• Clinical and Experimental Pediatrics
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• 제61권10호
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• pp.327-331
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• 2018

Purpose: The incidence of inflammatory bowel disease (IBD) is rapidly increasing, and several reports have described the renal complications of IBD. We sought to evaluate the clinical manifestations of renal complications in children with IBD in order to enable early detection and prompt treatment of the complications. Methods: We retrospectively reviewed the medical records of 456 children and adolescents aged <20 years who had been diagnosed with IBD since 2000. We analyzed patient age, sex, medication use, IBD disease activity, and clinical manifestations of renal symptoms. Results: Our study comprising 456 children with IBD included 299 boys (65.6%) and 157 girls (34.4%). The study included 346 children with Crohn disease and 110 children with ulcerative colitis. The incidence of kidney-related symptoms was 14.7%, which was significantly higher than that in normal children. We observed 26 children (38.8%) with isolated hematuria, 30 children (44.8%) with isolated proteinuria, and 11 children (16.4%) with hematuria and concomitant proteinuria. A renal biopsy was performed in 7 children. Histopathological examination revealed immunoglobulin A nephropathy in 5 children (71.4%). All children presented with mild disease and well-controlled disease activity of IBD. Conclusion: Children with IBD are more likely to show kidney-related symptoms than healthy children and adolescents are. Therefore, regular screening of urine and evaluation of renal function in such children are necessary for early detection of renal complications.

• 대한불안의학회지
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• 제2권1호
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• pp.50-55
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• 2006

Objectives : In the psychiatry, structured interview is very important tool to be used in epidemiological or psychopharmacological studies. However, investigators often find that the administration of comprehensive diagnostic interviews is time-consuming and expensive to be used in clinical or research settings. Considering these points, Sheehan and his colleagues developed MINI (Mini International Neuropsychiatric Interview) to meet the need for a brief, reliable, and valid structured diagnostic interview for psychiatric disorders. The MINI has been translated into many languages and used in many countries. Therefore, we translated the MINI into Korean and determined its validity in this study. Methods : Twohundred seventy patients and normal subjects participated in the validation of the MINI versus an expert's professional opinion. Schizophrenia and other psychotic disorders, mood disorders including major depressive disorder and bipolar disorder, anxiety disorders including panic and other phobic disorders, and alcohol dependence were included in this study. The validity was obtained by examination whether MINI based diagnoses were compatible with diagnoses by expert psychiatrists. Results : The range of Kappa values was 0.22 (somatoform disorder) to 0.93 (bipolar disorder - past). Overall agreement between MINI and expert's diagnoses were good. The Kappa values for anxiety disorders seemed to be higher than those for other disorders. Conclusion : The MINI Korean version has the good validity. It also has potential applications as a diagnostic tool for psychiatric disorders.

• 한국의상디자인학회지
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• 제22권3호
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• pp.99-110
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• 2020

In terms of junior high school girls' growth patterns during early adolescence, are unlike childhood when relatively balanced growth patterns are found and high school years in which the normal adult body type is nearly reached, growth patterns displayed are imbalanced and rapid. In fact, diverse size changes by body part growth occur significantly different from individual to individual. Therefore, it has been hard for junior high school students to select their proper size when buying school uniforms. This study attempted to acquire basic data needed to address adolescent body shapes and school uniform patterns for junior high school girls, using the data from the 7th Size Korea Survey (2015). Specifically, it provides basic data for the development of school uniform patterns through the classification of their body into particular types, After extracting body shape components and a cluster analysis using ANOVA. According to a factor analysis conducted to determine body shape components, six factors were obtained: Factor 1: bulk and horizontal size, Factor 2: body height and length, Factor 3: shoulder shape and length, Factor 4: shape of upper body, Factor 5: lower drop, Factor 6: upper drop with a variance of 81.46%. To classify junior high school girls' body shape and determine their characteristics, a cluster analysis was performed with the variables obtained using factor analysis. Body shape was classified into three different types: Type 1 accounted for 30.7%. This was a short, slender body with the smallest bulk, size, and upper drop. Type 2 accounted for 24.9%. This was the largest in bulk and horizontal size and highest and length as well. Type 3 accounted for 44.5%. This type was close to average in terms of horizontal size, length and height, and high drop values. To develop school uniforms with great accuracy and body fit for junior high school students, there should be further studies on changes in body shape and their causes. The study results can serve as basic data for comparing branded school uniform patterns for junior high school girls and developing school uniform patterns based on body shape, using 3D virtual clothing simulations.

