• Title/Summary/Keyword: Non-decision Making

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Prognostic Factors and Scoring Systems for Non-Small Cell Lung Cancer Patients Harboring Brain Metastases Treated with Gamma Knife Radiosurgery

  • Eom, Jung-Seop;Cho, Eun-Jung;Baek, Dong-Hoon;Lee, Kyung-Nam;Shin, Kyung-Hwa;Kim, Mi-Hyun;Lee, Kwang-Ha;Kim, Ki-Uk;Park, Hye-Kyung;Kim, Yun-Sung;Park, Soon-Kew;Cha, Seong-Heon;Lee, Min-Ki
    • Tuberculosis and Respiratory Diseases
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    • v.72 no.1
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    • pp.15-23
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    • 2012
  • Background: The survival of non-small cell lung cancer (NSCLC) patients with brain metastases is reported to be 3~6 months even with aggressive treatment. Some patients have very short survival after aggressive treatment and reliable prognostic scoring systems for patients with cancer have a strong correlation with outcome, often supporting decision making and treatment recommendations. Methods: A total of one hundred twenty two NSCLC patients with brain metastases who received gamma knife radiosurgery (GKRS) were analyzed. Survival analysis was calculated in all patients for thirteen available prognostic factors and four prognostic scoring systems: score index for radiosurgery (SIR), recursive partitioning analysis (RPA), graded prognostic assessment (GPA), and basic score for brain metastases (BSBM). Results: Age, Karnofsky performance status, largest brain lesion volume, systemic chemotherapy, primary tumor control, and medication of epidermal growth factor receptor tyrosine kinase inhibitor were statistically independent prognostic factors for survival. A multivariate model of SIR and RPA identified significant differences between each group of scores. We found that three-tiered indices such as SIR and RPA are more useful than four-tiered scoring systems (GPA and BSBM). Conclusion: There is little value of RPA class III (most unfavorable group) for the same results of 6-month and 1-year survival rate. Thus, SIR is the most useful index to sort out patients with poorer prognosis. Further prospective trials should be performed to develop a new molecular- and gene-based prognostic index model.

Analysis of Socio-economic Effects of Land Consolidation and On-farm Development Project (경지정리사업(耕地整理事業)의 사회경제적효과분석(社會經濟的效果分析))

  • Lim, Jae Hwan;Kim, Jae Hong;Yeo, Soon Duck
    • Korean Journal of Agricultural Science
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    • v.27 no.2
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    • pp.158-175
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    • 2000
  • Up to date, the economic feasibility analysis on land consolidation and on-farm development projects were mainly depended upon the direct benefits from market value of project outputs. Therefore the projects were neglected in allocation of the government's financial funds and loans on account of undervaluation of the project benefits including socio-economic and environmental values of the projects. Accordingly the Extended Benefit Cost Analysis Method should be adapted to cover not only the benefits such as non-market values of environmental functions of the projects and but also the economic market values of the project outputs. The main objectives of this study is (1) to provision of the guideline for economic feasibility analysis based on the IBRD and ADB guidelines, (2) to estimate the benefits such as Productivity increase effect, labor saving effect, off-farm income increase effect during off-farm season, saving of O&M cost of farm mechanization, enhance of farmer's public health, increase of environmental public function of paddy fields, effect of food security and establishment of peaceful and uncontroversial rural society by implementing the land consolidation and on-farm development, (3) to introduce the newly adapted analytical method as the extended benefit cost analysis which could make possible the analysis of non-market goods such as the food security value and the environmental public value of paddy fields. To carry out the study, the publication on the guideline for economic analysis of agricultural projects were reviewed and consulted and for the post evaluation of the land consolidation and on-farm development project, field survey in Jeongja area were made for the feasibility study of the project by new method. According to the initial project plan, Jeongja land consolidation and on-farm development project has 96ha of benefit area and the project was started in 1989 and completed in the spring, 1990. The total project costs were amounted to 1,052 million won and the annual project benefits were estimated at 135.4 million in 1989 constant market prices. On the other hand, the newly estimated project benefits as a part of post evaluation of the project were amounted to 602.1 million won including all the benefits from the market and non-market commodities of the project as mentioned above column. The original IRP(Internal rate of return) of the project was estimated at 15.81%. On the other hand, the IRR of the post evaluation of the project was amounted to 16.83%. In case of including the benefit from the environment public function of paddy field, the SRR(Social Rate of Return) was reached to 38.81% and when we added the benefit from food security of the project, the SRR showed very high rate as 46.41%. In conclusion, the project were verified socio-economically feasible and environmentally sustainable considering the above decision making criteria.

