• 제목/요약/키워드: Neural tube defect

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조기학습정지를 이용한 원전 SG세관 결함크기 예측 신경회로망의 성능 향상 (A performance improvement of neural network for predicting defect size of steam generator tube using early stopping)

  • 조남훈
    • 전기학회논문지
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    • 제57권11호
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    • pp.2095-2101
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    • 2008
  • In this paper, we consider a performance improvement of neural network for predicting defect size of steam generator tube using early stopping. Usually, neural network is trained until MSE becomes less than a prescribed error goal. The smaller the error goal, the greater the prediction performance for the trained data. However, as the error goal is decreased, an over fitting is likely to start during supervised training of a neural network, which usually deteriorates the generalization performance. We propose that, for the prediction of an axisymmetric defect size, early stopping can be used to avoid the over-fitting. Through various experiments on the axisymmetric defect samples, we found that the difference bet ween the prediction error of neural network based on early stopping and that of ideal neural network is reasonably small. This indicates that the error goal used for neural network training for the prediction of defect size can be efficiently selected by early stopping.

원전 증기발생기 세관 결함 크기 예측을 위한 Bagging 신경회로망에 관한 연구 (A Study on Bagging Neural Network for Predicting Defect Size of Steam Generator Tube in Nuclear Power Plant)

  • 김경진;조남훈
    • 비파괴검사학회지
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    • 제30권4호
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    • pp.302-310
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    • 2010
  • 본 논문에서는 원자력 발전소 증기발생기 세관에 발생할 수 있는 결함의 크기측정에 사용되는 Bagging 신경회로망에 대한 연구를 수행하였다. Bagging은 부트스트랩(bootstrap) 샘플링에 기반을 둔 추정기 앙상블을 생성하는 방법이다. 증기발생기 세관의 결함 크기측정을 위하여 다양한 폭과 깊이를 갖는 4가지 결함패턴의 eddy current testing 신호를 생성하였다. 그 다음, 단일 신경회로망(single neural network; SNN)과 Bagging 신경회로망(Bagging neural network; BNN)을 구성하여 각 결함의 폭과 깊이를 추정하였다. SNN과 BNN 추정성능은 최대오차를 이용해서 측정하였다. 실험결과, 결함 깊이 추정시의 SNN과 BNN 최대오차는 0.117mm와 0.089mm 이었다. 또한, 결함 폭 추정 시에는 SNN과 BNN 최대오차는 0.494mm와 0.306mm 이었다. 이러한 실험결과는 BNN 추정성능이 SNN 추정성능보다 우수하다는 것을 보여준다.

Junctional Neural Tube Defect

  • Eibach, Sebastian;Pang, Dachling
    • Journal of Korean Neurosurgical Society
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    • 제63권3호
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    • pp.327-337
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    • 2020
  • Junctional neurulation represents the most recent adjunct to the well-known sequential embryological processes of primary and secondary neurulation. While its exact molecular processes, occurring at the end of primary and the beginning of secondary neurulation, are still being actively investigated, its pathological counterpart -junctional neural tube defect (JNTD)- had been described in 2017 based on three patients whose well-formed secondary neural tube, the conus, is widely separated from its corresponding primary neural tube and functionally disconnected from corticospinal control from above. Several other cases conforming to this bizarre neural tube arrangement have since appeared in the literature, reinforcing the validity of this entity. The cardinal clinical, neuroimaging, and electrophysiological features of JNTD, and the hypothesis of its embryogenetic mechanism, form part of this review.

Junctional Neurulation : A Junction between Primary and Secondary Neural Tubes

  • Kim, Kyung Hyun;Lee, Ji Yeoun
    • Journal of Korean Neurosurgical Society
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    • 제64권3호
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    • pp.374-379
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    • 2021
  • Recent case reports of junctional neural tube defect (JNTD) which is a peculiar type of spinal anomaly showing the functional disconnection of the primary and secondary neural tubes has risen interest in the process of junctional neurulation (the connection between the two neural tubes) during development. This article summarizes the clinical features of the JNTD and reviews the literature on the basic research on junctional neurulation.

원전SG 세관 결함크기 예측을 위한 신경회로망 구조에 관한 연구 (A Study on the Structure of Neural Network for Predicting Defect Size of Steam Generator Tube in Nuclear Power Plant)

  • 조남훈
    • 조명전기설비학회논문지
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    • 제24권1호
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    • pp.63-70
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    • 2010
  • 본 논문에서는 원자력발전소 증기세관 크기 예측을 위한 신경회로망 구조에 대해서 연구한다. 와류탐상 시험(ECT) 신호로부터 특징을 추출한 후, 결함크기 예측을 위해서 다층퍼셉트론 신경회로망을 이용한다. 결함크기 예측성능을 최대화하기 위해서는 신경회로망의 구조, 특히 은닉층 내의 뉴런의 개수를 신중히 결정하여야 한다. 본 논문에서는, 결함크기 예측을 위한 은닉층 내의 뉴런의 개수를 교차검증을 이용하여 매우 효과적으로 결정할 수 있음을 보인다.

