• Journal of Nutrition and Health
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• 제32권4호
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• pp.430-436
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• 1999

This study investigated the correlations among nutrient intakes, and immune status in Korean young women in relation to body mass index(BMI). Subjects were classified as underweight, normal or overweight, with anthropometric measurements of these three groups significatly different in terms of weight, body fat, waist measurement, hip measurement, waist/hip ratio(WHR), and skindfold thickness(p<0.001). Average vitamin A, vitamin B1, vitamin B2, calcium and zinc levles were lower than the Korean RDA. Vitamin A levels were found to be significantly correlated with BMI(p<0.05). There was no significant difference in total T and B lymphocytes or IgG, IgG, and IgM levels with respect to BMI, but Natural Killer(NK) cell levels were found significantly increased with increased BMI(p<0.05). BMI was also positively correlated with iron intake and negatively correlated with vitamin A intake in the normal group. Based upon this study, further research on nutritional, immune and trace-mineral status of overweight and underweight young women is required for better health promotion in this female populaton.

• Molecular & Cellular Toxicology
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• 제3권4호
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• pp.320-325
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• 2007

Promoter hypermethylation of the $p16^{INK4a}$ gene was investigated in 52 sets of samples of tumor tissue and adjacent normal tissue from Korean patients with colorectal cancer, using the proposed modified the Real-time PCR/SYBR Green detection method presented in this study. In normal tissue, 29 of 52 patients (56%) were methylated and in tumor tissue, 23 of 52 patients (44%) were methylated. The 34 cases (65.4%) showed a concordant DNA methylation pattern in both normal tissue and tumor tissue. Analyzing the association between the clinicopathologic features and DNA methylation status of the $p16^{INK4a}$ gene, the DNA methylation status according to by Duke's stage was different while other clinicopathological characteristics, including the age, sex, tumor stage, and histologic type of the patient were not found to be correlated with $p16^{INK4a}$ methylation. With multivariate logistic regression, it was observed that the DNA methylation status of $p16^{INK4a}$ gene in normal tissue was correlated with the DNA methylation status of the $p16^{INK4a}$ gene in tumor tissue (P=0.026). According to a Kaplan-Meier survival analysis, a difference in the survival rate by DNA methylation status was found, but it was not significant.

• 가정∙방문간호학회지
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• 제9권2호
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• pp.69-77
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• 2002

The purpose of this study was to assessment of hospitalized patients. Nutritional assessment was performed on 353 hospitalized patients before TPN support by ideal body weight. albumin, total lymphocyte count, cholesterol. The data analysis were performed on frequency, percentage, means and standard deviation. The major findings as follows: 1. Everage NPO duration was $6.77\pm5.39$day and $\geq5$days 48.9%, >5days 51.1%. NPO duration of 1M, NL, GS, Others prolonged. 2. %IBW was everge $94.86\pm17.21%$ 43.1% normal. 37.8% low weight. There were low weight IM 44.8%. TS 47.8%, Others 44.0%. 3. Albumin was everage $2.93\pm0.51$g/dl. moderate malnutrition 45.4%, mild malnutrition 30.9%. All session were malnutrition status. 4. Total lymphocyte count was ever age $960.41\pm721.32cell/mm^2$. severe malnutrition 43.9%. moderate malnutrition 29.0%, mild malnutrition 24.4%, normal 2.7%. All session were malnutrition status. 5. Cholesterol was everage $123.02\pm45.67$mg/dl 58.4% low level. 41.2% normal. 0.4% high level. 1M, GS and TS were low level. NL, NS, DR, Others were normal. It was very poor nutritional status before TPN support of patients. The malnutrition decrease immunity, slowly cure injury, cause abnormality organs, increase the complication and obstruct the recovery. Therefore, Evaluating and correcting are very important.

• 대한지역사회영양학회지
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• 제7권4호
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• pp.578-584
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• 2002