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Secure Training Support Vector Machine with Partial Sensitive Part

  • Park, Saerom
    • Journal of the Korea Society of Computer and Information
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    • v.26 no.4
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    • pp.1-9
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    • 2021
  • In this paper, we propose a training algorithm of support vector machine (SVM) with a sensitive variable. Although machine learning models enable automatic decision making in the real world applications, regulations prohibit sensitive information from being used to protect privacy. In particular, the privacy protection of the legally protected attributes such as race, gender, and disability is compulsory. We present an efficient least square SVM (LSSVM) training algorithm using a fully homomorphic encryption (FHE) to protect a partial sensitive attribute. Our framework posits that data owner has both non-sensitive attributes and a sensitive attribute while machine learning service provider (MLSP) can get non-sensitive attributes and an encrypted sensitive attribute. As a result, data owner can obtain the encrypted model parameters without exposing their sensitive information to MLSP. In the inference phase, both non-sensitive attributes and a sensitive attribute are encrypted, and all computations should be conducted on encrypted domain. Through the experiments on real data, we identify that our proposed method enables to implement privacy-preserving sensitive LSSVM with FHE that has comparable performance with the original LSSVM algorithm. In addition, we demonstrate that the efficient sensitive LSSVM with FHE significantly improves the computational cost with a small degradation of performance.

Risk-Scoring System for Prediction of Non-Curative Endoscopic Submucosal Dissection Requiring Additional Gastrectomy in Patients with Early Gastric Cancer

  • Kim, Tae-Se;Min, Byung-Hoon;Kim, Kyoung-Mee;Yoo, Heejin;Kim, Kyunga;Min, Yang Won;Lee, Hyuk;Rhee, Poong-Lyul;Kim, Jae J.;Lee, Jun Haeng
    • Journal of Gastric Cancer
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    • v.21 no.4
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    • pp.368-378
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    • 2021
  • Purpose: When patients with early gastric cancer (EGC) undergo non-curative endoscopic submucosal dissection requiring gastrectomy (NC-ESD-RG), additional medical resources and expenses are required for surgery. To reduce this burden, predictive model for NC-ESD-RG is required. Materials and Methods: Data from 2,997 patients undergoing ESD for 3,127 forceps biopsy-proven differentiated-type EGCs (2,345 and 782 in training and validation sets, respectively) were reviewed. Using the training set, the logistic stepwise regression analysis determined the independent predictors of NC-ESD-RG (NC-ESD other than cases with lateral resection margin involvement or piecemeal resection as the only non-curative factor). Using these predictors, a risk-scoring system for predicting NC-ESD-RG was developed. Performance of the predictive model was examined internally with the validation set. Results: Rate of NC-ESD-RG was 17.3%. Independent pre-ESD predictors for NC-ESD-RG included moderately differentiated or papillary EGC, large tumor size, proximal tumor location, lesion at greater curvature, elevated or depressed morphology, and presence of ulcers. A risk-score was assigned to each predictor of NC-ESD-RG. The area under the receiver operating characteristic curve for predicting NC-ESD-RG was 0.672 in both training and validation sets. A risk-score of 5 points was the optimal cut-off value for predicting NC-ESD-RG, and the overall accuracy was 72.7%. As the total risk score increased, the predicted risk for NC-ESD-RG increased from 3.8% to 72.6%. Conclusions: We developed and validated a risk-scoring system for predicting NC-ESD-RG based on pre-ESD variables. Our risk-scoring system can facilitate informed consent and decision-making for preoperative treatment selection between ESD and surgery in patients with EGC.

