• Genomics & Informatics
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• v.17 no.3
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• pp.28.1-28.9
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• 2019

Bar-code (tag) microarrays of yeast gene-deletion collections facilitate the systematic identification of genes required for growth in any condition of interest. Anti-sense strands of amplified bar-codes hybridize with ~10,000 (5,000 each for up-and down-tags) different kinds of sense-strand probes on an array. In this study, we optimized the hybridization processes of an array for fission yeast. Compared to the first version of the array (11 ㎛, 100K) consisting of three sectors with probe pairs (perfect match and mismatch), the second version (11 ㎛, 48K) could represent ~10,000 up-/ down-tags in quadruplicate along with 1,508 negative controls in quadruplicate and a single set of 1,000 unique negative controls at random dispersed positions without mismatch pairs. For PCR, the optimal annealing temperature (maximizing yield and minimizing extra bands) was 58℃ for both tags. Intriguingly, up-tags required 3× higher amounts of blocking oligonucleotides than down-tags. A 1:1 mix ratio between up- and down-tags was satisfactory. A lower temperature (25℃) was optimal for cultivation instead of a normal temperature (30℃) because of extra temperature-sensitive mutants in a subset of the deletion library. Activation of frozen pooled cells for >1 day showed better resolution of intensity than no activation. A tag intensity analysis showed that tag(s) of 4,316 of the 4,526 strains tested were represented at least once; 3,706 strains were represented by both tags, 4,072 strains by up-tags only, and 3,950 strains by down-tags only. The results indicate that this microarray will be a powerful analytical platform for elucidating currently unknown gene functions.

• Journal of the Institute of Convergence Signal Processing
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• v.3 no.4
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• pp.67-73
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• 2002

There have been increased concerns on mobile stratospheric communication system(SCS) for the purpose of advanced service of personal and high speed communication systems. In fact, this SCS is considered and studied for IMT-2000 service by ITU. Although, it is important to make accurate channel model for prediction of the SCS performance, there is no measured channel data in this system. Thus, in this paper, we estimate the performance of SCS bye use of channel model provided by Corazza(2) and modified by You(3). And also, the effects of channel codings on system performance are analyzed by deriving bit error performance based on realistic Rician log-normal fading channel models. The performance results are divided into three kinds of areas with three kinds of elevation angles 20$^\cire$, 45$^\cire$, and 80$^\cire$. And also the effects of forward error correction channel codings on system performance with Hamming(7,4), HCH( IS,7) and convolutional code of constraint length 3 and code rate R=1/2.

• Food Science of Animal Resources
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• v.36 no.3
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• pp.319-325
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• 2016

This study was conducted to determine the residual amount of veterinary drugs such as meloxicam, flunixin, and tulathromycin in animal products (beef, pork, horsemeat, and milk). Veterinary drugs have been widely used in the rearing of livestock to prevent and treat diseases. A total of 152 samples were purchased from markets located in major Korean cities (Seoul, Busan, Incheon, Daegu, Daejeon, Gwangju, Ulsan and Jeju), including Jeju. Veterinary drugs were analyzed by liquid chromatography-tandem mass spectrometry according to the Korean Food Standards Code. The resulting data, which are located within 70-120% of recovery range and less than 20% of relative standard deviations, are in compliance with the criteria of CODEX. A total of five veterinary drugs were detected in 152 samples, giving a detection rate of approximately 3.3%; and no food source violated the guideline values. Our result indicated that most of the veterinary drug residues in animal products were below the maximum residue limits specified in Korea.

• Journal of the Korea Society of Computer and Information
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• v.11 no.6 s.44
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• pp.113-123
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• 2006

Flash memory has been increasingly used in handhold devices not only for data storage, but also for code storage. Because NAND flash memory only provides sequential access feature, a traditionally accepted solution to execute the program from NAND flash memory is shadowing. But, shadowing has significant drawbacks increasing a booting time of the system and consuming severe DRAM space. Demand paging has obtained significant attention for program execution from NAND flash memory. But. one of the issues is that there has been no effort to bound demand paging cost in flash memory and to analyze the worst case performance of demand paging. For the worst case timing analysis of programs running from NAND flash memory. the worst case demand paging costs should be estimated. In this paper, we propose two different WCRT analysis methods considering demand paging costs, DP-Pessimistic and DP-Accurate, depending on the accuracy and the complexity of analysis. Also, we compare the accuracy butween DP-Pessimistic and DP-Accurate by using the simulation.

• Geomechanics and Engineering
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• v.2 no.2
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• pp.141-156
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• 2010

In the framework of meshfree methods, a new methodology is developed based on radial point interpolation method (RPIM). This methodology is applied to a one-dimensional contaminant transport modelling in the saturated porous media. The one-dimensional form of advection-dispersion equation involving reactive contaminant is considered in the analysis. The Galerkin weak form of the governing equation is formulated using 1D meshfree shape functions constructed using thin plate spline radial basis functions. MATLAB code is developed to obtain the numerical solution. Numerical examples representing various phenomena, which occur during migration of contaminants, are presented to illustrate the applicability of the proposed method and the results are compared with those obtained from the analytical and finite element solutions. The proposed RPIM has generated results with no oscillations and they are insensitive to Peclet constraints. In order to test the practical applicability and performance of the RPIM, three case studies of contaminant transport through the landfill liners are presented. A good agreement is obtained between the results of the RPIM and the field investigation data.

