• Title/Summary/Keyword: Natural

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A Comparison on the Management Assessment of Professionals and Users for the City Natural Park - Focused on the City Natural Park in Incheon Metropolitan City - (전문가·이용자간 평가비교를 통한 도시자연공원 관리방안 - 인천광역시 도시자연공원을 중심으로 -)

  • Oh, Dong-Jun;Lee, Jae-Keun
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.8 no.3
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    • pp.21-32
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    • 2005
  • In Incheon metropolitan city, the urban open space areas are deficient and it is nearly impossible to obtain newly the land for parks by reason of the risk of the land value, the budgetary deficit and so forth. Therefore, it seems to be urgent to consider how to manage the established urban natural park efficiently to enhance the quality of recreational experiences of the public. The organization for the urban natural parks management is to be completely put in good order, for the objects to manage is changeable as well as diverse and what users need should be full satisfied. The purpose of this study is to investigate the differences of urban natural park's management suggest the improvement and development directions in urban natural park by group(professionals and Users). To do this, data were collected in the typical regions by urban natural park for this study, using the questionnaires. In these urban natural park, the on-site survey was carried out the users of these urban natural park during October in 2004. Also The analysis was done with the valid questionnaires of user's 644 and professional's 146. The questionnaires contained three of categories : openspace types' satisfaction and urban natural park's satisfaction, and management, and park user's socioeconomic characteristics and behaviors. Data collected from respondents were analysized by descriptive statistics, T-test, factor analysis and regression analysis. The results of this study can be summarized as follows; The evaluation of urban natural park management is predicted the operation management. So, one can draw a conclusion that user's needs is likely to be increased correspondingly as urban natural park planning and design, management which meets the overall satisfaction. Using the results of this study, we can make a guideline for a park management program, market positioning, standards and provisions of urban natural park by group.

Chemical Genomics with Natural Products

  • Jung, Hye-Jin;Ho, Jeong-Kwon
    • Journal of Microbiology and Biotechnology
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    • v.16 no.5
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    • pp.651-660
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    • 2006
  • Natural products are a rich source of biologically active small molecules and a fertile area for lead discovery of new drugs [10, 52]. For instance, 5% of the 1,031 new chemical entities approved as drugs by the US Food and Drug Administration (FDA) were natural products between 1981 and 2002, and another 23% were natural product-derived molecules [53]. These molecules have evolved through millions of years of natural selection to interact with biomolecules in the cells or organisms and offer unrivaled chemical and structural diversity [14, 37]. Nonetheless, a large percentage of nature remains unexplored, in particular, in the marine and microbial environments. Therefore, natural products are still major valuable sources of innovative therapeutic agents for human diseases. However, even when a natural product is found to exhibit biological activity, the cellular target and mode of action of the compound are mostly mysterious. This is also true of many natural products that are currently under clinical trials or have already been approved as clinical drugs [11]. The lack of information on a definitive cellular target for a biologically active natural product prevents the rational design and development of more potent therapeutics. Therefore, there is a great need for new techniques to expedite the rapid identification and validation of cellular targets for biologically active natural products. Chemical genomics is a new integrated research engine toward functional studies of genome and drug discovery [40, 69]. The identification and validation of cellular receptors of biologically active small molecules is one of the key goals of the discipline. This eventually facilitates subsequent rational drug design, and provides valuable information on the receptors in cellular processes. Indeed, several biologically crucial proteins have already been identified as targets for natural products using chemical genomics approach (Table 1). Herein, the representative case studies of chemical genomics using natural products derived from microbes, marine sources, and plants will be introduced.

Study of Simultaneous Analysis of Indicator Components of DTP(Digital Textile Printing) Textile Products Using HPLC-MS/MS - Focusing on Natural Dyes - (HPLC-MS/MS를 활용한 DTP(Digital Textile Printing) 제품의 지표성분 동시분석법 연구 - 천연염료를 중심으로 -)

  • Lee, Wonkyoung;Sung, Eunji;Moon, Joung Ryul;Kim, Miji;Kim, Jonghoon
    • Fashion & Textile Research Journal
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    • v.23 no.6
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    • pp.844-851
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    • 2021
  • Due to the increase in consumers' interest about well-being, interest in eco-friendly products has been increasing due to the harmful effects of various harmful substances contained in textile products and environmental issues. As a result, natural dyes of less potential risk than synthetic dyes and digital textile printing(DTP) textile products with less environmental pollution are drawing attention. However, due to the lack of evaluation criteria for DTP textile products with natural ink and the nature of many colors are stacked layer by layer for dying, the need for simultaneous analysis is emerging. To evaluate whether the natural dye is derived from natural ingredients, the biocarbon content is analyzed. However, in the case of ink made using natural dyes and DTP textile products using natural ink, it is difficult to analyze the biocarbon content due to the limitation of the presence of a small amount of dye contained therein. In this study, we were shown the possibility of natural derived verification by cross-checking the analytes of natural dyes (Persicaria tinctoria, an indigo dye; Dactylopius coccus, a light red; and Curcum longa L., i.e., turmeric) and natural ink with HPLC-MS/MS. The coefficient of determination was 0.999 or higher, the limit of quantification was 0.647-3.664 ㎍/L and a %RSD of each indicator material was less than 10. Then, the extraction amount of natural dyes for five patterned fabrics was analyzed.

Antioxidative and Antifungal Activity of Equisetum arvense L. (쐐뜨기의 항진균 및 항산화 효과)

  • Chun Hyun Ja;Kim Young Hyun;Lee Hong;Lee Young Hang;Chai Kyu Yun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.5
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    • pp.1490-1493
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    • 2004
  • We investigated antifungal and antioxidant activity of Equsetum arvense L. The sterile stems of Equsetum arvense L. were extracted with methanol and then fractionated with n-hexane, ethyl acetate, butanol, and water. And their antifungal activities were determined by using paper disk diffusion method and (1. 3)β-glucan synthase inhibitory activity assay, and antioxidant activities were determined by using DPPH method. The ethyl acetate fraction showed antifungal activity on Candidas albacans in both disk diffusion and enzyme assays. This also showed antioxidant activity in DPPH assay. Further fractionation with ethyl acetate fraction was performed to obtain effective fractions. 4, 5, 6 and 7 fractions showed the significant antifungal antivities, and, 4 and 5 fractions showed the strongest antioxidative activity.