• International Journal of Fluid Machinery and Systems
• /
• v.9 no.4
• /
• pp.307-312
• /
• 2016

The present study reported of the use of special shaped blade to reduce the difference in pressure across the Wells turbine for wave energy conversion. The blade profile was composed of NACA0020 airfoils and trailing edge was notched like chevron. Experiments were performed investigating the influence of trailing edge shape on the turbine performance. Four notch depths were used to investigate the effect of depth of cut on the turbine performance. As results, by placing a notch-cut at the trailing edge of the blade, it was possible to reduce the pressure difference across the turbine without lowering the efficiency. In addition, the pressure difference substantially reduced at a constant rate with the increase of the cut ratio.

• Journal of Ocean Engineering and Technology
• /
• v.12 no.1
• /
• pp.23-31
• /
• 1998

Kind 1 propeller shaft in ships is the shaft which is provided with effective measures against corrosion by sea water, or the shaft which is made of approved corrosion resistance materials. The propeller shaft other than specified above is Kind 2. Thus, this study is mainly concerned with the resistance to fatigue damage in sea water against stress concentrations due to the notches. The results obtained can be summarized as follows; (1) The stress increases with curing time, however, when the curing time reaches at 96 hours the stress becomes a constant value. The elongation decreases with curing time, however, when the curing time reaches at 48 hours the elongation becomes a constant value. Thus, in case of FRP coating on propeller shaft, it is necessary to cure for 48 hours at least. (2) The relation of $\sigma$$_n$-K$_t$ is to be classified into two parts, which is a part where fracture nominal stress, $\sigma$$_n$, decreases with increasing $K_t$, and a part where $\sigma$$_n$ is nearly constant independent of $K_t$. (3) According to a linear notch mechanics, the measure of severity controlling the fracture in notched FRP body is the notch root radius, $\rho$. The notched static strength of an arbitrary specimen will be estimated from $\sigma$$_{max}$ -1/$\rho$ curve. (4) Through the observation of cross section after fatigue test, the part of interface was kept good condition irrespective of loading conditions.

• Molecules and Cells
• /
• v.45 no.5
• /
• pp.329-342
• /
• 2022

The liver is the predominant metastatic site for pancreatic cancer. However, the factors that determine the liver metastasis and the specific molecular mechanisms are still unclear. In this study, we used human pancreatic cancer cell line Hs766T to establish Hs766T-L3, a subline of Hs766T with stable liver metastatic ability. We performed RNA sequencing of Hs766T-L3 and its parental cell line Hs766T, and revealed huge differences in gene expression patterns and pathway activation between these two cell lines. We correlated the difference in pathway activation with the expression of the four core transcriptional factors including STAT1, NR2F2, GATA2, and SMAD4. Using the TCGA database, we examined the relative expression of these transcription factors (TFs) in pan-cancer and their relationship with the prognosis of the pancreatic cancer. Among these TFs, we considered GATA2 is closely involved in tumor metastasis and may serve as a potential metastatic driver. Further in vitro and in vivo experiments confirmed that GATA2-mediated transcriptional activation of Notch3 promotes the liver metastasis of Hs766T-L3, and knockdown of either GATA2 or Notch3 reduces the metastatic ability of Hs766T-L3. Therefore, we claim that GATA2 may serve as a metastatic driver of pancreatic cancer and a potential therapeutic target to treat liver metastasis of pancreatic cancer.

• The Journal of Korean Academy of Prosthodontics
• /
• v.43 no.1
• /
• pp.41-51
• /
• 2005

Statement of problem. Anatomic landmarks have been used in the orientation of occlusal plane and the determination of vertical dimension for edentulous patients. Such as labial vestibules of anterior region and hamular notches, retromolar pads of posterior region are very useful anatomic landmarks for fabrication of occlusion rim because they are to be identified on master casts. Therefore, if average distances between landmarks of maxillae and mandible in dentate subjects are measured and applied, not only occlusal plane but also vertical dimension can be established initially. Purpose. The purpose of this study is to measure vertical distances between anatomic landmarks and to present a guide to the orientation of occlusal plane and the determination of vertical dimension of edentulous patients. Material and method. Upper and lower border-molded casts were made in 93 Korean dentulous subjects, mean age 25 years. Incisal edges of central incisors, bottoms of labial vestibules, hamular notches and the half level of retromolar pads were marked on casts. Measurements of vertical distances from incisal edge of central incisor to the bottom of labial vestibule, between upper and lower bottoms of labial vestibules, from hamular notch to retromolar pad and from hamular notch to the occlusal plane established by the incisal edge of maxillary central incisor and mesiopalatal cusps of both maxillary first molars were made on each cast. Results and conclusion. 1. The mean distance from the incisal edge of central incisor to the bottom of labial vestibule was 20.8mm(SD 1.7) on upper casts and 17.3mm(SD 1.4) on lower casts. 2. The mean distance between both bottoms of labial vestibules of upper and lower casts was 35.0mm(SD 2.7). 3 The mean distance from hamular notch to the half level of retromolar pad was 5.0mm(SD 1.3). 4. The mean distance from hamular notch to occlusal plane was 7.9mm(SD 1.5). 5. Distances from incisal edge of central incisor to labial vestibule on lower casts(P<0.01) and from hamular notch to retromolar pad(P<0.0001) were greater in male than in female.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.25 no.9
• /
• pp.886-894
• /
• 2014

A wideband bow-tie antenna fed by wideband microstrip-coplanar stripline(CPS) balun and band notch structures that can be applied to bow-tie antenna are proposed in this paper. In order to increase bandwidth, bow-tie radiators are reshaped so that the surface current flows continuously, and wideband impedance matching is achieved by adjusting strip width and spacing of CPS feeding line. The VSWR is measured as 2:1 over the wide frequency range of 2.3~12 GHz. The fabricated antenna size is $60mm{\times}60mm$. In order to achieve the band-notch function at WLAN(5.8 GHz), ${\lambda}/4$ folded-slits located ${\lambda}/4$ away from feeding point are utilized. To minimize the slit size, folded-slit type is adopted. The measured VSWR is 7:1 and gain attenuation is 14 dB at 5.8 GHz.

