• Journal of the Institute of Electronics Engineers of Korea CI
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• v.45 no.4
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• pp.12-18
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• 2008

Researches on particle physics have benefited our everyday life in many aspects. They have tested the safety of the objects we use everyday, conducted experiments to examine harmful environments to man, and treated diseases. Despite the usefulness of particle physics in a range of fields, however, it's difficult to conduct researches and experiments directly. But the advancements in the computer industry have allowed for experiments of particle physics in virtual simulations. One of the foremost simulation libraries for particle physics that have been researched actively these days, Geant4 has been put to diverse uses in particle physics. This study designed GUI so that physicists, who were not good at programming, could use a simulation library faster, more accurately, and more conveniently. It also developed the Geant4Editor, a simulation automation framework. The advantages of the Geant4Editor include automatic generations of essential classes in a simulation using Geant4 libraries and real-time reflection of user demands in a simulation. It also allows for efficient management of resources(user-created data) through the Data Manager.

• Journal of Korea Water Resources Association
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• v.47 no.3
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• pp.257-267
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• 2014

The impact of the combination of changes in temperature and rainfall due to climate change on surface water resources is important in hydro-meteorological research. In this study, 4 hydro-meteorological (HM) models from the Rainfall Runoff Library in the Catchment Modeling Toolkit were used to model the impact of climate change on runoff in streams for 5 river basins in the Republic of Korea. Future projections from 2021 to 2040 (2030s), 2051 to 2070 (2060s) and 2081 to 2099 (2090s), were derived from 12 General Circulation Models (GCMs) and 3 representative concentration pathways (RCPs). GCM outputs were statistically adjusted and downscaled using Long-Ashton Research Station Weather Generator (LARS-WG) and the HM models were well calibrated and verified for the period from 1999 to 2009. The study showed that there is substantial spatial, temporal and HM uncertainty in the future runoff shown by the interquartile range, range and coefficient of variation. In summary, the aggregated runoff will increase in the future by 10~24%, 7~30% and 11~30% of the respective baseline runoff for the RCP2.6, RCP4.5 and RCP8.5, respectively. This study presents a method to model future stream-flow taking into account the HM model and climate based uncertainty.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.44 no.1
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• pp.51-58
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• 2007

This paper presented an adaptive pipeline architecture for a high-performance and low-power asynchronous processor. The proposed pipeline architecture employed a stage-skipping and a stage-combining scheme. The stage-skipping scheme can skip the operation of a bubble stage that is not used pipeline stage in an instruction execution. In the stage-combining scheme, two consecutive stages can be joined to form one stage if the latter stage is empty. The proposed pipeline architecture could reduce the processing time and power consumption. The proposed architecture supports multi-processing in the EX stage that executes parallel 4 instructions. We designed an asynchronous microprocessor to estimate the efficiency of the proposed pipeline architecture that was synthesized to a gate level design using a $0.35-{\mu}m$ CMOS standard cell library. We evaluated the performance of the target processor using SPEC2000 benchmark programs. The proposed architecture showed about 2.3 times higher speed than the asynchronous counterpart, AMULET3i. As a result, the proposed pipeline schemes and architecture can be used for asynchronous high-speed processor design

• Journal of the Korean Society for information Management
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• v.37 no.3
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• pp.301-326
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• 2020

This study analyzed recent cases of transition to open access(OA) journals in humanities and social sciences(HSS) in foreign countries to find a way to transition to OA journals in Korea. Ling OA and UP led by researchers, OLH and KU led by libraries, S2O led by publishers and L+F model led by funders and libraries were analyzed. Programs by national funding agencies such as the Norwegian Research Council, Canada Social Sciences and Humanities Research Council, Austrian Science Fund, and Swiss Academy of Humanities and Social Sciences were also reviewed. Based on the results of the analyses, this study suggests for transition in Korean HSS field as follows; 1) transitions to open access journals in HSS should be supported at national level 2) the stakeholder in scholarly communications such as the nation, universities, libraries, research funders, scholarly societies etc has their own role in the transition but funders and libraries are the most important in financial support for open access publishing 3) but the financial support for the first stage of the transition should be done at national level 4) and open access journal publishing consortium comprised of libraries and information service institutions in the public sector such as KERIS, KISTI and the national library should be established 5) non commercial publishing platforms for scholarly societies should be developed and distributed.

