• Journal of Oriental Neuropsychiatry
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• v.21 no.2
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• pp.201-214
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• 2010

Y$\grave{u}$zh$\grave{e}$ng(鬱證) comes from obstruction of qi by stress. The patient has depressed mood, irritable sign, chest discomfort, costal pain, angry state or some strange feeling on the throat. Oh-Ji-Sang-Seung(五志相勝) therapy is base on the theory of interrelation in five elements in oriental medicine. The contents of Oh-Ji-Sang-Seung(五志相勝) therapy include five subjugations of five emotions. Anxiety subjugates fear(思勝恐), fear subjugates joy(恐勝喜), joy subjugates pity(喜勝悲), pity subjugates anger(悲勝怒), and anger subjugates anxiety(怒勝思). Forgiveness program is a kind of psychological therapies to decrease the degree of anger and it is included in Oh-Ji-Sang-Seung(五志相勝) therapy. In this case, a female patient, 50 years old, who suffered from Y$\grave{u}$zh$\grave{e}$ng(鬱證) with chest discomfort, irritable sign, easily angry state, depressed mood, hot flush, insomnia. We used Oh-Ji-Sang-Seung(五志相勝) therapy besides herbal medication, acupuncture to her condition got improved. Therefore we reported it for the treatment.

• Journal of Oriental Neuropsychiatry
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• v.24 no.spc1
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• pp.37-46
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• 2013

Objectives : The Hwabyung Research Center of The Korean Society Of Oriental Neuropsychiatry has attempted to develop the 'Clinical Guidelines for Hwabyung'. Methods : The Hwabyung Research Center constructed a committee of experts and advisory group. Relevant literature was collected and evaluated in order to find out effective Pharmacotherapy (Herbal medicine), acupuncture and moxibustion, and cupping of Hwabyung. Results : We found some evidences that proved the effectiveness of Pharmacotherapy (Herbal medicine), acupuncture and moxibustion, and cupping in the treatment of Hwabyung. 1) We recommend Pharmacotherapy (Herbal medicine), acupuncture and moxibustion, cupping, psychotherapy and management, other therapeutic approaches and education for Hwabyung. 2) Pharmacotherapy (Herbal medicine) should be determined according to the pattern identification of Korean medicine. Further, the prescription should be cost-effective, safe and have no side effects. Also, the interaction between Herbal and Western drugs should be considered carefully. 3) There are general acupuncture, scalp acupuncture, Pharmacopuncture, Sa-am acupuncture as well as acupuncture treatments for Hwabyung. 4) Moxibustion and cupping are useful, relieving various somatic symptoms of Hwabyung. Conclusions : Pharmacotherapy (Herbal medicine), Acupuncture and Moxibustion, Cupping for Hwabyung were studied. We hope that the 'Clinical Guidelines for the Treatment of Hwabyung' are helpful for oriental medical doctors and patients.

• Journal of Oriental Neuropsychiatry
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• v.13 no.2
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• pp.21-39
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• 2002

Objectives : This study is designed to evaluate the psychological characteristics of Sasang Constitution(Origin and Nature & Emotion Group) by MBTI. Methods : 200 people were tested by QSCCII(Origin and Nature & Emotion Group) and MBTI. It is analyzed by ANOVA, Frequency, Crosstabulation, Duncan & Scheffe Post Hoc Tests. Results : 1. The number of Soyangin was 73, Soeumin was 49, Taeumin was 50, Not classified was 28 in Origin group and Soyangin was 114, Soeumin was 28, Taeumin was. 26 in Nature & Emotion group. When we evaluate QSCCII with 38 Nature & Emotion questionaires, the number of Soyangin are incresed compare to Origin Group. 2. The most three MBTI Types are Soyangin ISTJ, ISTP, ESTJ, Soeumin IJST, ISTP, INTJ, Taeumin ISTJ, ESTP, ESTJ, in Origin Group and Soyangin ISTJ, ESTJ, ISTP, Soeumin ISTJ, ISTP, INTJ, Taeumin ISTJ, ESTP, ISFP in Nature & Emotion Group. There is no significant difference between Origin and Nature & Emotion Group in ststistics. 3. Soeumin & Taeumin tended to be introverted, judging types in Origin and Nature & Emotion Group. Soeumin tended to be intuition type in Nature & Emotion Group. Conclusion : We have not significant differences on peculiarity of sasang constitution compared to MBTI between Origin and Nature & Emotion Group in ststistics.

