• 한국수학교육학회지시리즈D:수학교육연구
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• 제16권2호
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• pp.137-154
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• 2012

Comparative studies on mathematical modeling cognition feature were carried out between 15 excellent high school third-grade science students (excellent students for short) and 15 normal ones (normal students for short) in China by utilizing protocol analysis and expert-novice comparison methods and our conclusions have been drawn as below. 1. In the style, span and method of mathematical modeling problem representation, both excellent and normal students adopted symbolic and methodological representation style. However, excellent students use mechanical representation style more often. Excellent students tend to utilize multiple-representation while normal students tend to utilize simplicity representation. Excellent students incline to make use of circular representation while normal students incline to make use of one-way representation. 2. In mathematical modeling strategy use, excellent students tend to tend to use equilibrium assumption strategy while normal students tend to use accurate assumption strategy. Excellent students tend to use sample analog construction strategy while normal students tend to use real-time generation construction strategy. Excellent students tend to use immediate self-monitoring strategy while normal students tend to use review-monitoring strategy. Excellent students tend to use theoretical deduction and intuitive judgment testing strategy while normal students tend to use data testing strategy. Excellent students tend to use assumption adjustment and modeling adjustment strategy while normal students tend to use model solving adjustment strategy. 3. In the thinking, result and efficiency of mathematical modeling, excellent students give brief oral presentations of mathematical modeling, express themselves more logically, analyze problems deeply and thoroughly, have multiple, quick and flexible thinking and the utilization of mathematical modeling method is shown by inspiring inquiry, more correct results and high thinking efficiency while normal students give complicated protocol material, express themselves illogically, analyze problems superficially and obscurely, have simple, slow and rigid thinking and the utilization of mathematical modeling method is shown by blind inquiry, more fixed and inaccurate thinking and low thinking efficiency.

• Korean Journal of Radiology
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• 제22권7호
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• pp.1152-1162
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• 2021

Objective: This study aimed to determine whether there are regional differences in the blood-brain barrier (BBB) permeability of cognitively normal elderly participants and to identify factors influencing BBB permeability with a clinically feasible, 10-minute dynamic contrast-enhanced (DCE) MRI protocol. Materials and Methods: This IRB-approved prospective study recruited 35 cognitively normal adults (26 women; mean age, 64.5 ± 5.6 years) who underwent DCE T1-weighted imaging. Permeability maps (K_trans) were coregistered with masks to calculate the mean regional values. The paired t test and Friedman test were used to compare Ktrans between different regions. The relationships between K_trans and the factors of age, sex, education, cognition score, vascular risk burden, vascular factors on imaging, and medial temporal lobar atrophy were assessed using Pearson correlation and the Spearman rank test. Results: The mean permeability rates of the right and left hippocampi, as assessed with automatic segmentation, were 0.529 ± 0.472 and 0.585 ± 0.515 (K_trans, x 10^-3 min^-1), respectively. Concerning the deep gray matter, the K_trans of the thalamus was significantly greater than those of the putamen and hippocampus (p = 0.007, p = 0.041). Regarding the white matter, the K_trans value of the occipital white matter was significantly greater than those of the frontal, cingulate, and temporal white matter (p < 0.0001, p = 0.0007, p = 0.0002). The variations in K_trans across brain regions were not related to age, cognitive score, vascular risk burden, vascular risk factors on imaging, or medial temporal lobar atrophy in the study group. Conclusion: Our study demonstrated regional differences in BBB permeability (K_trans) in cognitively normal elderly adults using a clinically acceptable 10-minutes DCE imaging protocol. The regional differences suggest that the integrity of the BBB varies across the brains of cognitively normal elderly adults. We recommend considering regional differences in K_trans values when evaluating BBB permeability in patients with neurodegenerative diseases.

• Clinical and Experimental Pediatrics
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• 제55권5호
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• pp.159-163
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• 2012

Most children with epilepsy are of normal intelligence. However, a significant subset will have temporary or permanent cognitive impairment. Factors that affect cognitive function are myriad and include the underlying neuropathology of the epilepsy, seizures, epileptiform discharges, psychosocial problems, age at seizure onset, duration of epilepsy, and side effects associated with antiepileptic drugs. This review article discusses cognitive function in children with idiopathic epilepsy and the effects of antiepileptic drugs on cognitive function in children.

