• Journal of Yeungnam Medical Science
• /
• 제10권2호
• /
• pp.544-549
• /
• 1993

기질적 정신장애라 함은 뇌세포 기능의 장애로 인한 지남력 장애, 기억력 장애, 인격 기능 및 판단력의 장애와 정서의 천박성으로 특징지어지는 증상군으로 알려져왔다. 이에 본 저자들은 환자가 사회적 고립, 무의욕, 무감동, 사고의 빈약 등의 특징적인 정신분열증 음성증상소견을 주소로 입원하였으나 정밀한 검사를 한 결과 양측 전두엽의 위축으로 인한 기질성 정신장애로 밝혀진 환자를 경험하였기에 그의 임상증상을 문헌고찰과 함께 보고하는 바이다.

• 임상간호연구
• /
• 제14권2호
• /
• pp.103-114
• /
• 2008

Purpose: The purpose of this study was to investigate the level of QoL of the terminal cancer patients at home and to identify any influencing factors on QoL. Method: Subjects of this study consisted of 72 terminal cancer patients who were receiving home care nursing for more than 2 weeks in 6 general hospitals. Data were collected by a self-reporting questionnaire on QoL, pain, physical functioning, and symptom experience from Feb, 2006 to Dec, 2006. Data were analyzed by t-test, one way ANOVA, Pearson correlation coefficients, and multiple regression using SPSS Win 14.0. Results: Mean score of QoL was 98.6(230 in total). Except the level of family coping, general characteristics and disease related variables did not show significant difference in QoL. QoL was higher in the family with better coping, and QoL showed negative correlation with three types of pain, physical functioning, and symptom experiences. Least pain, physical functioning, and level of family coping explained QoL up to 26.7%. Conclusion: The QoL was closely related with pain, physical functioning, symptom experience, and family coping. And the least pain, physical functioning and level of family coping were important factors influencing on QoL of terminal cancer patients. However, some other variables influencing the QoL need to be investigated in the future.

• 대한지역사회영양학회지
• /
• 제8권2호
• /
• pp.138-148
• /
• 2003

Morning sickness during pregnancy is a very common functional problem with different kinds of symptom, but little data are available concerning the nutrition intervention program fur pregnant women in local area. A total of 152 pregnant women who had experienced morning sickness were surveyed to investigate the relationships between morning sickness, nutrient intakes and pregnancy outcome. The results showed that prevalent symptoms were nausea (68.4%), heartburn (59.2%), morning sickness (48.7%), vomiting (42.1%), and constipation (44.7%). The onset of the symptom occurred during the first 3 months (9.3 $\pm$ 2.3 weeks) ; 21.1% of the subjects was experienced two symptom at the same time. This significantly correlated with vomiting (p < 0.01), nausea (p < 0.001), morning sickness (p < 0.001), and heartburn (p < 0.01) with pregnancy weight. There were also correlations between the four symptoms and nutrient intakes. Mean birth weight of 21 newborns was 3.06 $\pm$ 0.42 kg, and the one and five minutes of Apgar scores were 7.74 $\pm$ 0.99 and 8.84 $\pm$ 0.69, respectively. There were negative correlations between vomiting and pregnancy outcomes (p < 0.05). Our data support that morning sickness, especially vomiting during pregnancy is associated with Apgar score and body weight of newborn. (Korean J Community Nutrition 8(2) : 138~148, 2003)

• Asian Pacific Journal of Cancer Prevention
• /
• 제15권1호
• /
• pp.309-314
• /
• 2014

