• Journal of Korean Society of Water and Wastewater
• /
• v.28 no.3
• /
• pp.265-276
• /
• 2014

In this study, we suggested 4 plans to reduce non-point pollutant sources in Dongcheon and analyzed their controlling effects by water quality modeling, XP-SWMM. To do this we identified the influx of non-point pollutant sources to the initial rainwater through the water quality survey in the river and analyzed the causes of them at major locations, and suggested 4 kinds of plans reducing non-point pollutant sources. Plans reducing the non-point pollutant sources through cleaning the industrial road around the river(plan A), through a separate treatment facilities like the gutter(plan B), through installing treatement facilities(plan C), or through combing plan B and C(plan D) were analyzed using XP-SWMM model. The analysis showed that plan A, B, C and D reduced non-point pollutant sources average 21.7 %, 24.7 %, 49.3 %, 56.7 % respectively. Therefore, the water quality pollution in Dongcheon due to the influx of non-point pollutant sources is considered to be reduced effectively though cleaning the road, installed at the exits of paddy or factory basins, invasion type facilities or equipment-type facilities.

• 한국연소학회:학술대회논문집
• /
• 2004.06a
• /
• pp.49-56
• /
• 2004

A two-dimensional twin-jet counterflow system has been designed, in which two streams from two double-slit nozzles form a counterflow. This flow system enables one to systematically investigate various effects on non-premixed flames, including the non-premixed flame interaction, the edge flame behavior and the effect of curvature. Non-premixed flame interaction in the twin-jet counterflow system has been investigated numerically for methane fuel diluted with nitrogen. Three types of non-premixed flame(conventional counterflow flame, crossed twin-jet flame and petal shaped flame) were simulated depending on the combination of fuel/oxidizer supply to each nozzle. The extinction characteristics of non premixed methane flame in the twin-jet counterflow have been investigated numerically. The boundary of the existence of petal-shaped flames was identified for the twin-jet counterflow flames. Due to the existence of the unique petal-shaped flames, the extinction boundary for the twin-jet counterflow can be extended significantly compared to that for the conventional counterflow non-premixed flames, through the interaction of two flames. Through the comparison of the crossed twin-jet flame and the conventional counterflow flame, structure of the crossed twin-jet counterflow flame is analysed. Through the comparison of the petal shaped flame and the conventional counterflow flame, the extension of the extinction boundary for the twin-jet counterflow is investigated.

• Journal of applied mathematics & informatics
• /
• v.42 no.3
• /
• pp.511-520
• /
• 2024

In this paper, we introduce the concept of split and non-split tree (D, C)- set of a connected graph G and its associated color variable, namely split tree (D, C) number and non-split tree (D, C) number of G. A subset S ⊆ V of vertices in G is said to be a split tree (D, C) set of G if S is a tree (D, C) set and ⟨V - S⟩ is disconnected. The minimum size of the split tree (D, C) set of G is the split tree (D, C) number of G, γ_χST (G) = min{|S| : S is a split tree (D, C) set}. A subset S ⊆ V of vertices of G is said to be a non-split tree (D, C) set of G if S is a tree (D, C) set and ⟨V - S⟩ is connected and non-split tree (D, C) number of G is γ_χST (G) = min{|S| : S is a non-split tree (D, C) set of G}. The split and non-split tree (D, C) number of some standard graphs and its compliments are identified.

• Genomics & Informatics
• /
• v.17 no.4
• /
• pp.42.1-42.6
• /
• 2019

Robust identification of genetic alterations is important for the diagnosis and subsequent treatment of tumors. Screening for genetic alterations using tumor tissue samples may lead to biased interpretations because of the heterogeneous nature of the tumor mass. Liquid biopsy has been suggested as an attractive tool for the non-invasive follow-up of cancer treatment outcomes. In this study, we aimed to verify whether the mutations identified in primary tumor tissue samples could be consistently detected in plasma cell-free DNA (cfDNA) by digital polymerase chain reaction (dPCR). We first examined the genetic alteration profiles of three colorectal cancer (CRC) tissue samples by targeted next-generation sequencing (NGS) and identified 11 non-silent amino acid changes across six cancer-related genes (APC, KRAS, TP53, TERT, ARIDIA, and BRCA1). All three samples had KRAS mutations (G12V, G12C, and G13D), which were well-known driver events. Therefore, we examined the KRAS mutations by dPCR. When we examined the three KRAS mutations by dPCR using tumor tissue samples, all of them were consistently detected and the variant allele frequencies (VAFs) of the mutations were almost identical between targeted NGS and dPCR. When we examined the KRAS mutations using the plasma cfDNA of the three CRC patients by dPCR, all three mutations were consistently identified. However, the VAFs were lower (range, 0.166% to 2.638%) than those obtained using the CRC tissue samples. In conclusion, we confirmed that the KRAS mutations identified from CRC tumor tissue samples were consistently detected in the plasma cfDNA of the three CRC patients by dPCR.

• Plant Biotechnology Reports
• /
• v.4 no.4
• /
• pp.311-319
• /
• 2010

Lettuce is an economically important leafy vegetable that accumulates a milk-like sap called latex in the laticifer. Previously, we conducted a large-scale lettuce latex proteomic analysis. However, the identified proteins were obtained only from lettuce ESTs and proteins deposited in NCBI databases. To extend the number of known latex proteins, we carried out an analysis identifying 302 additional proteins that were matched to the NCBI non-redundant protein database. Interestingly, the newly identified proteins were not recovered from lettuce EST and protein databases, indicating the usefulness of this hetero system in MudPIT analysis. Gene ontology studies revealed that the newly identified latex proteins are involved in many processes, including many metabolic pathways, binding functions, stress responses, developmental processes, protein metabolism, transport and signal transduction. Application of the non-redundant plant protein database led to the identification of an increased number of latex proteins. These newly identified latex proteins provide a rich source of information for laticifer research.

