• Journal of the Korean Data and Information Science Society
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• 제11권2호
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• pp.139-155
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• 2000

An exclusive simulation study is conducted in computing means for order statistics in standard normal variate. Monte Carlo moments are used in Shapiro-Francia W' statistic computation. Finally, quantiles for Shapiro-Francia W' are generated. The study shows that in computing means for order statistics in standard normal variate, complicated distributions and intensive numerical integrations can be avoided by using Monte Carlo simulation. Lack of accuracy is minimal and computation simplicity is noteworthy.

• Journal of the Korean Data and Information Science Society
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• 제10권1호
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• pp.1-10
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• 1999

Table of the empirical quantiles for the well known Shapiro-Francia W' goodness of fit statistic is produced which is more accurate than the existing ones. Prediction equation for the quantiles of W' statistic for sample sizes 30 or more we developed. The process of computing the expected values for the standard normal variate is discussed. This work is intended to make the Shapiro-Francia W' statistic more accessible to the practitioner.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1998년도 하계학술대회 논문집 C
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• pp.868-870
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• 1998

This is Part II of a two part paper dealing with control design in petter systems using the method of normal forms. The companion paper (part I) [1] describes the general theory and control procedure. This paper depicts numeral results to show the validation of the proposed method and to observe the effects of controller setting changes.

• Molecules and Cells
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• 제23권1호
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• pp.30-38
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• 2007

Dipyrithione (2, 2'-dithiobispyridine-1, 1'-dioxide, PTS2), a pyrithione derivate, is highly bactericidal and fungicidal. In this study we examined its apoptotic effect on HeLa cells. PTS2 induced HeLa cell death in a dose and time dependent manner. ERK1/2 and p38 were markedly activated, but little JNK1/2 activation was detected. Suppression of p38 activation by SB203580 reduced the extent of apoptosis of the HeLa cells and also prevented induction of p21, release of cytochrome c, and cleavage of caspase-3 and PARP. Inhibition of ERK1/2 with PD98059 increased apoptosis, indicating that ERK1/2 activation has an anti-apoptotic effect on PTS2-induced HeLa cell apoptosis. PTS2 also inhibited murine sarcoma 180 and hepatoma 22 tumor growth in an animal tumor model. Our findings indicate that PTS2 possesses anti-tumor activity, that caspase-3 and poly (ADP-ribose) polymerase (PARP) are involved in PTS2-induced HeLa cell apoptosis and that ERK1/2 and p38 have opposing effects on this apoptosis.

• 부모자녀건강학회지
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• 제5권1호
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• pp.75-89
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• 2002

This study was conducted to compare the emotional state between the mothers with low-birth-weights and mothers with normal infants, and to analyze the effects of home visiting for the low-birth-weights in one city. Data were collected from 51 mothers with low-birth-weights and 90 mothers with normal infants to compare emotional state, and from 26 mothers with low-birth weights to evaluate the effect of home visiting care. Summaries of results were as follows; 1. In mothers with low-birth-weights, social support form others was significantly lower than those of mothers with normal infants. Although the differences were not significant, mothers with low-birth-weights have more stress and child rearing burden, and less maternal self-esteem than those of mothers with normal infants. 2. Mothers with low-birth-weights, the more burden, postpartum depression, and the less husbands' support they felt. When they had lower maternal self-esteem and lower husbands' support, child rearing burden was higher. Also there was significant negative correlation between maternal self-esteem and postpartum depression. 3. In mothers with low-birth-weights, the score of post-intervention stress, care-giving burden, and postpartum depression were somewhat decreased, and maternal self-esteem was increased than pre-intervention data, although they were not statistically significant. 4. Mothers' satisfaction on the home-visiting care was considered to be high. In summary, mothers with low-birth-weights had lower social support even though they experienced more stress than mothers with normal infants. Therefore, public health nurse in community should pay more attention to them.

• 대한수학회보
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• 제51권3호
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• pp.789-801
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• 2014

In this paper, we study the existence of ground state solutions for a class of non-resonant cooperative elliptic systems by a variant weak linking theorem. Here the classical Ambrosetti-Rabinowitz superquadratic condition is replaced by a general super quadratic condition.

