• The Journal of Internal Korean Medicine
• /
• v.24 no.4_2
• /
• pp.967-974
• /
• 2003

Recurrent Aphthous Stomatitis(RAS) is inflammatory ulcerative condition of the oral mucosa. The lesions of RAS are self-limited and persist for 1 to 2 weeks, resolved with or without scarring and recurred after periods of remission. It is known that nicotine may protect oral mucosa from aphthous ulcers by keratinization of the oral mucosa. After quitting smoking, a stroke patient who suffered from RAS, used to relapse into RAS unless he didn't gargle with nicotine extract water. We diagnosed his case as heat in the stomach and treated with Chungwie-San(Qingwei-San). After medication with Chungwie-San, RAS was subsided and he stopped smoking during admission period.

• Proceedings of the Zoological Society Korea Conference
• /
• 2001.10a
• /
• pp.178.2-178
• /
• 2001

No Abstract, See Full Text

• Proceedings of the Zoological Society Korea Conference
• /
• 2000.10a
• /
• pp.176.2-176
• /
• 2000

No Abstract, See Full Text

• Journal of dental hygiene science
• /
• v.15 no.6
• /
• pp.753-760
• /
• 2015

Although nuclear factor of activated T cell (NFAT) plays a key role in inflammation, its anti-inflammatory effects and mechanism of action in periodontitis are still unknown. This study aimed to identify the effects of NFAT on the proinflammatory mediators activated by lipopolysaccharide (LPS) plus nicotine stimulation in human periodontal ligament cells (hPDLCs). The production of nitric oxide (NO) and prostaglandin $E_2(PGE_2)$ was evaluated using Griess reagent and an enzyme immunoassay, respectively. The expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2) and NFAT proteins was evaluated by Western blot analysis. LPS plus nicotine synergistically induced the production of NO and $PGE_2$ and increased the protein expression of iNOS, COX-2 and NFAT. Treatment with an NFAT inhibitor blocked the LPS plus nicotine-stimulated NO and $PGE_2$ release as well as the expression of iNOS and COX-2. Our data suggest that the LPS plus nicotine-induced inflammatory effects on hPDLCs may act through a novel mechanism involving the action of NFAT. Thus, NFAT may provide a potential therapeutic target for the treatment of periodontal disease associated with smoking and dental plaque.

• Research in Community and Public Health Nursing
• /
• v.20 no.2
• /
• pp.251-258
• /
• 2009

Purpose: The study aimed to compare characteristics associated with smoking and smoking cessation of those who had succeeded in smoking cessation. Methods: Data were collected from January to June, 2008. The subjects were 9,819 smokers who were registered at the smoking cessation clinic of public health centers in Incheon. Four characteristics (demographic, health promotion, smoking, smoking cessation) were compared between 6-week (short-term) and 6-month (long-term) success groups. Results: There was a significant difference between the 6-week and 6-month success groups for smoking cessation in demographic characteristics (gender, age, job, social security), health promotion (BMI, alcohol dependency, BP), smoking (first smoking age, smoking duration, expiration CO concentration, nicotine dependency), and smoking cessation (attempt to quit smoking, reason for smoking cessation, information source for registration). Conclusion: The group of short-term smoking cessation success was younger than the other. Also, short-term success group was of lower socioeconomic class than the other. The 6-month success group had a larger number of attempts to quit smoking. Therefore, smoking cessation policy should be focused more on younger people and those in lower socioeconomic status. These groups should be given advice on smoking cessation motives and more frequent counseling for smoking cessation.

• Korean Journal of Health Education and Promotion
• /
• v.22 no.1
• /
• pp.55-71
• /
• 2005

Purpose: The purpose of this study was to find out what are the major motivations of middle and high school students to quit attempts and stay as non-smokers. Method: Data was collected through focus group interviews with 3 groups(15 students), and was analyzed according to Morgan and Kruger(1998)'s analytic method. Results: We identified 6 categories of motivations for Smoking Cessation. They include perceptions of negative consequences of smoking on health, influences in significant others, being ashamed of oneself, drop of academic achievements, narrowness in interpersonal relationships, determining priorities for a student. Although 'perceptions about negative health consequences' was one of the most significant motivation of smoking cessation for adolescents, participants did not know the seriousness of nicotine addiction. Moreover, their contents of motivations were different from those of adults such as responsibility for their family, decreasing curiosity about smoking and test of self willingness. Also most of them were extrinsic motivations and related to their highly competitive school life. Conclusion: To conclude, considering the results of our analysis, smoking cessation programs should be carefully developed to more effectively help adolescents quit and stay away from smoking.