• Journal of Trauma and Injury
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• 제19권1호
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• pp.47-53
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• 2006

Purpose: Recently, the American Heart Association recommended that routine cervical spine protection in submerged patients was not necessary, except in high-energy injury situations. However, until now, this recommendation has few supportive studies and literatures. This retrospective study was performed to demonstrate the risk of cervical spine injury in patients who had been submerged in a river. Methods: Seventy-nine submerged patients who visited St. Mary's Hospital between January 2000 and December 2005 were included in this retrospective study. We investigated and analyzed the victim's age, sex, activity on submersion, mental status and level of severity at admission, prognosis at discharge, associated injuries, and risk group by using the medical records and cervical spine lateral images. According to the activity on submersion, victims were classified into three groups: high risk, low risk, and unknown risk. The reports of radiologic studies were classified into unstable fracture, stable fracture, sprain, degenerative change, and normal. Results: The patients' mean age was 36.8 yrs, and 54% were males. Of the 79 patients, adult and adolescent populations (80%) were dominant. Jumping from a high bridge (48%) was the most common activity on submersion and accounted for 52% of the high-risk group. The Glasgow coma scale at admission and the cerebral performance scale at discharge showed bimodal patterns. The results of the radiologic studies showed one stable fracture, one suspicious stable fracture, and 18 sprains. The incidence of cervical spine fracture in submerged patients was 2.5% in our study. The incidence of cervical spine injury was higher in the high-risk group than it was in the low-risk group, especially in the jumping-from-high-bridge subgroup; however this observation was not statistically significant. No other factors had any significant effect on the incidence of cervical spine injury. Conclusion: Our study showed that even submerged patients in the high risk group had a low incidence of cervical spine fracture and that the prognosis of a patient did not seem to be influenced by the cervical spine fracture itself.

• 농촌의학ㆍ지역보건
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• 제35권2호
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• pp.124-133
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• 2010

본 연구는 농촌지역 고등학생 299명을 대상으로 2008년 5월에 구조화된 설문지를 이용하여 정신건강, 우울정도 및 인터넷중독 실태를 파악하고, 제변수간의 관계를 파악하여 청소년 정신건강관리 프로그램을 개발하기 위한 기초자료를 제공하기 위해 실시하였다. 그 결과는 다음과 같다. 첫째, 본 연구 대상자의 정신건강 및 문제행동검사(AMPQ) 결과는 비교적 낮은 문제행동을 나타냈으며, 학교유형별 통계적으로 유의하게 차이가 있게 나온 항목은 외재화 문제와 총문제 행동이었으며, 성별에서 남학생이, 외재화 문제군은 남학생에서 더 문제가 있는 것으로 나왔다. 둘째, 우울정도는 비교적 낮은 점수를 나타냈으며, 잠재적 우울군 5.1%, 고위험 우울군 0.3%이었다. 셋째, 인터넷중독정도는 전체적으로 정상군 96.9%, 잠재적 위험군 1.7%, 고위험군 1.4%이었으며, 제변수간에 통계적으로 유의한 차이는 없었다. 넷째, 대상자의 AMPQ와 우울정도 및 인터넷 중독과는 매우 상관성이 있는 것으로 나왔다. 전반적인 정신건강 문제는 우울정도가 심할수록, 인터넷중독이 심할수록 있는 것으로 나왔다. 이상과 같은 결과에서 청소년 정신건강의 심각성을 인식하고 문제가 발생하기 전에 사전예방하고, 조기에 치료할 수 있는 프로그램의 개발과 제도적 장치 마련이 필요하다. 특히 청소년기 우울증은 성인과 달리 발견이 매우 어려우므로, 가장 중요한 것은 조기 발견하여 적절한 관리 및 치료 방향을 설정하는 것이다.

