• Title/Summary/Keyword: Nonparametric statistical methods

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Effects of aerobic and combined exercise on body composition and blood lipid in the middle-aged women (운동형태에 따른 중년여성의 신체구성과 혈중지질의 변화)

  • Kim, Yong Cheol;Kim, Young Soo;Yang, Jeong Ok;Lee, Bom Jin;Lee, Joong Sook
    • Journal of the Korean Data and Information Science Society
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    • v.24 no.6
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    • pp.1241-1251
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    • 2013
  • The purpose of this study was to investigate and compare the effects of aerobic and complex exercise on body composition and blood lipids in the middle-aged women. Sixteen women whose ages ranged in 40 to 50 years were included in the sample of the study. The sample was divided into two groups: (a) aerobic exercise group (n = 8) and (b) combined exercise training group (n = 8). The aerobic exercise program consisted of bicycle ergometer, stepper, and treadmill, whereas; the combined exercise program was designed to improve muscular strength and aerobic capacity. Both programs took place 4 times a week for 12 weeks with the gradual increase of intensity (HRmax 60% 75% and 1 RM 60% 80%). Data were analyzed by nonparametric methods for pre-post within group mean differences (Wilcoxon signed rank test) and for between group mean differences (Wilcoxon rank sum test). Results indicated that there were statistically significant differences in BMI, body fat mass, and triglyceride within the sample of combined exercise; whereas, no significance existed in any variables within the aerobic exercise group. Results also revealed that statistical significance did exist in body fat mass between the combined and aerobic exercise group. These results implies that the combined exercise may be superior to aerobic only excercise for the body composition and blood lipid of the middle-aged women.

A COMPARATIVE STUDY OF THE 1-PIECE AND 2-PIECE CONICAL ABUTMENT JOINT: THE STRENGTH AND THE FATIGUE RESISTANCE

  • Kwon, Taek-Ka;Yang, Jae-Ho;Kim, Sung-Hun;Han, Jung-Suk;Lee, Jai-Bong
    • The Journal of Korean Academy of Prosthodontics
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    • v.45 no.6
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    • pp.780-786
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    • 2007
  • Statement of problem. The performance and maintenance of implant-supported prostheses are primarily dependent upon load transmission both at the bone-to-implant interface and within the implant-abutment-prosthesis complex. The design of the interface between components has been shown to have a profound influence on the stability of screw joints. Purpose. The Purpose of this study was to compare the strength and the fatigue resistance of 1-piece and 2-piece abutment connected to oral implant, utilizing an internal conical interface. Material and methods. Twenty $Implatium^{(R)}$ tapered implants were embedded to the top of the fixture in acrylic resin blocks. Ten $Combi^{(R)}$(1-piece) and $Dual^{(R)}$(2-piece) abutments of the same dimension were assembled to the implant, respectively. The assembled units were mounted in a testing machine. A load was applied perpendicular to the long axis of the assemblies and the loading points was at the distance of 7mm from the block surface. Half of 1-piece and 2-piece abutment-implant units were tested for the evaluation of the bending strength, and the others were cyclically loaded for the evaluation of the fatigue resistance until plastic deformation occurred. Nonparametric statistical analysis was performed for the results. Results. Mean plastic and maximum bending moment were $1,900{\pm}18Nmm,\;3,609{\pm}106Nmm$ for the 1-piece abutment, and $1,250{\pm}31Nmm,\;2,688{\pm}166Nmm$ for the 2-piece abutment, respectively. Mean cycles and standard deviation when implant-abutment joint showed a first plastic deformation were $238,610{\pm}44,891$. cycles for the 1-piece abutment and $9,476{\pm}3,541$ cycles for the 2-piece abutment. A 1-piece abutment showed significantly higher value than a 2-piece abutment in the first plastic bending moment (p<.05), maximum bending moment (p<.05) and fatigue strength (p<.05). Conclusion. Both 1-piece and 2-piece conical abutment had high strength and fatigue resistance and this suggests long-term durability without mechanical complication. However, the 1-piece conical abutment was more stable than the 2-piece conical abutment in the strength and the fatigue resistance.

