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In vivo Investigation of Anti-diabetic Properties of Ripe Onion Juice in Normal and Streptozotocin-induced Diabetic Rats

  • Lee, Chul-Won;Lee, Hyung-Seok;Cha, Yong-Jun;Joo, Woo-Hong;Kang, Dae-Ook;Moon, Ja-Young
    • Preventive Nutrition and Food Science
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    • v.18 no.3
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    • pp.169-174
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    • 2013
  • The acute and subacute hypoglycemic and antihyperglycemic effects of drinkable ripe onion juice (Commercial product name is "Black Onion Extract") were investigated in normal and streptozotocin-induced diabetic rats. For tests of acute and subacute hypoglycemic effects, ripe onion juice (5 and 15 mL/kg b.w.) was administered by oral gavage to normal Sprague Dawley rats and measurements of fasting glucose levels and oral glucose tolerance tests were performed. Tolbutamide was used as a reference drug at a single oral dose of 250 mg/kg b.w. To test anti-hyperglycemic activity, the ripe onion juice was administered to streptozotocin-induced diabetic rats by oral gavage at single dose of 15 mL/kg b.w. per day for 7 consecutive days. Oral administration of the ripe onion juice at either dosed level of 5 or 15 mL/kg b.w. showed no remarkable acute hypoglycemic effect in normal rats. The two dosed levels caused a relatively small reduction, only 18% and 12% (5 and 15 mL/kg b.w., respectively) decrease in glucose levels at 2 h after glucose loading in normal rats. However, at 3 h after glucose loading, blood glucose levels in the ripe onion juice-dosed rats were decreased to the corresponding blood glucose level in tolbutamide-dosed rats. Although showing weak hypoglycemic potential compared to that of tolbutamide, oral administration of ripe onion juice (15 mL/kg b.w.) for a short period (8 days) resulted in a slight reduction in the blood glucose levels that had elevated in Streptozotocin-induced diabetic rats. In conclusion, these results suggest that the commercial product "Black Onion Extract" may possess antihyperglycemic potential in diabetes.

Structural integrity of KJRR-F fresh nuclear fuel under vehicle-induced vibration for normal transport condition

  • Jeong, Gil-Eon;Yang, Yun-Young;Bang, Kyoung-Sik
    • Nuclear Engineering and Technology
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    • v.54 no.4
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    • pp.1355-1362
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    • 2022
  • Nuclear fuel, including its fresh state, must be handled safely due to its critical and hazardous nature. Under normal transport conditions, several interactions take place among different components, such as transport cask used for loading the nuclear fuel and tie-down structure to attach with the vehicle. To ensure structural integrity of the nuclear fuel, vibrations and impacts transmitted from the vehicle must be sufficiently reduced. Therefore, in this study, we conducted two transportation tests from Daejeon to Kijang in Korea to verify the vehicle-induced vibrational characteristics of the KJRR-F fresh nuclear fuel when transported under normal transport conditions. The speed and location of the vehicle were obtained via GPS, and the accelerations between the vehicle and the KJRR-F fresh nuclear fuel were measured. Additionally, using the acceleration results, a structural analysis was conducted to confirm the structural integrity of the nuclear fuel under the most severe conditions during normal transport.

Behavior of Segmented Composites Using General Mortar under Static and Impact Loading (일반 모르타르를 이용한 분절 복합체의 정하중 및 충격하중 실험)

  • Kim, Youl-Hee;Min, Kyung-Hwan;Lee, Jae-Seong;Yoon, Young-Soo
    • Proceedings of the Korea Concrete Institute Conference
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    • 2008.11a
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    • pp.33-36
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    • 2008
  • It is generally known that a shell in the form of layered structures stacked up thin elements by organic adhesives has high resistance capacity against static and impact loading. The complex materials such as these diversified layered structures are more reliable and efficient to the impact loading than the single material. In this study, the segmented composites in the shape of a beam were made, using mortar and concrete block and tested under static and impact loading in order to develop the complex materials in the form of layered structures as the segmented composites to resist impact loading. And it compared to the normal concrete beams having the same compressive strength to evaluate the differences in their performance and failure modes.

