• Title/Summary/Keyword: Neural tube defect

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A performance improvement of neural network for predicting defect size of steam generator tube using early stopping (조기학습정지를 이용한 원전 SG세관 결함크기 예측 신경회로망의 성능 향상)

  • Jo, Nam-Hoon
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.57 no.11
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    • pp.2095-2101
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    • 2008
  • In this paper, we consider a performance improvement of neural network for predicting defect size of steam generator tube using early stopping. Usually, neural network is trained until MSE becomes less than a prescribed error goal. The smaller the error goal, the greater the prediction performance for the trained data. However, as the error goal is decreased, an over fitting is likely to start during supervised training of a neural network, which usually deteriorates the generalization performance. We propose that, for the prediction of an axisymmetric defect size, early stopping can be used to avoid the over-fitting. Through various experiments on the axisymmetric defect samples, we found that the difference bet ween the prediction error of neural network based on early stopping and that of ideal neural network is reasonably small. This indicates that the error goal used for neural network training for the prediction of defect size can be efficiently selected by early stopping.

A Study on Bagging Neural Network for Predicting Defect Size of Steam Generator Tube in Nuclear Power Plant (원전 증기발생기 세관 결함 크기 예측을 위한 Bagging 신경회로망에 관한 연구)

  • Kim, Kyung-Jin;Jo, Nam-Hoon
    • Journal of the Korean Society for Nondestructive Testing
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    • v.30 no.4
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    • pp.302-310
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    • 2010
  • In this paper, we studied Bagging neural network for predicting defect size of steam generator(SG) tube in nuclear power plant. Bagging is a method for creating an ensemble of estimator based on bootstrap sampling. For predicting defect size of SG tube, we first generated eddy current testing signals for 4 defect patterns of SG tube with various widths and depths. Then, we constructed single neural network(SNN) and Bagging neural network(BNN) to estimate width and depth of each defect. The estimation performance of SNN and BNN were measured by means of peak error. According to our experiment result, average peak error of SNN and BNN for estimating defect depth were 0.117 and 0.089mm, respectively. Also, in the case of estimating defect width, average peak error of SNN and BNN were 0.494 and 0.306mm, respectively. This shows that the estimation performance of BNN is superior to that of SNN.

Junctional Neural Tube Defect

  • Eibach, Sebastian;Pang, Dachling
    • Journal of Korean Neurosurgical Society
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    • v.63 no.3
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    • pp.327-337
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    • 2020
  • Junctional neurulation represents the most recent adjunct to the well-known sequential embryological processes of primary and secondary neurulation. While its exact molecular processes, occurring at the end of primary and the beginning of secondary neurulation, are still being actively investigated, its pathological counterpart -junctional neural tube defect (JNTD)- had been described in 2017 based on three patients whose well-formed secondary neural tube, the conus, is widely separated from its corresponding primary neural tube and functionally disconnected from corticospinal control from above. Several other cases conforming to this bizarre neural tube arrangement have since appeared in the literature, reinforcing the validity of this entity. The cardinal clinical, neuroimaging, and electrophysiological features of JNTD, and the hypothesis of its embryogenetic mechanism, form part of this review.

Junctional Neurulation : A Junction between Primary and Secondary Neural Tubes

  • Kim, Kyung Hyun;Lee, Ji Yeoun
    • Journal of Korean Neurosurgical Society
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    • v.64 no.3
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    • pp.374-379
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    • 2021
  • Recent case reports of junctional neural tube defect (JNTD) which is a peculiar type of spinal anomaly showing the functional disconnection of the primary and secondary neural tubes has risen interest in the process of junctional neurulation (the connection between the two neural tubes) during development. This article summarizes the clinical features of the JNTD and reviews the literature on the basic research on junctional neurulation.

A Study on the Structure of Neural Network for Predicting Defect Size of Steam Generator Tube in Nuclear Power Plant (원전SG 세관 결함크기 예측을 위한 신경회로망 구조에 관한 연구)

  • Jo, Nam-Hoon
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.24 no.1
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    • pp.63-70
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    • 2010
  • In this paper, we study the structure of neural network for predicting defect size of steam generator tube. After extracting the features from the eddy current testing (ECT) signals, multi-layer neural networks are used to predict the defect size. In order to maximize the prediction performance for the defect size, we should carefully choose the structure of neural networks, especially the number of neurons in the hidden layer. In this paper, it is shown that, for the prediction of defect size, the number of neurons in the hidden layer can be efficiently determined by using cross-validation.