Investigation of light stimulated mouse brain activation in high magnetic field fMRI using image segmentation methods

  • Kim, Wook;Woo, Sang-Keun;Kang, Joo Hyun;Lim, Sang Moo
    • Journal of the Korea Society of Computer and Information
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    • v.21 no.12
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    • pp.11-18
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    • 2016
  • Magnetic resonance image (MRI) is widely used in brain research field and medical image. Especially, non-invasive brain activation acquired image technique, which is functional magnetic resonance image (fMRI) is used in brain study. In this study, we investigate brain activation occurred by LED light stimulation. For investigate of brain activation in experimental small animal, we used high magnetic field 9.4T MRI. Experimental small animal is Balb/c mouse, method of fMRI is using echo planar image (EPI). EPI method spend more less time than any other MRI method. For this reason, however, EPI data has low contrast. Due to the low contrast, image pre-processing is very hard and inaccuracy. In this study, we planned the study protocol, which is called block design in fMRI research field. The block designed has 8 LED light stimulation session and 8 rest session. All block is consist of 6 EPI images and acquired 1 slice of EPI image is 16 second. During the light session, we occurred LED light stimulation for 1 minutes 36 seconds. During the rest session, we do not occurred light stimulation and remain the light off state for 1 minutes 36 seconds. This session repeat the all over the EPI scan time, so the total spend time of EPI scan has almost 26 minutes. After acquired EPI data, we performed the analysis of this image data. In this study, we analysis of EPI data using statistical parametric map (SPM) software and performed image pre-processing such as realignment, co-registration, normalization, smoothing of EPI data. The pre-processing of fMRI data have to segmented using this software. However this method has 3 different method which is Gaussian nonparametric, warped modulate, and tissue probability map. In this study we performed the this 3 different method and compared how they can change the result of fMRI analysis results. The result of this study show that LED light stimulation was activate superior colliculus region in mouse brain. And the most higher activated value of segmentation method was using tissue probability map. this study may help to improve brain activation study using EPI and SPM analysis.

In-vivo Studies on Effect of Lipo-PGE1 on Neoangiogenesis of Composite Graft in a Rabbit Model (가토모델에서 Lipo-PGE1이 복합조직이식편의 미세혈관신생에 미치는 영향)

  • Park, Ji-Ung;Eo, Su-Rak;Cho, Sang-Hun;Choi, Jong-Sun;Kim, Eo-Jin
    • Archives of Plastic Surgery
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    • v.37 no.6
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    • pp.721-725
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    • 2010
  • Purpose: The survival of composite graft is dependent on three steps, (1) plasmatic imbibitions, (2) inosculation, and (3) neovascularization. Among the many trials to increase the survival rate of composite graft, prostaglandin E1 (PGE1) has beneficial effects on the microcirculatory level with vasodilating, antithrombotic, anti-inflammatory and neoangiogenic properties. Lipo-PGE1 which is lipid microspheres containing PGE1 had developed to compensate the systemic and local side effects of PGE1. This study was proposed to determine whether Lipo-PGE1 administration enhanced the survival of composite graft through neovascularization quantitatively in a rabbit ear model. Methods: Fourteen New Zealand White Rabbits each weighing 3~4 kg were divided in two groups: (1) intravenous Lipo-PGE1 injection group and (2) control group. A $2{\times}1\;cm$ sized, full-thickness rectangular composite graft was harvested in each auricle. Then, the graft was reaaproximated in situ using a 5-0 nylon suture. For the experimental group, $3{\mu}g$/kg/day of Lipo-PGE1 ($5{\mu}g$/mL) was administered intravenously through the marginal vein of the ear for 14 days. The control group was received no pharmacologic treatment. On the 14th postoperative day, composite graft of the ear was harvested and immunochemistry staining used Monoclonal mouse anti-CD 31 antibody was performed. Neoangiogenesis was quantified by counting the vessels that showed luminal structures surrounded by the brown color-stained epithelium and counted from 10 random high-power fields (400x) by independent blinded observer. Statistical analysis (Wilcoxon Signed Ranks test for nonparametric data) was performed using SPSS v12.0, with values of p<0.05 considered significant. Results: The mean number of the microvessels was $15.48{\pm}8.65$ in the experimental group and $9.82{\pm}7.25$ in the control group (p=0.028). Conclusion: The use of Lipo-PGE1 facilitated the neoangiogenesis, resulted in the improvement of the survival rate of graft. On the basis of this results, we could support wider application of Lipo-PGE1 for more effective therapeutic angiogenesis and successful survival in various cases of composite graft in the human.

A Study on the Emotional Characteristics of Patients within One Year of Stroke Using Core Seven Emotions Inventory-Short Form (발병기간 1년 이내 뇌졸중 환자의 핵심 감정척도 단축형을 활용한 정서적 특성 연구)

