• 대한관절경학회지
• /
• 제3권1호
• /
• pp.30-34
• /
• 1999

30세의 남자환자로 자가 슬개골 건을 이용한 전방 십자 인대 재건술 후 이식건에 발생한 일과성 석회화 1례를 보고 하고자 한다. 환자는 양측 절개술의 관절경하 전방 십자 인대 재건술을 시행 받았으며 술 후 6개월 방사선 필름 상, 이식 건 주위로 석회화 음영이 나타났으며 술 후 13개월 석회화 음영이 사라졌다. 술 후 2개월 Lachman 검사와 pivot shift 검사에서 음성을 보였으며. KT-1000 Arthrometer 검사 상 20 Ibs에서 건측과 1mm의 차이를 보였으나, 술 후 6개월에 이식 건 주위로 석회화 음영이 나타났을 때는 경도의 전방 불안정성이 관찰되었으며, 이후 석회화 음영이 없어지면서 슬관절의 전방 불안정도 회복되었다.

• 대한간호학회지
• /
• 제50권5호
• /
• pp.658-670
• /
• 2020

Purpose: This study aimed to identify the predictors of blood and body fluid exposure (BBFE) in multifaceted individual (sleep disturbance and fatigue), occupational (occupational stress), and organizational (hospital safety climate) factors, as well as infection prevention behavior. We also aimed to test the mediating effect of infection prevention behavior in relation to multifaceted factors and the frequency of BBFE. Methods: This study was based on a secondary data analysis, using data of 246 nurses from the Shift Work Nurses' Health and Turnover study. Based on the characteristics of zero-inflated and over-dispersed count data of frequencies of BBFE, the data were analyzed to calculate zero-inflated negative binomial regression within a generalized linear model and to test the mediating effect using SPSS 25.0, Stata 14.1, and PROCESS macro. Results: We found that the frequency of BBFE increased in subjects with disturbed sleep (IRR = 1.87, p = .049), and the probability of non-BBFE increased in subjects showing higher infection prevention behavior (IRR = 15.05, p = .006) and a hospital safety climate (IRR = 28.46, p = .018). We also found that infection prevention behavior had mediating effects on the occupational stress-BBFE and hospital safety climate-BBFE relationships. Conclusion: Sleep disturbance is an important risk factor related to frequency of BBFE, whereas preventive factors are infection prevention behavior and hospital safety climate. We suggest individual and systemic efforts to improve sleep, occupational stress, and hospital safety climate to prevent BBFE occurrence.

• 생명과학회지
• /
• 제19권9호
• /
• pp.1289-1293
• /
• 2009

원암단백질로 알려진 Human cervical cancer oncogene (HCCR)은 발암억제 단백질인 p53과 작용하여 다양한 암조직에서 암의 유발을 촉진한다. 그러나, 아직 정확한 발암 유도기전이 알려져 있지 않다. 이러한 의문을 해소하기 위한 일환으로 본 연구에서는 HCCR의 발현이 어떻게 조절되는지를 조사하였다. 이를 위해 먼저 HCCR 5' 쪽의 promoter 영역을 분리하여 Luciferase assay법을 이용하여 K562, HEK293, A549 세포에서 분석하였고, Promoter의 -370에서 -406사이 36bp의 첨가로 promoter활성이 의미 있게 억제됨을 관찰하였다. 또한, 36 bp만을 포함하는 probe를 이용한 mobility shift assays (EMSA)에서 핵단백질이 결합함을 관찰하였고, 컴퓨터를 이용한 분석에서 TG-interacting factor (TGIF)에 대한 consensus sequences 존재함을 관찰하였다. TGIF 만을 포함하는 probe (TC)와 돌연변이를 유발한 probe (mTG)를 이용한 EMSA에서 이 자리에 TGIF가 결합함을 보였다. 또한, TGIF 자리에 돌연변이를 유발하면(pGL3-mTGIF) 발현의 억제가 회복됨을 관찰하였다. 본 연구에서는 HCCR promoter의 특성을 분석하였고, 이 과정에서 -390에서 -366 사이에 TGIF 전사인자가 결합하여 전사활성을 조절함을 증명하였다.

