 1) Bile duct ligation/scission (BDL/S), 2) N, N-dimethylnitrosamine(DMN), 3) Carbon tetrachloride. The hepatic cirrhosis was characterized by examing the liver/body weight ratio, serum biochemical values, hydroxyproline content in liver and histopathological lesions in cirrhotic rat liver. The results are as follows : (1) In BDL/S, the liver was enlarged to 250% of normal liver. In contrast the liver was shrinked to 48% and 78% of the normal liver in DMN and carbon tetrachloride, respectively. (2) In carbon tetrachloride and BDL/S, the serum ALT, AST, ALP and total bilirubin levels were significantly increased to 200~300% of normal level, while ALT and total bilirubin levels were significantly increased in DMN group. (3) Hydroxyproline content in cirrhotic rat liver was significantly 200~500% higher than that of normal liver. (4) Nodular formation with fibrosis was observed in BDL/S, DMN, carbon tetrachloride induced cirrhotic rat liver.

• Journal of Biomedical Engineering Research
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• v.35 no.3
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• pp.68-74
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• 2014

Recent research on mild cognitive impairment (MCI) has shown that cognitive and memory decline in this disease is accompanied by disruptive changes in the brain functional network. However, there have been no graph-theoretical studies using $^{11}C$-PIB PET data of the Alzheimer's Disease or mild cognitive impairment. In this study, we acquired $^{18}F$-FDG PET and $^{11}C$-PIB PET images of twenty-four normal aging control participants and thirty individuals with MCI from ADNI (Alzheimer's Disease Neuroimaging Initiative) database. Brain networks were constructed by thresholding binary correlation matrices using graph theoretical approaches. Both normal control and MCI group showed small-world property in $^{11}C$-PIB PET images as well as $^{18}F$-FDG PET images. $^{11}C$-PIB PET images showed significant difference between NC (normal control) and MCI over large range of sparsity values. This result will enable us to further analyze the brain using established graph-theoretical approaches for $^{11}C$-PIB PET images.

• Steel and Composite Structures
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• v.7 no.4
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• pp.321-337
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• 2007

The investigation on the behaviour of cold-formed stainless steel non-slender circular hollow section columns is presented in this paper. The normal strength austenitic stainless steel type 304 and the high strength duplex materials (austenitic-ferritic approximately equivalent to EN 1.4462 and UNS S31803) were considered in this study. The finite element method has been used to carry out the investigation. The columns were compressed between fixed ends at different column lengths. The geometric and material nonlinearities have been included in the finite element analysis. The column strengths and failure modes were predicted. An extensive parametric study was carried out to study the effects of normal and high strength materials on cold-formed stainless steel non-slender circular hollow section columns. The column strengths predicted from the finite element analysis were compared with the design strengths calculated using the American Specification, Australian/New Zealand Standard and European Code for cold-formed stainless steel structures. The numerical results showed that the design rules specified in the American, Australian/New Zealand and European specifications are generally unconservative for the cold-formed stainless steel non-slender circular hollow section columns of normal and high strength materials, except for the short columns and some of the high strength stainless steel columns. Therefore, different values of the imperfection factor and limiting slenderness in the European Code design rules were proposed for cold-formed stainless steel non-slender circular hollow section columns.

• Korean Journal of Applied Biomechanics
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• v.17 no.3
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• pp.133-145
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• 2007

The purpose of this paper was to compare of difference between energy walking and normal walking. Subjects were selected 8 male undergraduates. The kinematic variables of a pelvis and a thorax were analysed at the take off and contact with 3d cinematography. In addition to the variables, the phase plot angle was calculated in order to definite characteristics in the phase space. The pelvic angle and angular velocity showed significant differences in the flexion/extension between two walking patterns. The pelvic angle and angular velocity were increasing when walking speed was increasing and magnitude of the variables of energy walking was larger than corresponding values for normal walking. On the other hand, the thoracic angle demonstrated significant differences in the flexion/extension and rotation between two walking patterns. The angles of energy walking were smaller in the flexion/extension and were larger in the rotation than the angle of normal walking. The kinematic characteristics of energy walking were also showed clearly significant differences in the range of motion and the relative angle of the trunk. The angle of phase plot only showed demonstrated a significant difference in the rotation at contact between the two walking patterns.