• 대한의료기공학회지
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• 제11권1호
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• pp.221-235
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• 2009

This study is made for the survey of the effectiveness of the auricular reflexology, now accepted as a part of alternative medicine, applied to the patients of musculoskeltal disease patients, and data about its cognition and the success rate of the therapy. 106 patient was employed in this study who works in various part in a company in Jun-ju in Junrabukdo. From them, data such as, musculoskeletal symptoms by questionnaire examination, and data from ear inspections and interviews were collected and used for the basal data. Auricular reflexology therapies were applied to them at the areas that reflect the musculoskeletal system, for five times, each time with intervals of three or four days. The data about the effectiveness were collected by questionnaire examination, including descriptive answers. The results are as follows; cognition to the auricular reflexology was 62.3%, and acceptance rate of this method was 81.1%. From this results, I think that this therapy can be easily acceptable. The success rates of this therapy were 32.1% after 1 time application, and 84.9% after 5 times applications. This result shows that auricular reflexology therapy has therapeutic effect in musculoskeletal diseases, and the success rates increase according to the application times. Between sex, its success rate were 80% in male patients, and 88.5% in female patients, so this therapy is rather more effective in female patients. According to the body weight, the success rate were 85.8% in normal weight patients, and 71.5% in over- weight patients, so this therapy is more effective in normal weight patients. Comparisons according to other factors, such as age, marriage state etc. shows no definite differences. Conclusively, I think that auricular reflex therapy is easy and useful preventative and treatment method in our usual life. With more investigation, we can apply this method to other musculoskeletal diseases and to the diseases of other systems in the body, I hope so.

• 성인간호학회지
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• 제27권6호
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• pp.656-664
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• 2015

Purpose: The purposes of this study were to identify the rate of reversion from mild cognitive impairment (MCI) to normal cognition (NC) among the community-dwelling elderly and to determine if there were differences in cognitive function, leisure activities, and exercises between the group with MCI-maintained and the group with reversion to NC. Methods: This study utilized a longitudinal descriptive comparative design. A total of 346 subjects over age 65 was recruited from public health center at baseline. Finally 152 elderly were enrolled at 1 year follow-up. Data were collected through MoCA-K, K-MMSE, KDSQ-C5 and questionnaires on leisure activities and exercises. Data were analyzed by IBM SPSS Statistics 21.0 using descriptive statistics, $x^2$ test, and t-test. Results: The rate of reversion from MCI to NC among the subjects was 44.1%. At baseline, the group with MCI-maintained had lower cognitive function than the group with reversion to NC. At 1 year follow-up, the group with reversion to NC had higher subjective cognitive function than the group with MCI-maintained. Regarding leisure activities, there were differences between the groups at baseline and 1 year follow-up. Conclusion: It is suggested that age, education year, subjective cognitive function, and leisure activities should be considered at planning a nursing intervention for MCI.

• 대한한방내과학회지
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• 제28권4호
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• pp.838-849
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• 2007

Backgrounds & Objectives : The aim of study was to evaluate post stroke cognitive deficit. We applied CERAD-K for post-stroke cognitive deficit, and revalued after treatment for 4 weeks. Methods : We applied CERAD-K test to 25 patients with post stroke cognitive deficit and compared with previous literature. After acupuncture treatment, moxa treatment, herb medicines, physical and occupational therapy for 4 weeks, we revalued changes by CERAD-K to 13 people that received treatment. Results : The stroke group's points were lower than the normal group in general cognition. Verbal fluency, MMSE-KC, and constructional praxis scores was lower than the AD group. Boston Naming Test, word list immediate recall, word list delayed recall, wordlist recognition, and praxis delayed recall scores were higher than the AD group. Verbal fluency (p=0.017), MMSE-KC (p=0.026), and word list immediate recall (p=0.005) scores of 13 patients participating in this study showed a statistically significant increase after treatment. Conculsions : Acupuncture treatment, moxa treatment, herb medicines, physical and occupational therapy are effective for improvement of post-stroke cognitive deficit, but this study could not demonstrate whether some treatments influenced cognition and there was a limitation in lacking a control group.

