• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.193.3-194
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• 2003

Platelets play critical roles in both hemostasis and thrombosis. It was reported that platelet aggregation is associated with an increase in superoxide production and can be inhibited by hydroxyl radical scavengers. In the course of our search for the anti-platelet, anti-coagulant and/or anti-oxidative components from plants, the MeOH extract of Crassula cv. "Himaturi" (Crassulaceae) was observed to have both anti-aggregatory and anti-coagulant effects. A novel compound, 12-O-(4'-O-methyl-galloyl)-bergenin (1), was isolated as an active component from the EtOAC soluble fraction. (omitted)

• 한국환경복원기술학회지
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• 제7권2호
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• pp.75-86
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• 2004

This study aims to figure out ecological characteristic of natural forests focusing on vegetation as a way of ecological renovation for the restoration of naturalness for golf courses that were constructed in the Country and to present vegetation models and appropriate tree species for the purpose. The study site is P golf club, which is located in Gapyong-gun, Kyeonggi Province. The site is within a forest where the grade from the natural ecology map is the first one and the level from the green index accounts for the eight, thus showing a typical environment for a golf course in terms of location. The location of the site explains a reason for restoration. The major substance of the study is to conduct ecological evaluation of vegetation structures around and inside the golf course and to present a vegetation model. In order to evaluate the ecological characteristics of the vegetation structures, the analysis of the study covered succession stages, multi-layer vegetation structures and species diversity. Plant communities that have high species diversity were selected for the vegetation model and proper density and species were proposed considering the number of species and individuals and distances between trees. The vegetation restoration model targets succession into an oak forest. Within a unit of 100 $m^2$, the recommended model include a tall-tree layer with 11 trees such as Quercus serrata and Quercus mongolica, a sub-tall-tree layer with 12 trees including Quercus mongolica, Quercus serrata, Prunus sargentii, Fraxinus rhynchophylla and Acer pseudo sieboldianum, a shrub layer with 32 trees from 16 species, and a grass layer with a cover rate of 45 %. The proposed vegetation restoration model needs to apply to : 1) damaged natural forests by the construction of golf courses; 2) boundaries between golf courses and surrounding forests; 3) buffer zones; 4) open spaces in between courses; and 5) areas between greens and tees where open spaces are available in a mass. In conclusion, one of the most important factors in presenting a vegetation model for the restoration of naturalness in the golf course and other damaged forests is to provide multi-layer vegetation structures that are composed of native species. As for the specific application for the site, it is recommended to manage the vegetation in such a way that the environment of the site can have a similar environment to the surrounding forest which is expected to succeed into an oaks-dominant one.

• Childhood Kidney Diseases
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• 제26권1호
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• pp.1-10
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• 2022

Congenital isolated hydronephrosis encompasses a spectrum of physiologic states that spontaneously resolve and pathologic obstruction that necessitates surgical intervention. Distinguishing patients whose condition will resolve, those who will require stringent follow-up, and those who will eventually need surgical intervention present a challenge to clinicians, particularly because no unified guidelines for assessment and follow-up have been established. The recognition of the natural course and prognosis of hydronephrosis and a comprehensive understanding of the currently proposed consensus guidelines may aid in multidisciplinary treatment and in providing proper counseling to caregivers. In this review, we aimed to summarize the literature on the grading systems and management strategies for congenital isolated hydronephrosis.

• Archives of Pharmacal Research
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• 제20권6호
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• pp.633-636
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• 1997

In the course of searching for PAF receptor antagonists, pregomisin (1) and chamigrenal (2) were isolated from the fruits of Schizandra chinensis Baill by the bioactivity-guided isolation. Both compounds showed PAF antagonistic activity and the $IC_{50}$ values were $4.8{\times}10^{-5} M and 1.2{\times}10^{-4}M,$ respectively. In addition, the $^{13}C$ NMR assignments of 1 and 2 using DEPT, HMQC, COLOC and HMBC were reported for the first time.

