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THE EFFECT OF IMPLANTATION OF HYDROXYAPATITE IN THE FRESH EXTRACTION SOCKETS ON THE RESIDUAL RIDGE RESORPTION IN INDUCED DIABETIC RABBITS (당뇨병 유발 토끼에서 발치 후 Hydroxyapatite 충전이 잔존 치조제 흡수에 미치는 영향)

  • Bae Jeong-Sik;Chung Moon-Kyu
    • The Journal of Korean Academy of Prosthodontics
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    • v.30 no.4
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    • pp.541-564
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    • 1992
  • The purpose of this experiment was to study the effect of implantation of the dense hydroxyapatite (HA) granules$(Apaceram^{(R)})$ in the fresh extraction sockets on the residual ridge resorption in normal and induced diabetic rabbits. Sixty-four white rabbits, weighing 3.0kg, were utilized in this study and they were divided into four group : group 1-sixteen normal rabbits without filling HA granules, group 2-sixteen normal rabbits with filling HA granules, group 3-sixteen diabetic rabbits without filling HA granules, group 4-sixteen diabetic rabbits with filling HA granules. HA granules were filled immediately after extraction in the extraction sockets of the mandibular left 1st, 2nd, and 3rd molar in group 2 and 4, and no HA granules were filled in group 1 and 3. The calculation of residual ridge resoption was done at 4th week, 8th week, 12th week, and 16th week after surgery, and histologic examination was performed to study healing process at 2nd week, 4th week, 8th week, and 16th week after surgery. The results were as follows : 1. The amount of residual ridge resorption was largest in group 3, and smallest in group 2 in every interval. There was no statistically significant difference between group 1 and 4. 2. In all groups, the amount of residual ridge resorption was high until 4th week after surgery, but the rate of residual ridge resolution slowly decreased after 4th week 3. There was more active healing process in group 1 and 2 than in group 2 and 4. 4. According to filling of HA granules, there was no difference in the amount of new bone formation, but direct contact could be observed between newly formed bone and HA granules in group 2 and 4. 5. Group 1 and 3 showed marked bone resorption and adipose marrow from 8th-16th week after surgery, but group 2 and 4 did not show maeked bone resolution, and showed fibrous tissue and a little adipose tissue among trabeculae from 8th week.

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Perspectives on the Landscape Characteristics and Management Scheme of Sacred Dangsan Forest in Singi-ri, Namwon-si as an Agricultural Heritage (농업유산으로서 남원시 신기리 당산숲의 경관 특성 및 관리방안 고찰)

  • Choi, Jai-Ung;Kim, Dong-Yeob;Yoon, Soon-Duck;Kwak, Min-Jeong
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.34 no.3
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    • pp.115-123
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    • 2016
  • In this study, the landscape characteristics of the sacred Dangsan forests at Singi-ri, Namwon-si were investigated as an agricultural heritage, and the management scheme for revitalization of the village was introduced. FAO established the term of 'GIAHS' (Globally Important Agricultural Heritage Systems) for conservation of each country's farmland, unique agricultural landscape, and cultural diversity. The Ministry of Agriculture, Food and Rural Affairs of Korea evaluates that the Agricultural Heritage is a new means and potential for rural development. Dangsan forest, a traditional village forests of rural Korea is a representative 'agricultural heritage' with a history of more than several hundred years of Dangsan ritual. The Dangsan forests were closely linked with paddy fields. This forest was composed of two Dangsan forests, and one Bibo forest. Especially, the Dangsan forest 2 was established on the mounding with 395m in length and 15m in width. Although, most of Dangsan forests do not have accurate records about forest establishment, this forest has retained a stone monument that illustrated the history of the forest. These aspects of Singi-ri's Dangsan forest indicated clear difference and characteristics compared to other ones. This Dangsan forest has been left alone from the public attention. The Dangsan forest at Singi-ri need to be recognized for their valuable landscape characteristics. By linking the Dangsan forest with 'Jirisan trail', the trail path will lead people to the agricultural heritage at Singi-ri. Enhancing the management scheme will contribute to revitalize the village.