• Anxiety and mood
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• v.2 no.2
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• pp.94-100
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• 2006

Objective : This study was designed to examine the volumetric abnormality of orbitofrontal cortex (OFC) and its change after 2 years of pharmacotherapy in obsessive compulsive disorder (OCD) patients. Method : Volumetric magnetic resonance imaging studies were conducted in 15 OCD patients and 13 normal volunteers. For 2 years, all patients took at least one serotonin reuptake inhibitor and atypical antipsychotics were used as an augmentation therapy in most patients. The follow-up MRI studies were conducted after the pharmacotherapy and OFC volumes were measured by the manual region of interest method. Results : Bilateral OFC volumes of 15 OCD patients were significantly greater than those of the normal volunteers before the treatment. After 2 years of the treatment, significant decrease was observed in bilateral OFC volumes of OCD patients to the extent that left OFC volume of OCD patients was not different from that of the normal volunteers. Conclusion : This finding suggests that OFC is directly related to the pathophysiology of obsessive compulsive disorder.

• Journal of Oriental Neuropsychiatry
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• v.17 no.3
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• pp.67-75
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• 2006

This Study is attempted to analyze Minnesota Multiphasic Personality Inventory responses to Vertigo patients and remedial value of Oriental medicine treatment. Methods: 24 Vertigo patients and 28 control group were tested by MMPI and QSCCII. It is analyzed by cluster analysis, one-way ANOVA, chi-square test, t-test, Duncan method is used as ex-post test. Results and Conclusions: 1. The MMPI scores of Vertigo patients were elevated in Hs, Hy clinical scales, 1-3 profile type, it is profile of conversional neurosis. In this case body condition where the psychological problem will get conversion is a notable feature. 2. All of the profiles can be classified three types of profile. Group 1(33.3%) showed 1-3-2 profile type and elevated Pt. scale, suggesting mainly depressive neurosis in the department of neuropsychiatry. Group 2 (37.5%) showed a normal profile. Group 3(29.2%) showed 1-3 profile type it is profile of conversional neurosis. With this result it is indicated that 62.5% Vertigo patients are related to emotional difficulties. 3. There was to a remedial value for the Vertigo patients, before treating from VAS score 10.00 after treating at VAS score 4.13. From this study, we know the possibility the Oriental medicine register remedial value for the Vertigo patients.

• Journal of Oriental Neuropsychiatry
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• v.12 no.1
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• pp.11-27
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• 2001

In oriental medicine, from old times, psychological therapy has been regarded as physical therapy that has been inseparable from psychological therapy. The major objects for oriental psychological therapy is human emotions. Human emotions can be put in the seven feelings(七精) that include Joy(善), Anger(怒), Grief(思), Pity(悲), Fear(恐), Surprise(驚). The seven feelings are connected with human physiology. If each of the seven feelings if excessive, human physiology loses its valance. So the seven feelings are major causes of diseases. The specific character of oriental neuropsychiatry is to make use of the seven feelings in clinical treatment. These oriental neuropsychiatry therapies are performed through consultation with the patient. Of these therapies, Oh-Ji-Sang-Seung(五志相勝療法) is based on the theo교 of interrelation in five elements(metal, wood, water, fire, and earth) in oriental medicine. Specially the sequential subjugations of the five emotions are applied. The contents of Oh-Ji-Sang-Seung(五志相勝療法) include five subjugations of five emotions. Anxiety subjugates fear(思勝恐), fear subjugates joy(恐勝喜), joy subjugates pity(喜勝悲), pity subjugates anger(悲勝怒) and anger subjugates anxiety(怒勝思). The psychological therapy of Oh-Ji-Sang-Seung(五志相勝療法) can be applied in all area of neuropsychiatry. These days, many mental diseases such as Panic Disorder, Depression Somatoform disorders, and negative symptoms of Schizophrenia have been improved by Oh-Ji-Sang-Seung(五志相勝療法) therapy. Here, we present the treatment cases applied Oh-Ji-Sang-Seung(五志相勝療法) therapy in oriental medicine quoted from old oriental books and the latest treatment cases. Moreover, we hope that many oriental therapist will treat many different patients with mental disorders by Oh-Ji-Sang-Seung(五志相勝療法) therapy.