• Journal of Periodontal and Implant Science
• /
• v.30 no.2
• /
• pp.229-242
• /
• 2000

The purpose of this study was to evaluate the effect of fibrin tissue adhesive and porous resorbable calcium carbonate on the periodontal regeneration of the class II furcation defect in dogs. Class II furcation defect was surgically created on the second, third, and fourth premolars bilaterally in the mandibles of six mongrel dogs. The experimental sites were divided into four groups according to the treatment modalities: Control-surgical debridement only; Group I-calcium carbonate grafting; Group II-application of fibrin adhesive only; Group III-application of fibrin adhesive after calcium carbonate grafting. The animals were sacrificed at the 2, 4, and 12 weeks after periodontal surgery and the decalcified specimens were prepared for histological and histometrical examination. The results are as follows : Clinically, there were no inflammatory response in all groups after 2, 4, 12 weeks. In the Control group, junctional epithelium was grown downward to the reference notch. In Group I, graft materials were exfoliated from the defect throughout the experimenta periods andnew bone was seen in the notch area at 4 and 12 week specimens. In Group II, fibrin adhesive was absorbed at 2 week specimens, and connective tissue attachment increased than that of control group. New cementum and new bone were seen above the notch area. In Group III, the graft material was maintained in the defect throughout the experimental period and inducing the amount of periodontal tissue regeneration was higher than other groups. These results suggest that the use of fibrin tissue adhesive in conjunction with porous resorbable calcium carbonate would improves the stability of graft material and inhibit the epithelial down growth and make it be a feasible method for periodontal regeneration.

• Journal of the Korea Concrete Institute
• /
• v.16 no.6 s.84
• /
• pp.851-858
• /
• 2004

Purpose of this paper is to determine the appropriate size of a center notched disk specimen for mode I fracture toughness $K_{IC}$. For this purpose, mode I test results with various sizes of center notched disk were compared with the RILEM three-point-bend test ones. Compressive strength of concrete used in this paper was 44.9 MPa. Diameters of 200, 300, 400 mm, thickness of 75, 100, 125 mm, and notch length ratios an of 0.3, 0.4, 0.5, 0.6 were used for the mode I disk test. Also, diameter of 300mm thickness of 100mm, and notch length ratios a/R of 0.3, 0.4, 0.5, 0.6 were used for the mixed mode disk test. Mixed mode stress intensity factors were investigated by changing notch angles for the disk specimen. Stress intensity factors of a center notched disk were calculated with the various methods for comparison. From the test results, mode I fracture toughness calculated from the disk specimen with diameter of 300 mm, thickness of Inn and notch length ratio a/R of 0.5 was very similar to the RILEM three-point-bend test ones. And it is verified that stress intensity factors for mixed mode can be easily calculated with the disk specimen.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.10 no.4
• /
• pp.1-10
• /
• 1990

RILEM proposed three point bend test to determine the fracture energy of concrete, but there is discrepancy between the theoritical and the experimental fracture energy of concrete by the influence of self-weight of concrete. This paper presents four point bend test using proving ring in order to take into account the influence of self-weight of concrete. The initial notch to beam depth ratio was varied from 0.2 to 0.6 in order to investigate the variation of fracture energy of concrete according to the variation of initial notch depth. The proposed four point bend test using proving ring was verified to be superior to three point bend test.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.37 no.4
• /
• pp.511-519
• /
• 2013

Switching controllers for active magnetic bearings are claimed to minimize the copper losses because they do not use bias currents. In this study, we compare the performances of the switching controller with those of the widely used proportional-derivative (PD) controller. The PD controller is combined with a synchronous notch filter to reduce the effect of the unbalance disturbance. For a fair and objective comparison, the PD controller is designed systematically. The switching controller is designed so that the dynamics of the two controllers are almost identical. A system model is developed. This model includes the flexible modes of the rotor and the dynamics of the sensors and amplifiers. The simulation results show that the switching controller indeed reduces the copper loss at lower speeds. However, it fails to operate around the speed close to the bending mode of the rotor.

• International Journal of Aeronautical and Space Sciences
• /
• v.13 no.4
• /
• pp.491-498
• /
• 2012

A Ground Based Augmentation System (GBAS) is an enabling technology for an aircraft's precision approach based on a Global Navigation Satellite System (GNSS). However, GBAS is vulnerable to interference, so effective GNSS interference detection and mitigation methods need to be employed. In this paper, an intentional GNSS interference detection and characterization algorithm is proposed. The algorithm uses Automatic Gain Control (AGC) gain and adaptive notch filter parameters to classify types of incoming interference and to characterize them. The AGC gain and adaptive lattice IIR notch filter parameter values in GNSS receivers are examined according to interference types and power levels. Based on those data, the interference detection and characterization algorithm is developed and Monte Carlo simulations are carried out for performance analysis of the proposed method. Here, the proposed algorithm is used to detect and characterize single-tone continuous wave interference, swept continuous wave interference, and band-limited white Gaussian noise. The algorithm can be used for GNSS interference monitoring in an excessive Radio Frequency Interference environment which causes loss of receiver tracking. This interference detection and characterization algorithm will be used to enhance the interference mitigation algorithm.