• 한국축산식품학회지
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• 제38권1호
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• pp.52-63
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• 2018

Cheese consumption has been gradually increased in China. However, both the manufacturing process of cheese and the utilization of its main by-product were not well developed. Based on the sensory evaluation, Box-Behnken Design (BBD) was performed in the present study to optimize the cheese processing, which was proved more suitable for Chinese. The optimal parameters were: rennet 0.052 g/L, start culture 0.025 g/L and $CaCl_2$ 0.1 g/L. The composition analysis of fresh bovine milk and whey showed that whey contained most of the soluble nutrients of milk, which indicated that whey was a potential resource of cyclic adenosine-3', 5'-monophosphate (cAMP). Thus, the cAMP was isolated from whey, the results of high-performance liquid chromatography (HPLC) analysis showed that the macroporous adsorption resins (MAR) D290 could increase the concentration of cAMP from $0.058{\mu}mol/mL$ to $0.095{\mu}mol/mL$. We firstly purified the cAMP from the whey, which could become a new source of cAMP.

• Journal of Nutrition and Health
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• 제32권7호
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• pp.767-774
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• 1999

This study was carrid out to examine a part of the mechanism for the etiology of diabetic complications. Thirty normal and forty streptozotocin(STZ)-induced diabetic rats were used as the animal models. Animals were sacrificed at the time points of 3 days, 1, 2, 4 and 6 weeks after STZ-injection and time course in body weight and organ weight, the levels of blood glucose, plasma lipid patterns, and atherogenic index were measured during 6 weeks. The STZ-diabetic animals showed 63% survival rate and fsting blood glucose levels of the diabetic animals measured in the range of 230-410mg/dL during the experimental period. The body weigh of diabetic animals decreased significantly throughout the experimental period and the relative weights of organs to body weight were significantly higher than the normal control ones. The enlargement of the kidney in the diabetic animals was especially remarkable. Plasma triglyceride concentration in diabetic rats substancially increased from the first week of onset of diabetes mellitus and maintained higher levels than the control ones throughout the whole experimental period. The plasma total cholesterol level and atherogenic index in the diabetic rats were significantly higher than the normal ones from the third day after STZ injection and showed a gradual increase with the duration of the disease. Throughout the experiment, the diabetic rats consistently showed a slightly lower HDL-cholesterol level compared to the normal animals. From the results of this study, it appears that the significant changes in blood lipid pattern in STZ-diabetic animals start from the first week after STZ injection.

• 한국마이크로전자및패키징학회:학술대회논문집
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• 한국마이크로전자및패키징학회 2004년도 ISMP Pb-free solders and the PCB technologies related to Pb-free solders
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• pp.257-261
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• 2004

Recently, Pb free solder technologies are developed, and start using for many packaging items. But this technology contains many problems. They are very high re-flow temperature and high cost than normal solder paste. Specially, high re-flow temperature effects heavy damage to packaging and occur many crack to packaging. We developed special ACI (anisotropic conductive ink) that becomes substitution of solder paste. This technology cans adhesive lower temperature such as $120\~150^{\circ}C$. Adhesion time is very short, too. This technology is suitable for mass production.

• Wind and Structures
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• 제17권6호
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• pp.671-680
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• 2013

Static aeroelastic is investigated in a wind turbine blade. Imposed to different loadings, the very long and flexible structures of blades experience some changes in its preliminary geometry. This results in variations of aerodynamic loadings. An iterative approach is developed to study the interactions between structure and aerodynamics evaluating variations in induced stresses in presence of aeroelasticity phenomenon for a specific wind turbine blade. A 3D finite element model of the blade is constructed. Aerodynamic loading is applied to the model and deflected shape is extracted. Then, aerodynamic loadings are updated in accordance with the new geometry of the deflected blade. This process is repeated till the convergence is met. Different operational conditions consisting of stand-by, start-up, power production and normal shut-down events are investigated. It is revealed that stress components vary significantly in the event of power production at the rated wind speed; while it is less pronounced for the events of normal shut-down and stand-by.

• 제어로봇시스템학회논문지
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• 제12권11호
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• pp.1088-1094
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• 2006

In this paper, an auto path generation and an active compliance grinding control using 3-axis farce sensor are presented. These control algorithms enable the grinding robot to follow unknown path of various workpiece shape pattern. The robot is able to go grinding along unknown paths by position controller managing tangential direction angle and cutting speed, with only information about the start position and the end position. Magnitude and direction of normal force are calculated using force data that go through low pass filter. Moreover, normal and tangential directions are separated for force control and velocity control, respectively.

• Journal of Korean Neurosurgical Society
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• 제62권3호
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• pp.265-271
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• 2019

The expansion and folding of the cerebral cortex occur during brain development and are critical factors that influence cognitive ability and sensorimotor skills. The disruption of cortical growth and folding may cause neurological disorders, resulting in severe intellectual disability and intractable epilepsy in humans. Therefore, understanding the mechanism that regulates cortical growth and folding will be crucial in deciphering the key steps of brain development and finding new therapeutic targets for the congenital anomalies of the cerebral cortex. This review will start with a brief introduction describing the anatomy of the brain cortex, followed by a description of our understanding of the proliferation, differentiation, and migration of neural progenitors and important genes and molecules that are involved in these processes. Finally, various types of disorders that develop due to malformation of the cerebral cortex will be discussed.