Enhancement of Re-closure Capacity by the Intra-amniotic Injection of Human Embryonic Stem Cells in Surgically Induced Spinal Open Neural Tube Defects in Chick Embryos

  • Lee, Gun-Soup;Lee, Do-Hun;Kim, Eun-Young;Wang, Kyu-Chang;Lee, Won-Don;Park, Sepill;Lim, Jin-Ho
    • Proceedings of the KSAR Conference
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    • 2004.06a
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    • pp.275-275
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    • 2004
  • To evaluate the potential of the stem cell therapy as a method for prenatal management of spinal open neural tube defect (ONTD), the influence of embryonic stem cells injected into the amniotic cavity on the re-closure capacity of spinal ONTD was investgated. Spinal neural tube was incised open for a length of 6 somites using chick embryos of Hamburger and Hamilton stage 18 or 19. (omitted)

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Classification Performance Improvement of Steam Generator Tube Defects in Nuclear Power Plant Using Bagging Method (Bagging 방법을 이용한 원전SG 세관 결함패턴 분류성능 향상기법)

  • Lee, Jun-Po;Jo, Nam-Hoon
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.58 no.12
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    • pp.2532-2537
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    • 2009
  • For defect characterization in steam generator tubes in nuclear power plant, artificial neural network has been extensively used to classify defect types. In this paper, we study the effectiveness of Bagging for improving the performance of neural network for the classification of tube defects. Bagging is a method that combines outputs of many neural networks that were trained separately with different training data set. By varying the number of neurons in the hidden layer, we carry out computer simulations in order to compare the classification performance of bagging neural network and single neural network. From the experiments, we found that the performance of bagging neural network is superior to the average performance of single neural network in most cases.

Improvement of Neural Network Performance for Estimating Defect Size of Steam Generator Tube using Multifold Cross-Validation (다중겹 교차검증 기법을 이용한 증기세관 결함크기 예측을 위한 신경회로망 성능 향상)

  • Kim, Nam-Jin;Jee, Su-Jung;Jo, Nam-Hoon
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.26 no.9
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    • pp.73-79
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    • 2012
  • In this paper, we study on how to determine the number of hidden layer neurons in neural network for predicting defect size of steam generator tube. It was reported in the literature that the number of hidden layer neurons can be efficiently determined with the help of cross-validation. Although the cross-validation provides decent estimation performance in most cases, the performance depends on the selection of validation set and rather poor performance may be led to in some cases. In order to avoid such a problem, we propose to use multifold cross-validation. Through the simulation study, it is shown that the estimation performance of defect width (defect depth, respectively) attains 94% (99.4%, respectively) of the best performance achievable among the considered neuron numbers.

Performance improvement of Classification of Steam Generator Tube Defects in Nuclear Power Plant Using Neural Network (신경회로망을 이용한 원전SG 세관 결함패턴 분류성능 향상기법)

  • Jo, Nam-Hoon;Han, Ki-Won;Song, Sung-Jin;Lee, Hyang-Beom
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.56 no.7
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    • pp.1224-1230
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    • 2007
  • In this paper, we study the classification of defects at steam generator tube in nuclear power plant using eddy current testing (ECT). We consider 4 defect patterns of SG tube: I-In type, I-Out type, V-In type, and V-Out type. Through numerical analysis program based on finite element modeling, 400 ECT signals are generated by varying width and depth of each defect type. In order to improve the classification performance, we propose new feature extraction technique. After extracting new features from the generated ECT signals, multi-layer perceptron is used to classify the defect patterns. Through the computer simulation study, it is shown that the proposed method achieves 100% classification success rate while the previous method yields 91% success rate.

Overview of Secondary Neurulation

  • Catala, Martin
    • Journal of Korean Neurosurgical Society
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    • v.64 no.3
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    • pp.346-358
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    • 2021
  • Secondary neurulation is a morphological process described since the second half of the 19th century; it accounts for the formation of the caudal spinal cord in mammals including humans. A similar process takes place in birds. This form of neurulation is caused by the growth of the tail bud region, the most caudal axial region of the embryo. Experimental work in different animal species leads to questioning dogmas widely disseminated in the medical literature. Thus, it is clearly established that the tail bud is not a mass of undifferentiated pluripotent cells but is made up of a juxtaposition of territories whose fate is different. The lumens of the two tubes generated by the two modes of neurulation are continuous. There seem to be multiple cavities in the human embryo, but discrepancies exist according to the authors. Finally, the tissues that generate the secondary neural tube are initially located in the most superficial layer of the embryo. These cells must undergo internalization to generate the secondary neurectoderm. A defect in internalization could lead to an open neural tube defect that contradicts the dogma that a secondary neurulation defect is closed by definition.