• Journal of the Korea Society of Computer and Information
• /
• v.17 no.4
• /
• pp.31-39
• /
• 2012

On rainy days, water films form on wet road surfaces and reduce the braking force of vehicles, which often ends up in accidents. For safe driving, the road information signage provides information on road and weather conditions warning drivers of wet road conditions. Still, current information on road conditions is neither localized nor detailed but universal. The present study used the images on CCTVs installed on roads to compare the images of road surfaces in an attempt to suggest a mechanism determining factors that hamper safe driving based on the images. In the image comparison, a normal road image taken on a sunny day is used as an original image, against which road conditions occurring on rainy days are categorized and determined on a case-by-case basis to provide drivers with early warning for the sake of safe driving.

• YAKHAK HOEJI
• /
• v.45 no.3
• /
• pp.293-301
• /
• 2001

Genetically modified organism (GMO) using recombinant DNA technique has been exponentially increased, however there are still arguments for the safety of GM foods. The objective of this research was to compare the allergens of GM soybean(Roundup Ready$^{TM}$) with conventional soybeans. Each soybean extracts were prepared as crude extracts, heated extracts, and as heated and simulated gastric quid (SGF)-digested samples to characterize the stability of allergens to physicochemical treatment. Positive sera from 20 soybean-sensitive patients and control sera from 5 normal subjects were used to identify the endogenous allergens in soybeans. Specific-IgE binding activities to each soybean preparations were evaluated by ELISA and immunoblot technique. In ELISA result, IgE binding activities of positive sera to soy crude extracts generally showed two fold higher mean value than those of control sera, how-ever there was no significant difference between GM soybean and natural soybean varieties. Extracted proteins form each of the soybean preparations were separated with SDS-PAGE. The band pattern of GM soybean was very similar to those of natural soybean varieties. Immunoblots for the different soybeans revealed no differences in IgE-binding protein patterns, moreover, disclosed five prominent IgE-binding bands (75, 70, 50, 44 and 34 kDa) in crude extracts, four (75, 70, 44 and 34 kDa) in heated preparations, one (50 kDa) in heated and SGF-digested preparations. These IgE binding bands were consistent with previously reported results on the soybean. These results indicate that GM soybean (Roundup Ready$^{TM}$) is no different from natural soybean in terms of its allergen.gen.

• Journal of the Korean Chemical Society
• /
• v.47 no.6
• /
• pp.541-546
• /
• 2003

Experimental vapor pressure measurements available in the literature for the inert gases have been rigorously analyzed and used to evaluate the constants A, B, C, D, and exponent of the following equation in the form of reduced vapor pressure and reduced temperature : $InP_r=A+{\frac{B}{T_r}+CInT_r+DT_n^r}$ According to varying exponent n all four constants have been obtained for the inert gases by the error analysis. This has provided us the best n and four constants for each of the inert gases ; Argon, krypton, xenon, helium, and neon. In order to obtain the calculated vapor pressure by the above equation, only the normal boiling point and the critical pressure and critical temperature are necessary to get the vapor pressure for an overall average deviation of 0.31 % for 406 experimental vapor pressure points consisting of five gases available in the literature. The average deviation for argon, krypton, and xenon is 0.24%, 0.09%, and 0.22%, respectively, for neon 1.31% and for helium 0.61%. These results are not unexpected in view of the significant quantum effects associated with helium and to a lesser degree with neon.

• Applied Biological Chemistry
• /
• v.41 no.5
• /
• pp.337-341
• /
• 1998

The morphological and cultural characteristics of alkalophilic Coryneform bacteria TU-19 were investigated at various pHs. This bacterium showed normal growth pattern at $pH\;9.0{\sim}10.0$, but the cell growth was completely inhibited at extreme pH (12.0 or more). Interestingly, at pH 8.0 the morphology of the bacterial cells seems to form convoluted filaments during the exponential growth phase while at pH 10.0, the optimal pH for the growth of this organism, the bacteria grew with variable paired or single forms, and straight rods during growth stages. Growing in alkaline media $(pH\;9.0{\sim}11.0)$, it adjusted the pH of the culture media to around pH 8.5 by itself.