Purpose: Cigarette smoking causes many kinds of cancer, and it is more closely related with lung cancer, rather than other cancers. Smoking is the leading cause of lung cancer and ninety percent of the smokers are male in China, but there is little published data concerning the psychological responses in the male smokers with lung cancer and its influence on the symptom burden. The aim of the study was to verify the hypothesis that male smokers with lung cancer have more positive attitude and less symptom burden, comparing to male non-smokers. Methods: A total of 194 men with cancer in West China Hospital, Sichuan, China, were assessed by self-administered questionnaire. Psychological response was measured by the Chinese version of Mini-Mental Adjustment to Cancer scale (Mini-MAC), and symptom burden was measured by the physical symptom distress scale from the Rotterdam Symptom Checklist (RSCL). Results: We found that smokers with lung cancer got higher scores in positive attitude and a smaller symptom burden than non-smokers. Patients with education lower than high school got higher scores of positive attitude compared to college graduate patients (p=0.038). Smokers with lung cancer who knew the potential carcinogenicity of cigarette showed less negative emotions (p=0.011). The psychological response was not affected by age, clinical stage, cell type, smoking duration and amount. Conclusions: Male smokers with lung cancer have a more positive attitude and fewer symptoms, comparing to male non-smokers. Appropriate psychological intervention for non-smokers with lung cancer deserves more attention.

• 재활간호학회지
• /
• 제7권1호
• /
• pp.78-87
• /
• 2004

Purpose: The purpose of this study was to identify relationship of urinary symptom, urinary discomfort and quality of life among the bladder cancer patients and benign prostate hypertrophy patients, and to contribute health promotion of such patients and nursing intervention development based on this results. Method: Study sample recruited bladder cancer patents(n=49) and benign prostate hypertrophy patients who admitted Seoul National University Hospital from June, 2002 to June, 2003. Both group patients were operated, and prostate hypertrophy patients group (mean 67.8 years old) were older than bladder cancer patients group(60.82 years old). Instruments was composed of general characteristics, urinary symptom scale(19 items), urinary discomfort scale(19 items) and quality of life scale(21 items). Data was analysed SPSS PC + 10. using mean, standard deviation, pearson correlation coefficient. Result as follows: 1. There was a statistically significant difference in occupation between two groups (p=.027). Hypertrophy patients group's age was more older than bladder cancer patients group. 2. The prostate hypertrophy patients group had the significantly higher score in urinary symptom (p=000) and nighttime urination frequency. However, there was no significant difference in incontinence symptoms and the symptoms associated bladder cancer between two groups. 3. The prostate hypertrophy patients group had significantly higher score in urinary discomfort (p=000) than the bladder cancer patients group. However, there was no significant difference incontinence discomfort and the discomfort associated bladder cancer between two groups. 4. The prostate hypertrophy patients group suffered more urinary discomfort than the bladder cancer patients group did. The quality of life the prostate hypertrophy patients group was lower than the quality of life the bladder cancer patients group. Quality of life was no statistically significant difference between two groups (p=000). 5. There was a positive correlation between urinary symptoms and urinary discomfort. However, there was a negative correlation between the quality of life and urination symptoms and discomfort. Conclusions: The prostate hypertrophy patients group had significantly higher score in urinary symptom and urinary discomfort (p=000) than the bladder cancer patients group. The quality of life the prostate hypertrophy patients group was lower than the quality of life the bladder cancer patients group. This means that urinary symptom and urinary discomfort in prostate hypertrophy patient group is more important problem. So, prostate hypertrophy patient group need to control the symptom. Therefore, nurses will be provide the intervention program to improve the bladder function after prostate hypertrophy surgery.

• Journal of Hospice and Palliative Care
• /
• 제20권3호
• /
• pp.188-193
• /
• 2017