• Korean Journal of Health Education and Promotion
• /
• v.29 no.3
• /
• pp.1-14
• /
• 2012

Objectives: The purpose of this study was to determine if smoking cessation programs (SCPs) are effective for adults through a systematic review of the results of such programs in large randomized controlled trials (RCTs). Methods: The PICO (Patient, Intervention, Comparator, Outcome) strategy was established, 1,160 literature from domestic and foreign electronic databases was reviewed, and 22 references were selected based on the inclusion and exclusion criteria. The quality of each reference was evaluated using the Scottish Intercollegiate Guidelines Network tool, and meta-analysis was carried out. Results: The SCPs were significantly effective for adult smokers. Smoking cessation counseling, education, and smoking cessation medications such as nicotine patch were more effective than the other interventions. However, the results showed short-term effects (within six months), and differences were observed among the SCPs. For the outcome measures for SCPs, the abstinence rate of seven days was mainly used, but differences were identified between the CO level and the cotinine-verified abstinence rate of smoking cessation. Conclusions: For a smoking cessation program for adult smokers, the strength of the evidence of the program's effectiveness in RCTs that provide the identified intervention strategies should be considered.

• Preventive Nutrition and Food Science
• /
• v.8 no.4
• /
• pp.372-376
• /
• 2003

The efficacy of a medicinal herb tea (MHT) for assisting smoking cessation and for reducing withdrawal symptoms was evaluated by a placebo controlled subjective test in 100 male smokers. The MHT group experienced less craving for the taste of tobacco, and was more successful at quitting smoking. Among the subjects continuing to the final stage, 23 subjects (38.3 %) who took the MHT and 2 subjects (10.0 %) who took the placebo tea succeeded in quitting smoking. In the group taking MHT, urinary cotinine concentration increased during the first 2 weeks and then greatly decreased from weeks 2 to 4. The urinary cotinine concentration in the MHT group at week 0 was 38.6 mol/L but decreased to 24.5 mol/L by the end of week 4. MHT also reduced withdrawal symptoms, a frequent reason for failure in reducing or quitting smoking. The effects of the herbal tea on smoking cessation and withdrawal symptoms may be attributed to increased metabolism of nicotine and other effects of unidentified components of the herbal ingredients.

• Journal of Korean Academy of Nursing
• /
• v.35 no.7
• /
• pp.1362-1370
• /
• 2005

Purpose: The purpose of this study was to identify the degree of attaining a smoking cessation goal when an agreement on means to achieve smoking cessation among male college student smokers was established. Method: This study was planned as a nonequivalent control group non-synchronized design and the sample was divided into an agreement group and a comparison group by convenience sampling in a college of G city. The data was analysed with SPSS Win10.0 using a Likelihood $x^2-test$, Odds ratio, Paired t-test and ANCOVA. Result: The theory that the degree of smoking cessation will be higher in the agreement group than the Comparison group was rejected (${\delta}$ = 2.567, p = .055). The theory that nicotine dependency will be lower in the agreement group than the comparison group was supported (F = 3.965, P = .049); however, the theory that the number of cigarettes smoked per day will be lower in the agreement group than the comparison group was rejected (F = 1.342, p = .252). Conclusion: It has been shown that an agreement on means to achieve smoking cessation goals is a key factor to success in quitting smoking.

• Korean Journal of Occupational Health Nursing
• /
• v.14 no.1
• /
• pp.24-33
• /
• 2005

Purpose: This cross-sectional study was to find out smoking condition, smoking related knowledge and attitudes of white color workers to provide baseline data which were to develope smoking cessation programs. Methods: The subjects were 303 workers in G-city. Data were collected from July 1st to Aug. 31st 2003 by self-reported questionnaire. Data were analyzed by descriptive statistics, t-test, ANOVA, and Duncan's multiple comparison test, using SAS-pc 8.0 version. Results: Average age of the laborers was 32.3 years, and 50.7% of male were smoking currently, and 2.4% of female were so. Starting age of smokers was average 20.1 and smoking period was average 12.4 years. Majority of smokers smoked more than one pack of cigarettes in a day. Average points of nicotine dependency was 3.9 out of 10 and 12.5% were more than 7. Those who wanted to 'quit smoking very soon' and 'decided to quit smoking right now' were 29.1%. But those who got any helps and advices from professional experts in smoking cessation were 6.4%. 83.5% of the smokers had tried to quit smoking but failed due to their stress(44.6%), lack of will(36.6%) etc. Laborers knowledge related smoking score were average 11points out of 15, and attitudes were average 75.7points out of 125. Smokers showed significantly low knowledge(p=.012), and more allowing attitudes(p=.001). Conclusions: The smoking cessation programs for the workers should consist of stress management skills, and strengthened willingness. And should be run the program for those who want to 'quit smoking very soon' and 'decided to quit smoking right now' first of all.