• The Korean Journal of Physiology and Pharmacology
• /
• v.21 no.6
• /
• pp.599-607
• /
• 2017

Most normal cells express L-type amino acid transporter 2 (LAT2). However, L-type amino acid transporter 1 (LAT1) is highly expressed in many tumor cells and presumed to support their increased growth and proliferation. This study examined the effects of JPH203, a selective LAT1 inhibitor, on cell growth and its mechanism for cell death in Saos2 human osteosarcoma cells. FOB human osteoblastic cells and Saos2 cells expressed LAT1 and LAT2 together with their associating protein 4F2 heavy chain, but the expression of LAT2 in the Saos2 cells was especially weak. JPH203 and BCH, a non-selective L-type amino acid transporter inhibitor, potently inhibited L-leucine uptake in Saos2 cells. As expected, the intrinsic ability of JPH203 to inhibit L-leucine uptake was far more efficient than that of BCH in Saos2 cells. Likewise, JPH203 and BCH inhibited Saos2 cell growth with JPH203 being superior to BCH in this regard. Furthermore, JPH203 increased apoptosis rates and formed DNA ladder in Saos2 cells. Moreover, JPH203 activated the mitochondria-dependent apoptotic signaling pathway by upregulating pro-apoptotic factors, such as Bad, Bax, and Bak, and the active form of caspase-9, and downregulating anti-apoptotic factors, such as Bcl-2 and Bcl-xL. These results suggest that the inhibition of LAT1 activity via JPH203, which may act as a potential novel anti-cancer agent, leads to apoptosis mediated by the mitochondria-dependent intrinsic apoptotic signaling pathway by inducing the intracellular depletion of neutral amino acids essential for cell growth in Saos2 human osteosarcoma cells.

• Preventive Nutrition and Food Science
• /
• v.13 no.3
• /
• pp.146-156
• /
• 2008

The enhancement of the human body fat reduction of conjugated linoleic acid (CLA) with the supplementation of $\gamma$-oryzanol (OZ) was investigated on overweight Korean women (n=51, BMI> 23). Subjects were divided into 4 groups of control, CLA, glyceride form of CLA (GCLA), and CLA plus OZ (CLA-OZ). The soft-gel capsule (500 mg) was used to deliver control (500 mg olive oil), CLA (500 mg CLA), GCLA (500 mg GCLA) and CLA-OZ (500 mg CLA plus 50 mg OZ). Three capsules were taken twice a day for 12 weeks. The CLA-OZ supplementation reduced 1.35% body fat that was 0.34% enhancement against CLA supplementation. As considered subject variations, CLA-OZ reduced body fat ranged from 7.9% to -2.7%, equivalent to 5.6 kg loss to 0.7 kg gain in body fat mass, against CLA. The CLA-OZ reduced body weight and body mass index (BMI), relative to control, but the reductions by CLA-OZ were not different from those by CLA and GCLA. All biochemical markers analyzed for safty were not significantly different within or between groups and were within the normal range. The CLA-OZ supplementation significantly reduced blood pressure, as compared to the supplementation of CLA, GCLA and control. These results suggest that OZ could be a useful ingredient to mix with CLA for the reduction of human body fat.

• Korean Journal of Clinical Pharmacy
• /
• v.3 no.1
• /
• pp.79-88
• /
• 1993

Bioequivalence(BE) test of commercially available sustained release tablets of diltiazem hydrochloride(DTZ) was performed to give some guidelines to BE test in korea in case of which drugs with low oral bioavaiiability(BA) due to substantial first-pass hepatic loss form pharmacologically active metabolites. In such cases, the pharmacologic activity after oral administration is greater than anticipated from BA data, based on chemical assay of drug alone. Therefore, this paper explores the use and meaning of area under the plasma concentration-time(AUC) data of parent and its metabolites to access BA if sustained release tablets. Normal healthy male volunteers(n=14) were randomly divided into 2 groups, and sustained release reference$(Herbesser^{(R)})$ and test$(Herben^{(R)})$ tablets of DTZ-30mg were given orally by balanced two-period cross-over dosing schedule. The plasma concentration of DTZ and and its active metabolite, desacetyldiitiazem(DAD), were determined by high performance liquid chromatography, and, $AUC_{DTZ},\;AUC_{DAD},\;AUC_{DTZ+DAD},\;C_{max}\;and\;T_{max}$ obtained. Analysis of varlance(ANOVA) showed that $AUC_{DTZ}\;and\;C_{max}$ passed the standard $(\alpha=0.05,\;1-\beta\geq0.8,\;\Delta\leq0.2)$ of BE test of korea, but $AUC_{DAD}$ was not satisfied from the standpoint of power. On the other hand, $AUC_{DTZ\midDAD}$ may be more avaliable than $AUC_{DAD}$ from the standpoint of statistics and pharmacologic equivalence.