목적: 완화적 시기에 말기 암환자의 증상과 가족간병인의 우울 간의 관계에 대한 연구는 매우 드물다. 본 단면연구에서는 말기 암환자의 증상특징과 그들의 가족간병인의 우울 간의 관계에 대해 살펴보고자 하였다. 방법: MD Anderson Symptom Inventory와 Hospital Anxiety and Depression Scale을 이용한 다기관 조사연구가 진행되었다. 총 293쌍의 말기 암환자와 가족간병인이 7개 기관에서 등록되었다. 가족간병인의 우울과 관련된 요인을 추출하고, 보정된 우울점수를 추정하기 위해 다변량 회귀분석이 사용되었다. 결과: 다양한 심리사회적 요인들 중, 가족간병인의 낮은 삶의 질, 낮은 사회적 지지, 배우자 관계, 그리고 더 많은 간병시간 등이 가족간병인의 우울과 유의한 관련성을 보였다. 가족 간병인의 우울여부에 따라, 환자의 몇 가지 증상에서 유의한 차이가 관찰되었다. 관련된 혼란변수를 보정한 이후에도, 음성증상이 없는 환자를 돌보고 있는 가족간병인보다 음성증상을 가진 환자를 돌보고 있는 가족간병인에서 우울점수가 유의하게 낮았다(식욕소실, P=0.005; 졸음, P=0.024; 그리고 입마름, P=0.043). 중증의 식욕소실을 가진 환자를 돌보고 있는 가족간병인의 우울점수는 비중증의 식욕소실을 가진 환자를 돌보고 있는 가족간병인의 우울점수보다 낮았다(P=0.039). 결론: 본 연구결과는 가족간병인의 우울을 평가할 때 환자의 증상 특징이 도움이 될 수 있음을 시사한다.

• 한국산학기술학회논문지
• /
• 제17권11호
• /
• pp.616-628
• /
• 2016

본 연구는 천식환자의 증상경험, 수면의 질 및 삶의 질 간의 관련성을 조사하기 위한 서술적 상관관계 연구이다. 2015년 3월부터 6월까지 서울시 S 상급종합병원 알레르기내과 외래를 방문한 천식환자 146명을 대상으로 하였다. 천식환자의 증상경험은 오의금(1999)이 개발한 도구를, 수면의 질은 Buysse등(1988)에 의해 개발 된 Pittsburgh Sleep Quality Index를, 삶의 질은 Ware등(1992)에 의해 개발된 the Short Form 36-Items Health Survey를 본 연구에 사용하였다. 수집된 자료는 SPSS 20.0 프로그램을 이용하여 각 변수의 빈도, 백분율, 평균과 표준편차, t-test, ANOVA, 사후검증은 Scheffe test, Pearson's correlation coefficient으로 분석하였다. 연구 결과 천식환자의 증상경험은 수면의 질과 양의 상관관계를 나타냈고(r=.468, p<.001), 삶의 질은 신체적 구성요소(r=-495, p<.001)와 정신적 구성요소(r=-.411, p<.001)는 음의 관계를 나타냈다. 이렇듯 대상자의 천식 증상경험, 수면의 질 및 삶의 질은 서로 상관관계 및 통계적 유의한 차이를 나타냈다. 따라서 본 연구를 통해 천식환자의 증상경험을 다차원적인 측면에서 이해하고 천식환자의 수면의 질과 삶의 질을 높이기 위한 간호사정 도구 및 중재 프로그램 개발에 기초적 자료로 활용 될 것이다.

• 생물정신의학
• /
• 제26권1호
• /
• pp.8-13
• /
• 2019

Objectives Disrupted integrities of the fornix and stria terminalis have been suggested in schizophrenia. However, very few studies have focused on the fornix and stria terminalis comparing first-episode schizophrenia (FESZ), chronic schizophrenia (CS), and healthy controls (HCs) with the application of diffusion-tensor imaging (DTI) technique. The objective of this study is to compare the connectivity of the fornix and stria terminalis among FESZ, CS, and HCs. Methods We included the 44 FESZ patients, 39 CS patients and 20 HCs in this study. Voxel-wise statistical analysis of the fractional anisotropy (FA) data was performed using Tract-Based Spatial Statistics to analyze the connectivity of fornix and stria terminalis. In addition, the Scale for the Assessment of Positive Symptoms (SAPS) and the Scale for the Assessment of Negative Symptoms (SANS) were used to evaluate clinical symptom severities. Results There were no significant differences between the FESZ, CS, and HCs in age, sex, education years. The SAPS and SANS scores of the schizophrenia groups showed no significant differences. FA values of the right fornix cres/stria terminalis in the CS group were significantly lower than those in FESZ and HCs. There were no significant differences of FA values of the right fornix cres/stria terminalis between the FESZ and the HCs. Pearson correlation analyses revealed that significant correlation between FA values of the right fornix cres/stria terminalies of the the FESZ group and positive, negative symptom scales, and FA values of the right fornix cres/stria terminalis of the CS group and negative symptom scales. Conclusions This study shows that FA values of the fornix and stria terminalis in the CS were lower than in the FESZ and the HCs. These results suggest that the fornix and stria terminalis can play a role in pathophysiology of schizophrenia. Thus current study can broaden our understanding of the pathophysiology of schizophrenia.

