• 동의신경정신과학회지
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• 제28권4호
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• pp.381-390
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• 2017

Objectives: The purpose of this study is to study the personality traits and cognitive characteristics of the Sasang constitution by comparing the Personality Test and Neuropsychological Test. Methods: A total of 121 subjects were analyzed with the results of a Two Step Questionnaire for the Sasang Constitution Diagnosis (TS-QSCD). Among them, the Personality Tests (SPQ, EPQ, TCI) and the Neuropsychological Tests (A-VLT, CPM, Stroop-CWIT, WCST) were processed and analyzed for Soyangin, Taeeumin, Soeumin. Results: 1. In the results of the SPQ, the Soyangin showed a significantly higher score than did the Taeeumin and Soeumin in Behavior, Emotionality, Cognition, as well as the Total Score. The SPQ-C score and SPQ-T were significantly higher for Soyangin, Soeumin and Taeeumin, in that order. 2. In the results of the EPQ, the Soyangin showed a significantly higher score than did the Taeeumin and Soeumin in Extraversion - introversion. Soeumin showed a significantly higher score than did the Soyangin and Taeeumin in Neuroticism. Soyangin also showed a significantly higher score than Taeeumin in Venturesomeness. 3. For the results of the TCI, the Soyangin showed a significantly lower score than did Taeeumin and Soeumin in Harm-Avoidance, but a significantly higher score in Persistence and Self-Directedness. Soyangin and Taeeumin showed a significantly higher score than did Soeumin for the total score of Self-Directedness+Cooperativeness. 4. The results of the Computerized Neuropsychological Tests (A-VLT, CPM, Stroop-CWIT, WCST) showed no significant differences between the Sasang constitution. Conclusions: The EPQ, TCI score showed significant differences between the Sasang constitution. But the Computerized Neuropsychological Tests developed to evaluate cognitive abilities did not show differences between the constitutional individuals and showed limitations as a research tool. Further studies are needed to devise a research method for ascertaining the cognitive behavioral characteristics of the Sasang constitution.

• 동의신경정신과학회지
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• 제26권2호
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• pp.131-142
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• 2015

Objectives: The purpose of this study is to evaluate the personality traits and cognitive characteristics of the Sasang constitution by comparing the Eysenck Personality Questionnaire (EPQ), Temperament and Character Inventory (TCI), Continuous Performance Test (CPT) and Stroop Test. Methods: One hundred and six healthy subjects (age 20 to 40) were analyzed; 45 Taeeumin, 30 Soyangin and 31 Soeumin. The Sasang constitution was diagnosed by a sasang constitutional medicine specialist based on the results of a Two Step Questionnaire for Sasang Constitution Diagnosis (TS-QSCD), the external appearance, temperament and symptoms. The results of the EPQ, TCI, CPT and Stroop Test were compared between Sasang constitutions. Results: Among the seven dimensions of EPQ, Taeeumin and Soyangin scored significantly higher than Soeumin in Extraversion. Soyangin scored significantly higher than Soeumin in Impulsiveness. Among the four temperament dimensions of TCI, Taeeumin and Soyangin scored significantly higher than Soeumin in novelty seeking, reward dependence and persistence. Soeumin scored significantly higher than Taeeumin and Soyangin in harm avoidance. Among the three character dimensions of TCI, Soyangin scored significantly higher than Taeeumin in self transcendence. The results for CPT showed no significant differences between sasang constitutions. Taeeumin had a significantly higher color score in the stroop test than Soeumin. Conclusions: The personality tests showed significant differences between Sasang constitutions, but the neuropsychological test did not show any differences. Further studies should be performed to identify neuropsychological differences between Sasang constitutions.

