• Journal of Ginseng Research
• /
• v.46 no.2
• /
• pp.255-265
• /
• 2022

Background: Ginsenoside Rb1, a bioactive component isolated from the Panax ginseng, acts as a remedy to prevent myocardial injury. However, it is obscure whether the cardioprotective functions of Rb1 are related to the regulation of endogenous metabolites, and its potential molecular mechanism still needs further clarification, especially from a comprehensive metabolomics profiling perspective. Methods: The mice model of acute myocardial ischemia (AMI) and oxygen glucose deprivation (OGD)-induced cardiomyocytes injury were applied to explore the protective effect and mechanism of Rb1. Meanwhile, the comprehensive metabolomics profiling was conducted by high-performance liquid chromatography and quadrupole time-of-flight mass spectrometry (HPLC-Q/TOF-MS) and a tandem liquid chromatography and mass spectrometry (LC-MS). Results: Rb1 treatment profoundly reduced the infarct size and attenuated myocardial injury. The metabolic network map of 65 differential endogenous metabolites was constructed and provided a new inspiration for the treatment of AMI by Rb1, which was mainly associated with mitophagy. In vivo and in vitro experiments, Rb1 was found to improve mitochondrial morphology, mitochondrial function and promote mitophagy. Interestingly, the mitophagy inhibitor partly attenuated the cardioprotective effect of Rb1. Additionally, Rb1 markedly facilitated the phosphorylation of AMP-activated protein kinase α (AMPKα), and AMPK inhibition partially weakened the role of Rb1 in promoting mitophagy. Conclusions: Ginsenoside Rb1 protects acute myocardial ischemia injury through promoting mitophagy via AMPKα phosphorylation, which might lay the foundation for the further application of Rb1 in cardiovascular diseases.

• Journal of the Society of Disaster Information
• /
• v.17 no.4
• /
• pp.848-863
• /
• 2021

Purpose: On August 16, 2021, the Taliban established the Taliban regime after conquering capital Kabul of the Afghan by using the strong alliance of international terrorist organizations. The Taliban carried out terrorism targeting the Korean people, including the kidnapping of Kim Seon-il in 2004, the abduction of a member of the Saemmul Church in 2007, and the attack on Korean Provincial Reconstruction Team in 2009. Therefore, this research has shown the possibility of Taliban terrorism in Korea. Method: Based on the statistical data on terrorism that occurred in Afghanistan, Taliban's various terrorist activities such as tactics, strategies, and weapons are examined. Consequently, the target facilities and the type of terrorist attacks are analyzed. Result: The Taliban are targeting the Afghan government as their main target of attack, and IS and the Taliban differ in their selection of targets for terrorism. Conclusion: From the result of this research, we recommend Korea need to reinforce the counter terrorism system in soft targets. Because If the Taliban, which has seized control of Afghanistan, and IS, which has established a worldwide terrorism network, cooperate to threaten domestic multi-use facilities with bombing, the Republic of Korea may face a terrorist crisis with insufficient resources and counter-terrorism related countermeasures.

• The Journal of the Korea Contents Association
• /
• v.22 no.4
• /
• pp.222-230
• /
• 2022

Recently, Korea's cultural content industry is developing, and behind the growing recognition around the world is the real-time sharing service of global network users due to the development of science and technology. In particular, in the case of YouTube, its propagation power is fast and powerful in that everyone, not limited users, can become potential video providers. As more than 80% of mobile phone users are using YouTube in Korea, YouTube's information means that psychological factors of users are reflected. For example, information such as the number of video views, likes, and comments of a channel with a specific personality shows a measure of the channel's personality interest. This is highly related to the fact that information such as the frequency of keyword search on portal sites is closely related to the stock market economically and psychologically. Therefore, in this study, YouTube information from a representative entertainment company is collected through a crawling algorithm and analyzed for the causal relationship with major variables related to stock prices. This study is considered meaningful in that it conducted research by combining cultural content, IT, and financial fields in accordance with the era of the fourth industry.

