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Stability of 0ndansetron and Fluconazole in 5% Dextrose Injection and Normal Saline during Y-Site Administration

  • Burm, Jin-Pil
    • Archives of Pharmacal Research
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    • v.20 no.2
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    • pp.171-175
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    • 1997
  • The stability of ondansetron and fluconazole in 5% dextrose injection and normal saline during simulated Y-site injection at room temperature was studied. Ondansetron 0.03, 0.1 and 0.3 mg/ml were admixed 1:1 with fluconazole 2 mg/ml. The solutions were stored at room temperature and samples were retrieved at time 0, 1, 2, 4 and 12 hr for immediate assay. At the time of the assay and before any dilution, each sample was visually inspected for clarity, color, precipitation, and the pH was determined. Drug concentrations were measured by a stability-indicating high performance liquid chromatograph. Ondansetron 0.03, 0.1 and 0.3 mg/ml were stable when mixed with concentration of fluconazole 2 mg/ml. There were no change in clarity and color and no precipitates in any admixture for 12 hr of inspection. The pH measurements did not have a particular trend in any direction over time.

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Preparation of Ceria-stabilized Zirconia Ceramics with Irregular Grain Shape (불규칙 입자형상을 갖는 세리아 안정화 지르코니아 세라믹스의 제조)

  • 강현희;이종국
    • Journal of the Korean Ceramic Society
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    • v.36 no.4
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    • pp.372-379
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    • 1999
  • Hihg-toughened ceria-stabilized tetragonal zirconia ceramics with irregular grain shape and undulated grain boundary was prepared by ceria doping. Irregularity of grain shapes was increased with the amount of doped ceria. But in case of the large amount of doped ceria grain boundary was migrated to the reverse direction of DIGM. Ceria-stabilized zirconia ceramics annealed at 1650$^{\circ}C$ for 2h after twice dippings into cerium nitrate solu-tion of 0.2M and sintering at 1500$^{\circ}C$ for 2h showed the highest grain boundary length with a value of 23.6$\mu\textrm{m}$ Ceria concentration difference between convex and concave sides in irregular grains was observed over 1 mol% but not observed in normal grains, Specimens with normal grain shape showed intergranular fracture mode whereas the specimens with irregular grain shape showed transgranular fracture mode.

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Film Compensation based on Discotic Film in Fringe Field Switching Mode

  • Hwang, Seong-Han;Jung, Byoung-Sun;Kim, Seong-Su;Lee, Seung-Hee;Lee, Gi-Dong
    • 한국정보디스플레이학회:학술대회논문집
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    • 2007.08a
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    • pp.527-530
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    • 2007
  • Film compensation to suppress a light leakage in the dark state of fringe-field switching (FFS) at off normal direction was performed by optimizing retardation value of discotic (negative A) and TAC films including in-plane switching (IPS). The normal FFS mode shows wide viewing angle characteristics that region of CR 10:1 is over $70^{\circ}$ of polar angle in all directions. The optimized FFS cell exhibits much better performances than other methods do in terms of CR and color uniformity.

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Turbulence Generation by Ultrasonically Induced Gaseous Cavitation in the $CO_2$Saturated Water Flow

  • Lee, Seung-Youp;Park, Young-Don
    • Journal of Mechanical Science and Technology
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    • v.17 no.8
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    • pp.1203-1210
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    • 2003
  • Emission of ultrasonic vibration to turbulent flow promotes the turbulence generation due to the resonantly oscillating pressure field and thereby induced cavitation. In addition, ultrasonic vibration is well transmitted through water and not dissipated easily so that the micro-bubbles involved in the fluid induce the gaseous cavitation if the bubbles are resonated with the ultrasonic field. In the present study, we found through LDV measurement that the gaseous cavitation induced by ultrasonic vibration to CO$_2$saturated water flow in the rectangular cross-sectioned straight duct enhances turbulence much more than the case of non-ultrasonic or normal ultrasonic conditions without gaseous cavitation. We also found that the fluctuating velocity component induced by emitting the ultrasonic vibration in normal direction of a rectangular channel flow can be redistributed to stream-wise component by the agitation of gaseous cavitation.

Analysis of the False Diffusion Effects in Numerical Simulation of Diesel Spray Impinging on Inclined Walls (경사진 벽충돌 디젤 분무에 대한 수치해석에서 오류확산이 미치는 영향)

  • Gwon, H.R.;Lee, S.H.
    • Journal of ILASS-Korea
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    • v.13 no.1
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    • pp.22-27
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    • 2008
  • The false diffusion occurs generally when the flow is oblique to the grid lines and when there is a non-zero gradient of the dependent variable in the direction normal to the flow. This numerical problem can overestimate diffusion terms in the continuous phase, causing the numerical inaccuracy for the simulation of impinging sprays on inclined walls because most of spray calculation uses rectangular grid system. Therefore, the main objective of this article is to investigate numerically the influence of false diffusion on numerical simulation for spray-wall impingement on inclined walls. It is found that unlike the spray impingement normal to the wall, the numerical diffusion exists in the case when diesel sprays impinge on the inclined walls with different angles. The results show that the correction function should be considered for accurate prediction of spray penetration length and more elaborate numerical schemes should be utilized to reduce the false diffusion.