• 한국콘텐츠학회논문지
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• 제17권2호
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• pp.384-393
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• 2017

본 연구는 학령기 경계선 지능 아동을 대상으로 Q방법론을 적용하여 '학교'에 대한 주관적 인식유형과 특성을 파악하고자 하였다. Q표본은 학계 및 현장전문가 4인, 경계선 지능 아동 4인에 대한 심층면접과 관련 문헌고찰을 통해 21개를 선정하였고, P표본은 초등학교에 재학 중인 경계선 지능 아동 총 18명의 학부모와 본인의 동의를 거쳐 표집하였다. P표본은 5점 척도의 정규분포로 Q분류를 실시하였고 수집된 데이터는 Quanl PC 프로그램을 통해 분석하였다. 연구결과 학령기 경계선 지능아동의 학교에 대한 태도유형은 '참여적-의존형'과 '방관적-위축형'의 두 가지 유형으로 도출되었다. 본 연구결과를 통해 학교에 대한 태도는 아동의 자존감 및 가족 지지환경의 양상에 따라 달라질 수 있으며 각 유형별 소속감의 욕구와 안전의 욕구에 대한 적절한 교육복지적 개입이 필요함을 알 수 있었다. 본 연구결과는 경계선 지능아동의 학교에 대한 주관적 유형을 구체화함으로써 경계선 지능 아동이 초등교육을 통해 중등교육 이상의 교육 권리와 학습의 질을 유지하도록 돕기 위한 교육중재 방안에 기초자료를 제공했다는 점에서 함의가 있다.

• 한국콘텐츠학회논문지
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• 제12권8호
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• pp.310-317
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• 2012

본 연구의 목적은 노인의 인지건강을 유지 증진하는 효과가 있는 것으로 밝혀진 인지건강증진 프로그램을 집단을 대상으로 적용하여 그 효과를 확인하며, 또한 소집단과 대집단으로 구분된 집단의 크기에 따른 효과의 차이를 비교하는데 있다. 연구의 대상자는 치매로 진단받지 않은 60세 이상의 노인 377명으로 인천광역시 각 구 보건소를 통해 모집하였다. 연구 결과 소집단과 대집단 모두에서 노인의 인지기능 증진과 삶의 질 향상에 유의미한 효과가 있었으며, 우울의 감소에는 그 효과가 확인되지 않았다. 개별로 적용되어 효과가 밝혀진 인지건강증진 프로그램은 다양한 크기의 집단을 대상으로 실시하여도 노인의 인지건강과 삶의 질 향상에 그 효과가 있음을 밝힘으로서, 보다 많은 노인들에게 이 프로그램을 확대 적용할 수 있는 실질적 근거를 확인할 수 있었다.

• 한국노년학
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• 제30권3호
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• pp.743-757
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• 2010

마음이론이란 자기 자신과 타인의 믿음, 바람, 의도와 같은 마음 상태를 추론하는 능력을 가리킨다. 마음이론에 대한 대다수의 연구는 아동과 자폐증 환자에 초점을 맞춘 것이었으나 정상적인 노화 과정을 겪고 있는 노인과 치매 노인을 대상으로 한 연구도 이루어지고 있다. 본 논문에서는 마음이론의 노화에 대한 기존 연구 결과들을 개관하고 신경영상 기법의 활용과 실생활에 근거한 마음이론 측정 과제의 적용과 같은 향후 연구 방향을 제안한다. 아직까지 마음이론 능력의 노화가 다른 인지적 측면과 어떻게 관련되어 있는가와 같은 문제에 대해 논쟁이 이루어지고 있기는 하지만 마음이론의 관점에 근거한 노화 연구는 노인의 인지적 기능과 사회적 기능에 대한 이해를 증진시킬 것으로 기대된다.

• 생물정신의학
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• 제21권1호
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• pp.1-13
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• 2014

Normal aging causes changes in the brain volume, connection, function and cognition. The brain changes with increases in age and difference of gender varies at all levels. Studies about normal brain aging using various brain magnetic resonance imaging (MRI) variables such as gray and white matter structural imaging, proton spectroscopy, apparent diffusion coefficient, diffusion tensor imaging and functional MRI are reviewed. Total volume of brain increases after birth but decreases after 9 years old. During adulthood, total volume of brain is relatively stable. After 35 years old, brain shrinks gradually. The changes of gray and white matters by aging show different features. N-acetylaspartate decreases or remains unchanged but choline, creatine and myo-inositol increase with aging. Apparent diffusion coefficient decreases till 20 years old and then becomes stable during adulthood and increase after 60 years old. Diffusion tensor properties in white matter tissue are variable during aging. Resting-state functional connectivity decreases after middle age. Structural and functional brain changes with normal aging are important for studying various psychiatric diseases such as dementia, schizophrenia and bipolar disorder. Our review may be helpful for studying longitudinal changes of these diseases and successful aging.