• Journal of Haehwa Medicine
• /
• v.2 no.1
• /
• pp.261-274
• /
• 1993

• Journal of Chest Surgery
• /
• v.53 no.4
• /
• pp.205-210
• /
• 2020

Esophageal anastomotic leak is the most common and serious complication following esophagectomy. However, the standard treatment for anastomotic leaks remains unclear. Recently, endoscopic vacuum therapy has become an important non-surgical alternative treatment method for patients with esophageal anastomotic leak. This treatment involves the endoscopic placement of a sponge connected to a nasogastric tube into the defect cavity or lumen. Subsequently, continuous negative pressure is delivered to the cavity through the tube. Several studies have reported a treatment success rate of 80% to 100%. In this study, we review the mechanism of action, the method of performing the procedure, its safety and efficacy, and prognostic factors for failure of endoscopic vacuum therapy in the management of patients with anastomotic leak, and on this basis attempted to confirm the possibility of establishing a standardized treatment protocol using endoscopic vacuum therapy.

• Archives of Plastic Surgery
• /
• v.44 no.1
• /
• pp.76-79
• /
• 2017

Necrotizing fasciitis (NF) is an aggressive soft-tissue infection involving the deep fascia and is characterized by extensive deterioration of the surrounding tissue. Immediate diagnosis and intensive treatment, including debridement and systemic antibiotics, represent the most important factors influencing the survival of NF patients. In this report, we present a case of NF in the abdomen due to an infection caused by a perforated small bowel after abdominal liposuction. It was successfully treated using negative-pressure wound therapy, in which a silicone sheet functioned as a barrier between the sponge and internal organs to protect the small bowel.

• Journal of Trauma and Injury
• /
• v.34 no.1
• /
• pp.75-78
• /
• 2021

A Morel-Lavallée lesion is a post-traumatic closed degloving soft tissue injury after blunt trauma. Infection and skin necrosis frequently occur if it is not treated properly in the early stages. However, there is no clearly established treatment algorithm. In the acute stage, it is mainly treated with aspiration, simple compression, and incisional drainage. In the chronic stage, sclerotherapy is usually performed. If skin necrosis develops, the necrotic tissue is resected and a skin graft is needed. We describe a case of acute Morel-Lavallée lesion in the buttock region that was treated with limited incisional drainage and negative-pressure wound therapy, and also present a review of the literature.

• Journal of Korean Foot and Ankle Society
• /
• v.25 no.4
• /
• pp.190-194
• /
• 2021

A bursa is an obstructive sac filled with synovial fluid and usually occurs in any area of the body exposed to friction. The bursa of the ankle is not a normal anatomical structure and is caused by repetitive trauma, constant friction, or inflammatory disease of the ankle. Bursitis can occur in any bursa in the human body; however it rarely progresses to septic arthritis. We report a rare case of septic ankle arthritis following intractable lateral malleolar bursitis successfully treated with negative-pressure wound therapy.

• The Korean Journal of Nuclear Medicine
• /
• v.35 no.3
• /
• pp.117-124
• /
• 2001

Serum thyroglobulin measurement and I-131 whole-body scintigraphy (WBS) are well-established methods for the detection of recurrence in the follow-up of patients with thyroid carcinoma. However, inconsistent results are observed frequently, and these two methods are not always able to detect recurrence. In some patients, serum thyroglobulin level is elevated but the WBS is negative, because the recurrent tumor is too small and below the sensitivity of the diagnostic scan, or there is a dissociation between thyroglobulin synthesis and the iodine frapping mechanism. In such cases, various nuclear imaging methods including Tl-201 Tc-99m-sestamibi, and F-18-FDG PET can be used besides anatomical imaging methods. Among them, FDG PET localizes recurrent lesions in WBS-negative thyroid carcinoma with high accuracy. Several studies have suggested that empirical high-dose I-131 therapy resulted in a high rate of visualization in post-therapy scans with evidence of subsequent improvement. An important question is when to operate on patients with recurrent tumor. We believe that surgical removal is the best means of treatment for patients with localized persistent tumor, despite the high-dose I-131 therapy. with tumor in thyroid remnant, and with isolated recurrence in the lymph node, lung or bone. In addition, we recommend palliative resection of locally unresectable mass with subsequent treatment with high-dose I-131 therapy. Before I-131 therapy, the evaluation of sodium-iodide symporter expression in thyroid carcinoma can predict iodine uptake. Retinoic acid is known to induce redifferentiation, and to enhance I-131 uptake in thyroid carcinoma. Retinoic acid therapy may represent an alternative approach before high-dose I-131 therapy.