Enhancement of Re-closure Capacity by the Intra-amniotic Injection of Human Embryonic Stem Cells in Surgically Induced Spinal Open Neural Tube Defects in Chick Embryos

  • Lee, Gun-Soup;Lee, Do-Hun;Kim, Eun-Young;Wang, Kyu-Chang;Lee, Won-Don;Park, Sepill;Lim, Jin-Ho
    • 한국동물번식학회:학술대회논문집
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    • 한국동물번식학회 2004년도 춘계학술발표대회
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    • pp.275-275
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    • 2004
  • To evaluate the potential of the stem cell therapy as a method for prenatal management of spinal open neural tube defect (ONTD), the influence of embryonic stem cells injected into the amniotic cavity on the re-closure capacity of spinal ONTD was investgated. Spinal neural tube was incised open for a length of 6 somites using chick embryos of Hamburger and Hamilton stage 18 or 19. (omitted)

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Bagging 방법을 이용한 원전SG 세관 결함패턴 분류성능 향상기법 (Classification Performance Improvement of Steam Generator Tube Defects in Nuclear Power Plant Using Bagging Method)

  • 이준표;조남훈
    • 전기학회논문지
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    • 제58권12호
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    • pp.2532-2537
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    • 2009
  • For defect characterization in steam generator tubes in nuclear power plant, artificial neural network has been extensively used to classify defect types. In this paper, we study the effectiveness of Bagging for improving the performance of neural network for the classification of tube defects. Bagging is a method that combines outputs of many neural networks that were trained separately with different training data set. By varying the number of neurons in the hidden layer, we carry out computer simulations in order to compare the classification performance of bagging neural network and single neural network. From the experiments, we found that the performance of bagging neural network is superior to the average performance of single neural network in most cases.

다중겹 교차검증 기법을 이용한 증기세관 결함크기 예측을 위한 신경회로망 성능 향상 (Improvement of Neural Network Performance for Estimating Defect Size of Steam Generator Tube using Multifold Cross-Validation)

  • 김남진;지수정;조남훈
    • 조명전기설비학회논문지
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    • 제26권9호
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    • pp.73-79
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    • 2012
  • In this paper, we study on how to determine the number of hidden layer neurons in neural network for predicting defect size of steam generator tube. It was reported in the literature that the number of hidden layer neurons can be efficiently determined with the help of cross-validation. Although the cross-validation provides decent estimation performance in most cases, the performance depends on the selection of validation set and rather poor performance may be led to in some cases. In order to avoid such a problem, we propose to use multifold cross-validation. Through the simulation study, it is shown that the estimation performance of defect width (defect depth, respectively) attains 94% (99.4%, respectively) of the best performance achievable among the considered neuron numbers.

신경회로망을 이용한 원전SG 세관 결함패턴 분류성능 향상기법 (Performance improvement of Classification of Steam Generator Tube Defects in Nuclear Power Plant Using Neural Network)

  • 조남훈;한기원;송성진;이향범
    • 전기학회논문지
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    • 제56권7호
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    • pp.1224-1230
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    • 2007
  • In this paper, we study the classification of defects at steam generator tube in nuclear power plant using eddy current testing (ECT). We consider 4 defect patterns of SG tube: I-In type, I-Out type, V-In type, and V-Out type. Through numerical analysis program based on finite element modeling, 400 ECT signals are generated by varying width and depth of each defect type. In order to improve the classification performance, we propose new feature extraction technique. After extracting new features from the generated ECT signals, multi-layer perceptron is used to classify the defect patterns. Through the computer simulation study, it is shown that the proposed method achieves 100% classification success rate while the previous method yields 91% success rate.

Overview of Secondary Neurulation

  • Catala, Martin
    • Journal of Korean Neurosurgical Society
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    • 제64권3호
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    • pp.346-358
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    • 2021
  • Secondary neurulation is a morphological process described since the second half of the 19th century; it accounts for the formation of the caudal spinal cord in mammals including humans. A similar process takes place in birds. This form of neurulation is caused by the growth of the tail bud region, the most caudal axial region of the embryo. Experimental work in different animal species leads to questioning dogmas widely disseminated in the medical literature. Thus, it is clearly established that the tail bud is not a mass of undifferentiated pluripotent cells but is made up of a juxtaposition of territories whose fate is different. The lumens of the two tubes generated by the two modes of neurulation are continuous. There seem to be multiple cavities in the human embryo, but discrepancies exist according to the authors. Finally, the tissues that generate the secondary neural tube are initially located in the most superficial layer of the embryo. These cells must undergo internalization to generate the secondary neurectoderm. A defect in internalization could lead to an open neural tube defect that contradicts the dogma that a secondary neurulation defect is closed by definition.