• 동의생리병리학회지
• /
• 제22권6호
• /
• pp.1354-1358
• /
• 2008

In Traditional Korean Medicine it is one of basic principle that personality reflects physical conditions. In both of personality and ordinary symptoms, there are some criteria used for diagnosis whether the patient is in cold or hot condition. We studied the relationship between the criteria of cold-hot shown in personality pattern and ordinary symptom pattern. And also analyzed the relativeness in four constitution type. 877 patients who had visited oriental medical hospital and had been confirmed their constitution by drug response were included in this study. Patients filled out the questionnaire composed of personality and ordinary symptom questions. We selected questions related to cold-hot patterns. Next we made personality cold-hot index(PCHI) and ordinary symptom cold-hot index(OSCHI). The two indices were compared and analyzed totally and from the viewpoint of 4 constitution types. The coefficient of correlation between two indices was not high. In Soemin the coefficient was 0.257, in three other constitution it was lower than 0.200 or negative. In Soemin both indices were lower (cold-biased), but in three other constitution no significant results were found. In Tae-emin OSCHI was higher (hot-biased) than PCHI, in Tae-yangin PCHI was higher than OSCHI significantly. Personality is not affected by cold-hot less than expected. The criteria used for diagnosis of cold-hot seems to be biased on Soemin's.

• 대한간호학회지
• /
• 제33권8호
• /
• pp.1127-1134
• /
• 2003

Background. Although there have been a great number of research studies based on the model of uncertainty in illness, few studies have considered the appraisal portion of model. Purpose. The purpose of this study was to test the mediating effect of appraisal in the model of uncertainty in illness. Additionally, this study aimed to examine the relationships among uncertainty, symptom severity, appraisal, and anxiety in patients newly diagnosed with atrial fibrillation. Methods. This study employed a descriptive correlational and cross-sectional survey design using a face-to-face interview method. Patients diagnosed with atrial fibrillation within the previous 6 months prior to data collection were interviewed by Mishel Uncertainty in Illness Scale-Community Form, appraisal scale, Symptom Checklist-Severity V.3, and State Anxiety Inventory. Results. A total of 81 patients with atrial fibrillation were recruited from two large urban medical centers in Cleveland, Ohio, U.S.A.. Symptom severity was the significant variable in explaining uncertainty ($\beta$=0.34). Individuals with greater symptom severity perceived more uncertainty. Uncertainty was appraised as a danger rather than opportunity, and those with greater uncertainty appraised a greater danger (p<.0l). While the appraisal of opportunity had the negative relationship with anxiety (r=-0.25), the appraisal of danger was positively associated with anxiety (r=0.78). The measure of goodness of fit (Q) of the model was .7863, and the significant test (X$^2$) for the Q was statistically significant (df =3, p<.00l). Accordingly, the overall mediating model of uncertainty in illness was proven not to be fit to the empirical data of patients with atrial fibrillation. Consequently, the mediating effect of appraisal was not supported by the empirical data of this study. Conclusion. The findings of this study were discussed in terms of their relevance compared with those of previous studies or theoretical framework and the plausible explanations on study findings. Lastly, in order to expand the present body of knowledge on uncertainty in illness model, recommendations for the future nursing studies were included.