• Asian-Australasian Journal of Animal Sciences
• /
• v.32 no.2
• /
• pp.290-296
• /
• 2019

Objective: Pigs share many physiological, anatomical and genomic similarities with humans, which make them suitable models for biomedical researches. Understanding the genetic status of Yucatan miniature pigs (YMPs) and their association with human diseases will help to assess their potential as biomedical model animals. This study was performed to identify non-synonymous single nucleotide polymorphisms (nsSNPs) in selective sweep regions of the genome of YMPs and present the genetic nsSNP distributions that are potentially associated with disease occurrence in humans. Methods: nsSNPs in whole genome resequencing data from 12 YMPs were identified and annotated to predict their possible effects on protein function. Sorting intolerant from tolerant (SIFT) and polymorphism phenotyping v2 analyses were used, and gene ontology (GO) network and Kyoto encyclopedia of genes and genomes (KEGG) pathway analyses were performed. Results: The results showed that 8,462 genes, encompassing 72,067 nsSNPs were identified, and 118 nsSNPs in 46 genes were predicted as deleterious. GO network analysis classified 13 genes into 5 GO terms (p<0.05) that were associated with kidney development and metabolic processes. Seven genes encompassing nsSNPs were classified into the term associated with Alzheimer's disease by referencing the genetic association database. The KEGG pathway analysis identified only one significantly enriched pathway (p<0.05), hsa04080: Neuroactive ligand-receptor interaction, among the transcripts. Conclusion: The number of deleterious nsSNPs in YMPs was identified and then these variants-containing genes in YMPs data were adopted as the putative human diseases-related genes. The results revealed that many genes encompassing nsSNPs in YMPs were related to the various human genes which are potentially associated with kidney development and metabolic processes as well as human disease occurrence.

• Journal of Home Health Care Nursing
• /
• v.13 no.1
• /
• pp.33-45
• /
• 2006

Purpose : The purpose of this study is to present the desirable level of home health care services by identifying the roles and activities by task of home health nursing specialists as well as to raise the level of professionalism in home health care services. Method : This is a methodological study. The roles and activities by task were identified through a review of literature and a state-of-the-practice survey, and were structured into a questionnaire after being reviewed and modified through a consensus of experts. The field survey was conducted on 136 home health nursing specialists at medical institutions, public health centers. public medical institutions, non-governmental organizations, and religious institutions in Seoul, Gyeonggi Province. Incheon, Busan, Daegu, and Gwanggju from June 4 to August 4. 2004. Seven roles. 34 tasks and 130 activities were identified in association with home health nursing specialists. Result : The roles of home health nursing specialists were identified as professional nursing service provider, advisor, educator, administrator, case manager, researcher and leader. Under these roles. 34 tasks and 134 task-specific activities were identified. Conclusion : The the roles and activities of home health nursing specialist identified in this study can be used in various home health care settings. These the roles and activities should provide the evaluation criteria of home health care services for institutions with existing home health care programs. An evaluation tool should be developed in order to ensure the hish quality of home health care services.

• Research in Mathematical Education
• /
• v.12 no.4
• /
• pp.251-258
• /
• 2008

This paper deals with factors discriminating mathematically gifted and non-gifted students. Discussion of some characteristics of mathematically gifted students is done in the first session. Several factors distinguish mathematically gifted from the non-gifted students. High mathematical creativity, high intelligence and opinion of teachers are some of the key factors that can be used for discriminating mathematically gifted and non-gifted students. Research studies have revealed that cognitive as well as affective factors will enhance giftedness. In this study the investigator wishes to look in detail about the characteristics of mathematically gifted students and how they can be identified. Anyway, teachers can change environmental factors and maximum outcome of giftedness can be ensured."

• Ocean Systems Engineering
• /
• v.10 no.3
• /
• pp.267-287
• /
• 2020

The dropped objects are identified as one of the top ten causes of fatalities and serious injuries in the oil and gas industry. It is of importance to understand dynamics of dropped objects under water to accurately predict the motion of dropped objects and protect the underwater structures and facilities from being damaged. In this paper, we study non-dimensionalization of two-dimensional (2D) theory for dropped cylindrical objects. Non-dimensionalization helps to reduce the number of free parameters, identify the relative size of effects of force and moments, and gain a deeper insight of the essential nature of dynamics of dropped cylindrical objects under water. The resulting simulations of dimensionless trajectory confirms that drop angle, trailing edge and drag coefficient have the significant effects on dynamics of trajectories and landing location of dropped cylindrical objects under water.

• Korean Journal of Child Studies
• /
• v.30 no.3
• /
• pp.113-125
• /
• 2009

This study advances knowledge of developmental patterns in poverty and delinquency; data was obtained from waves 1-5 (2003-2007) of the Korea Youth Panel Survey. Semi-parametric group-based modeling (SGM) identified 4 trajectories of poverty from age 13 to 17 : non-poor, poverty increasing, low-level continuous poverty and chronic poverty groups and five developmental trajectories of delinquency : non-offending, late onset, low-level continuous, desisting, and chronic groups. A joint trajectory method predicted patterns of delinquency conditional on poverty trajectories. Chronic and low-level continuous poverty groups were more likely than others to follow chronic trajectories of delinquency; the non-poor group was more likely to be non-offending. Implications of this study for youth welfare were discussed to reduce risk for delinquency.