• Environmental Analysis Health and Toxicology
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• v.22 no.3
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• pp.235-245
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• 2007

Toxicity of nonlyphenol (NP) one of EDCs was studied with focus on reproduction of the crucian carp, Carassius auratus. Fishes were cultured under control and nonylphnol exposure conditions for 32 weeks. Experimental group was composed of total of 4 groups, 1 control condition and 3 nonylphenol exposure condition ($18\;{\mu}g\;NP\;L^{-1},\;37\;{\mu}g\;NP\;L^{-1}\;and\;83\;{\mu}g\;NP\;L^{-1}$). Survival rate was found to be similar in control and $18\;{\mu};NP\;L^{-1}$. However, it is lower In the $37\;{\mu};NP\;L^{-1}$ and $83\;{\mu};NP\;L^{-1}$ in comparison to the control group. Deformation of gonads was the highest in the exposure condition of $18{\mu};NP\;L^{-1}$ with the female illustrating higher ratio than the male. GSI was not much different in the male but in the female, NP exposure group illustrated lower value compared to the control group. HSI and GI did not illustrate any clear differences between the control and exposure group for both male and female. Intersex was 0% in the wild group, 4.16% in the laboratory control group, and 25.67% in the NP exposure condition with female illustrating higher compared to male. Concentration of blood vitellogenin in female illustrated no clear differences between the control and NP exposure group. However, in the male, it was higher in the NP exposure group in comparison to the control group, and illustrated higher values of vitellogenin compared to the figures found in the female of same con-centration condition.

• Advances in concrete construction
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• v.8 no.2
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• pp.119-126
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• 2019

This paper reports an experimental investigation conducted to evaluate the durability performance of concrete mixtures prepared utilizing blends of Type I Portland cement (OPC) and natural pozzolans (NPs) obtained from three different sources in Saudi Arabia. The control concrete mixture containing OPC alone as the binder and three concrete mixtures incorporating NPs were prepared keeping water/binder ratio of 0.4 (by weight), binder content of $370kg/m^3$, and fine/total aggregate ratio of 0.38 (by weight) invariant. The compressive strength and durability properties that included depth of water penetration, depth of carbonation, chloride diffusion coefficient, and resistance to reinforcement corrosion and sulfate attack were determined. Results of this study indicate that at all ages, the compressive strength of NP-admixed concrete mixtures was slightly less than that of the concrete containing OPC alone. However, the concrete mixtures containing NP exhibited lower depth of water penetration and chloride diffusion coefficient and more resistance to reinforcement corrosion and sulfate attack as compared to OPC. NP-admixed concrete showed relatively more depth of carbonation than OPC when subjected to accelerated carbonation. The results of this investigation indicates the viability of utilizing of Saudi natural pozzolans for improving the durability characteristics of concrete subjected to chloride and sulfate exposures.

• BMB Reports
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• v.35 no.3
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• pp.313-319
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• 2002

N-Acetyl-$\beta$-D-hexosaminidase ($\beta$-HexNAc'ase) (EC 3.2.1.52) was purified from rice seeds (Oryza sative L. var. Dongjin) using ammonium sulfate (80%) precipitation, Sephadex G-150, CM-Sephadex, and DEAE-Sephadex chromatography, sequentially. The activities were separated into 7 fractions($F_1-F_7$) by CM-Sephadex chromatography. Among them, F6 was further purified to homogeneity with a 13.0% yield and 123.3 purification-fold. The molecular mass was estimated to be about 52 kDa on SDS-PAGE and 37.4 kDa on Sephacryl S-300 gel filtration. The enzyme catalyzed the hydrolysis of both p-nitrophenyl-N-acetyl-$\beta$-D-hexosaminide (pNP-GlcNAc) and p-nitrophenyl-N-acetyl-$\beta$-D-hexosaminide (pNP-GalNAc) as substrates, which are typical properties of $\beta$-HexNAc'ase. The ratio of the pNP-GlcNAc'ase activity to the pNP-GalNAc'ase activity was 4.0. However, it could not hydrolyze chitin, chitosan, pNP-$\beta$-glucopyranoside, or pNP-$\beta$-glucopyranoside. The enzyme showed $K_m$, $V_{max}$ and $K_{cat}$ for pNP-GlcNAc of 1.65 mM, $79.49\;mM\;min^{-1}$, and $4.79{\times}10^6\;min^{-1}$, respectively. The comparison of kinetic values for pNP-GlcNAc and pNP-GalNAc revealed that the two enzyme activities are associated with a single binding site. The purified enzyme exhibited optimum pH and temperature for pNP-GlcNAc of 5.0 and $50^{\circ}C$, respectively. The enzyme activity for pNP-GlcNAc was stable at pH 5.0-5.5 and $20-40^{\circ}C$. The enzyme activity was completely inhibited at a concentration of 0.1 mM $HgCl_$ and $AgNO_3$, suggesting that the intact thiol group is essential for activity. Chloramine T completely inhibited the activity, indicating the possible involvement of methionines in the mechanism of the enzyme.