An Empirical Analysis of Influencing Factors toward Public Transportation Demand Considering Land Use Type Seoul Subway Station Area in Seoul (토지이용유형별 서울시 역세권 대중교통 이용수요 영향인자 실증분석)

  • Oh, Young Taek;Kim, Tae Ho;Park, Je Jin;Rho, Jeong Hyun
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.29 no.4D
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    • pp.467-472
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    • 2009
  • Even if Seoul City administration improved its public transportation service, transportation model share in seoul has not been increased. Subway user is also decreasing. Therefore, policy transition into TOD(Transit Oriented Development) should be applied in oder to enhance subway modal share. This paper develops a influencing model by using variables of transportation demand and supply. In addition, it provides major influencing factors for users in subway station area and level of transportation supply based on the analysis results. The results show that: first, cluster analysis presents that traffic pattern is proved to be different according to land use characteristics(residence, non-residence); second, main transportation variables such as transferring distance, the number of bus stop, the number of short distant bus lines, and the number of bicycle are more supplied in residential area compared to non-residential areas; third, the number of lines, bus dispatching interval, operating time, and distance between subway stations are more supplied in non-residential areas than residential areas. All in all, the results will be useful for providing priority of considerations in case of decision-making on public transportation policy in subway station area.

Inventory Investment and Business Cycle: Asymmetric Dynamics of Inventory Investment over the Business Cycle Phases (재고투자와 경기변동: 재고투자 동학의 경기국면별 비대칭성)

  • Seo, Byeongseon;Jang, Keunho
    • Economic Analysis
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    • v.24 no.3
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    • pp.1-36
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    • 2018
  • When it comes to explaining the relationship between inventory investment and business fluctuations, the production smoothing theory and the stock-out avoidance theory take contradictory stances. Decision-making related to inventory investments of corporations is thought to be influenced by both motives, but the relative sizes or directions of their respective influences can differ depending upon the phase of the business cycle. Against this backdrop, this paper differs from existing studies in that it theoretically tests the relative significances of the production smoothing and stock-out avoidance motives in the inventory investment dynamics, while placing its analytical focus on determining the existence and patterns of the asymmetric dynamics of inventory investment over the business cycle phases. To this end this paper sets up a non-linear model that is expanded from the existing linear inventory investment model, and checks whether its predictive power is better than that of the existing model. The results of analysis confirm the nature of the asymmetric dynamics of inventory investment over the business cycle phases. A stock-out avoidance motive appears but there is no significant production smoothing motive in boom times. In downturns, in contrast, the stock-out avoidance motive is insignificant, but a quality of asymmetric dynamics in which changes in inventory cause the deepening of recessions, due to the non-convexity of production costs proposed by Ramey (1991), is detected. This paper confirms that a model considering the asymmetric dynamics of inventory investment can have better predictive power than one that does not consider it, through within-sample and out-of-sample predictions and various predictive power tests. These research results are expected to be useful for economic forecasting, through their enhancement of the understandings of the inventory investment dynamics and of the nature of its business cycle destabilization.

