• 한국응용과학기술학회지
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• 제30권4호
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• pp.688-700
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• 2013

하수 슬러지로부터 추출된 유지를 이용하여 바이오디젤 생산에 대해 고찰하였다. 바이오디젤 생산의 밝은 전망에도 불구하고, 이를 상용화하기 위한 노력은 매우 제한되어 있다. 주요 장애물 중 하나는 전체 생산비용의 약 70~75%를 구성하는 정제 유지의 공급 원료와 연관된 높은 가격이다. 따라서 이를 극복하기 위하여 폐유나 낮은 품질 유지 등의 저가 원료를 사용하여 바이오디젤의 생산 비용을 낮추는 기술이 제안되어 왔다. 이런 측면에서 하수 슬러지로부터 추출된 유지는 비교적 저렴하여 유망한 원료로 평가받고 있다. 본 연구에서는 하수 슬러지로부터 추출된 유지를 이용한 바이오디젤의 생산기술을 검토하였다. 하수 슬러지로부터 유지 추출공정 및 에스테르화 전환공정 및 무촉매 열화학 전환공정을 살펴보았다.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2007년도 춘계종합학술대회
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• pp.678-681
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• 2007

본 연구에서는 오실로메크릭법에 의한 혈압측정을 위하여 비관혈적인 방법으로 보다 정확하게 혈압을 추정할 수 있는 시스템을 구현하였다. 구현된 혈압 측정 시스템은 압력 제어부, 신호 측정부 그리고 혈압 신호처리부, 무선센서네트워크부 등으로 구성하였다. 구현된 혈압측정 실험 시스템의 타당성을 검증하기 위하여 압력 측정부의 특성 평가 실험, 혈압 추정을 위한 특성비율 산출 실험, 오실로 메트릭법에 의한 혈압 추정 및 평가 실험을 수행하였다. 본 연구에서 구현된 혈압 측정 실험 시스템으로 성인남성 5명을 실험 대상군으로 선정하여 데이터를 계측하고 혈압을 추정하는 실험을 한 결과 오실로메트릭에 의한 혈압 추정 및 평가 실험에서 청진법과의 평균동맥압, 수축기 혈압, 그리고 이완기 혈압에서 최대 절대편차 비율이 각각 1.38 %, 1.63 그리고 2.97 % 이었고 최대 표준오차가 각각 5.00, 3.72, 그리고 4.34인 혈압 측정 시스템을 구현하였다.

• Journal of Microbiology and Biotechnology
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• 제20권2호
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• pp.356-362
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• 2010

Ceramide is important not only for the maintenance of the barrier function of the skin but also for the water-binding capacity of the stratum corneum. Although the exact role of ceramide in the human skin is not fully understood, ceramide has become a widely used ingredient in cosmetic and pharmaceutical industries. Compared with other microorganisms, yeast is more suitable for the production of ceramide because yeast grows fast and is non-toxic. However, production of ceramide from yeast has not been widely studied and most work in this area has been carried out using Saccharomyces cerevisiae. Regulating the genes that are involved in sphingolipid synthesis is necessary to increase ceramide production. In this study, we investigated the effect of the genes involved in the synthesis of ceramide, lcb1, lcb2, tsc10, lac1, lag1, and sur2, on ceramide production levels. The genes were cloned into pYES2 high copy number vectors. S. cerevisiae was cultivated on YPDG medium at $30^{\circ}C$. Ceramide was purified from the cell extracts by solvent extraction and the ceramide content was analyzed by HPLC using ELSD. The maximum production of ceramide (9.8 mg ceramide/g cell) was obtained when the tsc10 gene was amplified by the pYES2 vector. Real-time RT-PCR analysis showed that the increase in ceramide content was proportional to the increase in the tsc10 gene expression level, which was 4.56 times higher than that of the control strain.

• Journal of Korean Neurosurgical Society
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• 제48권1호
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• pp.14-19
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• 2010