• Journal of the Korea Institute of Military Science and Technology
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• v.13 no.2
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• pp.296-303
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• 2010

The term "spoofing" refers to the transmission of counterfeit signals to provide undetectable falsification of GPS service. A spoofing can be accomplished using information from open literature which defines the signal format and the data structure. Spoofing is intended either to produce erroneous navigation solutions or saturate the processor of the victim receiver. The GPS receiver has no way to get rid of the effect of a spoofing because GPS receivers for civil service do not have an anti-spoofing scheme. This paper analyzes the spoofing characteristics, spoofing methods and environment conditions. And the spoofing effects on GPS receiver are analyzed in detail using the designed software-based spoofer and the Nordnav receiver.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.25 no.8B
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• pp.1333-1340
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• 2000

This paper shows that the Kronecker sequence, the rapid acquisition spreading code, can be used in packet wireless data communication systems. The general properties of the Kronecker sequence such as construction and correlation characteristics are described, and it is shown that the Kronecker sequence can use a partial-period correlation for a faster acquisition. Based on above Properties, it can be expected that the Kronecker sequence can be used in packet communication systems because the probability of false alarm for the Kronecker sequence is lower and flatter(that is, less sensitive to Ec/No variations) than that for the PN sequence under the assumption that both sequences have the same acquisition time.

• Journal of Wellbeing Management and Applied Psychology
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• v.6 no.3
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• pp.1-11
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• 2023

Purpose: This research aims to facilitate a smooth transition from KCD-8 to ICD-11 through the study of ICD-11. Research design, data and methodology: Skilled Health Information Managers (HIMs) in Korea performed manual mapping and conducted a study of the code structure of ICD-11 chapters 11 and 12. Results: When comparing the granularity between ICD-11 and KCD-8, 58.1% of ICD-11 codes showed higher granularity, and 38.6% had similar granularity. The granularity of the circulatory system was higher than that of the respiratory system. When comparing the KCD-8 codes mapped by ICD-11 with the total 924 KCD-8 codes, it was found that about 50% of KCD-8 codes were not mapped to ICD-11. This means that 50% of diseases in the KCD-8 do not have individual codes as they did in ICD-11. Conclusions: ICD-11 demonstrated high granularity, indicating its effectiveness in describing cutting-edge medical technology in modern society. However, we also observed that some diseases were removed from KCD-8, while others were added to ICD-11. To ensure smooth statistics transition from KCD8 to ICD-11, especially for leading domestic diseases, integrated management, including the preparation of KCD-9 reflecting ICD-11 and ICD-11 training, will be necessary through the analysis of new codes and the removal of codes.

• The Journal of Economics, Marketing and Management
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• v.8 no.2
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• pp.13-17
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• 2020

Purpose: In modern corporate management, the establishment of a crisis management system that minimizes damage through measures used to respond to corporate crises is no longer an option. The importance of corporate reputation and brand asset management in modern enterprise management cannot be overemphasized and negative events that might arise from a number of different causes can cause brand crises. Research design, data and methodology: More than half of the questionnaire respondents were female (252 or 53%). More than a fourth of the respondents were aged 20 (122 or 26%) and the number of married participants was 196 (41%). Of the participants, 32% (153) had graduated from college. Only 18% (87) were employees and the monthly household income was 121. In this study, we conducted factor analysis in order to extract the variables that may enhance the explanation capability of each variable. For the method of factor extraction, an Eigen value of at least 1 was used as was factor loading. An analysis was performed using the Cronbach's alpha coefficient to verify the reliability of the measurement scale. Results: First, the analysis of the impact of the social responsibility activities on brand image revealed that the social, economic, philanthropic, ethical, and environmental responsibility activities significantly affected brand image, but legal responsibility activities were not statistically significant. Second, the analysis of the impact of brand image on loyalty showed that brand image had a significant impact on loyalty. Third, the analysis of the impact of social responsibility activities on loyalty showed that they had a significant impact on loyalty. Conclusions: The pro-social enterprise image is not only a brand asset that can be shared, but also a heavy proposition followed by a corresponding social responsibility, it will have to practice transparent corporate management based on clear principles through the establishment of various systems and the implementation of a strict code of conduct within the enterprise.

• The Journal of Korean Medicine
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• v.43 no.3
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• pp.27-35
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• 2022

Objectives: The purpose of this study is to investigate and analyze Korean domestic patents on aconiti ciliare radix and to identify the trend of aconitum tuber technology. Methods: To analyze the patent, a combinations of words such as "aconitum" or "korean aconite root" were used in search engine Kipris(www.kirpis.or.kr). The patents of aconiti ciliare radix were analyzed in three ways: year trend analysis, internatonal patent classification (IPC) code analysis related to content classification, and patent registration status analysis. Results: Among the patents found in the search results, 17 patents with significant contents were analyzed. Results showed that, first, patents were steadily registered until 2018, but recently there has been no new patent registration. Second, there were many patents related to efficacy verification and decoction method, and the number of IPC codes related to them was also high. Third, there are five patents maintaining the registration status, and they are patents related to the aconiti ciliare radix extraction method, toxicity removal, and combination method. Conclusions: In this study, the domestic patents of aconiti ciliare radix were analyzed. The analysis results of this study are expected to be exploited as basic data for the development of Korean medicine analgesics with fewer side effects by suppressing tuber toxicity and the creation of new medical technologies.