• Journal of Veterinary Clinics
• /
• v.18 no.3
• /
• pp.201-205
• /
• 2001

For evaluating the effect of triple therapy on eradication of gastric Helicobacter species infection in dogs, 7 dogs that had naturally acquired Helicobacter spp. infections were administered amoxicillin, metronidazole and omeparazole orally for 14 days. Changes of infection state were determined by urease test for gastric biopsies and Helicobacter specific PCR analysis for gastric biopsies and fecal samples at 7, 14 days after triple therapy and 30 days after cessation of triple therapy. Although negative results for urease test were obtained 6 of 7 dogs at 14 days after starting triple therapy, PCR analysis for gastric biopsies and fecal samples showed negative results in 3 and 4 dogs respectively. At 30 days after cessation of triple therapy, all tests showed negative results in 3 dogs. Based on these results, diagnostic tests for detercting Helicobacter spp. infection are recommended in dogs having chronic gastritis sign (usually intermittent vomiting) and triple therapy described in this study can be applied for eradicating the organism if the animals were proved to be infected.

• The Journal of Korean Physical Therapy
• /
• v.27 no.6
• /
• pp.386-391
• /
• 2015

Purpose: This study investigated whether the strength imbalance between two muscles can affect the score of EMG based biofeedback game, and whether the EMG based biofeedback game score can be used as predictable indicator of the degree of muscle balance alternating the conventional strength measuring equipment. Methods: 40 participated in this study. Biodex was used to measure the peak torque/weight in order to calculate the muscle strength balance index between plantar flexor and dorsiflexor of ankle joint. And muscle balance index (MBI) was calculated. The EMG biofeedback game scores of dorsiflexor and plantar flexor were acquired, so that the EMG electrodes were attached at tibialis anterior and gastrocnemius. The relationship between the game score and the muscle balance index were analyzed. Results: There was negative correlation between the muscle balance index between plantar flexor and dorsiflexor and the peak torque/weight of plantar flexor (r=-0.70). And there was negative correlation between the muscle balance index between plantar flexor and dorsiflexor and the game score of plantar flexor (r=-0.83). Conclusion: The EMG biofeedback game score had significant relationship with muscle imbalance at ankle joint, so it seems that the game score can be used for predicting the degree of muscle imbalance as a parameter.

• Archives of Plastic Surgery
• /
• v.46 no.5
• /
• pp.470-474
• /
• 2019

Congenital absent sternum is a rare birth defect that requires early intervention for optimal long-term outcomes. Descriptions of the repair of absent sternum are limited to case reports, and no preferred method for management has been described. Herein, we describe the use of porcine acellular dermal matrix to reconstruct the sternum of an infant with sternal infection following attempted repair using synthetic mesh. The patient was a full-term male with trisomy 21, agenesis of corpus callosum, ventricular septal defect, patent ductus arteriosus, right-sided aortic arch, and congenital absence of sternum with no sternal bars. Following removal of the infected synthetic mesh, negative pressure wound therapy with instillation was used to manage the open wound and provide direct antibiotic therapy. When blood C-reactive protein levels declined to ${\leq}2mg/L$, the sternum was reconstructed using porcine acellular dermal matrix. At 21 months postoperative, the patient demonstrated no respiratory issues. Physical examination and computed tomography imaging identified good approximation of the clavicular heads and sternal cleft and forward curvature of the ribs. This case illustrates the benefits of negative pressure wound therapy and acellular dermal matrix for the reconstruction of absent sternum in the context of infected sternal surgical site previously repaired with synthetic mesh.

• Journal of Acupuncture Research
• /
• v.25 no.1
• /
• pp.121-130
• /
• 2008

Objectives : Cupping therapy is a stimulation therapy similar to acupuncture and moxibustion with effects that differ depending on the degree of stimulus. To make the strength of the skin objective in cupping therapy for this study, we measured negative pressure in the cupping jar and calculated the expansion rate of the skin. Subjects and Methods : In this study, we experimented with cupping therapy jars made for sale and used in clinics. We studied the pressure in the jars and the changes on the skin surface by measuring properties. We used commercial jars of four different volumes and diameters and tried to discover the properties on the size of the jar. Results : The results of experiment with the cupping therapy are as follows: 1. The lowest pressure in a jar was measured at $-600{\sim}610mmHg$, and the number of operating of vacuum pump for reaching lowest pressure was increased recording where the volume of the jar would be big, but the lowest pressure was not increased recording where the size of that would be big. 2. As the vacuum pump continued to operate, the pressure gradient in the jar got smaller which shows that the expansion rate of the skin was not linear. The pressure gradient shows different operational numbers on the vacuum pump near 0mmHg/operation unrelated to jar volume. 3. When negative pressure worked on the jar, air in the jar decreased. The percentage of air gradually reduced as the negative pressure acted in the jar. For example, the percentage of skin was 37-66% when the negative pressure, reatched -500mmHg. According to out results, different test areas generate different percentages of air in the jar, presumably related to skin elasticity. This phenomenon was most pronounced with the smallest jars. 4. At -500mmHg, the expansion rate of the skin was 1.57-1.9 on the abdomen, and $1.52{\sim}1.68$ on the back. The expansion rate of the skin appeared greater when the jar was relatively small, and it appeared smaller when the jar volume was relatively large relatively.