  • Son, Sung Eun;Lee, Ga Won;Lee, Na Hyun;Chae, Han nah;Cheong, Moon Ju;Kang, Hyung Won;Lyu, Yeoung Su
    • Journal of Oriental Neuropsychiatry
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    • v.30 no.3
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    • pp.165-175
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    • 2019
  • Objectives: This study was conducted to investigate the emotional characteristics of the patients within one year after stroke using the Core Seven Emotions Inventory-Short Form. Methods: It analyzed the medical records of 39 stroke patients who had visited W University hospital and completed the Core Seven-Emotions Inventory-Short Form (CSEI-S), the K-MBI, the PWI-SF, and the HADS. Patients data were analyzed by descriptive analysis, frequency analysis, the Mann-Whitney U test, and the nonparametric test of the CSEI according to the period of stroke onset in patients and Spearman's correlation analysis using the SPSS (Statistical Package for the Social Science, IBM, United States of America) Version 23.0. Results: First, in the case of depression, all subjects were in the danger group, although more than half of the joy, anger, thinking, sadness and fear were included in the normal group in the shortening of the key seven-point scale. Secondly, in measuring the social and psychological stress and hospital anxiety and depression, social and psychological stress were indicated to be a potential danger group, while anxiety and depression were shown to be a healthy group. Thirdly, the emotional characteristics were explored according to the sub-factor of the shortening of the key seven-figure emotional scale after being classified within two months, between two and six months and over six months depending on the duration of the outbreak. As a result, statistically significant, Joy was the highest score over six months and the lowest score between two and six months. On the other hand, the case of depression was depicted to be significantly lower at over six months, and was highest between two and six months. Finally, the correlations on each scale were statistically significant. Conclusions: This study provided that the CSEI-S can be used to simply to measure the emotions of patients according to the period of the onset of stroke in the clinical scene.

Classical testing based on B-splines in functional linear models (함수형 선형모형에서의 B-스플라인에 기초한 검정)

  • Sohn, Jihoon;Lee, Eun Ryung
    • The Korean Journal of Applied Statistics
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    • v.32 no.4
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    • pp.607-618
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    • 2019
  • A new and interesting task in statistics is to effectively analyze functional data that frequently comes from advances in modern science and technology in areas such as meteorology and biomedical sciences. Functional linear regression with scalar response is a popular functional data analysis technique and it is often a common problem to determine a functional association if a functional predictor variable affects the scalar response in the models. Recently, Kong et al. (Journal of Nonparametric Statistics, 28, 813-838, 2016) established classical testing methods for this based on functional principal component analysis (of the functional predictor), that is, the resulting eigenfunctions (as a basis). However, the eigenbasis functions are not generally suitable for regression purpose because they are only concerned with the variability of the functional predictor, not the functional association of interest in testing problems. Additionally, eigenfunctions are to be estimated from data so that estimation errors might be involved in the performance of testing procedures. To circumvent these issues, we propose a testing method based on fixed basis such as B-splines and show that it works well via simulations. It is also illustrated via simulated and real data examples that the proposed testing method provides more effective and intuitive results due to the localization properties of B-splines.

Effects of thickness and background on the masking ability of high-trasnlucent zirconias (고투명도 지르코니아의 두께 및 하부 배경에 따른 색조 차단 효과)

  • Kim, Young-Gon;Jung, Ji-Hye;Kong, Hyun-Jun;Kim, Yu-Lee
    • Journal of Dental Rehabilitation and Applied Science
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    • v.37 no.4
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    • pp.199-208
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    • 2021
  • Purpose: The purpose of this study was to compare and evaluate the masking ability of three types of high translucent zirconia according to the various thicknesses and backgrounds. Materials and Methods: Using three types of high-translucency zirconia (Ceramill zolid fx white, Ceramill zolid ht+ white, Ceramill zolid ht+ preshade A2), 10 cylindrical specimens were fabricated in 10mm diameter and each with four thicknesses (0.6 mm, 1.0 mm, 1.5 mm, 2.0 mm), respectively by CAD/CAM method. The background was 10 mm in diameter and 10 mm in thickness. A1, A2, A3 flowable resin backgrounds, blue-colored core resin background, and Ni-Cr alloy background were prepared, and black, white backgrounds provided by the spectrophotometer manufacturer (x-rite, Koblach, Austria) were used. zirconia specimens and the background specimen were stacked to measure L, a*, b* with Spectrophotometer (Color i5, x-rite, Koblach, Austria) and the ΔE value with the other background is calculated. The Calculated mean ΔE values were compared based on perceptibility threshold 1.0 and acceptability threshold 3.7. Nonparametric tests such as Kruskal-Wallis test were performed to verify statistical significance (α = 0.05). Results: There was a significant difference in the mean ΔE value according to the zirconia type, background and thickness change (P = 0.000). Conclusion: According to the results of this study, the pre-colored high-translucent zirconia can obtain the desired zirconia shade when it is restored on teeth, composite resins, and abutments except for the blue resin core.

