• Archives of Pharmacal Research
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• v.20 no.5
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• pp.465-470
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• 1997

The human cDNA clone UDPGTh2, encoding a liver UDP-glucuronosyltransferase (UDPGT), was isolated from a .gamma.gt 11 cDNA library by hybridization to mouse transferase cDNA clone, UDPGTm1. The two clones had 74% nlicleotide sequence identities in the coding region. UDPGTh2 encoded a 529 amino acid protein with an amino terminus membrane-insertion signal peptide and a carboxyl terminus membrane-spanning region. In order to establish substrate specificity, the clone was inserted into the pSVL vector (pUDPGTh2) and expressed in COS 1 cells. Sixty potential substrates were tested using cells transfected with pUDPGTh2. The order of relative substrate activity was as follows: 4-hydroxyestrone > estriol >2-hydroxyestriol > 4-hydroxyestradiol > $6{\alpha}$-hydroxyestradiol >$5{\alpha}$-androstane-$3{\alpha}$, $11{\beta}$, $17{\beta}$-triol=5${\beta}$-androstane-$3{\alpha}$ ${\beta}$, $17{\beta}$-triol. There were only trace amounts of gulcuronidation of 2-hydroxyestradiol and 2-hydroxyestrone, and in contrast to other cloned transferase, no gulcuronidation of either the primary estrogens and androgens (estrone, $17{\beta}$estradiol/testosterone, androsterone) or any of the exogenous substrates tested was detected. A lineweaver-Burk plot of the effect of 4-hydroxystrone concentration on the velocity of glucuronidation showed an apparent Km of $13{\mu}M$. The unique specificity of this transferase might play an important role in regulating the level and activity of these potent and active estrogen metabolites.

• Journal of Korean Medicine Rehabilitation
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• v.28 no.4
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• pp.11-20
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• 2018

Objectives To systematically explore the effects of acupuncture treatment for rotator cuff disorders and review the clinical trials. Methods We searched 9 electronic databases (PubMed, Cochrane central, Embase, China National Knowledge Infrastructure [CNKI], Korea Institute of Science and Technology Information [KISTI], National Digital Science Library [NDSL], Korean studies Information Service System [KISS], Research Information Sharing Service [RISS], Oriental Medicine Advanced Searching Integrated System [OASIS]) to find randomized controlled trials that used acupunture treatment for rotator cuff disorders. We assessed the designs of the randomized controlled trials and the method of acupuncture treatment according to the Standards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA). The methodological quality of randomized controlled trials were assessed using the Cochrane Risk of Bias (RoB) tool. Results Total 5 trials were reviewed. 4 out of 5 randomized clinical trials reported meaningful effects of acupuncture treatments compared to control group. However risk of bias seemed high. Conclusions Although the results suggest that acupuncture treatment has favorable effects for rotator cuff disorders, most of the studies included methodologically high risk of bias. Thus, well designed randomized clinical trials which evaluate the effects of acupuncture treatment for rotator cuff disorders should be encouraged.

• Journal of Korean Traditional Oncology
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• v.17 no.2
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• pp.1-16
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• 2012

Background : Integrative cancer treatment is a holistic approach embracing body, mind, and spirit incorporating conventional treatments of surgery, chemotherapy, radiation and personalized complementary treatments. Wheel Balance Therapy (WBT) of East-West Cancer Center(EWCC), Dunsan Oriental Hospital of Daejeon University was developed to balance out all factors involved in cancer care based on the traditional theories of oriental medicine. Objective : This work aims to analytically review literatures on WBT and its related components. Methods : Literatures published from January 1st, 1990 to April 30th, 2011 were reviewed focusing on 4 main components of WBT; herbal medicine, immune activation, anti-cancer diet, and breathing/meditation. Data were retrieved from medical search engines and electronic data bases including Pubmed, Research Information sharing Service (RISS), Korean-studies Information Service System (KISS), China National Knowledge Infrastructure (CNKI), and Korea's National Digital Library (KNDL). Results : In this review, EWCC's most commonly prescribed formulas are explored. The composition of the formulas, their use in clinical settings as well as the background studies and other therapeutic efficacies are explained. Information on incorporating anti-cancer dietary support and breathing and meditation techniques, other therapies practiced as part of the center's integrative cancer care are also covered. Conclusion : WBT based on holistic theories of oriental medicine embracing body, mind, and spirit is expected to further contribute in promotion of cancer patients' quality of life and prolonged survival time.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2019.05a
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• pp.436-438
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• 2019

Air hockey robots are machine vision systems that allow users to play hockey balls through the camera. The position detection of the hockey ball is realized by using the color information of the ball using OpenCV library. It senses the position of the hockey ball, predicts its trajectory, and sends the result to the ARM Cortex-M board. The ARM Cortex-M board controls a 2- Axis Cartesian Coordinate Robot to run an air hockey game. Depending on the strategy of the air hockey robot, it can operate in defensive, offensive, defensive and offensive mode. In this paper, we describe a vision system development and trajectory prediction system and propose a new method to control a biaxial orthogonal robot in an air hockey game.