• Journal of Intelligence and Information Systems
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• v.18 no.3
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• pp.53-77
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• 2012

This study analyses the difference of contents and tones of arguments among three Korean major newspapers, the Kyunghyang Shinmoon, the HanKyoreh, and the Dong-A Ilbo. It is commonly accepted that newspapers in Korea explicitly deliver their own tone of arguments when they talk about some sensitive issues and topics. It could be controversial if readers of newspapers read the news without being aware of the type of tones of arguments because the contents and the tones of arguments can affect readers easily. Thus it is very desirable to have a new tool that can inform the readers of what tone of argument a newspaper has. This study presents the results of clustering and classification techniques as part of text mining analysis. We focus on six main subjects such as Culture, Politics, International, Editorial-opinion, Eco-business and National issues in newspapers, and attempt to identify differences and similarities among the newspapers. The basic unit of text mining analysis is a paragraph of news articles. This study uses a keyword-network analysis tool and visualizes relationships among keywords to make it easier to see the differences. Newspaper articles were gathered from KINDS, the Korean integrated news database system. KINDS preserves news articles of the Kyunghyang Shinmun, the HanKyoreh and the Dong-A Ilbo and these are open to the public. This study used these three Korean major newspapers from KINDS. About 3,030 articles from 2008 to 2012 were used. International, national issues and politics sections were gathered with some specific issues. The International section was collected with the keyword of 'Nuclear weapon of North Korea.' The National issues section was collected with the keyword of '4-major-river.' The Politics section was collected with the keyword of 'Tonghap-Jinbo Dang.' All of the articles from April 2012 to May 2012 of Eco-business, Culture and Editorial-opinion sections were also collected. All of the collected data were handled and edited into paragraphs. We got rid of stop-words using the Lucene Korean Module. We calculated keyword co-occurrence counts from the paired co-occurrence list of keywords in a paragraph. We made a co-occurrence matrix from the list. Once the co-occurrence matrix was built, we used the Cosine coefficient matrix as input for PFNet(Pathfinder Network). In order to analyze these three newspapers and find out the significant keywords in each paper, we analyzed the list of 10 highest frequency keywords and keyword-networks of 20 highest ranking frequency keywords to closely examine the relationships and show the detailed network map among keywords. We used NodeXL software to visualize the PFNet. After drawing all the networks, we compared the results with the classification results. Classification was firstly handled to identify how the tone of argument of a newspaper is different from others. Then, to analyze tones of arguments, all the paragraphs were divided into two types of tones, Positive tone and Negative tone. To identify and classify all of the tones of paragraphs and articles we had collected, supervised learning technique was used. The Na$\ddot{i}$ve Bayesian classifier algorithm provided in the MALLET package was used to classify all the paragraphs in articles. After classification, Precision, Recall and F-value were used to evaluate the results of classification. Based on the results of this study, three subjects such as Culture, Eco-business and Politics showed some differences in contents and tones of arguments among these three newspapers. In addition, for the National issues, tones of arguments on 4-major-rivers project were different from each other. It seems three newspapers have their own specific tone of argument in those sections. And keyword-networks showed different shapes with each other in the same period in the same section. It means that frequently appeared keywords in articles are different and their contents are comprised with different keywords. And the Positive-Negative classification showed the possibility of classifying newspapers' tones of arguments compared to others. These results indicate that the approach in this study is promising to be extended as a new tool to identify the different tones of arguments of newspapers.

• Journal of Korean Medicine Rehabilitation
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• v.18 no.4
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• pp.103-120
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• 2008

Objectives : This study aims to educate clinical doctors of the valuable practice of Manipulative Therapy(MT) as an opportunity for evidence-based medicine. Consequently it also serves to review the effectiveness and safety of MT. Methods : The literature studies of overseas were done by Cochrane Library and Medline website; those of domestic researches were completed by utilizing the sources which are gained from KERIS, KISS, DBpia, Kisti, and domestic institutes related with MT. Results : Eight papers related to the effectiveness of MT were published in South Korea, which concluded with the positive effects of MT. None of them are, however, well-designed randomized controlled trials(RCT). On the other hand, fifteen cases of nine articles indicate the adverse reaction of MT, and numbers of the researches in overseas revealed the side effects of MT in order of cervical, lumbar, and thoracic vertebrae. A vascular adverse reaction such as vertebral and carotid artery dissection was a highly reported cervical adverse reaction; in the thoracic and lumbar regions, neurological adverse reaction in terms of disc hemiation was frequently discovered. Conclusions : Henceforth, highly qualitative studies are required developing the effective outcomes and preventing any possible complications of MT. Therefore, systemic curriculums in institutions and sufficient clinical training in the filed are strongly recommended.

• Korean Journal of Environmental Agriculture
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• v.36 no.2
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• pp.87-96
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• 2017

BACKGROUND: The objective of this study was to identify and compare the main phenolic compounds (anthocyanins, flavonoids, phenolic acids) in blueberry and black raspberry cultivated in Korea using ultra-performance liquid chromatography diode array detection-quadrupole time-of-flight mass spectrometry (UPLC-DAD-QTOF/MS). METHODS AND RESULTS: Twenty-nine flavonoids were identified by comparison of ultraviolet and mass spectra with data in a chemical library and published data. Blueberry contained flavonols including kaempferol, quercetin, isorhamnetin, myricetin, and syringetin aglycones. Isorhamnetin 3-O-robinobioside, kaempferol 3-O-(6"-O-acetyl)glucoside, quercetin, quercetin 3-O-arabinofuranoside (avicularin), quercetin 3-O-(6''-O-malonyl) glucoside, and quercetin 3-O-robinobioside were detected for the first time in blueberry. The flavonoids in raspberry consisted of quercetin aglycone and its glycosides. The mean total flavonoid content in blueberry [143.0 mg/100 g dry weight (DW)] was 1.5-times that in raspberry (95.4 mg/100 g DW). The most abundant flavonoid in blueberry was quercetin 3-O-galactoside (hyperoside, up to 76.1 mg/100 g DW) and that in raspberry was quercetin 3-O-glucuronide (miquelianin, up to 55.5 mg/100 g DW). Miquelianin was not detected in blueberry. CONCLUSION: Flavonol glycosides were the main flavonoids in blueberry and black raspberry cultivated in Korea. The composition and contents of flavonoids differed between blueberry and black raspberry, and may be affected by the cultivar and cultivation conditions.