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Measurement of Unsteady Loading Noise from Hovering Rotor with Partially Inclined Ground (국부적으로 기울어진 지면을 고려한 제자리비행 로터의 비정상 하중 소음 측정)

  • Jang, Ji-Sung;Lee, Yong-Woo;Lee, Duck-Joo
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2008.04a
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    • pp.140-143
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    • 2008
  • Experiments are performed to consider the ground effects on unsteady loading and acoustic generation. Partially inclined plate is used to maximize the unsteadiness of the rotor. Indirect method to recognize the unsteady effect is used by measuring the noise in the normal direction from the rotor plane. The experiment is conducted with a square plate of about $9m^2$ and one half of the plate is placed parallel with the rotor plane and the other half is inclined. The height of the plate and the angle of the inclined plate can be changed. Helicopter noise is also measured at the 4 different positions to study the directivity of the rotor noise. The distance between microphone and rotor hub is 1.3m. Tonal noise and broad band noise are measured and analyzed. Thickness noise, steady loading noise and unsteady loading noise are investigated from the rotor noise measurement.

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Finite element analysis of RC walls with different geometries under impact loading

  • Husem, Metin;Cosgun, Suleyman I.;Sesli, Hasan
    • Computers and Concrete
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    • v.21 no.5
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    • pp.583-592
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    • 2018
  • Today, buildings are exposed to the effects such as explosion and impact loads. Usually, explosion and impact loads that act on the buildings such as nuclear power plants, airports, defense industry and military facilities, can occur occasionally on the normal buildings because of some reasons like drop weight impacts, natural gas system explosions, and terrorist attacks. Therefore, it has become important to examine the behavior of reinforced concrete (RC) structures under impact loading. Development of computational mechanics has facilitated the modeling of such load conditions. In this study, three kinds of RC walls that have different geometric forms (square, ellipse, and circle) and used in guardhouses with same usage area were modeled with Abaqus finite element software. The three configurations were subjected to the same impact energy to determine the geometric form that gives the best behavior under the impact loading. As a result of the analyses, the transverse impact forces and failure modes of RC walls under impact loading were obtained. Circular formed (CF) reinforced concrete wall which has same impact resistance in each direction had more advantages. Nonetheless, in the case of the impact loading occurring in the major axis direction of the ellipse (EF-1), the elliptical formed reinforced concrete wall has higher impact resistance.

Prediction of Thickness and Loading Noise from Aircraft Propeller (항공기용 프로펠러에서의 두께 및 하중소음 예측)

  • Ryu, Ki-Wahn
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.33 no.2
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    • pp.39-45
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    • 2005
  • The aim of this research is to predict the thickness and loading noise of the round-tip shaped Hartzell propeller currently used in the general aviation aircraft. Before implementing the noise analysis, the pressure distribution on the propeller was obtained by using the free wake panel method and unsteady Bernoulli's equation. The noise signal at observer position can be obtained by using the FW-H equation. The noise prediction results for the propeller indicates that the thickness noise has s symmetric directivity pattern with respect to the tip path plane, while the noise due to loading shows higher noise directivity toward downstream than the upstream direction from the rotor plane. The loading noise is dominant rather than the thickness noise in normal operating condition.

Experimental training of shape memory alloy fibres under combined thermomechanical loading

  • Shinde, Digamber;Katariya, Pankaj V;Mehar, Kulmani;Khan, Md. Rajik;Panda, Subrata K;Pandey, Harsh K
    • Structural Engineering and Mechanics
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    • v.68 no.5
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    • pp.519-526
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    • 2018
  • In this article, experimental training of the commercial available shape memory alloy fibre (SMA) fibre under the combined thermomechanical loading is reported. SMA has the ability to sense a small change in temperature (${\geq}10^{\circ}C$) and activated under the external loading and results in shape change. The thermomechanical characteristics of SMA at different temperature and mechanical loading are obtained through an own lab-scale experimental setup. The analysis is conducted for two types of the medium using the liquid nitrogen (cold cycle) and the hot water (heat cycle). The experimental data indicate that SMA act as a normal wire for Martensite phase and activated behavior i.e., regain the original shape during the Austenite phase only. To improve the confidence of such kind of behavior has been verified by inspecting the composition of the wire. The study reveals interesting conclusion i.e., while SMA deviates from the equiatomic structure or consist of foreign materials (carbon and oxygen) except nickel and titanium may affect the phase transformation temperature which shifted the activation phase temperature. Also, the grain structure distortion of SMA wire has been examined via the scanning electron microscope after the thermomechanical cycle loading and discussed in details.