• Journal of Environmental Health Sciences
• /
• v.47 no.6
• /
• pp.521-529
• /
• 2021

Background: The coronavirus disease (COVID-19) has caused changes in human activity, and these changes may possibly increase or decrease exposure to fine dust (PM_2.5). Therefore, it is necessary to evaluate the exposure to PM_2.5 in relation to the outbreak of COVID-19. Objectives: The purpose of this study was to compare and evaluate the exposure to PM_2.5 concentrations by the variation of dynamic populations before and after the outbreak of COVID-19. Methods: This study evaluated exposure to PM_2.5 concentrations by changes in the dynamic population distribution in Guro-gu, Seoul, before and after the outbreak of COVID-19 between Jan and Feb, 2020. Gurogu was divided into 2,204 scale standard grids of 100 m×100 m. Hourly PM_2.5 concentrations were modeled by the inverse distance weight method using 24 sensor-based air monitoring instruments. Hourly dynamic population distribution was evaluated according to gender and age using mobile phone network data and time-activity patterns. Results: Compared to before, the population exposure to PM_2.5 decreased after the outbreak of COVID-19. The concentration of PM_2.5 after the outbreak of COVID-19 decreased by about 41% on average. The variation of dynamic population before and after the outbreak of COVID-19 decreased by about 18% on average. Conclusions: Comparing before and after the outbreak of COVID-19, the population exposures to PM_2.5 decreased by about 40%. This can be explained to suggest that changes in people's activity patterns due to the outbreak of COVID-19 resulted in a decrease in exposure to PM_2.5.

• Journal of Environmental Health Sciences
• /
• v.48 no.2
• /
• pp.66-74
• /
• 2022

Background: The health effects of particulate matter (PM_2.5) bonded with various harmful chemicals differ based on their composition, so investigating and managing their concentrations and composition is vital for long-term management. As industrial complexes emit considerable quantities of pollutants, higher PM_2.5 concentrations and chemical component effects are expected than in other places. Objectives: We investigated the concentration distribution ratios of PM_2.5 chemical components to provide basic data to inform future major emissions control and PM_2.5 reduction measures in industrial complexes. Methods: We monitored five sites near the Ansan and Siheung industrial complexes from August 2020 to July 2021. Samples were collected and analyzed twice per week in spring/winter and once per week in summer/autumn according to the National Institute of Environmental Research in the Ministry of Environments' Air Pollution Monitoring Network Installation and Operation Guidelines. We investigated and compared composition ratios of 29 ions, carbon, and elemental components in PM_2.5. Results: The analysis of PM_2.5 components at the five sites revealed that ion components accounted for the greatest total mass at approximately 50% while carbon components and elemental components contributed 23~28% and 8~10%, respectively. Among the ionic components, NO₃^- occupies the greatest proportion. OC occupies the greatest proportion of the carbon components and sulphur occupies the greatest proportion of elemental components. Conclusions: This study investigated the concentration distribution ratios of PM_2.5 chemical components in industrial complexes. We believe these results provide basic chemical component concentration ratio data for establishing future air management policies and plans for the Ansan and Siheung industrial complexes.

• Journal of Internet of Things and Convergence
• /
• v.8 no.2
• /
• pp.41-48
• /
• 2022

This study tried to empirically explore which issues related to the social service agency for public(as below SSA), that is, social perceptions were formed, by using mess media related to the SSA. This study is meaningful in that it identifies the overall social perception and trend of SSA through public opinion. In order to extract media trend data, the search used the big data analysis system, Textom, to collect data from the representative portals Naver News and Daum News. The collected texts were 1,299 in 2020 and 1,410 in 2021, for a total of 2,709. As a result of the analysis, first, the most derived words in relation to the frequency of text appearance were 'SSA', 'establishment', and 'operation'. Second, as a result of the N-gram analysis, the pairs of words directly related to the SSA 'SSA and public', 'SSA and opening', 'SSA and launch', and 'SSA and Department Director', 'SSA and Staff', 'SSA and Caregiver' etc. Third, in the results of TF-IDF analysis and word network analysis, similar to the word occurrence frequency and N-gram results, 'establishment', 'operation', 'public', 'launch', 'provided', 'opened', ' 'Holding' and 'Care' were derived. Based on the above analysis results, it was suggested to strengthen the emergency care support group, to commercialize it in detail, and to stabilize jobs.