• 한국식생활문화학회지
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• 제29권6호
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• pp.648-658
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• 2014

The aim of this study was to investigate the relationships between eating habits and health among adolescents in Shanghai and Heze, China. A cross-sectional study was conducted in 2013 on 2,089 adolescents; 1,089 students were from Shanghai and 999 students from Heze region. Eating habits, weight, height, and nutritional knowledge were assessed using a self-administered questionnaire. Eating habits score was classified into two categories: healthy eating habits and unhealthy eating habits, based on "Korean Youth Risk Behavior Web-based Survey", for statistical data analysis. Associations between eating habits, BMI, and nutritional knowledge were examined using a general linear model with adjustment of potential confounding factors such as region, gender, age, parents' education level, and pocket money. Statistical analyses were performed using the SAS (version 9.3) program. Proportions of healthy eating habits group were 90.0% for breakfast (3-7 times/wk), 29.1% for fruit (${\geq}once/d$), 12.5% for vegetable (${\geq}3times/d$), 7.3% for milk (${\geq}2times/d$), 90.0% for fast food (<3 times/wk) consumption, respectively. The average BMI score was 20.1 (Shanghai 20.5 Heze 19.6), which is in the range of normal weight. Rates of obesity and overweight were 16.5% and 8.3% in Shanghai and Heze, respectively. There were significant negative correlations between intake frequencies of breakfast, fast food, biscuits, sugar, chocolate, and BMI score. Eating habits and nutritional knowledge score showed a significant positive correlation. These results showed better eating habits regarding eating regularity and consumption of fruits and soft drinks in Chinese adolescents compared with Korean adolescents, although cultural differences were not fully considered. This study demonstrated significant associations of BMI and nutritional knowledge with dietary behavior in Chinese adolescents in two regions of China. Further studies on Chinese adolescents from other regions in China should be considered.

• 한국식품영양과학회지
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• 제21권1호
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• pp.1-8
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• 1992

본 연구는 $16{\sim}18$세의 남자 고등학생 7명을 대상으로 4주간 평상시와 같은 생활양식과 적정 체중을 유지시키면서 에너지 섭취량(GE)과 체내 에너지 보류량(BE)의 변동을 측정하므로서 (에너지 평형법) 에너지 소비량(EE)을 산출하였다. 에너지 섭취량과 대변으로의 에너지 손실량(FE)은 열량계로 측정하였고 소변의 것 (UE)은 질소 배설량으로부터 환산하였다. 지방 조직량(FM)은 피부두께를 측정하여 산출한 신체 밀도법에 의하였다 1) 총 에너지 섭취량에 대한 당질, 단백질 및 지방질의 구성비는 각각 $73.7{\pm}0.3%,\;13.5{\pm}0.3%$ 및 $12.9{\pm}0.5%$이었다. 2) 총 에너지 섭취량에 대한 대변으로의 에너지 손실율은 2.4% 이었다. 3)대변과 소변으로의 에너지 손실량을 감하여 산출한 1일1인당 평균 대사에너지량(ME)은 $2582{\pm}61kcal$이었다. 4) 28일동안의 체성분 변동량으로부터 산출한 체내 총 에너지 변동량(BE)은 평균 $4309{\pm}1837kcal$가 감소되었다. 5) 1일1인당 평균 에너지 소비량은 $2736{\pm}59kcal$로서 체중 kg당 $46{\pm}1kcal$이었다.

• 한국컴퓨터산업학회논문지
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• 제6권3호
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• pp.477-493
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• 2005

식사장애(eating discorder)는 비교적 최근에 와서 관심과 흥미의 대상이 되었는데 최근 20년간 이들의 발생빈도의 증가 자체가 이 질병에 대한 전문적이거나 일반적인 관심의 증가를 가져왔다. 이러한 장애는 마른 것에 대한 지나친 욕망이 특징인 신경성 식욕 부진증(anorexia nervosa)과 살찌는 것에 대한 두려움이 특징인 신경성 대식증(bulima nurvosa)으로 나뉘어 진다. 이들 장애에 대한 역학사는 조사방법 및 대상에 따라 차이가 많으나 일반인에서의 신경성 식욕 부진증의 유병율은 $1.0\%\~4.0\%$정도이며 신경성 대식증은 $2\%$ 정도라고 보고되었고 우리나라에서는 일반 대학생을 대상으로 한 연구에서 신경성 식욕부진증이 $0.7\%$, 거식증이 $0.8\%$라고 보고한 바 있으며 이들은 대부분 식습관이 나쁘거나 식사태도 역시 나쁜 경향이 높다고 시사한 바 있다. <중략> 이에 본 연구에서는 식사장애의 유형들을 알아보고 신체적, 정신적으로 올바른 영양섭취와 성장이라는 중요한 시기에 있는 청소년들을 대상으로 식사장애에 대한 위의 두 가지 대표적인 경우를 혼합적으로 문항을 구성하고 이를 체크하여 언제나 확인할 수 있는 식사장애 자가진단 시스템을 구현해 보고자 한다.