• Journal of Oriental Neuropsychiatry
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• v.15 no.1
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• pp.65-76
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• 2004

Alzheimer's disease(AD) is a geriatric dementia that is widespread in old ages. In the future AD will be the largest problem in public health service. From old times, much medicines have been used for treatment of dementia, but there is no medicine having obvious effects. AD is one of brain retrogression disease. So we studied on herbal medicine that have a relation for brain retrogression. From old times, in oriental medicine, senile disease such as dementia and AD is treated by exclusion of Tan(痰). But Vascular Dementia(VsD) is due to YuXue(瘀血). So in recent studies, Hua Xue Hua Yu(活血化瘀) medicine is used for precautionary and medical treatment. We studied on the effects for anti-Alzheimer in pCT105-induced neuroblastoma cell lines by Hyeolbuchukeo-tang(HCT). As the results of this study, in HCT group, the apoptosis in the nervous system is inhibited, the repair against the degeneration of Neuroblastoma cells by CT105 expression is promoted. These results indicate that HCT possess strong inhibitory effect of apoptosis in the nervous system and repair effect against the degeneration of neuroblastoma cells by CT105 expression.

• Journal of Oriental Neuropsychiatry
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• v.15 no.1
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• pp.187-196
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• 2004

Objective: This clinical study was aimed to search the therapeutic effects of Oriental Medicine in Submaxillary Tremor. In Oriental Medicine, the tremor of the elder is caused by Gansinyinheo and Qihyeolyangheo. Besides, it has relation to liver, kidney, heart, and spleen according to Jangbu theory. On the basis of this theory, we performed various treatment on Submaxillary Tremor. Method: We carried out three people cases who are elder female-patients with Submaxillary Tremor. We treated them with Herbal medicine(Jihwangyeumjagami, Guibiondamtanggami), acupuncture(Ganjeonggyeok), and moxibustion on Baekhoi(GV20). Result and Conclusion: As the result of our treatment, Submaxillary Tremor was disappeared and some other symptoms were improved.

• Journal of Oriental Neuropsychiatry
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• v.17 no.3
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• pp.21-43
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• 2006

This study was designed to assess Effects of jingansikpungtanggagam-bang on Central Nerve System. Method : jingansikpungtanggagam-bang, a Korean traditional prescription, was evaluated for its anticonvulsant effect, hypnotic activity, analgesic action, anxiolytic effect, memory enhancement, and MAO inhibitory activity and detennined the content of neurotransmitter in brain by HPLC method. Result : 1. The extract increased potently anticonvulsant effect at 1g/kg by 5.6-fold extention of onset time against control group. 2. The extract increased hvrmsis at 500mg/kg by over twofold length of sleeping time compared to control. 3. The extract showed a significant analgesic effect with 86.0% inhibition on writhing frequency at 500mg/kg by phenylquinone-induced writhing test. 4. The extract inhibited dose-dependently the activity of monoamine oxidase in vitro. 5. This prescription increased the brain levels of serotonin and 5-hydroxyindoleacetic acid by 3.3% and 1.4%, respectively. 6. the extract exhibited the anxiolytic effect with 21.3% decrease of the immobility duration against control group. 7. the extract enhanced memory recovery on scopolamine-induced impairment of passive avoidance performance at 1g/kg pretreatment with 20.2% increase of latency time. Conclusion : The result sugguest that jiugansikpungtanggagam-bang can be used effectively as a sedative prescription in Korean traditional medicine.

• Journal of Oriental Neuropsychiatry
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• v.21 no.4
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• pp.123-135
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• 2010

Objectives : This study was performed to develop a standard instrument of oriental medical evaluation for dementia. Methods: The advisor committee on this study was organized by 17 neuropsychiatry professors of oriental medical colleges. The items and structure of the instrument were based on review of published literature. We took consultation twice from the advisor committee and we also took additional advices bye-mail. Results: We discriminated between bian-zheng and su-zheng from the answers of the advisor committee. We got the mean weight of each symptom and sign from the answers of the advisor committee. We got the final weight from the combination of the ratio of bian-zheng to the number of all answers of the advisor committee and mean weight. Conclusions : The instrument of oriental medical evaluation for dementia was developed through experts' discussion. If the validity and reliability of this instrument is confirmed through additional clinical trial. the instrument of oriental medical evaluation for dementia is expected to be applied to the subsequent research.