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Corrosion and Wear Properties of Cold Rolled 0.087% Gd-Lean Duplex Strainless Steels for Neutron Absorbing Material (중성자 흡수소재용 냉간 압연된 Gd-저합금 이상 스테인레스 강의 부식 및 마모성)

  • Baek, Yeol;Choe, Yong
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2015.05a
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    • pp.123-123
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    • 2015
  • 0.087 wt.% Gd-lean duplex stainless steels were inert arc-melted and cast in a mold. The micro-hardnesses of the rolling, transverse, short transverse directions were 258.5, 292.3, 314.7 HV, respectively. The 33% cold rolled specimen had the crystallographic texture that mainly (100) pole was concentrated to normal direction and (110) pole was concentrated in the center of normal and rolling directions. The corrosion potential and corrosion rate in artificial sea water were in the range of $105.6-221.6mV_{SHE}$, $0.59-1.06mA/cm^2$, respectively. The friction coefficient and wear loss of the 0.087 wt.% Gd-lean duplex stainless steels in artificial sea water were about 67% and 65% lower than in air, whereas, the wear efficiency was 22% higher. The corrosion and wear behaviors of the 0.087 wt.% Gd-lean duplex stainless steels significantly depended on the gadolinium phases.

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Evolution of strain states during Cross-roll rolling in AA 5052 sheet using Finite Element Method (유한요소 해석을 통한 AA 5052 판재의 Cross-roll 압연시 변형율 상태의 변화)

  • Kim, S.H.;Kim, D.G.;Park, E.S.;Lee, J.S.;Huh, M.Y.
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2008.05a
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    • pp.404-407
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    • 2008
  • In the present work, cross-roll rolling was carried out using a rolling mill in which the roll axis is tilted by $7.5^{\circ}$ towards the transverse direction of the rolled sample. The evolution of strain states during cross-roll rolling was investigated by three-dimensional finite element method (FEM) simulation. Parallel to cross-roll rolling, normal-rolling using a conventional rolling mill was also carried out in the same rolling condition for clarifying the effect of cross-roll rolling. It turned out that three shear rate components were all introduced to the rolled sample by the cross-roll rolling process, while only one shear rate component operated during normal-rolling.

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Effect of Flow Inlet or Outlet Direction on Air-Water Two-Phase Distribution in a Parallel Flow Heat Exchanger Header

  • Kim, Nae-Hyun;Kim, Do-Young;Cho, Jin-Pyo;Kim, Jung-Oh;Park, Tae-Kyun
    • International Journal of Air-Conditioning and Refrigeration
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    • v.16 no.2
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    • pp.37-43
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    • 2008
  • The air and water flow distributions are experimentally studied for a round header - ten flat tube configuration. Three different inlet orientation modes (parallel, normal, vertical) were investigated. Tests were conducted with downward flow configuration for the mass flux from 70 to $130kg/m^2s$, quality from 0.2 to 0.6, non-dimensional protrusion depth (h/D) from 0,0 to 0.5. It is shown that, for almost all the test conditions, vertical inlet yielded the best flow distribution, followed by normal and parallel inlet. Possible explanation is provided using flow visualization results.

SEMI-INVARINAT SUBMANIFOLDS OF CODIMENSION 3 SATISFYING ${\nabla}_{{\phi}{\nabla}_{\xi}{\xi}}R_{\xi}=0$ IN A COMPLEX SPACE FORM

  • Ki, U-Hang
    • East Asian mathematical journal
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    • v.37 no.1
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    • pp.41-77
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    • 2021
  • Let M be a semi-invariant submanifold of codimension 3 with almost contact metric structure (��, ξ, η, g) in a complex space form Mn+1(c), c ≠ 0. We denote by Rξ = R(·, ξ)ξ and A(i) be Jacobi operator with respect to the structure vector field ξ and be the second fundamental form in the direction of the unit normal C(i), respectively. Suppose that the third fundamental form t satisfies dt(X, Y ) = 2��g(��X, Y ) for certain scalar ��(≠ 2c)and any vector fields X and Y and at the same time Rξ is ��∇ξξ-parallel, then M is a Hopf hypersurface in Mn(c) provided that it satisfies RξA(1) = A(1)Rξ, RξA(2) = A(2)Rξ and ${\bar{r}}-2(n-1)c{\leq}0$, where ${\bar{r}}$ denotes the scalar curvature of M.

SEMI-INVARIANT SUBMANIFOLDS OF CODIMENSION 3 IN A COMPLEX SPACE FORM IN TERMS OF THE STRUCTURE JACOBI OPERATOR

  • Ki, U-Hang;Kurihara, Hiroyuki
    • Communications of the Korean Mathematical Society
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    • v.37 no.1
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    • pp.229-257
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    • 2022
  • Let M be a semi-invariant submanifold of codimension 3 with almost contact metric structure (𝜙, 𝜉, 𝜂, g) in a complex space form Mn+1(c), c ≠ 0. We denote by A and R𝜉 the shape operator in the direction of distinguished normal vector field and the structure Jacobi operator with respect to the structure vector 𝜉, respectively. Suppose that the third fundamental form t satisfies dt(X, Y) = 2𝜃g(𝜙X, Y) for a scalar 𝜃(< 2c) and any vector fields X and Y on M. In this paper, we prove that if it satisfies R𝜉A = AR𝜉 and at the same time ∇𝜉R𝜉 = 0 on M, then M is a Hopf hypersurface of type (A) provided that the scalar curvature s of M holds s - 2(n - 1)c ≤ 0.