Case study on the effects of VR educational media on oral imaging practice (치위생학과 구강영상학실습 수업에서의 VR활용에 관한 사례 연구)

  • Choi, Yong-Keum;Lim, Kun-Ok
    • Journal of Korean society of Dental Hygiene
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    • v.22 no.5
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    • pp.323-332
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    • 2022
  • Objectives: This study aims to confirm the educational necessity and utilization of VR media. And it was conducted to prepare basic data necessary for the use of VR in various dental hygiene education in the future and the development of innovative practical training courses. Methods: Before and after using VR in oral radiology practice classes, learning interest (4 items), learning commitment (9 items), learning motivation (5 items), educational media preference (4 items), and satisfaction (10 items) were investigated and analyzed. Friedman two way ANOVA by ran a nonparametric analysis corresponding to repeated measures ANOVA was performed. The statistical significance level was 0.05. Results: It was found that there were statistically significant differences in learning interest, learning immersion, and learning motivation according to the type of oral radiology practice education medium (p<0.05). Conclusions: VR is expected that the use of learning media using VR will lead to students' interest, immersion, and learning motivation in class, and that positive learning effects on VR education media can be sufficiently obtained.

Risk Factor's Affecting long-term Outcome of Alport syndrome (Alport 증후군의 예후와 관련된 위험요인 분석)

  • Byun Ji-Yoon;Baek Seoung-Yon;Lee Young-Mock;Kim Ji-Hong;Lee Jae Seung;Kim Pyung-Kil;Hong Soon-Won;Jeong Hyeon-Joo;Kim Soon-Il;Kim Yu-Seun;Park Ki-Il
    • Childhood Kidney Diseases
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    • v.5 no.2
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    • pp.164-175
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    • 2001
  • Purpose : Alport syndrome is a hereditary nephrotic disease characterized by progressive nephrotic symptom, sensorineural hearing loss, ophthalmic abnormality, typical microscopic findings, and familial occurrence. In this study, we tried to find the risk factors related with its prognosis by taking a close observation on clinical symptoms of children with Alport syndrome reviewing retrospectively. Materials & methods : We chose children diagnosed as Alport syndrome in renal biopsy during 20 years(from 1980, Jan. until 1999, Dec.) who could receive follow up studies in tile department of pediatrics. They were divided into two groups by comparing renal function at the time of diagnosis and at current status. We compared several clinical aspects in them, and applied nonparametric test for statistical analysis. Results : The sex ratio(male:female) of 24 children was 3:1. The most common clinical symptom presented at their first visit was gross hematuria. Among those 24 children, 11 cases($46\%$) of progressing into chronic renal failure(Group II) were observed. Hypertension, proteinuria and edema were seen much frequently in group II. The level of serum protein, albumin, and creatinine clearance were decreased while BUN, creatinine were relatively increased. All the results were statistically significant. Conclusion Clinically significant risk factors related to prognosis in Alport syndrome were the presence of hypertension, edema, and proteinuria at the time of diagnosis. Also, the level of serum protein, albumin, BUN, creatinine, and glomerular filtration rate were proved to be important factors in predicting prognosis. We believe that studies on these possible risk factors would be of great help in treating and predicting prognosis of children suffering with Alport syndrome. (J Korean Soc Pediatr Nephrol 2001;5 : 164-75)

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Effect of K University Dental Hygiene Department students' participation in overseas clinical practice on satisfaction with practice, major, and intention to work abroad (K 대학교 치위생학과 학생의 해외임상실습참여가 임상실습만족도, 전공만족도 및 해외취업의사에 미치는 영향)

  • Min-Sun Lee;Ma I Choi
    • Journal of Korean Dental Hygiene Science
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    • v.6 no.2
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    • pp.151-160
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    • 2023
  • Background: This study analyzed the differences in practice satisfaction, major, and willingness to work abroad among dental hygiene department students at K University in Gangwon-do based on their participation in international practicums. Methods: A survey was conducted on a total of 215 students through convenience sampling of dental hygiene students, and the final 214 responses were analyzed. General characteristics were examined. Major satisfaction and grades were measured on a 5-point Likert scale. And satisfaction with practice, intention to participate in international practicums, and employment were investigated by papers. Descriptive statistical analysis was performed on general characteristics using SPSS software (version 26.0). Due to the convenience sample, nonparametric analysis was used to determine satisfaction with practice and major according to general characteristics using the Mann-whitney U and Kruskal-wallis test. An independent samples t-test was conducted to determine the difference between practice satisfaction and major satisfaction depending on participation in international practicums, and Fisher's exact test was conducted to determine practice satisfaction, willingness to participate in overseas internships, and employment. Results: Concerning future participation in international clinical practicums, 66.7% of students who had previously participated in overseas training expressed willingness to engage again. 40.9% of those who had not participated showed no intention of participating, and there was a significant difference (p<0.05). Additionally, 76.2% of the participants expressed interest in overseas employment, with this difference also being statistically significant (p<0.05). Conclusion: It was confirmed that students' satisfaction with practice and major increased through participation in international practicums, and that they had a positive intention to work abroad and participate in overseas internship programs in the future.