Objective : Allelic losses or loss of heterozygosity (LOH) at many chromosomal loci have been found in the cells of meningiomas. The objective of this study was to evaluate LOH at several loci of different chromosomes (1p32, 17p13, 7q21, 7q31, and 22q13) in different grades of meningiomas. Methods : Forty surgical specimens were obtained and classified as benign, atypical, and anaplastic meningiomas. After DNA extraction, ten polymorphic microsatellite markers were used to detect LOH. Medical and surgical records, as well as pathologic findings, were reviewed retrospectively. Results : LOH at 1p32 was detected in 24%, 60%, and 60% in benign, atypical, and anaplastic meningiomas, respectively. Whereas LOH at 7q21 was found in only one atypical meningioma. LOH at 7q31 was found in one benign meningioma and one atypical meningioma. LOH at 17p13 was detected in 4%, 40%, and 80% in benign, atypical, and anaplastic meningiomas, respectively. LOH at 22q13 was seen in 48%, 60%, and 60% in benign, atypical, and anaplastic meningiomas, respectively. LOH results at 1p32 and 17p13 showed statistically significant differences between benign and non-benign meningiomas. Conclusion : LOH at 1p32 and 17p13 showed a strong correlation with tumor progression. On the other hand, LOH at 7q21 and 7q31 may not contribute to the development of the meningiomas.

• 한국콘텐츠학회:학술대회논문집
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• 한국콘텐츠학회 2009년도 춘계 종합학술대회 논문집
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• pp.927-932
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• 2009

컴퓨터를 이용한 디지털 기술의 상호작용성은 창작의 도구와 재료를 제공하는 것은 물론 민주적 커뮤니케이션의 도구로서 참여성이라는 특징까지 가지고 있다. 본 논문은 이러한 상호 작용성을 기반으로 소리와 색의 정보교환을 통해, 각 정보의 디지털화를 통해 과학적인 공감각적인 작품 제작을 하기 위한 선행연구이다. 선행연구는 우선 사람들의 색채와 소리에 대한 감성 인지 특징의 분석을 통하여 사람들의 색채와 음악에 대한 감성 인지를 비교하고 연관시킨다. 형태를 뺀 이미지의 컬러분석을 통해서 감성을 기반으로 한 컬러를 어떻게 소니피케이션할 수 있는지에 대한 과학적인 기초 알고리즘 제작을 위한 연구이다. 카메라로 끊임없이 변환하는 색채를 포착하는 것을 통하여 실시간 인터랙티브 디지털 음악으로 전환함으로써, 본 연구의 이론적 결과를 바탕으로 실험 음악 작곡의 기초 알고리즘을 제작한다.

• 대한임상독성학회지
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• 제10권2호
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• pp.103-110
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• 2012

Purpose: The aim of this study was to evaluate the cardiovascular manifestations and clinical course in patients with acute carbon monoxide poisoning. Methods: A retrospective study was conducted over a 36 month period on consecutive patients who visited an emergency medical center and were diagnosed with acute carbon monoxide poisoning. A standardized data extraction protocol was performed on the selected patients. Results: A total of 293 patients were selected during the study period. Cardiac manifestations were observed in 35.2% (n=103) of the patients: hypotension in 11 patients (3.8%), ECG abnormalities in 44 patients (15.0%) and cardiac enzyme abnormalities in 103 patients (35.2%). Echo cardiography was performed on 56 patients with cardiac toxicity: 12 patients had abnormal results (5 patients with global hypokinesia and 7 patients with regional wall akinesia). Five patients died within 3 hours after ED admission, and the remaining patients were discharged alive. At 3 months after discharge, none of these patients had died.The SOFA scores in the severe cardiac toxicity group and non-severe cardiac toxicity group at the time of arrival were $2.53{\pm}2.29$ and $2.19{\pm}2.12$, respectively (p=0.860). Conclusion: Cardiovascular manifestations occur after acute CO poisoning at arateof 35.2%. Even those with severe cardiovascular toxicity recovered well within 10 days after admission. Therefore, the importance of cardiac toxicity after acute CO poisoning is not significant in itself in the clinical course, and the short-term prognosis of cardiac toxicity is unlikely to be unfavorable in acute CO poisoning.

• Bulletin of the Korean Chemical Society
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• 제26권4호
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• pp.529-536
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• 2005

Measurement of toxicologically relevant polychlorinated biphenyl (PCB) congeners such as non-ortho(IUPAC#) 77, 81, 126, 169 and mono-ortho 105, 114, 118, 123, 156, 157, 189 and di-ortho 170, 180 and polybrominated diphenyl ethers (PBDEs) such as 47, 66, 85, 99, 100, 138, 153, 154 in environmental samples become almost mandatory in several countries now. However, most of the available methods involve expensive instrumentations such as HRGC-HRMS or ECNI-LRMS, apart from expensive extraction and clean-up (with large volume of solvents) steps. A method has been devised combining the analytical separation power of PYE [2-(1-pyrenyl)ethyldimethysilylated silica] column HPLC and high-resolution gas chromatographic techniques including micro-electron capture detection (ECD) and two dimensional gas chromatograpy-ECD techniques to determine these eco-toxic substances at parts-per-trillion (ppt) levels. This combination resolves co-elution of congeners that occur in disproportionate ratios (e.g. CB-110 and -77) and allows accurate congener-specific determination of target compounds. This method is cost effective as it requires only hexane, that in small quantities (10 mL) and GC-ECD. The elution and analysis time are optimized to less man hours. This method is effectively utilized in the analysis of co-planar PCBs and PBDEs from archived solvent extracts of samples previously analyzed for pesticides and PCBs. Structure based separation of contaminant classes improves GCECD determination at ppt levels.