Measuring of Anti-oxidant Activity and Skin Improvement Effect using Adenophora remotiflora leaf (모시대잎을 이용한 항산화 및 피부개선 효과 측정)

  • Lee, Min-Jung;Lee, Yeon-Hee;Kim, Ae-Jung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.1
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    • pp.239-246
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    • 2013
  • The purpose of this study was to find out the potential of the Mosidae(Adenophora remtriflora) leaf, one of the natural ingredients, for the cosmetics by measuring their antioxidant functions and skin improving effects. The result of the phytonutrient of the Mosidae leaf test shows, that the heat extract of Mosidae leaf DPPH has 9% higher ability than Ethanol extract.(p<0.05), but significant a difference was not found between the hydroxyl Radical of Mosidae leaf heat extract (65.22%) and Ethanol extract(63.50%). Mosidae leaf heat extract(40.82mg/mL) has much lower polyphenol compound than Ethanol extract(47.90mg/mL)(p<0.05). A clinical test of Mosidae leaf powder pack was performed for a group of 16 middle aged women(age between 35-60) from October 20 to November 17, 2011. Control group was used on the right cheek, and test group was used on left cheek for comparison. The procedure was twice a week for 4 weeks to identify and grade level of moisture, roughness, pore size and spot. After 4 weeks of testing, there were significant improvements in moisture enhancement and spot(p<0.05), subtle change in roughness and the size of the pores. Therefore, we confirmed skin improvement effect of Mosidae leaf as new cosmetic material.

Automated Functional Morphology Measurement Using Cardiac SPECT Images (SPECT 영상을 사용한 기능적 심근형태의 자동 계측법 개발)

  • Choi, Seok-Yoon;Ko, Seong-Jin;Kang, Se-Sik;Kim, Chang-Soo;Kim, Jung-Hoon
    • Journal of radiological science and technology
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    • v.35 no.2
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    • pp.133-139
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    • 2012
  • For the examination of nuclear medicine, myocardial scan is a good method to evaluate a hemodynamic importance of coronary heart disease. but, the automatized qualitative measurement is additionally necessary to improve the decoding efficiency. we suggests the creation of cardiac three-dimensional model and model of three-dimensional cardiac thickness as a new measurement. For the experiment, cardiac reduced cross section was obtained from SPECT. Next, the pre-process was performed and image segmentation was fulfilled by level set. for the modeling of left cardiac thickness, it was realized by applying difference equation of two-dimensional laplace equation. As the result of experiment, it was successful to measure internal wall and external wall and three-dimensional modeling was realized by coordinate. and, with laplace formula, it was successful to develop the thickness of cardiac wall. through the three-dimensional model, defects were observed easily and position of lesion was grasped rapidly by the revolution of model. The model which was developed as the support index of decoding will provide decoding information to doctor additionally and reduce the rate of false diagnosis as well as play a great role for diagnosing IHD early.

Reconstruction of Congenital Absence of Vagina using Vulvoperineal Fasciocutaneous Flap: A Case Report (외음회음 근막피부피판을 이용한 선천성 질결여증의 재건례)

  • Kim, Mi-Sun;Kim, Chul-Han;Lee, Yong-Sek;Kang, Sang-Gue;Tark, Min-Sung
    • Archives of Plastic Surgery
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    • v.37 no.6
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    • pp.831-834
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    • 2010
  • Purpose: Congenital absence of the vagina is a rare case. It occurs as a result of Mullerian duct aplasia or complete androgen insensitivity syndrome. The reconstructive modality includes skin graft, use of intestine and various methods of flap. We report a patient who underwent vulvoperineal fasciocutaneous flap to reconstruct congenital absence of the vagina, while the external genitalia and ovaries are normal. Methods: A 26-year-old woman presented with vaginal agenesis. Under general anesthesia, a U-shaped incision was made between the urethral meatus and the anus. The new vaginal pocket was created up to the level of the peritoneal reflection between the urinary structures and the rectum. Next, the vulvoperineal fasciocutaneous flaps were designed in a rectangular fashion. Flap elevation was begun at the lateral margin which the adductor longus fascia was incised and elevated, and the superficial perineal neurovascular pedicle was invested by the fascial layer. The medial border was then elevated. A subcutaneous tunnel was created beneath the inferior of the labia to rotate the flaps. The left vulvoperineal flap was rotated counterclockwise and the right was rotated clockwise. The neovaginal pouch was formed by approximating the medial and lateral borders. The tubed neovagina was then transposed into the cavity. Results: In 3 weeks, the vaginal canal remained supple After 6 weeks, the physical examination showed normalappearing labia majora and perineum with an adequate vaginal depth. A year after the operation, the patient had a 7 cm vagina of sufficient width with no evidence of contractures nor fibrous scar formation. The patient was sexually active without difficulty. Conclusion: Although many methods were described for reconstruction of vaginal absence, there is not a method yet to be approved as a perfect solution. We used the vulvoperineal fasciocutaneous flap to reconstruct a neovagina. This method had a following merits: a single-stage procedure, excellent flap reliability, the potential for normal function, minimal donor site morbidity and no need for subsequent dilatation, stents, or obturators. We thought that this operation has a good anatomic and functional results for reconstruction of the vagina.