• 한국학교보건학회지
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• 제20권1호
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• pp.91-101
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• 2007

Purpose: The present study intended to reveal the association between the physique of adolescent women and dysmenorrhea, and the factors related to the frequency of dysmenorrhea. Methods: The study subjects included 511 girls of a women's high school in Daejeon city and they were, during the period of March 1st through April 30th, 2005, given self-administered questionnaires about frequency of menstruation, age, physique, exercise, and such menstruation-related items as age of menarche, menstrual period and days, and amount. Results: As with the frequency of dysmenorrhea, 38.4% experienced it 「always」, 44.6% 「occasionally」, and 17.0% 「almost scarcely」, and those with dysmenorrhea accounted for 83.0% of the subjects. The frequency of dysmenorrhea was not significant difference according to the BMI and HPI. However, the lower the age of menarche and the greater the amount of menstrual flow, the more frequent dysmenorrhea. The symptoms of dysmenorrhea included the highest frequency of low back pain(68.5%) and it was followed by abdominal pain(65.9%), sensibility(54.0%), fatigue(51.7%), and nervousness(49.5%). These accompanied symptoms tended to be worse as the frequency of dysmenorrhea increased. The multiple logistic regression analysis revealed that the relative risk of frequency of dysmenorrhea is 2.2 times in age of 14, by a standard age of 15 as menarchial age, 2.2 in 13, and 3.1 in below 12. The menstrual days was 3.0 times in both below 2 days and over 8 days with the standard days of 3-7 days. The menstrual amount was 1.9 times in the group with a greater amount of menstrual bleeding and 1.5 times in the group with a less amount than the normal group, respectively. Conclusion: The above results suggest that the rate of experiencing dysmenorrhea was up to 83.0% and 38.4% from these had dysmenorrhea upon every menstruation. It is thought that dysmenorrhea could be a great disadvantage sufficient to impair optimal health to a larger body of school girls. Further, for quality of life, it is required that more fundamental strategies instead of pain killers or others for palliation of dysmenorrhea would be established among adolescents.

• Nutrition Research and Practice
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• 제17권6호
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• pp.1084-1098
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• 2023

BACKGROUND/OBJECTIVES: Previous research has shown maternal betaine supplementation alleviates fetal-derived hepatic steatosis. Therefore, this study examined the anti-inflammatory effect of maternal betaine intake in offspring mice and its mechanism. MATERIALS/METHODS: Female C57BL/6J mice and their offspring were randomly divided into 3 groups according to the treatment received during gestation and lactation: control diet (CD), fatty liver disease (FLD), and fatty liver disease + 1% betaine (FLD-BET). The FLD group was given a high-fat diet and streptozotocin (HFD + STZ), and the FLD-BET group was treated with HFD + STZ + 1% betaine. After weaning, the offspring mice were given a normal diet for 5 weeks and then dissected to measure the relevant indexes. RESULTS: Compared to the CD group, the offspring mice in the FLD group revealed obvious hepatic steatosis and increased serum levels of alanine aminotransferase, interleukin (IL)-6, and tumor necrosis factor (TNF)-α; maternal betaine supplementation reversed these changes. The hepatic mRNA expression levels of IL-6, IL-18, and Caspase-1 were significantly higher in the FLD group than in the CD group. Maternal betaine supplementation reduced the expression of IL-1β, IL-6, IL-18, and apoptosis-associated speck-like protein containing C-terminal caspase recruitment domain (ASC). Maternal betaine supplementation also reversed the increasing protein expressions of nitric oxide dioxygenase-like receptor family pyrin domain containing 3 (NLRP3), ASC, Caspase-1, IL-1β, and IL-18 in offspring mice exposed to HFD + STZ. Maternal betaine supplementation decreased the homocysteine (Hcy) and s-adenosine homocysteine (SAH) levels significantly in the livers. Furthermore, the hepatic Hcy concentrations showed significant inverse relationships with the mRNA expression of TNF-α, NLRP3, ASC, and IL-18. The hepatic SAH concentration was inversely associated with the IL-1β mRNA expression. CONCLUSIONS: The lipotropic and anti-inflammatory effect of maternal betaine supplementation may be associated with the inhibition of NLRP3 inflammasome in the livers of the offspring mice.