• BMB Reports
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• v.32 no.5
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• pp.461-467
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• 1999

Recombinant Mycobacterium smegmatis expressing ovalbumin was used to immunize C57BL/6(H-$2^b$) mice, and the humoral immunity against recombinant ovalbumin was analyzed. Antibodies were purified by denatured ovalbumin-conjugated affinity chromatography. The epitopes of the antibodies were screened with a random peptide library displayed on the tip of fUSE5 filamentous phage pIII minor coat proteins. Two peptides, IRLADR and SPGAEV, were selected predominantly by the recognition of purified antibodies using biopanning methods. The composition of the peptide sequence with the primary structure of OVA revealed that the peptide sequence analogizes to INEAGR, part of the $^{323}ISQAVHAAHAEINEAGR^{339}$ sequence previously reported as the antigenic determinant for murine Band also Th cell epitopes (I-$A^d$ binding). Also, the structures of these mimotopes obtained from restrained molecular dynamic computations resulted in the formation of a $\beta$-turn proven to be a secondary structure of the parent peptide within the ovalbumin molecule, enabling us to confirm the structural similarity. This study demonstrates that immunization with recombinant M. smegmatis can generate neutralizing antibodies identical with those induced by the administration of natural antigenic proteins and supports the potential use of mycobacteria as vaccine delivery vehicles.

• Journal of Korean Medicine Rehabilitation
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• v.33 no.2
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• pp.19-32
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• 2023

Objectives The purpose of this study is to systematically review the degree of pain and function improvement in acupuncture treatment for patellofemoral pain syndrome (PFPS). Methods Randomized controlled trials (RCTs) were searched from Medline/PubMed, Cochrane Library, Embase, WanFang Data, China National Knowledge Infrastructure (CNKI), Citation Information by NII (CiNII), Koreanstudies Information Service System (KISS), ScienceON, KoreaMed, and Korean Medical Database (KMbase). The methodological quality of selected RCTs' were evaluated according to Cochrane RoB2 tool. Results Total of 158 studies were identified and 7 RCTs were selected for systematic review. Frequently used evaluation method were visual analogue scale and Kujala scores. All studies showed significant effect on pain reduction and knee function between before and after treatment, but showed partial significance between the intervention and control group. Conclusions Research showed that acupuncture treatment is an effective treatment for improving the pain and function of PFPS, but it is difficult to conclude that it has a significant effect compared to other treatments. Selected studies included subjective evaluation indicators and the total of selected studies were small, so the interpretation of the results is limited. Also most of the included studies are evaluated to have some concerns of bias. Therefore, subsequent research should continously be done in more objective and systematic method.

• Journal of Pharmacopuncture
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• v.17 no.4
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• pp.7-14
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• 2014

Objectives: The purpose of this study is to analyze trends in domestic studies on pharmacopuncture therapy for treating cervical disease. Methods: This study was carried out on original copies and abstracts of theses listed in databases or published until July 2014. The search was made on the Oriental medicine Advanced Searching Integrated System (OASIS) the National Digital Science Library (NDSL), and the Korean traditional knowledge portal. Search words were 'pain on cervical spine', 'cervical pain', 'ruptured cervical disk', 'cervical disc disorder', 'stiffness of the neck', 'cervical disk', 'whiplash injury', 'cervicalgia', 'posterior cervical pain', 'neck disability', 'Herniated Nucleus Pulposus (HNP)', and 'Herniated Intervertebral Disc (HIVD)'. Results: Twenty-five clinical theses related to pharmacopuncture were selected and were analyzed by year according to the type of pharmacopuncture used, the academic journal in which the publication appeared, and the effect of pharmacopuncture therapy. Conclusion: The significant conclusions are as follows: (1) Pharmacopunctures used for cervical pain were Bee venom pharmacopuncture, Carthami-flos pharmacopuncture, Scolopendra pharmacopuncture, Ouhyul pharmacopuncturen, Hwangryun pharmacopuncture, Corpus pharmacopuncture, Soyeom pharmacopuncture, Hwangryunhaedoktang pharmacopuncture, Shinbaro phamacopuncture. (2) Randomized controlled trials showed that pharmacopuncture therapy combined with other methods was more effective. (3) In the past, studies oriented toward Bee venom pharmacopuncture were actively pursued, but the number of studies on various other types of pharmacopuncture gradually began to increase. (4) For treating a patient with cervical pain, the type of pharmacopuncture to be used should be selected based on the cause of the disease and the patient's condition.