Enhancement of Re-closure Capacity by the Intra-amniotic Injection of Human Embryonic Stem Cells in Surgically Induced Spinal Open Neural Tube Defects in Chick Embryos

  • Published : 2004.06.01

Abstract

To evaluate the potential of the stem cell therapy as a method for prenatal management of spinal open neural tube defect (ONTD), the influence of embryonic stem cells injected into the amniotic cavity on the re-closure capacity of spinal ONTD was investgated. Spinal neural tube was incised open for a length of 6 somites using chick embryos of Hamburger and Hamilton stage 18 or 19. (omitted)

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