• Wind and Structures
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• 제20권6호
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• pp.763-791
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• 2015

"Wind and Ports" is a European project that has been carried out since 2009 to handle wind forecast in port areas through an integrated system made up of an extensive in-situ wind monitoring network, the numerical simulation of wind fields, the statistical analysis of wind climate, and algorithms for medium-term (1-3 days) and short term (0.5-2 hours) wind forecasting. The in-situ wind monitoring network, currently made up of 22 ultrasonic anemometers, provides a unique opportunity for detecting high resolution thunderstorm records and studying their dominant characteristics relevant to wind engineering with special concern for wind actions on structures. In such a framework, the wind velocity of thunderstorms is firstly decomposed into the sum of a slowly-varying mean part plus a residual fluctuation dealt with as a non-stationary random process. The fluctuation, in turn, is expressed as the product of its slowly-varying standard deviation by a reduced turbulence component dealt with as a rapidly-varying stationary Gaussian random process with zero mean and unit standard deviation. The extraction of the mean part of the wind velocity is carried out through a moving average filter, and the effect of the moving average period on the statistical properties of the decomposed signals is evaluated. Among other aspects, special attention is given to the thunderstorm duration, the turbulence intensity, the power spectral density and the integral length scale. Some noteworthy wind velocity ratios that play a crucial role in the thunderstorm loading and response of structures are also analyzed.

• 한국주거학회논문집
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• 제24권6호
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• pp.199-208
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• 2013

Developing a modern Han-style design and providing support for the commercialization development model in recent years has been propelled by the Han-style Support Strategies of the central government in conjunction with Han-style revitalization related projects that reflect the efforts of local governments. Han-style revitalization, the rekindling and revaluing of human behavior and interest in local governments following the social and cultural changes of the past decades, has emerged as an increasingly traditional area of concern in Han-style design. The purpose of the study was to provide a method which clarifies the design rules of the Han-style bathroom based on an evaluation of sensibilities and a rough set theory, and to give the components meaning and to systematize the method. Essentially, the Han-style bathroom design evaluation is a complex multi-criteria decision making process that seeks to improve the effectiveness and objectively of the Han-style bathroom design. Han-style bathroom design can be displayed in a graphical representation in response to input from the evaluation concerning sensibilities. Because the graphical representation is composed of 3D data, it is possible to display the Han-style bathroom design form in any desired perspective and also to perform shading and other operations. With the proposed method, it is possible to obtain a combination of several contributory components which can be referred to as Reducts, Covering Index and Column Score. Han-Style/Non Han-Style Bathroom Designs were identified by the combination of several components.

• 한국전자통신학회논문지
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• 제15권3호
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• pp.513-520
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• 2020

최근 기계 학습을 활용한 비전 검사 시스템의 개발이 활발해지고 있다. 본 연구는 기계 학습을 활용한 결함 검사 모델을 개발하고자 한다. 이미지에 대한 결함 검출 문제는 기계 학습에 있어 지도 학습 방법인 분류 문제에 해당한다. 본 연구에서는 특징을 자동 추출하는 알고리즘과 특징을 추출하지 않는 알고리즘을 기반으로 결함 검출 모델을 개발한다. 특징을 자동 추출하는 알고리즘으로 1차원 합성곱 신경망과 2차원 합성곱 신경망을 활용하였으며, 특징을 추출하지 않는 알고리즘으로 다중 퍼셉트론, 서포트 벡터 머신을 활용하였다. 4가지 모델을 기반으로 결함 검출 모델을 개발하였고 이들의 정확도와 AUC를 기반으로 성능 비교하였다. 이미지 분류는 합성곱 신경망을 활용한 모델 개발이 일반적임에도, 본 연구에서 이미지의 화소를 RGB 값으로 변환하여 서포트 벡터 머신 모델을 개발할 때 높은 정확도와 AUC를 얻을 수 있었다.