transprosthetic Pressure Gradient after aortic Valve Replacement with Small Sized Prostheses (작은 기계 판막을 이용한 대도액 판막 치환술 후 판막 전후 압력차)

  • Hwang, Kyung-Hwan;Park, Kay-Hyun;Cha, Dae-Won;Jun, Tae-Gook;Park, Pyo-Won;Chae, Hurn
    • Journal of Chest Surgery
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    • v.33 no.2
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    • pp.146-150
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    • 2000
  • background: The prognosis after an aortic valve replacment can be affected significantly by the transprosthetic pressure gradient which is determined mainly by the size of the patients body and the prosthesis used. We analyzed the hemodynamic feature of two relatively new prosthese the ATS and the evensized Medtronic-Hall(M-H) valves by measuring the transprosthetic pressure gradient in the cases where small sizes (23mm or smaller) were used. Material and method: There were 94 patients who received whom aortic valve replacement with prosthesis smaller than 23 mm from October 1994 to June 1998. In these patients the transprosthetic pressure gradient clalculated from the pressure half time during postoperative Dopper echocardiographic examination was compared between the prostheses of different sizes. The body surface area of each patient was also taken into consideration. result: The mean pressure gradient and body surface area in each group were 21.7$\pm$10.2 mmHg and 1.52$\pm$0.14m2 in ATS 19mm 11.4$\pm$6.5 mmHg and 1,57$\pm$0.20m2 in M-H 20mm 15.2$\pm$6.3 mmHg and 1.54$\pm$0.13m2 in ATS 21mm 9.3$\pm$2.5 mmHg and 1.63 $\pm$0.14m2 in M-H 22 mm and 12.9$\pm$5.3 mmHg and 1.69$\pm$0.13m2 in ATS 23mm. Conclusion: The 19mm ATS prosthesis showed significant trasprosthetic pressure gradient which is similar to the values previously reported with other bileaflet prosthesesm Close follow-up was needed in terms of exercise capacity and change in left ventiricular geometry. In patients with small aortic valve annulus the 20mm M-H valve is recomendable as an alternative to 19mm bileaflet valves because it has less pressure gradient with similar outer diameter.

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Surgical Correction of Tetralogy of Fallot in Adults over 20 Years of Age (20세이상 성인 팔로사징후의 완전교정술에 관한 임상적 고찰)

  • 류완준;강종렬;조창욱;김정철;구본일;이홍섭;김창호;우건화;이신영
    • Journal of Chest Surgery
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    • v.29 no.11
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    • pp.1197-1201
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    • 1996
  • From October, 1987 to December, 1995, nine patients underwent total correction of tetralogy of Fallot in adults over 20 years of age. There were 5 male and 4 female patients aged from 22 to 42 years(mean, 29.6 years). Three patients were in New York Heart Association(NYHA) functional class II, and 6 patients in class III. The hemoglobin values ranged from 10.8 to 20.7 gm/㎗ (average, l5.6gm/㎗). The preoperative clinical features were as follows: cyanosis, 8 patients; dyspnea on exertion, 6 patients; clubbing of fingers, 5 patients; frequent upper respiratory infection, 3 patients. At the operation both infundibular and valvular stenosis were present in all patients. Reconstruction of right ventricular outflow tract(RVOT) using Goretex was required in 7 patients, and transannular patching with Goretex in 2 pateints. Left pulmonary angioplasty with pericardium was done in 2 patients. No hospital deaths occurred. Four of 9 patients(44.4%) had postoperative low cardiac output syndrome, and postoperative bleeding in 5. One patient required reoperation due to residual ventricular septal defect and tricuspid regurgitation 3 months after the first operation. The mean follow-up period was 25 months, range 11 to 77 months. All was asymptomatic and in NYHA class I. We suggest that advanced age is not contraindication to surgery in tetralogy of Fallot, and tetralogy of Fallot in adults could be operated on due to low mortality.