• Korean Journal of Ecology and Environment
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• v.56 no.4
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• pp.339-347
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• 2023

Dissolved organic matter (DOM) is a key component in the biogeochemical cycling in freshwater ecosystem. However, it has been rarely explored, particularly complex river watershed dominated by natural and anthropogenic sources, such as various effluent facility and livestock. The current research developed a new analytical method for TOC/TN (Total Organic Carbon/Total Nitrogen) stable isotope ratio, and distinguish DOM source using stable isotope value (δ¹³C-DOC) and spectroscopic indices (fluorescence index [FI] and biological index [BIX]). The TOC/TN-IR/MS analytical system was optimized and precision and accuracy were secured using two international standards (IAEA-600 Caffein, IAEA-CH-6 Sucrose). As a result of controlling the instrumental conditions to enable TOC stable isotope analysis even in low-concentration environmental samples (<1 mgC L^-1), the minimum detection limit was improved. The 12 potential DOM source were collected from watershed, which includes top-soils, groundwater, plant group (fallen leaves, riparian plants, suspended algae) and effluent group (pig and cow livestock, agricultural land, urban, industry facility, swine facility and wastewater treatment facilities). As a result of comparing characteristics between 12 sources using spectroscopic indices and δ¹³C-DOC values, it were divided into four groups according to their characteristics as a respective DOM sources. The current study established the TOC/TN stable isotope analyses system for the first time in Korea, and found that spectroscopic indices and δ¹³C-DOC are very useful tool to trace the origin of organic matter in the aquatic environments through library database.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.38 no.1
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• pp.33-42
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• 2001

Recently, the interests in the 3D image, generated from the range data and CAD, have exceedingly increased, accordingly a various 3D image database is being constructed. The efficient and fast scheme to access the desired image data is the important issue in the application area of the Internet and digital library. However, it is difficult to manage the 3D image database because of its huge size. Therefore, a proper descriptor is necessary to manage the data efficiently, including the content-based search. In this paper, the proposed shape descriptor is based on the voxelization of the 3D image. The medial axis transform, stemming from the mathematical morphology, is performed on the voxelized 3D image and the graph, which is composed of node and edge, is generated from skeletons. The generated graph is adequate to the novel shape descriptor due to no loss of geometric information and the similarity of the insight of the human. Therefore the proposed shape descriptor would be useful for the recognition of 3D object, compression, and content-based search.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2009.10a
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• pp.393-396
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• 2009

This paper describes a design of variable-length FFT/IFFT processor for OFDM-based communication systems. The designed FFT/IFFT processor adopts the in-place single-memory architecture, and uses a hybrid structure of radix-4 and radix-2 DIF algorithms to accommodate FFT lengths of $N=64{\times}2^k$ ($0{\leq}k{\leq}7$). To achieve both memory size reduction and the improved SQNR, a two-step conditional scaling technique is devised, which conditionally scales the intermediate results of each computational stage. The performance analysis results show that the average SQNR's of 64~8,192-point FFT's are over 60-dB. The processor synthesized with a $0.35-{\mu}m$ CMOS cell library can operate with 75-MHz@3.3-V clock, and 64-point and 8,192-point FFT's can be computed in $2.55-{\mu}s$ and $762.7-{\mu}s$, respectively, thus it satisfies the specifications of wireless LAN, DMB, and DVB systems.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2009.05a
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• pp.661-664
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• 2009

Recently, intelligent surveillance camera systems are needed popularly. However, current researches are focussed on improvement of a single module rather than implementation of an integrated system. In this paper, we implemented a moving wireless surveillance camera system which is composed of face detection, and using motion sensor. In our implementation, we used a camera module from SHARP, a pair of wireless video transmission module from ECOM, body of moving robot used for A4WD1 Combo kit for RC, a pair of ZigBee RF wireless transmission module from ROBOBLOCK, and a motion sensor module (AMN14111) from PANASONIC. We used OpenCV library for face dection and MFC for implement software. We identified real-time operations of face detection, PTT control, and motion sensor detecton. Thus, the implemented system will be useful for the applications of remote control, human detection, and using motion sensor.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.49 no.3
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• pp.21-29
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• 2012

This paper presents optimized searching technique to improve the performance of H.264/AVC. By using the proposed forward and backward searching algorithm, redundant cycles of latency for data reordering can be removed. Furthermore, in order to reduce the total number of execution cycles of CAVLC encoder, early termination mode and two stage pipelined architecture are proposed. The experimental result shows that the proposed architecture needs only 36.0 cycles on average for each $16{\times}16$ macroblock encoding. The proposed architecture improves the performance by 57.8% than that of previous designs. The proposed CAVLC encoder was implemented using Verilog HDL and synthesized with Magnachip $0.18{\mu}m$ standard cell library. The synthesis result shows that the gate count is about 17K with 125Mhz clock frequency.

• Women's Health Nursing
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• v.30 no.1
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• pp.41-55
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• 2024

Purpose: This review explored the status of publications on intimate partner violence (IPV) against pregnant women in contemporary China. Methods: The PubMed, Cochrane Library, Embase, CINAHL, and PsycInfo databases were searched using the terms "IPV," "pregnant woman," "Chinese," and synonyms in English, along with related keywords for Chinese publications. All literature pertaining to IPV during pregnancy, conducted in China, and published between 1987 and September 2023 was included. Results: A total of 37 articles from 30 studies were selected. The prevalence of IPV during pregnancy ranged from 2.5% to 31.3%, with psychological violence being the most common form. Frequently identified risk factors included unintended pregnancy, poor family economic conditions, male partners engaging in health risk behaviors, poor employment status of women or their partners, low education levels among women, physical or mental health issues, strained couple relationships, and in-law conflicts. IPV during pregnancy primarily led to mental health problems for the victims and could result in adverse obstetric outcomes, as well as negative effects on the temperament and development of the offspring. Victims in China demonstrated a low willingness to seek help from professionals. Furthermore, relevant research in mainland China is scarce, with a limited number of studies and non-standardized research methodologies. Conclusion: Future research should investigate IPV in pregnancy from various perspectives, identify factors unique to IPV during pregnancy, and focus on high-risk groups. Considering the conditions in China, there is a pressing need to increase public awareness of IPV and to investigate interventions aimed at addressing this issue.