• 동의생리병리학회지
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• 제27권5호
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• pp.553-562
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• 2013

This study was performed to develop cold-heat and deficiency-excess pattern identification for dementia, as well as for standard Korean medicine diagnosis and treatment. Five experts comprised of 4 neuropsychiatrists of Korean medicine and 1 statistician to develop cold-heat and deficiency-excess pattern identification for dementia. We searched studies about pattern identification and selected 507 articles using Oasis search terms provided by the KIOM. As a result, 10 pattern identification research study were recruited. Moreover, we analyzed neuropsychological assessments for dementia that evaluate Behavioral and Psychological Symptoms of Dementia (BPSD) and cognitive function using experts conferences and we selected neuropsychological instruments using pattern identification. Six cold patterns, six heat patterns, ten deficiency patterns, and four excess patterns were identified according to the cold-heat and deficiency-excess pattern identification of dementia. We selected the Caregiver-Administered Neuropsychiatric Inventory and the Korean Mini-Mental State Examination as neuropsychological assessments of dementia, which examine behavioral symptoms and cognitive function, suspectively. We formed positive and negative correlation between Korean medicine pattern identification and neuropsychological assessments for dementia. We developed and suggested a forecast module of pattern identification for dementia. But, it is necessary to perform additional clinical trials to verify its validity and accuracy.

• 정신신체의학
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• 제6권2호
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• pp.136-146
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• 1998

Objectives : This study was performed to evaluate the effects of PTSD on memory function, to investigate the difference of memory function between PTSD and non-PTSD patients, and to identify major variables correlated to PTSD scale and Memory Assessment Scale. Methods: The authors used PTSD-scale(Mississippi scale and Combat Exposure Scale) for measuring PTSD severity. And, Beck Depression Inventory was also used. Memory assessment scale was assessed by well trained psychologist. Thirty one Vietnam veterans who had been hospitalized were collected consecutively. These patients were evaluated by psychiatrists with interview and measurement for fifteen months since March, 1997. The collected data were analyzed by SPSS and the stastistic methods used for analysis Chi-square, t-test, and Pearson's correlation. Results : 1) There were significant differences in short-term memory and verbal memory between PTSD and non-PTSD in Vietnam veterans. 2) Mississippi scale and Combat Exposure Scale were negatively correlated to short-term memory and verbal memory(Pearson's correlation). 3) Religion status was a significant variable between PTSD and non-PTSD in Vietnam veterans. 4) There is no significant difference in visual memory and total memory scale between PTSD and Non-PTSD in Vietnam veterans Conclusions : Neuropsychological changes were found in the posttraumatic stress disorder. There were significant differences in short-term memory and verbal memory between PTSD and non-PTSD in Vietnam veterans. Mississippi scale and Combat Exposure Scale were negatively correlated to short-term memory and verbal memory. We suggest that neuropsychological test might be used for an objective assessment of patients with the combat related PTSD and be considered helpful in the assessment of patients with the diagnosis. And we also suggest rehabilitation strategies would be used to compensate for memory deficits in PTSD patients.

• Journal of Korean Neurosurgical Society
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• 제54권5호
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• pp.390-398
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• 2013

Objective : We determined whether the relationship between the neuropsychological performance of patients with mild traumatic brain injury (TBI) and their psychopathological characteristics measured by disability evaluation are interrelated. In addition, we assessed which psychopathological variable was most influential on neuropsychological performance via statistical clustering of the same characteristics of mild TBI. Methods : A total of 219 disability evaluation participants with mild brain injury were selected. All participants were classified into three groups, based on their psychopathological characteristics, via a two-step cluster analysis using validity and clinical scales from the Minnesota Multiphasic Personality Inventory (MMPI) and Symptom Checklist-90-revised (SCL-90-R). The Korean Wechsler Adult Intelligence Scale (K-WAIS), Korean Memory Assessment Scale (K-MAS) and the Korean Boston Naming Test (K-BNT) were used to evaluate the neurocognitive functions of mild TBI patients. Results : Over a quarter (26.9%) experienced severe psychopathological symptoms and 43.4% experienced mild or moderate psychopathological symptoms, and all of the mild TBI patients showed a significant relationship between neurocognitive functions and subjective and/or objective psychopathic symptoms, but the degree of this relationship was moderate. Variances of neurocognitive function were explained by neurotic and psychotic symptoms, but the role of these factors were different to each other and participants did not show intelligence and other cognitive domain decrement except for global memory abilities compared to the non-psychopathology group. Conclusion : Certain patients with mild TBI showed psychopathological symptoms, but these were not directly related to cognitive decrement. Psychopathology and cognitive decrement are discrete aspects in patients with mild TBI. Furthermore, the neurotic symptoms of mild TBI patients made positive complements to decrements or impairments of neurocognitive functions, but the psychotic symptoms had a negative effect on neurocognitive functions.

