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Effects of Oenanthe javanica Sap on Lipid Composition, Liver Function and Oxidative Capacity in Oxidized Fat and Ethanol Fed Rats  

Lee Eun (Department of bio-industry and technology, Sangji University)
Park Young-Hoon (Department of chemistry, Sangji University)
Lim Sang-Cheul (Department of Botany Resources Sangji University)
Publication Information
Korean Journal of Plant Resources / v.18, no.2, 2005 , pp. 343-350 More about this Journal
Abstract
Effects of Oenanthe javanica Sap on lipid composition, liver function and oxidative capacity were investigated in rats fed oxidized fat and ethanol. Twenty male Sprague-Dawley rats weighing $183.49\;{\pm}\;2.47g$ were distributed into four groups according to body weight and raised seven weeks with basal diet (normal group), basal diet, $10\%$ oxidized fat and $50\%$ ethanol (control group), basal diet, $10\%$ oxidized fat, $50\%$ ethanol and 1 ml Oenanthe javanica Sap (1 ml Oenanthe javanica Sap group) and basal diet, $10\%$ oxidized fat, $50\%$ ethanol and 1.5 ml Oenanthe javanica Sap (1.5 ml Oenanthe javanica Sap group), Total cholesterol and triglyceride in plasma showed a tendency to decrease in Oenanthe javanica Sap groups. However HDL-cholesterol in plasma showed a high values in Oenanthe javanica Sap groups and showed no significant difference to normal group. The values of total cholesterol and triglyceride in liver showed no significant difference in Oenanthe javanica Sap groups and normal group. The values of thiobarbituric acid in plasma and liver were lowered in the Oenanthe javanica Sap groups with no significance. Plasma GOT and GPT activity showed a tendence to decrease in Oenanthe javanica Sap groups. The values of GSH-Px, SOD and CAT activity showed a tendence to increase in the Oenanthe javanica Sap groups.
Keywords
Oenanthe javanica Sap; cholesterol; triglyceride; thiobarbituric acid; GSH-Px; SOD; CAT;
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