This study was designed to investigate the association between the period of engraftment and the nutritional status of patient s undergoing bone marrow transplantation for acute myelogenous leukemia (AML). Nutritional status was evaluated by body mass index (BMI), percentage of ideal body weight (PIBW), percentage of weight loss, and serum albumin, total protein (T protein), hemoglobin (HGB) and hematocrit (HCT) levels on the day prior to transplantation and on the day of bone marrow transplantation. The periods of engraftment were determined by absolute neutrophil counts (ANC) above $500/mm^3$ from the day of bone marrow transplantation. The study subjects were 80 patients (55 males, 25 females) with acute myelogenous leukemia admitted to the University Hospital in Seoul. The result of this study is as follows : Tie nutritional status values of the majority of patients on the day prior to transplantation were in the normal range except for HGB and HCT ; however, during hospitalization, all of the levels of the nutritional status values were significantly decreased. The periods of engraftment of the abnormal group according to their BMI, PIBW, HGB and HCT levels on the day of bone marrow transplantation showed no difference when compared to the normal group. However, the periods of engraftment of the abnormal group, according to the percentage of weight loss, albumin, and T protein levels were significantly decreased when compared to the normal group. Therefore, the nutritional status of patients at the time of transplant had a noticeable influence on the periods of engraftment. Our results suggested that nutritional status is a critical factor of engraftment in BMT during pre-transplant and post-transplant. Futhermore, we recommend that the process of nutritional preparation for the transplant should initiate immediately after the transplant decision has been made.

• 한국식생활문화학회지
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• 제25권2호
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• pp.170-178
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• 2010

We conducted this study to determine the factors associated with childhood obesity. The subjects were 170 preschool children in Busan. Data were collected by using questionnaires which asked for information about socioeconomic status, parental perception of their child's weight status and dietary/physical activity behavior. BMI was calculated for each child and their classification was determined, according to their age and sex, as follows: "overweight" at or above the 85th percentile, "normal" for the 15th-85th percentile, and with a BMI below the 15th percentile the children were deemed as underweight. Classification according to BMI percentile showed that 23.5% ($18.25{\pm}1.33\;kg/m^2$) of the children were overweight, 62.9% ($15.51{\pm}0.76\;kg/m^2$) normal, and 13.5% ($13.23{\pm}2.86\;kg/m^2$) were underweight. Socioeconomic status, as represented by the parents' level of education, the occupation of the father and the household income, did not affect the results. However, mothers working outside the household was a factor that was more likely to affect the weight status (p<0.05). Among mothers whose children were overweight, 30% underestimated their children's weight status (believing them to be of normal weight when they were overweight), and 25% failed to recognize the necessity of weight control for their overweight children. While sedentary activity and total daily activity levels were not related to BMI, the level of physically active leisure activity was inversely correlated with BMI (p<0.05). Although there were no differences in total energy intake, dietary behavior was significantly related to weight status. Overweight children had poor eating tendancies: they eat faster (in less than 15 minutes), overeat, and eat late at night. Based on our findings where hereby recommended the following interventions to help limit weight problems in Korean pre-schoolers: early promotion of active leisure behavior and healthy eating habits, along with attempting to correct parental misperception of healthy weight status for children.

• 한국수산과학회지
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• 제29권6호
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• pp.828-836
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• 1996

The histological changes of gill, liver, spleen and muscle, and respiration and blood variables and liver glycogen content were examined in black seabream, Acanthopagrus schlegeli. Fish were exposed to a high level of total ammonia nitrogen (10.4 mg/l) and recovered from exposure $(0.4{\pm}0.2mg/l)$ in a closed recirculating seawater system. In the process of exposure, mortality was $9\%$, and hyperplasia, necrosis or inflammation appeared in all tissues except for muscle. Oxygen consumption was decreased by $49\%$, and red blood cell (RBC) number, hematocrit and hemoglobin concentration were significantly decreased, while plasma glucose contents, activities of glutamate-oxaloacetate transaminase (GOT) and glutamate-pyruvate transaminase (GPT) increased. Liver glycogen content significantly increased from $6.6\%\;to\;10.4\%$. A large amount of hemosiderin was observed in the splenic tissue. During the recovery period, RBC number, hematocrit, hemoglobin concentration, GOT and GPT activities were returned to the normal status. Histological status of liver tissue was returned to the normal, but liver glycogen content was not recovered. During the recovery period, spleen melanin-macrophages temporarily increased, but subsequently decreased to the normal status.

