• Asian Pacific Journal of Cancer Prevention
• /
• v.13 no.9
• /
• pp.4335-4339
• /
• 2012

Background: Whether sirolimus is useful in the prevention of non-melanoma skin cancer (NMSC) remains unclear and we therefore performed this meta-analysis of randomized controlled trials to test the hypothesis that Sirolimus-based immunosuppression is associated with a decrease in NMSC. Methods: The main outcomes were NMSC, squamous-cell carcinoma and basal-cell carcinoma. The pooled risk ratio (RR) with its 95% confidence interval (95%CI) were used to assess the effects. Results: 5 randomized trials involving a total of 1499 patients receiving kidney transplantation were included. Patients undergoing Sirolimus-based immunosuppression had much lower risk of NMSC (RR = 0.49, 95%CI 0.32-0.76, P = 0.001). Subgroup analyses by tumor type showed that Sirolimus-based immunosuppression significantly decreased risk of both squamous-cell carcinoma (RR = 0.58, 95%CI 0.43-0.78, P < 0.001) and basal-cell carcinoma (RR = 0.56, 95%CI 0.37-0.85, P = 0.006). The quality of evidence was high for NMSC, and moderate for squamous-cell carcinoma and basal-cell carcinoma. No evidence of publication bias was observed. Conclusion: High quality evidence suggests that Sirolimus-based immunosuppression decreases risk of non-melanoma skin cancer, and Sirolimus has an antitumoral effect among kidney-transplant recipients.

• The Bulletin of The Korean Astronomical Society
• /
• v.36 no.2
• /
• pp.101.1-101.1
• /
• 2011

National Meteorological Satellite Center(NMSC) of Korea Meteorological Administration(KMA) is collecting GNSS data in near-real time for about 80 GNSS stations operated by multiple agencies. (eg. National Geographic Information Institute (NGII), Korea Astronomy and Space Science Institute (KASI), DGNSS Central Office) Using these GNSS data, NMSC developed automatic Total Electron Contents(TEC) derivation system over the Korean peninsular every 1-hour based on single station data processing. We present the TEC result and validation of TEC using International GNSS Service(IGS) global TEC data for the case of quiet time and storm time. The future plans for the system improvement will be discussed.

• Korean Journal of Remote Sensing
• /
• v.28 no.1
• /
• pp.101-116
• /
• 2012

In this paper, we have surveyed the existing architectures of the image processing systems for several meteorological satellites and identified issues which are taken into consideration to construct the advanced meteorological satellite image processing system that is being developed by NMSC(National Meteorological Satellite Center). Most of the existing systems provide the functionalities of the image acquisition, the image processing, the data management, and the data dissemination. Those systems have some common problems with respect to system integration and system maintenance. To solve these problems, NOAA, NWS and ESA suggest new system architectures to improve the existing systems. This paper introduces domestic and foreign approaches to build the satellite image processing systems and studies some issues and strategies for developing those systems.

• Archives of Plastic Surgery
• /
• v.44 no.4
• /
• pp.313-318
• /
• 2017

Background Jeju Island is geographically and socioeconomically distinct from the mainland of South Korea. Thus, the presentation and management of non-melanocytic skin cancers (NMSC) of the head and neck may differ from those in other regions of the country. We compared the clinical characteristics and treatment modalities of NMSC on Jeju Island with the findings of similar regional studies. Methods Patient data, including age, sex, diagnosis, tumor site, treatment, and recurrence, were obtained from the medical and pathology records of patients diagnosed with NMSC between January 2010 and June 2015. Results In total, 190 patients (57 men) with a mean age of 75 years (range, 42-97) were assessed. Overall, 203 NMSCs were diagnosed, including 123 basal cell carcinomas and 80 squamous cell carcinomas. The tumor sites included the nose, cheeks, periorbital area, and lips (n=55, 54, 25, and 20, respectively). We identified 92 T1-stage and 60 T2-stage tumors, and 120 cases were treated with wide surgical resection and 17 cases were treated with radiation therapy at the medical center. Of the 120 cases treated surgically, 69 required reconstructive surgery using a local skin flap, 22 required full-thickness skin grafting, and 12 underwent primary closure. Basal and squamous cell carcinomas recurred in 2 and 1 cases, respectively. Conclusions Compared to the reports from other regions, the average patient age was 10 years higher, with a marked female preponderance. While the proportion of squamous cell carcinoma was higher than in other regions, the tumor distribution and surgical management profiles were similar.