• The Korean Journal of Pain
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• 제22권1호
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• pp.28-32
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• 2009

Background: Complex regional pain syndrome (CRPS) is characterized by severe neuropathic pain and disability, which can result in psychological and behavioral dysfunction. The goal of the present study was to evaluate neurocognitive disability, and to assess the relationship between clinical variables and neuropsychological features in CRPS patients. Methods: We investigated the neuropsychological features of 15 CRPS I patients. The neuropsychological tests that we made comprised of a full intelligence quotient, memory quotient, trail-making test A, trail-making test B (TMT-B), and MMPI (Minnesota multiphasic personality inventory). Results: The results showed severe disability in performance on TMT-B. There was no significant correlation between specific cognitive variables and MMPI scales. Conclusions: Decreased performance on TMT-B which shows mental flexibility in the prefrontal lobe exists independently from depressive disorders in CRPS patients.

• 수면정신생리
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• 제6권2호
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• pp.143-148
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• 1999

목 적: 지각 장애가 어떤 뇌의 부위와 기능에 장애가 있을 때 발생되는지를 알아보기 위해 정신과와 뇌손상 환자에서 신경심리 검사와 지각 장애와 관계성을 조사하였다. 방 법: 정신과 환자 69명, 뇌손상 환자 50명, 총 119명에서 Halstead Reitan 신경 심리 검사와 K-WAIS, MMPI를 시행하였다. MMPI 항목 중 지각 장애와 관계되는 9개 항목에서 산출된 점수와 신경심리 검사의 결과와의 상관 관계를 조사하였다. 또 정신과 환자에서 지각 장애 점수가 높은 지각 장애군 21명과 지각 장애가 없는 지각 장애 17명을 t-test로 비교하였다. 결 과: 뇌손상 환자군에서 지각 장애가 전두엽 기능을 보는 범주화 검사, 선로 잇기 검사, 촉각 수행 검사, 손끝 숫자 쓰기 검사와 우측 반구 기능을 보는 촉각 수행 검사의 위치, 동작성 점수, 빠진곳 찾기, 차례 맞추기, 토막 짜기 등과 유의한 상관 관계를 보였다. 또 피질하 기능을 보는 숫자 상징, 산수, 숫자 외우기와 유의한 상관 관계를 보였다. 정신과 환자의 높은 지각 장애군은 우측 반구 편측화 지수와 빠진 곳 찾기, 토막 짜기와 같은 우측 반구 기능에서 유의한 차이가 있었고, 또 이해, 어휘, 공통성과 같은 좌측 반구 기능에서도 유의한 차이가 있었다. 결 론: 지각 장애는 전두엽, 우측 반구, 피질하 구조의 기능과 깊은 연관성을 가지고 발생이 되며, 정신과 환자군에서는 좌측 반구의 기능도 영향을 주는 것으로 생각된다.