• 지역사회간호학회지
• /
• 제15권2호
• /
• pp.289-297
• /
• 2004

Purpose: This study was conducted to determine factors affecting workers' physiological somatic complain using the Job Stress Model proposed by the National Institute for Occupational Safety and Health (NIOSH). Method: Data were collected from the 1st to the 30th of December 1999. The subjects were 2.123 workers employed at 155 work sites. Collected date were analyzed through SAS/PC program. Result: According to individual characteristics, younger and women groups showed significantly higher physiological somatic complaint than elder men groups. By work condition, groups with higher physiological somatic complaint included workers of irregular shift work. Dark lighting, improper temperature in winter, improper ventilation, inappropriate humidity, unpleasant work environment and crowded work place were significantly related with physiological somatic complaint. By work-related factor, physiological somatic complaint was high in those with higher variance in work load, quantitative work load, role conflict, job burden, role ambiguity and future ambiguity. On the other hand, physiological somatic complaint was low in those with little underutilization of ability. As for the relationships between physiological somatic complaint and non-work related factors, physiological somatic complaint was high in workers who had a side job, were bringing up infants alone, cleaned the house alone, cared for the elderly and disabled persons, were studying, were volunteering at another organization, and were spending 5-10 hours in religious activities per week. Physiological somatic complain was in significantly negative correlations with overall social support, supervisory support and family support, but in significantly positive correlations with co-worker support. Conclusion: The main predictors of physiological somatic complain were gender, shift work pattern, overtime work, ventilation, role ambiguity, role conflict, future ambiguity, job control, variance in work load, overall social support, worker with side job, worker who cleans the house alone, worker who is studying. These predictors explained 19.10% of the total variance of physiological somatic complain.

• Journal of Oral Medicine and Pain
• /
• 제21권2호
• /
• pp.369-382
• /
• 1996

The author performed this study to investige the relationship between condylar movements recorded with Pantronicⓡ and mandibular rotational torque movements with BioEGNⓡ. For this study 56 patients with Temporomandibular disorders(TMD) and 30 dental students without any masticatory signs and symptoms were selected as patients group and control group, respectively. The items recorded with Pantronicⓡ(Denar Corp., USA) were immediate side-shift, progressive side-shift, angle of orbiting path, protrusive path and PRI. BioEGNⓡ(Bioelectric gnathography, Bioresearch Inc., USA) were used to measure the amounts of mandibular rotational torque movements in frontal and horizontal plane, and the distance of mandibular translation at incisal area. Amount of mandibular rotational torque movement depicted between the condyles was automatically analysed by angle and difference in frontal and horizontal plane. The obtained data were processed with SAS program and the conclusion of this study were as follows : 1. Mean values of items between patients group and control group in Pantronic measurements were not significantly different except in left protrusive path and in Pantronic Reproducibility Index(PRI). There were no significant difference of condylar paths by preferred chewing side and affected side between the two groups. 2. The amount of mandibular rotational torque movements were differed in frontal angle and difference on protrusion, and in frontal and in horizontal difference on left excursion between the two groups. But the amounts of translatory movements were actually same on all eccentric movements. 3. The amount of mandibular rotational torque movements with splint mere almost not changed from those without splint, with the exception of in horizontal measurements on protrusion. 4. The correlations of items between in Pantronic measurements and in BioEGN measurements wert not consistently, significant, however, generally the ISS related significantly with horizontal torque movement positively, and with frontal torque movement negatively on the contrary, the PSS showed positive correlation with frontal torque movement, and negative correlation with horizontal torque movement.

• 분석과학
• /
• 제8권2호
• /
• pp.107-116
• /
• 1995

양이온 계면활성제인 cetyltrimethyl ammonium bromide(CTAB)를 첨가함에 따라 4-biphenyl acetate ($BPA^-$) 음이온의 202nm band의 흡광도 변화를 측정하여 CTAB의 CMC를 구하였다. 또한 $30^{\circ}C{\sim}70^{\circ}C$의 온도범위에서 CTAB의 미셀화 과정에 수반되는 열역학적 파라미터를 구하였다. 이 온도범위에서 CTAB의 미셀화 자유에너지는 음의 값을 나타내며 미셀화 엔트로피(${\Delta}S^{\circ}m$)는 큰 양의 값을 나타내고 있다. CTAB의 미셀화 과정은 자발적인 상전이(phase transition) 현상임을 알 수 있었다. $300MHz\;H^1-NMR$ 자료로부터 $BPA^-$ 음이온의 CTAB 미셀내의 배향을 알 수 있었다. $BPA^-$ 음이온의 방향족 기가 CTAB 미셀내의 palisade layer까지 침투하여 혼합 미셀을 형성함을 알 수 있었다.