• Journal of Satellite, Information and Communications
• /
• v.7 no.3
• /
• pp.30-34
• /
• 2012

National Meteorological Satellite Center(NMSC) of Korea Meteorological Administration(KMA) has launched to implement the application development to get prepared for the space weather operation since 2010. As a action of KMA's space weather work, NMSC constructed Global Navigation Satellite System(GNSS) application system for meteorology and space weather. We will introduce NMSC's space weather application system which derives regional TEC(Total Electron Content) in near real time using nation-wide GNSS network data. First, We constructed system for collecting GNSS data, which is currently collecting about 80 stations operated by agencies like NGII(National Geographic Information Institute), Central Office of DGPS(Differential GPS), and KASI(Korea Astronomy and Space Science) including KMA's own data of 2 stations. In order to retreive regional TEC over Korean peninsular, we build up the automatic processes running every 1-hour. In these processes, firstly, GNSS data of every stations with 24 hours time window are processed to derive DCBs(Differential Code Biases) of each GNSS station and TEC values on every ionosphere piercing point(IPP). Then we made gridded regional TEC map with resolution of 0.25 degree from 31N, 121E to 41N, 135E by combination of all station results within 30 minutes window with assumption that TEC of a given point during a given 30 minutes window would have a constant value. The grid points without TEC value are interpolated using Barnes objective analysis. We presentour regional TEC maps, which can describe better on the status of ionosphere over Korean peninsular compared to IGS TEC maps.

• Archives of Craniofacial Surgery
• /
• v.18 no.1
• /
• pp.37-43
• /
• 2017

Background: Skin cancer is the most common type of cancer. Of the 4 million skin lesions excised annually worldwide, approximately 2 million are considered cancerous. In this study, we aimed to describe a regional experience with skin cancers treated by a single senior surgeon and to provide a treatment algorithm. Methods: The medical records of 176 patients with head and neck non-melanocytic skin cancer (NMSC) who were treated by a single surgeon at our institution between January 2010 and May 2016 were retrospectively reviewed, and their data (age, sex, pathological type, tumor location/size, treatment modality) were analyzed. Patients with cutaneous squamous cell carcinoma (cSCC) who were classified as a high-risk group for nodal metastasis underwent sentinel node mapping according to the National Comprehensive Cancer Network guidelines. Results: Among the patients with NMSC who were treated during this period, basal cell carcinoma (BCC; n=102, 57.9%) was the most common pathological type, followed by cSCC (n=66, 37.5%). Most lesions were treated by complete excision, with tumor-free surgical margins determined via frozen section pathology. Thirty-one patients with high-metastasis-risk cSCC underwent sentinel node mapping, and 17 (54.8%) exhibited radiologically positive sentinel nodes. Although these nodes were pathologically negative for metastasis, 2 patients (6.5%) later developed lymph node metastases. Conclusion: In our experience, BCC treatment should comprise wide excision with tumor-free surgical margins and proper reconstruction. In contrast, patients with cSCC should undergo lymphoscintigraphy, as nodal metastases are a possibility. Proper diagnosis and treatment could reduce the undesirably high morbidity and mortality rates.

• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.7
• /
• pp.3195-3199
• /
• 2016

Background: Skin cancer is a group of heterogeneous malignancies, in general classified into non-melanoma skin cancer (NMSC) and melanoma skin cancer (MSC). Incidences are high in many parts in the world with considerable geographical and racial variation. In the Yemen, there has been scarce information about skin cancer. The aim of this study was to evaluate the demographic characteristics and histological trend of skin cancer in Southern Governorates of Yemen. Materials and Methods: This retrospective study covered 204 cases of skin cancer at the Modern Histopathology Laboratory and Aden Cancer Registry and Research Center, Faculty of Medicine and Health Sciences, University of Aden, for the period 2006-2013. Data were classified regarding different demographic and tumor related variables and analyzed using CanReg-4 for cancer registry and SPSS (version 21). Results: The commonest encountered skin cancer was NMSC (93.1%). Generally, skin cancer appears slightly more frequently in females than males with a 1:1.06 male: female ratio, with a mean age of 62.9 years. Slightly higher than one-third (36.3%) were from Aden governorate. The head and neck proved to be the most common site in both males and females (58%). Basal cell carcinoma (BCC) is the most common histological type of skin cancer (50.5%). Conclusions: Skin cancer is a common cancer in patients living in southern governorates of Yemen. The pattern appears nearly similar to the international figures with a low incidence of MSC.

• Korean Journal of Remote Sensing
• /
• v.36 no.6_1
• /
• pp.1465-1483
• /
• 2020

Evapotranspiration is a concept that includes the evaporation from soil and the transpiration from the plant leaf. It is an essential factor for monitoring water balance, drought, crop growth, and climate change. Actual evapotranspiration (AET) corresponds to the consumption of water from the land surface and the necessary amount of water for the land surface. Because the AET is derived from multiplying the crop coefficient by the reference evapotranspiration (ET0), an accurate calculation of the ET0 is required for the AET. To date, many efforts have been made for gridded ET0 to provide multiple products now. This study presents a comparison between the ET0 products such as FAO56-PM, LDAPS, PKNU-NMSC, and MODIS to find out which one is more suitable for the local-scale hydrological and agricultural applications in Korea, where the heterogeneity of the land surface is critical. In the experiment for the period between 2016 and 2019, the daily and 8-day products were compared with the in-situ observations by KMA. The analyses according to the station, year, month, and time-series showed that the PKNU-NMSC product with a successful optimization for Korea was superior to the others, yielding stable accuracy irrespective of space and time. Also, this paper showed the intrinsic characteristics of the FAO56-PM, LDAPS, and MODIS ET0 products that could be informative for other researchers.

• Korean Journal of Remote Sensing
• /
• v.28 no.1
• /
• pp.79-93
• /
• 2012

This paper suggests a system architecture for the advanced meteorological satellite image processing system that is developing by NMSC(National Meteorological Satellite Center). The meteorology satellite image processing system has basically the image acquisition, the image processing, the data management, and the data dissemination functionalities. However, the existing system has some problems with respect to system integration as well as maintenance to accommodate new satellites and/or the new image processing systems for them which will be developed in the near future. To cope with these problems we propose a new system architecture for the advanced meteorology satellite image processing system. To do this we select as the architectural drivers the quality attributes such as modifiability, inter-operability, extendability, reusability, and platform independency and design the architecture to achieve such quality attributes. We expect that the new approach will solve current issues such as system integration, system dependency, or data management problems and will provide easy ways to incorporate new systems and to maintain them.

• Korean Journal of Remote Sensing
• /
• v.33 no.3
• /
• pp.275-285
• /
• 2017

National Meteorological Satellite Center(NMSC) has produced Sea Surface Temperature (SST) using Communication, Ocean, and Meteorological Satellite(COMS) data since April 2011. In this study, we have developed a new regional COMS SST algorithm optimized within the North-West Pacific Ocean area based on the Multi-Channel SST(MCSST) method and made a composite SST using polar orbit satellites as well as the COMS data. In order to retrieve the optimized SST at Northwest Pacific, we carried out a colocation process of COMS and in-situ buoy data to make coefficients of the MCSST algorithm through the new cloud masking including contaminant pixels and quality control processes of buoy data. And then, we have estimated the composite SST through the optimal interpolation method developed by National Institute of Meteorological Science(NIMS). We used four satellites SST data including COMS, NOAA-18/19(National Oceanic and Atmospheric Administration-18/19), and GCOM-W1(Global Change Observation Mission-Water 1). As a result, the root mean square error ofthe composite SST for the period of July 2012 to June 2013 was $0.95^{\circ}C$ in comparison with in-situ buoy data.