• 생물정신의학
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• 제24권3호
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• pp.149-154
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• 2017

Objectives This study investigated associations between symptom severity and neurocognitive functions in patients with major depressive disorder using comprehensive neuropsychological tests. Methods Ten patients with low depression (LD) and 22 patients with high depression (HD) participated. Symptom severity was determined by both the Beck Depression Inventory and the Hamilton Depression Rating Scale. Additionally, anxiety was measured by the Korean version of the State-Trait Anxiety Inventory (STAI-KYZ). Ten subtests of the Korean-Wechsler Adult Intelligence scale (K-WAIS), Stroop test, the word/design fluency tests were administered to assess cognition. Results The LD and HD groups did not differ in any of cognitive measures but anxiety level. Namely, the HD group obtained significantly higher scores on the state (U = 29.50, p < 0.01) and trait (U = 28.50, p < 0.001) anxiety scales than the LD group. A significant interaction effect between trait anxiety and depression severity was observed on the picture arrangement subtest of the K-WAIS [F (1, 27) = 5.09, p < 0.05]. Conclusions Cognitive deficits observed in patients with major depressive disorder may be related to other factors rather than current symptom severity. Trait anxiety possibly moderates the effect of current symptom severity on social judgment in these patients.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제26권3호
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• pp.226-235
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• 2015

Objectives : The purpose of this study was to examine the factor structure of the Adolescent Personality Assessment Inventory (PAI-A) in a standardized adolescent sample using exploratory factor analysis (EFA) and confirmatory factor analysis (CFA). Methods : For this purpose, three models about factor structure of the PAI-A were explored with EFA in 490 adolescents and then were evaluated with CFA in 268 young offenders. Results : The results showed that the five factor model was considered to be most appropriate for factor structures of the PAI-A in EFA. However, none of the factor models were appropriate for the factor structures of the PAI-A in CFA. Conclusion : These findings suggest that the "five factor model" is thought to explain the PAI-A the best, but further studies are needed.

• 정신신체의학
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• 제5권1호
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• pp.89-96
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• 1997

SLE 환자들에서 인지기능의 장애가 있는지를 알아보기 위해서 신경정신과적 병력이 없는 내과 외래 SLE 환자 20명과 정상 대조군 20명을 대상으로 전산화 신경인지기능 검사인 Vienna test system을 시행하고 이를 인지기능에 영향을 미칠 수 있는 임상 변인들과의 연관성을 분석하여 다음과 같은 결과를 얻었다. 1) SLE 환자군과 정상 대조군의 신경인지기능 검사의 각 항목 비교 인식력 검사항목에서 SLE 환자군은 정상 대조군에 비해 정확하게 응답한 반응수가 적었으며 '예'와 '아니오' 중 '아니오'를 정확하게 반응한 수도 적었다. 또한 '예'와 '아니오'에 대해 각각 정확한 반응을 하는 평균 반응시간이 길었으며 검사소요 시간도 길었다. 주의력 검사항목에서는 SLE 환자군이 정상 대조군에 비해 정확하게 응답한 반응수가 적었고, 평균 반응시간이 길었다. 그러나, corsi단기 기억력 검사항목에서는 시각적 단기 기억력 범위와 정확하게 맞춘 총 응답수에서 두군 간에 유의한 차이가 없었다. 표준도형 지능검사항목에서 SLE 환자군은 정상 대조군에 비해 정확하게 응답한 반응수가 적었다. 신경행동학적 인지상태 검사중 기억력 항목에서 SLE 환자군은 정상 대조군에 비해 유의하게 낮은 점수를 보였다. 2) 신경인지기능의 각 항목과 환자군의 연령, 교육연한, SLE 질환 활성도(SLE Disease Activity Index), 우울 증상의 정도, 항 ds-DNA항체. 보체 C3/C4, 스테로이드의 용량 등의 임상 변인들과의 상관관계를 비교하였을 때 통계적으로 유의하지 않았다. 이상의 결과에서 질환 활성도가 낮은 SLE환자들은 과거 신경정신과적 증상의 병력이 없고 병의 이환 기간이 비교적 짧음에도 불구하고 인지기능의 장애를 나타내었다. 그리고 이는 기타 장기의 침범으로 인한 비특이적 영향이 아닌 중추신경계의 침범에 의한 것으로 보이며 우울정도나 스테로이드 용량에 영향을 받지 않는 것으로 생각된다.