• 한국환경복원기술학회지
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• 제11권4호
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• pp.75-90
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• 2008

The golf course has many problems that are a pollution of river, a extinction of habitat by destructing a forest and a simplication of species composition. Therefore, this study was carried out to examine the ecological characteristics of vascular plants in construct-reserved site of golf course. The results were as follow. The vascular plants were summarized as 342 taxa; 86 families, 231 genera, 295 species, 42 varieties and 5 forma. In the results by the location environments of vegetation, Salix caprea community and wetland species like Persicaria thunbergii were appeared in the swamp. Especially, S. caprea will be made use of promoting a landscape. In the stream, Stephanandra incisa community has a functions like an ecological axis and a corridor of wild animals. The planting technique will be applied to using Atractylodes japonica and Ainsliaea acerifolia in the lower part of Pinus densiflora and Quercus mongolica. Because Rhododendron schlippenbachii and Convallaria keiskei grew by layer in Q. variabilis community, this will be made use of natural vegetation model. The rare plants were 2 taxa; Aristolochia contorta and Iris ensata var. spontanea. To preserve their community, we will prohibit a development and remove a threatening factor. The endemic plants were 4 taxa; Salix caprea, Clematis trichotma, Spiraea prunifolia for. simpliciflora and Weigela subsessilis. The naturalized plants were 19 taxa; Rumex crispus, Bildedykia dumetora and so on. To establish the quantitative management plan, we will obtain a ecological information about a naturalized plants in accumulating by season, community and land use pattern.

• 자원리싸이클링
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• 제14권4호
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• pp.10-16
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• 2005

고속도로 건설 및 유지관리 과정에서 발생되는 폐콘크리트의 현장파쇄 및 재활용을 위하여 파쇄시스템 선정, 순환골재 생산, 도로용 재료의 시방기준 준수여부를 평가하였다. 그 결과 순환골재에 부착된 모르터의 영향으로 천연쇄석에 비하여 낮은 물성값을 나타내었으며, 입도시험결과 임팩트 크러셔 또는 죠, 큰크러셔 조합형은 소요입도에 적합한 순환골재를 생산할 수 있었다. 동상방지층에 적용할 경우 함수비 변동에 의한 건조밀도 변화가 작으므로 천연골재에 비하여 관리가 쉬운 장점이 있으나, 빈배합콘크리트 기층은 시멘트에 의한 미분량 증가로 흡수율의 영향이 감소하였다. 또한 재령 7일 압축강도는 순환골재의 종류에 관계없이 10MPa를 상회하므로 현장적용에는 큰 문제가 없음을 알 수 있었다.

• 디지털융복합연구
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• 제14권4호
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• pp.387-396
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• 2016

본 논문에서는 기존 연구논문과 달리 성별의 차이, 계열별 학문특성의 차이, 전형유형별 차이 등이 학업성취도에 미치는 영향을 분석하였다. 남자는 인문사회계열에서 학생부위주전형이 우수하고, 자연계열에서는 수능위주전형이 우수했다. 여자는 인문사회계는 수능과 학생부를 모두 사용하는 전형이 우수하지만 큰 차이는 없었다. 그러나, 자연계열은 수능위주전형이 우수한 것으로 나타났다. 예체능계는 뚜렷한 특징을 보이고 있지 않지만, 수능위주전형이 우수한 것으로 나타났다. 인문사회계는 남자와 여자 모두 학업성취도에서 큰 차이를 보이고 있지 않으므로 입학사정관제가 정착되고 성과를 내고 있는 것으로 나타났다. 하지만 자연계는 남자와 여자 모두 학업성취도가 수능위주전형보다 낮게 나타나고 있다. 이는 자연계열에서 중요한 과목이 수학과 과학이므로 나타나는 현상이다. 이를 해결하기 위해서는 자연계열의 입학사정관제는 수학 및 과학의 기초학업능력을 반영하여 선발되어야 하고, 또한 입학 후 수학 및 과학의 기초학업능력을 향상시킬 수 있는 추수지도 방안이 반드시 필요한 것으로 보인다.

• Molecules and Cells
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• 제39권6호
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• pp.468-476
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• 2016