• Asian-Australasian Journal of Animal Sciences
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• 제28권8호
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• pp.1187-1193
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• 2015

This study determined the effects of dietary restriction on growth and the expression of lipid metabolism and growth hormone signaling genes in the longissimus dorsi muscle (LM) of Korean cattle. Thirty-one Korean cattle steers (average age 10.5 months) were allocated to normal (N; n = 16) or dietary restriction (DR; n = 15) groups. The feeding trial consisted of two stages: for the 8-month growing period, the DR group was fed 80% of the food intake of the normal diet, and for the 6-month growth-finishing period, the DR group was fed a DR total mixed ration with 78.4% of the crude protein and 64% of the net energy for gain of the normal diet. The LM was biopsied 5 months (period 1 [P1] at 15.5 months of age) and 14 months (period 2 [P2] at 24.5 months of age) after the start of feeding. The mRNA levels were determined using real-time polymerase chain reaction. Body weight, daily feed intake, average daily gain, and feed efficiency were lower in the DR group compared with the normal group at both P1 and P2. At P1, the lipogenic fatty acid synthase (FASN) mRNA levels were lower (p<0.05) in the DR group compared with the normal group. The DR group tended (p = 0.06) to have higher of levels of growth hormone receptor (GHR) mRNA than the normal group. At P2, the DR group tended to have lower (p = 0.06) androgen receptor (AR) mRNA levels than the normal group. In conclusion, our results demonstrate that dietary restriction partially decreases the transcription of lipogenic FASN and growth hormone signaling AR genes, but increases transcription of the GHR gene. These changes in gene transcription might affect body fat accumulation and the growth of the animals.

• 한국추진공학회지
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• 제4권2호
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• pp.6-11
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• 2000

고압의 불활성 기체를 이용하여 엔진에 추진제를 공급하는 액체로켓의 경우, 추진제 탱크의 압력은 정상연소상태의 연소압을 기준으로 하여 설계한다. 그러나 연소초기의 연소실 압력은 대기압 상태이므로 과도한 유량이 공급되어 이로 인해 hard-start가 발생하며, 최악의 경우 엔진의 파손을 가져온다. 본 연구에서는 이러한 문제를 해결하고 안정된 연소를 위하여 개선된 추진제 공급시스템을 제안하며, 이는 실제 연소실험을 통해 그 성능을 규명하였다. 이 공급시스템은 연소초기의 급격한 연소실압의 상승을 막기 위하여 추진제를 예연소단계와 주연소단계의 2단계로 공급하며, 연소초기 및 연소 중의 일정한 유량공급을 위해 Cavitating Venturi를 사용하는 시스템이다. 설계 유량보다 적은 양의 추진제를 먼저 공급하여 연소압이 일정수준에 달하도록 예연소압을 형성하게 하는 방법이다. 또한, Cavitating Venturi는 오직 공급압에 의해서만 유량이 결정되며, 출구 압에 영향을 받지 않으므로 연소초기는 물론이고, 연소 중 이상연소에 의해 연소압이 떨어져도 설계치 이상의 유량이 공급되지 않는다.

• 대한불안의학회지
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• 제10권1호
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• pp.37-43
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• 2014

Objective : Social Phobia is associated with extensive disability and reduced quality of life. The concept of 'social self' is a representation of the self-reflected in the eyes of others, and is recruited during self-face recognition, which is closely related to self-esteem. The aim of this study was to identify the relationship of face recognition for self and others using measures of social anxiety and self-esteem in patients with social phobia. Methods : Twenty-seven patients with social phobia and twenty-three normal controls were evaluated with scales of self-esteem, depression, anxiety and other psychiatric symptoms. All participants completed the self-face recognition task. Nine self-faces, nine other faces and eighty-one morphed faces were presented randomly for each trial. The participants were instructed to make a decision as to whether the stimuli were self-face or not. The responses and reaction times were recorded during the task. Results : There were no group differences of the morphing composition at the recognition start point as self-face. In patients with social phobia, the mean reaction time at the start point of recognizing as a self-face was 1,037.6 ms, which was significantly longer than that of normal controls (911.3 ms, p<0.05). Patients with social phobia showed a significant negative correlation between the mean reaction time and the severity of depression when the stimuli were recognized as a self-face (r=-0.421, p<0.05). Conclusion : A difficulty in attention rather than avoidance may be an important factor of face recognition in patients with social phobia. When considering self-face recognition in such patients, many factors, such as anxiety, depression, working memory and theory of mind, need to be considered.

• 한국항공우주학회지
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• 제30권1호
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• pp.88-94
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• 2002

고압의 불활성 기체를 이용하여 엔진에 추진제를 공급하는 액체로켓의 경우, 추진제 탱크의 압력은 정상연소상태의 연소압을 기준으로 하여 설계한다. 그러나 연소초기의 연소실 압력은 대기압 상태이므로 과도한 유량이 공급되어 이로 인해 hard-start가 발생하며, 최악의 경우 엔진의 파손을 가져온다. 본 연구에서는 이러한 문제를 해결하고 안정된 연소를 위하여 개선된 추진제 공급시스템을 제안하며, 이는 실제 연소실험을 통해 그 성능을 규명 하였다. 이 공습시스템은 연소 초기 및 연소 중의 일정한 유량공급을 위해 Cavitating Venturi를 사용하는 시스템이다. Cavitating Venturi는 오직 공급압력에 의해서만 유량이 결정되며, 출구압력에 영향을 받지 않으므로 연소 초기는 물론이고, 연소 중 이상 연소에 의해 연소압이 떨어져도 설계치 이상의 유량이 공급되지 않는다. 본 실험을 통해서 Cavitating Venturi의 설계 영역에서의 유량에 대한 안정성이 입증되었기 때문에, Cavitating Venturi는 액체로켓 이외의 압력강하량 변화가 큰 시스템에서 매우 효과적일 것이다.