• Applied Chemistry for Engineering
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• v.28 no.2
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• pp.186-192
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• 2017

In this study, water in oil (W/O) emulsion fuel was prepared with surfactant mixture of OIMS90 and NP12 by varying ratio of water to bunker-C oil, surfactant concentration and composition, emulsification time, stirring intensity, temperature and mixing time. Diesel engine performance and exhaust emissions were measured and analyzed with prepared emulsified fuel and compared with those measured using bunker Coil. The results indicated that bunker C emulsion fuel stabilized by surfactant mixture of OIMS90 and NP12 is efficient in reducing emissions of particulate matter, $NO_2$, CO, $CO_2$ and $SO_2$. The biggest reduction in exhaust emission was achieved by using emulsion fuel prepared by OIMS90/NP12 = 4 : 6, 500 ppm of total surfactant concentration and 10% water content at $80^{\circ}C$. Boiler efficiency test measured with emulsion fuel showed excellent energy efficiency compared with bunker C oil.

• Bulletin of the Korean Chemical Society
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• v.33 no.9
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• pp.3009-3016
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• 2012

This study evaluated the use of iron-impregnated SBA-15 (Fe/SBA-15) as a catalyst for the oxidative degradation of persistent phenol analogues, such as 2-chlorophenol (2-CP), 4-chlorophenol (4-CP), 2-nitrophenol (2-NP), 4-nitrophenol (4-NP) and 2,4,6-trichlorophenol (2,4,6-TCP) in water. The oxidation reactions were carried out with reaction time, concentration of the phenols, amount of the catalysts, reaction temperature, pH of the reaction mixture as the process variables with or without using hydrogen peroxide as the oxidizing agent. The conversion achieved with Fe/SBA-15 at 353 K for 2-CP, 4-CP, 2-NP, 4-NP, 2,4,6-TCP was 80.2, 71.2, 53.1, 62.8, 77.3% in 5h with a reactant to $H_2O_2$ mole ratio of 1:1, and 85.7, 65.8, 61.9, 63.7, 78.1% in the absence of $H_2O_2$, respectively. The reactions followed pseudo first order kinetics. The leachability study indicated that the catalyst released very little iron into water and therefore, the possibility of secondary pollution is negligible.

• Nuclear Engineering and Technology
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• v.41 no.6
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• pp.765-774
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• 2009

For over 30 years, investigations of the thermohydraulic behavior of pressurized-water reactors under accident conditions have been carried out in the PKL test facility at AREVA NP in Erlangen, Germany. The PKL facility models the entire primary side and significant parts of the secondary side of a of pressurized water reactor at a height scale of 1:1. Volumes, power ratings and mass flows are scaled with a ratio of 1:145. The experimental facility consists of four primary loops with circulation pumps and steam generators (SGs) arranged symmetrically around the reactor pressure vessel (RPV). The investigations carried out encompass a very broad spectrum from accident scenario simulations with large, medium, and small breaks, over the investigation of shutdown procedures after a wide variety of accidents, to the systematic investigation of complex thermohydraulic phenomena. The PKL tests began in the mid 1970s with the support of the German Research Ministry. Since the mid 1980s, the project has also been significantly supported by the German PWR operators. Since 2001, 25 partner organizations from 15 countries have taken part in the PKL investigations with the support and mediation of the OECD/ NEA (Nuclear Energy Agency). After an overview of PKL history and a short description of the facility, this paper focuses on the investigations carried out since the beginning of the international cooperation, and shows, by means of some examples, what insights can be derived from the tests.