Pressure loading, end- shortening and through- thickness shearing effects on geometrically nonlinear response of composite laminated plates using higher order finite strip method

  • Sherafat, Mohammad H.;Ghannadpour, Seyyed Amir M.;Ovesy, Hamid R.
    • Structural Engineering and Mechanics
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    • v.45 no.5
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    • pp.677-691
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    • 2013
  • A semi-analytical finite strip method is developed for analyzing the post-buckling behavior of rectangular composite laminated plates of arbitrary lay-up subjected to progressive end-shortening in their plane and to normal pressure loading. In this method, all the displacements are postulated by the appropriate harmonic shape functions in the longitudinal direction and polynomial interpolation functions in the transverse direction. Thin or thick plates are assumed and correspondingly the Classical Plate Theory (CPT) or Higher Order Plate Theory (HOPT) is applied. The in-plane transverse deflection is allowed at the loaded ends of the plate, whilst the same deflection at the unloaded edges is either allowed to occur or completely restrained. Geometric non-linearity is introduced in the strain-displacement equations in the manner of the von-Karman assumptions. The formulations of the finite strip methods are based on the concept of the principle of the minimum potential energy. The Newton-Raphson method is used to solve the non-linear equilibrium equations. A number of applications involving isotropic plates, symmetric and unsymmetric cross-ply laminates are described to investigate the through-thickness shearing effects as well as the effect of pressure loading, end-shortening and boundary conditions. The study of the results has revealed that the response of the composite laminated plates is particularly influenced by the application of the Higher Order Plate Theory (HOPT) and normal pressure loading. In the relatively thick plates, the HOPT results have more accuracy than CPT.

Force-Deformation Characteristics of the Fruit Flesh (과실(果實)의 힘-변형(變形) 특성(特性))

  • Kim, M.S.;Park, J.M.;Choi, D.S.
    • Journal of Biosystems Engineering
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    • v.17 no.2
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    • pp.156-170
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    • 1992
  • The force-deformation relationship gives the basic physical properties of the fruits such as the bioyield point, the rupture point, and the deformations at the bioyield point and the rupture point. These informations are very important to study the stress-strain relationships of the fruits. This study was conducted to analyze those physical properties according to the sampling position of the fruits, and to determine the bioyield point, the rupture point, and the deformations at the bioyield point and the rupture point of the fruits for two different storage conditions(low temperature and normal temperature) and the storage period, and to investigate the effect of loading rate on those physical properties, the hysteresis on the loading-unloading condition and the degree of elasticity of the fruits. The results of the study were as follows : 1. The physical properties(BS, US, BD, and RD) of the test specimen selected from the different sampling positions were quite different. The values of the physical properties were shown smallest ones at the cheek of the fruits, and the statistical test results of the physical properties between the cheek from the other two positions of the fruits showed that there were significant difference at the 1 % level between them. 2. The effect of loading rate on the physical properties of the fruits was relatively large, all the considered physical propertis of the fruits increased with the loading rate, but the hysteresis loss decreased with it. 3. The physical properties of the fruits according to the storage conditions and period showed different, and the bioyield deformation and the rupture deformation of the fruits increased with the storage period, but the bioyield strength and the ultimate strength of the fruits decreased with it. The effect of the storage conditions on the those physical properties showed that the normal temperature storage condition was a little higher than the low temperature storage condition. 4. As a whole, it was shown that the bioyield strength and the ultimate strength of the pear decreased a little faster than those of the apple, and the bioyield deformation and rupture deformation of the pear increased a little faster than those of apple at the two storage conditions.

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Strength Evaluation of Reinforced Concrete Corbels using Nonlinear Strut-Tie Model Approach (비선형 스트럿-타이 모델 방법에 의한 철근콘크리트 코벨의 강도 평가)

  • 윤영묵;신용목
    • Proceedings of the Korea Concrete Institute Conference
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    • 2003.05a
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    • pp.391-396
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    • 2003
  • The concrete corbels consist of various failure mechanisms such as the yielding of the tension reinforcement, the crushing or splitting from compression concrete struts, and localized bearing or shearing failure under the loading plate. However, predicting those failure mechanisms is very difficult. In this study, the ACI 318-02, the softened strut-tie model approach, and the nonlinear strut-tie model approach are applied to ultimate strength analysis of normal strength concrete corbels tested to failure. From the result of the analysis, an effective analysis and design method of normal strength concrete corbels is suggested.

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