• Journal of the Korea Convergence Society
• /
• v.8 no.3
• /
• pp.49-61
• /
• 2017

Recently, convenience and usability are increasing with the development and deployment of various mobile applications on the Android platform. However, important information stored in the smartphone is leaked to the outside without knowing the user since the malicious mobile application is continuously increasing. A variety of mobile vaccines have been developed for the Android platform to detect malicious apps. Recently discovered server-based polymorphic(SSP) malicious mobile apps include obfuscation techniques. Therefore, it is not easy to detect existing mobile vaccines because some other form of malicious app is newly created by using SSP mechanism. In this paper, we analyze the correlation between the similarity of the method in the DEX file constituting the core malicious code and the permission similarity measure through APK de-compiling process for the SSP malicious app. According to the analysis results of DEX method similarity and permission similarity, we could extract the characteristics of SSP malicious apps and found the difference that can be distinguished from the normal app.

• Journal of the korean academy of Pediatric Dentistry
• /
• v.25 no.3
• /
• pp.533-538
• /
• 1998

[ $Garr{\grave{e}}'s$ ] osteomyelitis is a chronic form of osteomyelitis in which periosteum is thickened with peripheral reactive bone formation. Carl $Garr{\grave{e}}$ first reported localized periosteal thickening as a response to mild stimuli. In dental literatures, Pell et al. first reported $Garr{\grave{e}}'s$ osteomyelitis in jaws. This disease frequent occurs in youngsters and usually in mandible. It usually results in hard swelling over the jaws with little or no pain. Palpation reveals a localized bony swelling lesion. In radiographic findings, it usually reveals laminated periosteal thickening on lesion. The treatment of $Garr{\grave{e}}'s$ osteomyelitis usually consists of elimination of the sources of infection, i.e., either extraction of an infected teeth or root canal therapy. Two children were admitted with the chief complaint of intraoral swelling on lower deciduous molar areas which was diagnosed as $Garr{\grave{e}}'s$ osteomyelitis. The root canal therapy and antibiotic therapy were performed and prognosis was checked. From these case studies, some results were obtained as follows : With the aid of root canal therapy and antibiotic administration, the size of periapical lesions was reduced, the mandible with bony swelling recovered its normal shapes radiographically, and the permanent tooth germs resumed sound development.

• Korean Institute of Interior Design Journal
• /
• v.14 no.3 s.50
• /
• pp.20-27
• /
• 2005

The built-in kitchen that is seen in every household is one of the achievements of the modernism architecture in early 20th century. Developed on the basis of two axis, one of which is the high industrialization and the other the sceptical assessment on the traditional value-system, the 20th century was launched in the form of the twofold entanglement, through the unfolding of which the cultural code of the modernism could be operated. The Quantification of the psychic that was attempted by H. v. Helmholtz and E. Mach in the pursuit of the reunification of sensation to the normal science was the first thread of that, while the second the break-down of the authoritative ideology and the emancipation of woman labour, which were initiated by the leftist movements. In this situation Margarete Schutte-Lihotzky was the woman architect who has tried to overcome the patriarchism in the household through architectural work by dwelling on that the emancipation of the housewives from the inefficient household labour is directly connected with the accomplishment of human freedom. She applied the modernist functionalism to the designing the kitchen for that purpose and outlined the effective range and operational realm of the rationalization. After all this the future preoccupying endeavor became the decisive moment that gave birth to a aesthetically and functionally good deliberated design of the kitchen in the present. This study is purposed to actualize the architectural ideas of Lihotzky into the present context through the consideration on the Frankfurt Kitchen of her and to grope for the relationship between architecture and feminism on the common horizon of the functionalist architecture and the women's liberation.