• 기본간호학회지
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• 제22권4호
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• pp.387-397
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• 2015

Purpose: This study aimed to evaluate nutritional status and fatigue, and to identify the relationship between nutritional status and fatigue in gynecological cancer patients receiving chemotherapy. Methods: Participants were 106 outpatients who had uterine, ovary, or breast cancer and a descriptive cross-sectional design was used. Nutritional indicators including biochemical and anthropometric measures, the Subjective Global Assessment (SGA) scale, and the Piper's Revised Fatigue Scale were completed. Results: About thirty-nine percent of the patients were malnourished based on the SGA. Serum hemoglobin and total lymphocyte levels were less than the normal ranges, although anthropometrics were normal. The women experienced moderate fatigue with a mean score of $5.84{\pm}2.00$. Nutritional status was significantly different by age, education, employment status, and monthly income. The women also had different nutritional status and fatigue depending on the type of cancer and chemotherapy. Fatigue was significantly related to SGA scores, serum hemoglobin, triceps skinfold thickness and mid-arm muscle circumference. Conclusion: The results of this study highlight an urgent need to provide adequate nutritional support and fatigue management with individualized strategies for gynecological cancer patients on chemotherapy.

• 대한지역사회영양학회지
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• 제3권4호
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• pp.565-573
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• 1998

Iron deficiency anemia in pregnant women has been of great concern because of its negative effects on the outcomes of pregnancy. Much of evidence has shown that there are associations between pregnancy outcomes and maternal iron status. Maternal iron status might affect pregnancy outcomes through the iron status of the cord blood. In this study, we divided 91 subjects into two groups : the anemic and the normal groups. The groups were classified according to their hemoglobin(Hb) and hematocrit(Hct) values of the maternal blood in the third trimester of the pregnancies. We determined the parameters for the iron status of the cord blood and then analyzed the correlations between these parameters and the pregnancy outcomes. Mothers in the anemic group had a significantly higher parity number and a lower dietary score as well as a shorter duration of iron supplements consumed compared to those in the normal group. Maternal Hb values in the third trimester had positive correlations with the infant's head and chest circumferences, and the Hct values related positively to the infant's chest circumferences. On the other hand, Hb concentrations of the cord blood had positive correlations with the infant's height and head and chest circumferences. The Hct values of the cord blood had positive correlations with gestational periods and the cord lengths. These results suggest that the maternal iron status might influence fetal development through the iron status of the cord blood.

• 동아시아식생활학회지
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• 제27권2호
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• pp.104-113
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• 2017

The purpose of this study was to analyze and consumption patterns diet/low-calorie food. Ubjects were 353 adult women aged 20s~50s. Ubjects were divided into three groups according to body mass index (BMI): Normal group (BMI>23.0), overweight group (23.0${\leq}$BMI<25.0), and obesity group (BMI${\geq}$25.0). This study collected all information by self-administrated questionnaires. The SPSS version 21.0 was used for analysis of data. The obesity group lower education level (p<0.001), higher age (p<0.001) and higher income (p<0.001) than normal group. However, score of health status was highest in normal group (p<0.001). Proportion of obesity group pill type diet/low-calorie (p<0.034), drug (diuretic, appetite suppressant and riental medicine) (p<0.001), and cosmetic surgery (p<0.001). The main reason for consumption of diet/low-calorie was control without starving (28.0%). Obese group emphasized manufacturer, ingredient and reputation, whereas the normal group emphasized price and expected effectiveness (p<0.001).

• 대한지역사회영양학회지
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• 제6권3호
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• pp.297-305
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• 2001

The aim of this study was to investigate the effects of food behavior and life-style behavior on the health-status of male industrial workers in the Masan region. The average age of the 173 male subjects was 42.9 years and 59% of the subjects were labor workers, 25% office workers, and 70% of them earned 1 - 1.5 million won monthly. The subjects were categorized into one of three groups : normal group, health-concerned group, and disease-suspected group classified by the criteria of the data (blood pressure, blood glucose, blood hemoglobin, serum total cholesterol, and serum triglyceride) obtained from a health examination. Forty seven belonged to the normal group, 71 to the health-concerned group, and 55 to the disease-suspected group. The health-concerned group, and disease-suspected group had significantly higher systolic and diastolic blood pressure, blood glucose, and serum total cholesterol than the normal group, and the disease-suspected group showed a significantly higher serum triglyceride level than the normal and health-concerned groups. The disease-suspected group consumed carbohydrate foods, such as cereals more frequently and protein foods such as beans and eggs less frequently than the normal group and health-concerned group. However, there was no difference in nutrient intakes among the three groups. The disease-suspected group and health-concerned group smoked more cigarettes and drank more frequently than the normal group, and the disease-suspected group exercised less as compared to the normal group. The kinds of diseases diagnosed in the disease-suspected group were hypertension, hyperlipidemia, liver disease, and neurological disease. The results of this study indicate that nutrition education and monitoring should be implemented for industrial workers to prevent chronic diseases and to reduce medical cost for the treatment of disease.