• Journal of Korea Multimedia Society
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• v.19 no.2
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• pp.443-450
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• 2016

This paper deals with a kind of packing problem of which the goal is to compose one or more templates which will be used to produce the items of different types. Each template consists of a fixed number of slots which are assigned to the different types of items and the production of the items is accomplished by printing the template repeatedly. The objective is to minimize the total number of produced items. This problem is known to be NP-hard. We present a polynomial time approximation algorithm which has a constant approximation ratio. The proposed algorithm is based on the well-known first-fit strategy.

• Journal of Power Electronics
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• v.14 no.3
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• pp.531-540
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• 2014

A novel carrier-based PWM (CBPWM) strategy of a three-level NPC converter is proposed in this paper. The novel strategy can eliminate the low-frequency neutral point (NP) voltage oscillation under the entire modulation index and full power factor. The basic principle of the novel strategy is introduced. The internal modulation wave relationship between the novel CBPWM strategy and traditional SPWM strategy is also studied. All 64 modulation wave solutions of the CBPWM strategy are derived. Furthermore, the proposed CBPWM strategy is compared with traditional SPWM strategy regarding the output phase voltage THD characteristics, DC voltage utilization ratio, and device switching losses. Comparison results show that the proposed strategy does not cause NP voltage oscillation. As a result, no low-frequency harmonics occur on output line-to-line voltage and phase current. The novel strategy also has higher DC voltage utilization ratio (15.47% higher than that of SPWM strategy), whereas it causes larger device switching losses (4/3 times of SPWM strategy). The effectiveness of the proposed modulation strategy is verified by simulation and experiment results.

• Korean Journal of Ecology and Environment
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• v.41 no.1
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• pp.81-89
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• 2008

The eco-toxicological effects of endocrine disrupter, 4-nonylphenol (4NP) were observed and detected on the harpacticoid copepod, Tigriopus japonicus s.l. obtained and cultur-ed from our coast. There were no significant differences survival rate, sex ratio, and fecundity on T. japonicus s.l. at as low as $30{\mu}gL^{-1}$ of 4 NP exposure. Whereas, 4NP induced developmental delay, decreasing biomass and body size of nauplius and copepodite. Also, Differentially Expressed Gene (DEG) was conducted to detecting gene expression for potential biomarkers response to 4NP. As a result, full lifecycle research on morphology and gene expression of T. japonicus s.l. suggested potential bioindicators or biomarkers for environmental monitoring and assessments.

• Development and Reproduction
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• v.23 no.3
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• pp.263-275
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• 2019

Based on our preliminary results, we examined the possible role of low-dose and chronic-exposing of the chemicals those are known as endocrine disrupting chemical (EDC), on the proliferation of uterine endometrium and the localization of steroid receptors. Immunohistochemical or immunofluorochemical methodology were employed to evaluate the localization of antigen identified by monoclonal antibody Ki 67 protein (MKI67), estrogen receptor 1 (ESR1), estrogen receptor 2 (ESR2), and progesterone receptor (PGR). In $133{\mu}g/L$ and $1,330{\mu}g/L$ di(2-ethylhexyl) phthalate (DEHP) and $50{\mu}g/L$ nonylphenol (NP) groups, the ratio of MKI67 positive stromal cells was significantly increased but not in $500{\mu}g/L$ NP group. The ratios of MKI67 positive glandular and luminal epithelial cells were also changed by the chronic administration of NP and DEHP in tissue with dose specific manner. ESR1 signals were localized in nucleus in glandular and luminal epithelia of control group but its localization was mainly in cytoplasm in DEHP and NP administered groups. On the other hand, it was decreased at nucleus of stromal cells in $1,330{\mu}g/L$ DEHP group. The colocalization patterns of these nuclear receptors were also modified by the administration of these chemicals. Such a tissue specific and dose specific localization of ESR2 and PGR were detected as ESR1 in all the uterine endometrial tissues. These results show that the chronic lows-dose exposing of NP or DEHP modify the localization and colocalization of ESRs and PGR, and of the proliferation patterns of the endometrial tissues.