• Economic and Environmental Geology
• /
• v.54 no.6
• /
• pp.615-627
• /
• 2021

The Baekildo fault, a dextral strike-slip fault developed in Baekil Island, Goheung-gun, controls the distribution of tuffaceous sandstone and lapilli tuff and shows a complex fracture system around it. In this study, we examined the spatial variation in the geometry and connectivity of the fracture system by using circular sampling and topological analysis based on a detailed fracture trace map. As a result, both intensity and connectivity of the fracture system are higher in tuffaceous sandstone than in lapilli tuff. Furthermore, the degree of the orientation dispersion, intensity, and average length of fracture sets vary depending on the along-strike variation in structural position in the tuffaceous sandstone. Notably, curved fractures abutting the fault at a high angle occur at a fault bend. Based on the detailed observation and analyses of the fracture system, we conclude as follows: (1) the high intensity of the fracture system in the tuffaceous sandstone is caused by the higher content of brittle minerals such as quartz and feldspar. (2) the connectivity of the fracture system gets higher with the increase in the diversity and average length of the fracture sets. Finally, (3) the fault bend with geometric irregularity is interpreted to concentrate and disturb the local stress leading to the curved fractures abutting the fault at a high angle. This contribution will provide important insight into various geologic and structural factors that control the development of fracture systems around faults.

• KIPS Transactions on Software and Data Engineering
• /
• v.11 no.4
• /
• pp.169-178
• /
• 2022

Morphemes are most primitive units in a language that lose their original meaning when segmented into smaller parts. In Korean, a sentence is a sequence of eojeols (words) separated by spaces. Each eojeol comprises one or more morphemes. Korean morphological analysis (KMA) is to divide eojeols in a given Korean sentence into morpheme units. It also includes assigning appropriate part-of-speech(POS) tags to the resulting morphemes. KMA is one of the most important tasks in Korean natural language processing (NLP). Improving the performance of KMA is closely related to increasing performance of Korean NLP tasks. Recent research on KMA has begun to adopt the approach of machine translation (MT) models. MT is to convert a sequence (sentence) of units of one domain into a sequence (sentence) of units of another domain. Neural machine translation (NMT) stands for the approaches of MT that exploit neural network models. From a perspective of MT, KMA is to transform an input sequence of units belonging to the eojeol domain into a sequence of units in the morpheme domain. In this paper, we propose a deep learning model for KMA. The backbone of our model is based on the BERT-fused model which was shown to achieve high performance on NMT. The BERT-fused model utilizes Transformer, a representative model employed by NMT, and BERT which is a language representation model that has enabled a significant advance in NLP. The experimental results show that our model achieves 98.24 F1-Score.

• The Journal of the Convergence on Culture Technology
• /
• v.8 no.4
• /
• pp.303-311
• /
• 2022

Recently the telemedicine platform firms which have been temporarily permitted since COVID-19 outbreak have increasingly provided online prescription drugs delivery, causing concerns among incumbent providers of medicine, some of whom began to take aggressive actions again them. In this study, using game theoretic market entry - deterrence model, we show that although the incumbent medicine provider can effectively deter entry by the telemedicine platform firms by its preemptive action, accommodation could be a optimal action when telemedicine platform firms already have penetrated the market with their being permitted to do business due to the COVID-19. However, for the incumbent to cooperate for the successful change in the retail market for medicines, policies like placing a ceiling on the maximum number of taking prescriptions by the pharmacists a day in the telemedince platform network, providing favorable exposure of community pharmacists on the telemedicine platform user interface, and allowing community pharmacies to participate as shareholders of the telemedicine platform firms in its initial public opening of capital, are suggested.

• Journal of Intelligence and Information Systems
• /
• v.28 no.2
• /
• pp.263-278
• /
• 2022

With the recent advent of IoT technology, automatic pet feeders are being distributed so that owners can feed their companion animals while they are out. However, due to behaviors of pets, the method of measuring weight, which is important in automatic feeding, can be easily damaged and broken when using the scale. The 3D camera method has disadvantages due to its cost, and the 2D camera method has relatively poor accuracy when compared to 3D camera method. Hence, the purpose of this study is to propose a deep learning approach that can accurately estimate weight while simply using a 2D camera. For this, various convolutional neural networks were used, and among them, the ResNet101-based model showed the best performance: an average absolute error of 3.06 grams and an average absolute ratio error of 3.40%, which could be used commercially in terms of technical and financial viability. The result of this study can be useful for the practitioners to predict the weight of a standardized object such as feed only through an easy 2D image.