• 대한화학회지
• /
• 제35권4호
• /
• pp.335-342
• /
• 1991

헥사메틸벤젠과 1,3,5-트리니트로벤젠, 테트라클로로 파라벤조퀴논 및 테트라시아노 에틸렌간에 형성되는 전하이동착물의 안정도에 미치는 압력과 온도의 영향을 사염화탄소 용액내에서 분광광도법으로 연구하였다. 압력 및 온도증가에 따른 각계 착물들의 평형상수를 구하고 이 값으로부터 착물형성에 대한 열역학적 파라미터를 산출한 결과 헥사메틸벤젠과 각계의 전하이동착물의 상대적 안정도가 1,3,5-트리니트로벤젠 < 테트라클로로 파라벤조퀴논 < 테트라시아노 에틸렌 순으로 나타났다. 이러한 사실은 헥사메틸벤젠에 대한 그들의 상대적 산성도를 의미하며, 이 현상은 전자받게들의 음유도 효과와 입체장애 효과로 설명할 수 있다. 또 각 착물들의 압력 증가에 의한 적색이동, 온도 증가에 의한 청색이동 현상 및 압력 변화에 의한 진동자세기의 관계를 열역학 함수와 관계지워 설명하였다.

• Investigative Magnetic Resonance Imaging
• /
• 제23권4호
• /
• pp.341-350
• /
• 2019

Purpose: To determine the MR parameters affecting India ink artifacts on opposed-phase chemical shift magnetic resonance (MR) imaging. Materials and Methods: The use of a female Sprague-Dawley rat was approved by our Institutional Animal Care and Use Committee. Using an iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL) images, which is a modified Dixon method, axial opposed-phase images of the abdominal cavity were obtained with different MR parameters: series 1, different repetition times (TRs; 400, 2000, and 4000 ms); series 2, different echo times (TEs; 10, 50, and 100 ms); series 3, different field of views (FOVs; 6, 8, 16, and 24 cm); series 4, different echo train lengths (ETLs; 2, 4, and 8); series 5, different bandwidths (25, 50, and 85); and series 6, different slice thicknesses (1, 2, 4, 8, and 16 mm). Artifacts on opposed images obtained with different parameters were compared subjectively by two radiologists. For objective analysis, the thickness of the artifact was measured. Spearman's correlation between altered MR parameters and thicknesses of India ink artifact was obtained via objective analysis. Results: India ink artifact was increasingly apparent using shorter TE, larger FOV and ETL, and thicker slices upon subjective analysis. The objective analysis revealed a strong negative correlation between the thickness of the artifact and TE (r = -0.870, P < 0.01); however, strong positive correlations were found between FOV (r = 0.854, P < 0.01) and slice thickness (r = 0.971, P < 0.01). Conclusion: India ink artifact was thicker with shorter TE, larger FOV, and larger slice thickness.

• 한국진공학회지
• /
• 제9권3호
• /
• pp.249-253
• /
• 2000

차세대 마이크로파 유전체 소자에 응용하기 위한 $MgTiO_3$ 박막을 펄스 레이저 증착법(PLD, pulsed laser deposition)을 이용하여 400-$500^{\circ}C$에서 비정질 상태로 실리콘 기판 위에 성장시킨 후 전기적 특성을 분석하였다. PLD로 증착된 $MgTiO_3$ 박막의 전기적 특성은 성장시 온도에 의존하였다. 즉, 증착 온도가 낮아짐에 따라 $MgTiO_3$ 박막 내부에 존재하는 이상정전하 결함 밀도가 증가하였으며, 이들 결함과 실리콘 기판과의 전하교환에 의하여 High Frequency(HF) C-V 곡선이 음의 방향으로 이동하는 현상이 관측된 것으로 사료된다. 또한, 증착 온도간 HF C-V 곡선 이동 폭 및 이상정전하 밀도는 ~l00$\AA$ 두께의 $SiO_2$ 중간층을 사용할 경우에 현저히 감소함을 확인하였다.

• 전기전자학회논문지
• /
• 제25권3호
• /
• pp.511-516
• /
• 2021

AlGaN/GaN 반도체 위에 금속이 접합된 HEMT와 SiO₂와 NiO를 게이트 층간막으로 갖는 MOSHFET를 제작하고 NiO 박막에 따른 효과와 특성변화의 원인을 연구하였다. HEMT 구조에서 보인 -3.79 V의 문턱전압은 SiO₂를 층간막으로 했을 때 - 5.52 V로 -1.73 V의 음방향 변화를, NiO를 층간막으로 했을 때 -2.76 V로 +1.03 V의 양방향 변화를 나타냈다. 또 NiO MOSFET의 경우 선형성이 증가하여 넓은 범위에 걸쳐 균일한 트랜스컨덕턴스 특성을 나타냈으며 0 V 이상의 게이트 전압에서는 HEMT와 SiO₂ MOSHFET보다 더 높은 값을 보였다. 게이트에 입력된 펄스신호가 -5 V~0 V로 스윙할 때 HEMT의 포화 드레인 전류는 0.1 Hz~10 Hz의 주파수에서 20%의 감소를 보인 뒤 그 값을 유지하였으나, NiO MOSHFET은 10 Hz에서부터 지속적으로 감소하여 서로 다른 응답특성을 보였다.