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Identity of Spirometra theileri from a Leopard (Panthera pardus) and Spotted Hyena (Crocuta crocuta) in Tanzania

  • Eom, Keeseon S.;Park, Hansol;Lee, Dongmin;Choe, Seongjun;Kang, Yeseul;Bia, Mohammed Mebarek;Ndosi, Barakaeli Abdieli;Nath, Tilak Chandra;Eamudomkarn, Chatanun;Keyyu, Julius;Fyumagwa, Robert;Mduma, Simon;Jeon, Hyeong-Kyu
    • Parasites, Hosts and Diseases
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    • v.57 no.6
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    • pp.639-645
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    • 2019
  • In the present study, a Spirometra species of Tanzania origin obtained from an African leopard (Panthera pardus) and spotted hyena (Crocuta crocuta) was identified based on molecular analysis of cytochrome c oxidase I (cox1) and NADH dehydrogenase subunit I (nad1) as well as by morphological observations of an adult tapeworm. One strobila and several segments of a Spirometra species were obtained from the intestine of an African male leopard (Panthera pardus) and spotted hyena (Crocuta crocuta) in the Maswa Game Reserve of Tanzania. The morphological characteristics of S. theileri observed comprised 3 uterine loops on one side and 4 on the other side of the mid-line, a uterine pore situated posterior to the vagina and alternating irregularly either to the right or left of the latter, and vesicular seminis that were much smaller than other Spirometra species. Sequence differences in the cox1 and nad1 genes between S. theileri (Tanzania origin) and S. erinaceieuropaei were 10.1% (cox1) and 12.0% (nad1), while those of S. decipiens and S. ranarum were 9.6%, 9.8% (cox1) and 13.0%, 12.6% (nad1), respectively. The morphological features of the Tanzania-origin Spirometra specimens coincided with those of S. theileri, and the molecular data was also consistent with that of S. theileri, thereby demonstrating the distribution of S. theileri in Tanzania. This places the leopard (Panthera pardus) and spotted hyena (Crocuta crocuta) as new definitive hosts of this spirometrid tapeworm.

Development of a Fall-prevention Exercise Program for Elderly People in Community (지역사회 노인낙상예방을 위한 운동 프로그램 개발 및 예비조사)

  • Lee, Seon Heui;Bak, Won-Sook;Shin, Gyeyoung;Lee, Kyung-Sook;Lim, Kyung-Choon;Kim, Minju;Lee, Inok;Choi, Hee Kwon;Park, Mi Sung;Bae, Sun Hyoung;Yu, Jae Sun;Chung, Jae Hee;Youn, In Sook;Eun, Young;Choi, Mi-Kyung
    • Journal of muscle and joint health
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    • v.27 no.1
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    • pp.61-70
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    • 2020
  • Purpose: The purpose of this study was to develop a new fall-prevention exercise intervention for the community-dwelling elderly and to examine the effects of program. Methods: A total of 7 older adults were participated in a 10-week fall-prevention exercise intervention (1 day per a week in community centers, 2 days per a week in a home). The exercise program consisted of warming-up, extension exercises, muscle strength exercises, balance exercises, and finishing exercise. Data were collected before the exercise and after 10 weeks of exercise. In this study, muscle strength of lower limbs was measured by 10 times of standing up and sitting on a chair. Static balance was measured by one-leg standing, and dynamic balance was measured by 6 meter walking. Results: After a 10-week exercise program, muscle strength of lower limbs (t=4.18, p<.05), statical balance were significantly improved (left leg, t=-3.11, p<.05; right leg, t=-4.56, p<.05). Seven of 11 items measuring fear of falls were significantly decreased (p<.05), and dynamic balance tended to be improved (p=.117). Conclusion: This result suggests that evidence-based, fall-prevention exercise program can improve muscle strength, static and dynamic balance, and fear of falling in the community living elderly.

Development of the New Hybrid Evolutionary Algorithm for Low Vibration of Ship Structures (선박 구조물의 저진동 설계를 위한 새로운 조합 유전 알고리듬 개발)

  • Kong, Young-Mo;Choi, Su-Hyun;Song, Jin-Dae;Yang, Bo-Suk
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.16 no.6 s.111
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    • pp.665-673
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    • 2006
  • This paper proposes a RSM-based hybrid evolutionary Algorithm (RHEA) which combines the merits of the popular programs such as genetic algorithm (GA), tabu search method and response surface methodology (RSM). This algorithm, for improving the convergent speed that is thought to be the demerit of genetic algorithm, uses response surface methodology and simplex method. The mutation of GA offers random variety to finding the optimum solution. In this study, however, systematic variety can be secured through the use of tabu list. Efficiency of this method has been proven by applying traditional left functions and comparing the results to GA. It was also proved that the newly suggested algorithm is very effective to find the global optimum solution to minimize the weight for avoiding the resonance of fresh water tank that is placed in the after body area of ship. According to the study, GA's convergent speed in initial stages is improved by using RSM method. An optimized solution is calculated without the evaluation of additional actual objective function. In a summary, it is concluded that RHEA is a very powerful global optimization algorithm from the view point of convergent speed and global search ability.