• 제목/요약/키워드: NOR-3

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Endometrial Cancer in Hospital Universiti Sains Malaysia

  • Wan-Nor-Asyikeen, Wan Adnan;Siti-Azrin, Ab Hamid;Jalil, Nur Asyilla Che;Othman, Nor Hayati;Zain, Anani Aila Mat
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권6호
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    • pp.2867-2870
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    • 2016
  • Background: Endometrial cancer is the most common gynecological malignancy among females worldwide, approximately 320,000 women being diagnosed with the disease each year and 76,000 dying. To date, there is limited knowledge of endometrial cancer in Malaysia. Objectives: To identify the epidemiological profile and prognostic factors of survival. Materials and Methods: A list of endometrial cancer patients in 2000-2011 was obtained from the hospital Record Department. Only cases confirmed by histopathology examination were included. We excluded those with incomplete medical records or referral cases. Simple and multiple Cox regression approaches were used for data analysis. Results: Only 108 cases were included with a mean (SD) age of 62.7 (12.3) years, with 87.0% Malay ethnicity. Grade of cancer was: 29.1% grade 1, 43.7% grade 2 and 27.2% grade 3. The majority of patients had non-endometrioid type (60.2%), with myometrial invasion (82.2%) and lymphovascular invasion (57.3%). The significant prognostic factors were age (HR 1.05; 95% CI: 1.02, 1.08, p=0.002) and having lymphovascular invasion (HR 2.15; 95% CI: 1.08, 4.29; p=0.030). Conclusions: Endometrial cancer patients should be diagnosed earlier to reduce the risk of mortality. The public should be given education on the signs and symptoms of the disease.

$C_{18}$ and $C_{19}$ Quassinoids from Eurycoma Longifolia

  • Hideji Itokawa;Xu-Rong Qin;Hiroshi Morita;Koichi Takeya
    • 한국자원식물학회지
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    • 제7권1호
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    • pp.29-34
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    • 1994
  • Two new 1,2-seco-1-nor-6((5 $\mapsto$ 10)abeo-picrasan-2,5-olideskeleton quassinoids, eurylactones A [1] and B [2], and two new $C_{19}$ skeleton quassinoids 3 and 4 were isolated from Eurycoma longifolia together with two known $C_{18}$ quassinoids 5 and 6. Their sttuctures were established by the spectral evidence.Many quassinoids have already been isolated (1-3) from the roots, wood, and leaves of Eurycoma longiolia Jack (Simaroubaceae) and have been used as a folk medicine insoutheast Asia. As part of a series of studies, we have further undertaken the chemicalinvestigation of the n-BuOH-soluble fraction of the MeOH extract and isolated two new1,2-seco-1-nor-6(5 $\mapsto$ 10)abeo-picrasane skeleton quassinoids 1 and 2, which have beenknown only in shinjulactone B (4,5) and yadanfiolide (6), two new $C_{19}$-type quasslnolds3 and 4, and two known C18-type quassinoids 5 and 6. In this paper, the structureelucidation and biosenetic relation of these compounds are described.

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A REPRESENTATION FOR NONCOMMUTATIVE BANACH ALGEBRAS

  • PAK HEE CHUL
    • Journal of applied mathematics & informatics
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    • 제17권1_2_3호
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    • pp.591-603
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    • 2005
  • A representation for non-commutative Banach algebras is discussed, which generalizes the Gelfand representation for commutative Banach algebras and the Gelfand-Naimark representation for $C^{\ast}$-algebras. Its basic properties are also investigated. In appendix, an example of Banach algebra that is neither semi-simple nor radical is presented.

계육에서 분리한 Listeria species 와 Staphylococcus aureus의 항생제 내성패턴 (Antimicrobial resistance patterns of Listeria species and Staphylococcus aureus isolated from poultry carcasses in Korea)