• Journal of Industrial and Engineering Chemistry
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• v.67
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• pp.373-379
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• 2018

A transparent, freestanding Porous Aromatic Framework-97 (PAF-97) membrane was successfully synthesized via a one-step acid-catalyzed reaction. Due to the introduction of ether groups, the obtained PAF-97 membrane possesses enhanced structural flexibility, thus increasing the flexibility of the resulting membrane. This is proofed by the fact that the feeding pressure of the membrane reaches as high as 5.5 bar during the separation of gas mixtures. The Young's moduli of the membrane were 6.615 GPa and 11.11 GPa, either in a dry or hydrated state respectively. To be highlighted, under a feeding pressure of 3.6 bar, the PAF-97 membrane rendered the permeance values of $2.90{\times}10^{-7}$, $1.29{\times}10^{-8}mol\;m^{-2}s^{-1}Pa^{-1}$ for $CO_2$ and $CH_4$, respectively, with a $CO_2/CH_4$ permselectivity of 22.48.

• Korean Journal of Plant Resources
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• v.18 no.2
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• pp.343-350
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• 2005

Effects of Oenanthe javanica Sap on lipid composition, liver function and oxidative capacity were investigated in rats fed oxidized fat and ethanol. Twenty male Sprague-Dawley rats weighing $183.49\;{\pm}\;2.47g$ were distributed into four groups according to body weight and raised seven weeks with basal diet (normal group), basal diet, $10\%$ oxidized fat and $50\%$ ethanol (control group), basal diet, $10\%$ oxidized fat, $50\%$ ethanol and 1 ml Oenanthe javanica Sap (1 ml Oenanthe javanica Sap group) and basal diet, $10\%$ oxidized fat, $50\%$ ethanol and 1.5 ml Oenanthe javanica Sap (1.5 ml Oenanthe javanica Sap group), Total cholesterol and triglyceride in plasma showed a tendency to decrease in Oenanthe javanica Sap groups. However HDL-cholesterol in plasma showed a high values in Oenanthe javanica Sap groups and showed no significant difference to normal group. The values of total cholesterol and triglyceride in liver showed no significant difference in Oenanthe javanica Sap groups and normal group. The values of thiobarbituric acid in plasma and liver were lowered in the Oenanthe javanica Sap groups with no significance. Plasma GOT and GPT activity showed a tendence to decrease in Oenanthe javanica Sap groups. The values of GSH-Px, SOD and CAT activity showed a tendence to increase in the Oenanthe javanica Sap groups.

• Journal of Korean Medicine Rehabilitation
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• v.21 no.1
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• pp.35-46
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• 2011

Objectives : The present study investigated inflammatory effect of Rheum undulatum L. in lipopolysaccharide-exposed rats and Raw 264.7 cells. Methods : Male rats weighting $185.39{\pm}8.21g$ fed basal diet for 1 week and 32 rats were divided into a control group and 3 experimental groups. We fed a control group of rats a basal diet and administered normal saline(100 mg/kg, 1time/1day) for 6 weeks. And we fed basal diet and administered an extract of Rheum undulatum L.(100 mg/kg, 200 mg/kg, 300 mg/kg, 1time/1day) to each experimental group of rats. We measured the plasma concentration of $IL-1{\beta}$($interleukin-1{\beta}$), IL-6 and $TNF-{\alpha}$(tumor necrosis $factor-{\alpha}$), liver cytokines, Raw 264.7 macrophages cytokines. Results : The plasma concentration of $IL-1{\beta}$, IL-6 and $TNF-{\alpha}$ peaked at 5h(hour) after LPS(lipopolysaccharides) injection, and the values of the Rheum undulatum L. extract groups were lower than those of the control group. In the increment of these cytokines concentration at 2h and 5h after LPS injection, the Rheum undulatum L. groups were lower than that of control group. The plasma concentration of IL-10 peaked at 5h after LPS injection, and the values of the Rheum undulatum L. extract groups were higher than those of the control group. In the increment of this cytokine concentration at 2h and 5h after LPS injection, the Rheum undulatum L. groups were higher than that of control group. Liver cytokines measurement was done at 5h after LPS injection. The concentration of liver $IL-1{\beta}$ and IL-6 in the Rheum undulatum L. groups was lower than that of the control group. The concentrations of liver $TNF-{\alpha}$, and IL-10 showed no significant differences among all the treatment groups. In the studies of lipopolysaccharide-exposed Raw 264.7 cells, the concentration of $IL-1{\beta}$, IL-6 and $TNF-{\alpha}$ in the lipopolysaccharide-exposed cells groups was higher than that of control group(normal group), and in the lipopolysaccharide-exposed cells groups, these values showed a tendency to decrease in the Rheum undulatum L. groups. The concentration of IL-10 in the lipopolysaccharide-exposed cells groups was higher than that of control group(normal group), and in the lipopolysaccharide-exposed cells groups, the values showed a tendency to increase in the Rheum undulatum L. groups. Conclusions : These results indicate that the Rheum undulatum L. extracts have an functional material for inflammatory activities.