Consumer's Pro-environmental Behavior Relating to Clothing by the Style of Purchase Behavior (소비자구매행동유형에 따른 의류제품의 환경친화적 소비행동 분석)

  • Huh, Kyun-Gok
    • Journal of Families and Better Life
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    • v.25 no.2 s.86
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    • pp.23-36
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    • 2007
  • Or this research, it was investigated the differences in the pro-environmental behaviors in purchase, use and management, and disposal of clothing by socio-demographic characteristics and other variables. In addition, it was classified Korean consumers into several comsumer groups based on the different purchase behavior style, and then investigated the difference among these consumer groups in purchase, use and management, and disposal of clothing in light of the pro-environmental behavior. The following is the summary of the main results. First, consumers with high income and ha41g a lot of clothing were less likely to purchase used-clothing while consumers who were non-married and in low-income status were more likely to rent clothing. In additions, female, married consumers, and consumers with less-educated were more likely to manage their clothing frequently. Second, it was classified consumers into several groups based on the different purchase behavior style, these were "rational purchasing", "saving-money purchasing", "regretting for their purchasing", and "over-purchasing". Third, "saving-money purchasing" group showed a high expenditure rate in the purchase of used-clothing but a low rate in "over-purchasing" group. The frequency of management of clothing was the highest in the group of "over-purchasing" and the next in the group of "saving-money purchasing". The group of "over-purchasing" were more likely to show irrational decision-making style, manage and disposal their clothing frequently, "saving-money purchasing" purchased used-clothing frequently, and the level of management of clothing were less in the group of "regretting for their purchasing".

Spatial Ground Zoning and Analysis of Geotechnical Characteristics Considering Tunnel Interface (터널 간섭에 따른 지반의 공간 구역화 및 지반공학적 특성 분석)

  • Jeon, Je-Sung;Kim, Yong-Seong;Kim, Ki-Young
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.9 no.4
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    • pp.252-260
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    • 2005
  • In this research, case studies considering tunnel interface were conducted for zoning the ground into spatial area having similar geotechnical characteristics and estimating geotechnical properties for each area. The site for analysis consists of banded biotite gneiss, biotite schist and granite gneiss with spatial non-homogeneity, and for that reason weathering and fault zone were distributed with large scale. It's important thing to consider spatial ground zone and their geotechnical properties properly into stability analysis at design and construction stage. Also, in this studies, these analysis works are very useful for further decision making process by stability analysis.

A Statistical Testing of the Consistency Index in Analytic Hierarchy Process (계층적 의사결정론에서 일관성 지수에 대한 통계적 검정)

  • Lee, Jong Chan;Jhun, Myoungshic;Jeong, Hyeong Chul
    • The Korean Journal of Applied Statistics
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    • v.27 no.1
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    • pp.103-114
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    • 2014
  • Significant research has been devoted to the consistency index of the Analytic Hierarchy Process(AHP) from several perspectives. Critics of the consistency index in AHP state that the critical value of consistency index depends on an average of the random index based simulation study using a 9 scale comparison matrix. We found that the distribution of the consistency index followed the skew distribution according to the dimension of the comparison matrix based on a simulation study with a 9 scale comparison matrix. From the simulation study, we suggest a consistency index quantile table to assist the decision-making process in AHP; in addition, we can approximate the distribution of the consistency index to the gamma distribution under the limited assumptions.

Factors Influencing Acceptance of Hedonic Ubiquitous Services (헤도닉 유비쿼터스 서비스의 수용에 영향을 미치는 요인에 관한 연구)

  • Yoo, Ho-Sun;Kim, Min-Yong;Kwon, Oh-Byung
    • The Journal of Society for e-Business Studies
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    • v.17 no.1
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    • pp.1-21
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    • 2012
  • Conventional studies on technology acceptance have focused on information technology for utilitarian value and hence based on 'theory of reasoned action'. Correspondingly, the studies depend on perceived usefulness and perceived ease of use as rational decision making elements. However, in ubiquitous society, innovative technologies are applied to non-task area, as well as task-oriented area. Therefore, users are more influenced by affective factors than cognitive factors in causing their usage intention. In line with those discussions, we cannot make sure that the conventional technology acceptance model could fully explain the current u-service acceptance phenomenon. Hence, to overcome the limitations of the prior technology acceptance studies, we propose an amended TAM which includes one hedonic factor and two factors on ubiquitous computing technology : ubiquity and intelligence.