PLZF-expressing invariant natural killer T cells and CD4 T cells are unique subsets of innate T cells. Both are selected via thymocyte-thymocyte interaction, and they contribute to the generation of activated/memory-like CD4 and CD8 T cells in the thymus via the production of IL-4. Here, we investigated whether $PLZF^+$ innate T cells also affect the development and function of $Foxp3^+$ regulatory CD4 T cells. Flow cytometry analysis of the thymus and spleen from both CIITA transgenic C57BL/6 and wild-type BALB/c mice, which have abundant $PLZF^+$ CD4 T cells and invariant natural killer T cells, respectively, revealed that $Foxp3^+$ T cells in these mice exhibited a $CD103^+$ activated/memorylike phenotype. The frequency of $CD103^+$ regulatory T cells was considerably decreased in $PLZF^+$ cell-deficient $CIITA^{Tg}Plzf^{lu/lu}$ and $BALB/c.CD1d^{-/-}$ mice as well as in an IL-4-deficient background, such as in $CIITA^{Tg}IL-4^{-/-}$ and $BALB/c.IL-4^{-/-}$ mice, indicating that the acquisition of an activated/ memory-like phenotype was dependent on $PLZF^+$ innate T cells and IL-4. Using fetal thymic organ culture, we further demonstrated that IL-4 in concert with TGF-${\beta}$ enhanced the acquisition of the activated/memory-like phenotype of regulatory T cells. In functional aspects, the activated/ memory-like phenotype of Treg cells was directly related to their suppressive function; regulatory T cells of $CIITA^{Tg}PIV^{-/-}$ mice more efficiently suppressed ovalbumin-induced allergic airway inflammation compared with their counterparts from wild-type mice. All of these findings suggest that $PLZF^+$ innate T cells also augmented the generation of activated/memory-like regulation via IL-4 production.

• 한국환경복원기술학회지
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• 제18권3호
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• pp.23-38
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• 2015

The study was initiated with Kentucky bluegrass (KB, Poa pratensis L.) to investigate germination and early establishment characteristics of new cultivars for a practical application to turfgrass establishment such as parks, athletic field and golf course etc. Fifteen cultivars were evaluated in different experiments. An alternative condition for a KB germination test required by International Seed Testing Association (ISTA) was applied in Experiment I, consisting of 8-hr light at $25^{\circ}C$ and 16-hr dark at $15^{\circ}C$ (ISTA conditions). Experiment II was conducted under a room temperature condition of 5 to $25^{\circ}C$ (natural conditions). Seed germinating vigor, germination speed and germination peak time were measured in both experiments. Significant differences were observed in seed germinating vigor, germination speed and germination peak time. Seed germinating vigor was variable with different environments and cultivars. It was 75.25 to 89.50% under ISTA conditions and 75.75 to 90.25% under natural conditions. There were considerable variations in early germination characteristics among KB cultivars according to different environments. Early germination characteristics showed that all cultivars were 3 to 5 days faster in germination under ISTA conditions, when compared with natural conditions. The germination speed, measured as days to seed germination of 50% to 80%, was much faster with 'Midnight II', 'Excursion' and 'Midnight' under ISTA conditions. But it was faster with 'Midnight II', 'Excursion' and 'Odyssey' under natural conditions. Differences was also observed in germination peak time with cultivars and growing conditions. It ranged 5.94 to 14.88 days under ISTA conditions and 4.71 to 13.06 days under natural conditions. Regardless of the environment conditions, the shortest cultivars were 'Odyssey' and 'Midnight II'. The longest ones were 'Nuglade' under ISTA condition and 'Moonlight' under natural conditions. Considering germinating vigor, germination speed and germination peak time, 'Midnight II', 'Excursion', 'Midnight', and 'Odyssey' were regarded as excellent cultivars under ISTA conditions in terms of early establishment characteristics, while 'Midnight II', 'Excursion', 'Odyssey', and 'Courtyard' under natural conditions. These results suggest that an intensive germination test be needed prior to planting, for investigating the early germinating vigor, germination speed and germination peak time. Also, a proper cultivar selection and comprehensive site analysis for the growing environmental conditions should be done before turfgrass establishment such as golf course construction.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제23권5호
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• pp.435-446
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• 2001

Natural Killer/T-cell(NK/TC) lymphoma is a rare disease of oral and maxillofacial region with an aggressive clinical course, showed unusual clinical manifestations. Prognosis is generally poor and the disease is invariably fatal after systemic dissemination. A case of nasal NK/TC non-Hodgkin's lymphoma in the left maxilla that showed unusual clinical manifestations and a fulminant course of disease, are described with literature reviews. A 81-year-old female patient presented with rapidly growing ulceration and general malaise after extraction of right upper second premolar NK/TC lymphoma was subsequently detected by biopsy. rapid and wide invasion from maxilla to mandible developed within 10 days and multiple metastasis to whole body was after a few weeks. Although the time relationship is not clear, local invasion and multiple metastasis could be dissemination from localized disease of NK/TC. As seen in my case, the course can be excessively aggressive and fulminant even though it first appeared as a localized ulceractive lesion. She is expired 2 months after biopsy. Positivity of immunohistochemical stain (CD56, LCA, UCHL-1, CD3), which is a specific characteristic of NK/TC, may serve as a factor showing a poor prognosis of a malignant lymphoma