  • 허진;김준만;권남훈;박건택;임지연;정우경;홍순근;박용호
    • 대한수의학회지
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    • 제44권2호
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    • pp.217-224
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    • 2004
  • This study was carried out to investigate the antibiotic resistance pattern of Listeria spp. and Staphylococcus aureus. A total of 17 (14.8%) L. monocytogenes, 13 (11.3%) L. innocua, 7 (7%) L. welshimeri, and 83 (72.2%) S. aureus were isolated from commercial poultry carcasses in Seoul and Kyonggi province during the period between 2001 and 2003. Antibiotic susceptibility test of all Listeria strains isolated was performed by the disk agar diffusion method. Antibiotics used in the study were as follows; Amikacin (An), Ampicillin (Am), Cephalothin (Cf), Chloramphenicol (C), Ciprofloxacin (Cip), Erythromycin (E), Gentamicin (Gm), Imipenem (Ipm), Kanamycin (K), Minocycline (Mi), Neomycin (N), Norfloxacin (Nor), Ofloxacin (Ofx), Penicillin (P), Streptomycin (S), Tetracycline (Te), Tobramycin (Nn), Trimethoprim (Tmp), Trimethoprim/Sulfamethoxazloe (Sxt), and Vancomycin (Va). The antibiotic resistance pattern of S. aureus isolates was performed by the disk agar diffusion method. For the latter program, antibiotics used to the study were as follows; Cf, C, Cip, Clindamycin (Cc), E, Gm, Ipm, Nafcillin (Nf), Oxacillin (Ox), P, Te, Sxt, and Va. Of the 17 L. monocytogenes isolates, 94.1% were resistant to Te, 88.2% to Mi, 11.8% to Nor, 11.8% to S, 5.9% to Cip, and 5.9% to C. Of 13 L. innocua, 53.8% were resistant to Te, 23.1% to Mi, 23.1% to S, 7.7% to Cip, and 7.7% to Nor. Of 7 L. welshimeri, 57.1% were resistant to Te, and 14.3% to Am. Of 83 S. aureus, 100% were resistant to Te, 86.7% to Gm, 34.9% to P, 15.7% to Cip, 12% to Cc, 9.6% to E. The multiple antibiotic resistance patterns of L. monocytogenes isolates were observed in Te Mi Cip (5.9%), Te Mi Nor (5.9%), Te Mi (76.5%), and Te Nor (5.9%). Multiple antibiotic resistance was also found in L. innocua isolates. Resistant to Te Mi S Cip Nor was 7.7%, Te Mi S (7.7%), Te Mi (7.7%), and was 7.7% to Te S. Antibiotic resistance patterns for S. aureus isolats were demonstrated to Te Gm P Cip Cc E (6.0%), Te Gm Cip Cc E (3.6%), Te Gm P Cc (1.2%), Te Gm P (15.6%), Te Gm Cip (2.4%), Te P Cip (2.4%), Te Gm Cc (1.2%), Te Gm (56.6%), Te P (9.6%), and to Te Cip (1.2%). The results of this study suggest a high incidence of Lsteria spp. and S. aureus on poultry carcasses. The contaminated poultry carcasses may be a potential vehicle for foodborne infections due to multiple antimicrobial resistant organisms.

MLC NAND-형 Flash Memory 내장 자체 테스트에 대한 연구 (MLC NAND-type Flash Memory Built-In Self Test for research)

  • 김진완;김태환;장훈
    • 전자공학회논문지
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    • 제51권3호
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    • pp.61-71
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    • 2014
  • 임베디드 시스템의 저장매체 시장의 플래시 메모리의 점유율이 증가되고 반도체 산업이 성장함에 따라 플래시 메모리의 수요와 공급이 큰 폭으로 증가하고 있다. 특히 스마트폰, 테블릿 PC, SSD등 SoC(System on Chip)산업에 많이 사용되고 있다. 플래시 메모리는 셀 배열 구조에 따라 NOR-형과 NAND-형으로 나뉘고 NAND-형은 다시 Cell당 저장 가능한 bit수에 따라서 SLC(Single Level Cell)과 MLC(Multi Level Cell)로 구분된다. NOR-형은 BIST(Bulit-In Self Test), BIRA(Bulit-In Redundancy Analysis)등의 많은 연구가 진행되었지만 NAND-형의 경우 BIST 연구가 적다. 기존의 BIST의 경우 고가의 ATE 등의 외부 장비를 사용하여 테스트를 진행해야한다. 하지만 본 논문은 MLC NAND-형 플래시 메모리를 위해 제안되었던 MLC NAND March(x)알고리즘과 패턴을 사용하며 내부에 필요한 패턴을 내장하여 외부 장비 없이 패턴 테스트가 가능한 유한상태머신(Finite State Machine) 기반구조의 MLC NAND-형 플래시 메모리를 위한 BIST를 제안하여 시스템의 신뢰도 향상과 수율향상을 위한 시도이다.