• 한국영양학회:학술대회논문집
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• 한국영양학회 1995년도 추계학술대회 초록
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• pp.42-42
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• 1995

• 대한전기학회논문지
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• 제39권3호
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• pp.240-246
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• 1990

The security control can be defined as all control actions and counter-measures to return the operating state of the system to a normal state. In an emergency state, fault clearing and/or overload suppression is enabled as a security control in order to prevent the extension of the fault. In the alert state, counter-measures should be set up in advance for the dangerous points of the system operation in drder to protect the system from expected accidents. In the normal state, the routine scenario is conducted to analyze system state. In the decision-making of the classification of system states, the heuristic and experienced knowledge can be well applied and thus application of expert system to this area attains considerable achievements. In this study, it is attempted to extract empirical rules through heuristic analysis and establish the knowledge base. Finally, the incorporation method with the conventional program packages in proposed. The expert system is designed to select an appropriate method and to perform the corresponding package. The input data can be automatically set up by using the data base. The computation results can be automatically added to the data base.

• 동의생리병리학회지
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• 제18권1호
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• pp.206-213
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• 2004

This study was performed to evaluate the anticonvulsant, antioxidant effect of modified formulas Korean traditional medicine Gungchihwadam-Jeon(GCHDJ). The extract of GCHDJ was administered (p.o.) to mice for 14 days in anticonvulsant and antioxidant tests. The pretreatment of GCHDJ extract prohibited the pentylenetrazol(PTZ)-induced convulsion in PTZ-induced convulsion, lowered level of brain r-aminobutyric acid(GABA) was restored by the pretreatment of GCHDJ. Increased level of brain glutamic acid was lowered to normal state by GCHDJ, and increased activity of brain r-aminobutyric acid transaminase(GABA-T) was reduced by GCHDJ. In PTZ-induced convulsion, increased level of brain lipid peroxide was lowered to normal state by the pretreatment of GCHDJ. Increased activity of brain xanthine oxidase(XOD) was lowered to normal state by GCHDJ, and increased activity of brain aldehyde oxidase lowered to normal state by GCHDJ. In PTZ-induced convulsion, increased activities of superoxide dismutase(SOD) and catalase in brain were lowered by the pretreatment of GCHDJ, whereas increased level of glutathione and increased activity of gluthathione peroxidase in brain were not changed significantly. Above results suggest that GCHDJ have anticonvulsant. antioxidant effect. That seems to be strongly related with the levels of GABA, glutamate, lipid peroxide and the activities of GABA-T, XOD, aldehyde oxidase, SOD, catalase in brain tissue. From these results, GCHDJ could be applied to various convulsive disorders.

• Journal of Nutrition and Health
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• 제35권10호
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• pp.1060-1069
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• 2002

High insulin level is known to be a risk factor of coronary heart disease. High insulin level with normal glycemic control is known to be an indicator for insulin resistance. This study was aimed to find out the influencing factors for the fasting serum insulin levels in elderly females with normal glycemic control. One hundred thirty-eight older females aged over 60 years without diabetes medication and high blood HBA1c level were examined on the serum fasting insulin concentration, anthropometry and asked about nutrient intake and exercise habits. The elderly were categorized into 3 group according to the fasting insulin level. The high insulin group was in a state of hyperinsulinemia. Except vitamin C, the nutrient intakes showed no difference according to fasting serum insulin level. But the intakes of calorie and protein per kg body weight were significantly lower in the high insulin group. The intakes of most nutrients except vitamin B$_1$, C and niacin were lower than the korean RDA in all the insulin group. Especially, the intakes of vitamin B$_1$ and Ca were below 75% of the korean RDA. Weight, BMI, body fat percent, body fat mass and fat-free mass, circumferences of waist and hip, WHR of elderly females were significantly higher in the group with the highest insulin level. The body fat percent in the highest insulin group was 35.8%. showing a state of obesity. The high insulin group showed higher proportion of low exercise frequencies per week and short exercise duration. Therefore, the mean energy expenditure for exercise were lower in this group, showing a state of very low exercise activity. Age and waist circumference in elderly females could explain to the 14.5% variances of the fasting insulin level according to multiple stepwise regression. It can be concluded that aging and central body fat deposition influence independently the serum fasting insulin level in elderly females with normal glucose level.