터널링 전계효과 트랜지스터로 구성된 3차원 적층형 집적회로에 대한 연구 (Study of monolithic 3D integrated-circuit consisting of tunneling field-effect transistors)

  • 유윤섭
    • 한국정보통신학회논문지
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    • 제26권5호
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    • pp.682-687
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    • 2022
  • 터널링 전계효과 트랜지스터(tunneling field-effect transistor; TFET)로 적층된 3차원 적층형 집적회로(monolithic 3D integrated-circuit; M3DIC)에 대한 연구 결과를 소개한다. TFET는 MOSFET(metal-oxide-semiconductor field-effect transistor)와 달리 소스와 드레인이 비대칭 구조이므로 대칭구조인 MOSFET의 레이아웃과 다르게 설계된다. 비대칭 구조로 인해서 다양한 인버터 구조 및 레이아웃이 가능하고, 그 중에서 최소 금속선 레이어를 가지는 단순한 인버터 구조를 제안한다. 비대칭 구조의 TFET를 순차적으로 적층한 논리 게이트인 NAND 게이트, NOR 게이트 등의 M3DIC의 구조와 레이아웃을 제안된 인버터 구조를 바탕으로 제안한다. 소자와 회로 시뮬레이터를 이용해서 제안된 M3D 논리게이트의 전압전달특성 결과를 조사하고 각 논리 게이트의 동작을 검증한다. M3D 논리 게이트 별 셀 면적은 2차원 평면의 논리게이트에 비해서 약 50% 감소된다.

에너지 효율이 우수한 XOR-XNOR 회로 설계 (Design of an Energy Efficient XOR-XNOR Circuit)

  • 김정범
    • 전기전자학회논문지
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    • 제23권3호
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    • pp.878-882
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    • 2019
  • XOR(exclusive-OR)-XNOR(exclusive NOR) 회로는 고 성능 산술 연산에 필요한 4-2 압축 회로(4-2 compressor)의 기본 구성 요소이다. 본 논문에서는 에너지 효율이 우수한 XOR-XNOR 회로를 제안한다. 제안한 회로는 임계 경로의 내부 기생 캐패시턴스를 감소시켜 전파 지연 시간을 감소시켰으며, 모든 입력 조합의 경우에 완벽한 출력 값을 가지며 8개의 트랜지스터로 설계되었다. 기존 회로와 비교하여 제안한 회로는 전파 지연 시간이 14.5% 감소하였으며, 전력 소모는 1.7% 증가하였다. 따라서 전력 소모와 지연 시간의 곱 (power-delay product: PDP)과 에너지와 지연 시간의 곱 (energy-delay product: EDP) 각각 13.1%, 26.0% 감소하였다. 제안한 회로는 0.18um CMOS 표준공정을 이용하여 설계하였으며 SPICE 시뮬레이션을 통해 타당성을 입증하였다.

Clustering Keywords to Define Cybersecurity: An Analysis of Malaysian and ASEAN Countries' Cyber Laws

  • Joharry, Siti Aeisha;Turiman, Syamimi;Nor, Nor Fariza Mohd
    • 아시아태평양코퍼스연구
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    • 제3권2호
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    • pp.17-33
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    • 2022
  • While the term is nothing new, 'cybersecurity' still seems to be defined quite loosely and subjectively depending on context. This is problematic especially to legal writers for prosecuting cybercrimes that do not fit a particular clause/act. In fact, what is more difficult is the non-existent single 'cybersecurity law' in Malaysia, rather than the current implementation of 10-related cyber security acts. In this paper, the 10 acts are compiled into a corpus to analyse the language used in these acts via a corpus linguistics approach. A list of frequent words is firstly investigated to see whether the so-called related laws do talk about cybersecurity followed by close inspection of the concordance lines and habitually associated phrases (clusters) to explore use of these words in context. The 'compare 2 wordlist' feature is used to identify similarities or differences between the 10 Malaysian cybersecurity related laws against a corpus of cyber laws from other ASEAN countries. Findings revealed that ASEAN cyber laws refer mostly to three cybersecurity dominant themes identified in the literature: technological solutions, events, and strategies, processes, and methods, whereas Malaysian cybersecurity-related laws revolved around themes like human engagement, and referent objects (of security). Although these so-called cyber related policies and laws in Malaysia are highlighted in the National Cyber Security Agency (NACSA), their practical applications to combat cybercrimes remain uncertain.