• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.25 no.3
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• pp.254-284
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• 2015

Objectives: There is a requirement to select target materials for mutagenicity(Genotoxicity) testing, so we determined to set the test priorities of them by searching the related database. Methods and Results: We searched a number of databases to find information on mutagenicity tests with chemicals under the Occupational Safety and Health Act(OSH Act), such as KOSHANET, National Toxicology Program(NTP), European Chemicals Agency(ECHA), US National Library of Medicine(NLM), and Genetic Toxicology Data Bank(GENE-TOX), as well as ChemIDplus webpage, and presented the information. Also we anticipated their hazards with ACToR sites to confirm the 58 mutagenicity(Genotoxicity) tests we will perform. Conclusions: We presented target materials for mutagenicity testing with specific GLP tests consisting of reverse mutation(Ames), chromosomal aberration and micronucleus test.

• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.4
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• pp.175-190
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• 2007

Purpose: Ovarian cysts are fluid-filled sacs or pockets within or on the surface of an ovary. Most cysts present little or no discomfort and are noncancerous and harmless. So non-surgical treatments with herbal medicine or acupuncture and moxa therapy are important and suitable in this pathology. But there are few RCT articles about ovarian cyst in Korean Medicine(KM) clinical and research field. Methods: To review treatment method and other research tendency about ovarian cyst in journals related with KM and Traditional Chinese Medicine(TCM) through web-searching. Searching was done through web site #http://omis.ksucc.ac.kr# and pub-med(http://www.ncbi.nlm.nih.gov/sites/entrez) with key words #ovarian cyst#, #TCM#, #herb#, #CAM#, and #acupuncture#. Results: Seven articles were searched in journals related with KM, then six of them were simple case report and the other one was about diagnosis for ovarian cyst and another gynecologic disease such as uterine myoma and infertility through the iris diagnosis. And two articles were searched in journals related with TCM, then one of them was simple case report but the other is RCT article. Conclusion: KM and TCM therapies have some beneficial effect to resolve cyst, but objective power as a evidence is weak in the viewpoint of EBM. So continuous clinical trials such as RCT and multi center trials are needed.

• Journal of Korean Medicine for Obesity Research
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• v.8 no.2
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• pp.1-13
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• 2008

Objective This study was designed to collect latest papers and to find more effective approach for Postmenopausal Women Methods We searched 85 papers in English from Pubmed(www.ncbi.nlm.nih.gov) and selected 40 in favor of our study. In addition to that, we searched 24 papers in Korean from Kiss(www.kiss.kstudy.com) and Medric(www.medric.or.kr). Results are as follows. Results and conclusion Many studies showed that postmenopausal obesity causes cardiovascular disease, osteoporosis, breast cancer and decrease in immunity. To prevent and treat obesity, many studies suggested that dietary and exercise are most effective methods. If needed, medicine and hormone therapy may be recommended as next steps. But, Herb medication and acupuncture are not used yet as postmenopausal obesity treatment around the world. Postmenopausal obesity is significant, resulting in many medical problems. We hope more effective treatment based on these studies and combined with Korean traditional medicine could be developed after.

• Journal of Microbiology and Biotechnology
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• v.18 no.9
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• pp.1492-1495
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• 2008

Successful control of Xanthomonas oryzae pv. oryzicola, the causal agent of bacterial leaf streak, requires a specific and reliable diagnostic tool. A pathovar-specific PCR assay was developed for the rapid and accurate detection ofthe plant pathogenic bacterium Xanthomonas oryzae pv. oryzicola in diseased plant. Based on differences in a membrane fusion protein gene of Xanthomonas oryzae pv. oryzicola and other microorganisms, which was generated from NCBI (http://www.ncbi.nlm.nih.gov/) and CMR (http://cmr.tigr.org/) BLAST searches, one pair of pathovar-specific primers, XOCMF/XOCMR, was synthesized. Primers XOCMF and XOCMR from a membrane fusion protein gene were used to amplity a 488-bp DNA fragment. The PCR product was only produced from 4 isolates of Xanthomonas oryzae pv. oryzicola among 37 isolates of other pathovars and species of Xanthomonas, Pectobacterium, Pseudomonas, Burkholderia, Escherichia coli, and Fusarium oxysporum f.sp. dianthi. The results suggested that the assay detected the pathogen more rapidly and accurately than standard isolation methods.

• The Journal of the Acoustical Society of Korea
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• v.21 no.1
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• pp.37-41
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• 2002

In this paper, we made shorter EDT(early decay time) of room reverberation curve using multiple-channel. The speech signal was processed inverse filtering with full-band and sub-band in the basis MINT, and then the multiple-channel adaptive filters were used LMS (Least Mean Square) and NLMS (Normalized Least Mean Square) algorithm. Experimental results, we could get 1/3 of time reduction at 20dB level in the reverberation curve using full-band NLMS when two microphones were used. Also, it is shown that the speech articulation was improved 80% from the test listeners with the speech, which was to shorten EDT by MINT in the subjective assessments using real room impulse response.

• The Journal of the Acoustical Society of Korea
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• v.18 no.5
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• pp.3-11
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• 1999

The conventional stereophonic acoustic echo cancellers need two adaptive filters to estimate one channel echo signal. Since the two channel signals are strongly correlated, the ESR of the input signals is considerably increased whatever the input signals may be. This causes the slow convergence of the adaptive filter for echo cancellation. To speed up the convergence, the AP algorithm is frequently used for the stereophonic acoustic echo canceller although there isn't a fast version for 2-channel case. The AP algorithm can be approximated with the Gram-Schmidt orthogonalization and a TDL structure. We propose a two channel algorithm for stereophonic acoustic echo canceller with the approximated AP algorithm.

• Clinical and Experimental Reproductive Medicine
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• v.39 no.3
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• pp.95-106
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• 2012

It has been revealed that multiple cohorts of tertiary follicles develop during some animal estrous cycle and the human menstrual cycle. To reach developmental competence, oocytes need the support of somatic cells. During embryogenesis, the primordial germ cells appear, travel to the gonadal rudiments, and form follicles. The female germ cells develop within the somatic cells of the ovary, granulosa cells, and theca cells. How the oocyte and follicle cells support each other has been seriously studied. The latest technologies in genes and proteins and genetic engineering have allowed us to collect a great deal of information about folliculogenesis. For example, a few web pages (http://www.ncbi.nlm. nih.gov; http://mrg.genetics.washington.edu) provide access to databases of genomes, sequences of transcriptomes, and various tools for analyzing and discovering genes important in ovarian development. Formation of the antrum (tertiary follicle) is the final phase of folliculogenesis and the transition from intraovarian to extraovian regulation. This final step coordinates with the hypothalamic-pituitary-ovarian axis. On the other hand, currently, follicle physiology is under intense investigation, as little is known about how to overcome women's ovarian problems or how to develop competent oocytes from in vitro follicle culture or transplantation. In this review, some of the known roles of hormones and some of the genes involved in tertiary follicle growth and the general characteristics of tertiary follicles are summarized. In addition, in vitro culture of tertiary follicles is also discussed as a study model and an assisted reproductive technology model.

• Journal of Korean Medicine for Obesity Research
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• v.7 no.1
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• pp.9-22
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• 2007

Objectives : This study was designed to collect the latest papers and to find more effective approach for childhood obesity. Methods : We searched 107 papers in English from Pubmed(www.ncbi.nlm.nih.gov) and selected 52 in favor of our study. In addition to that, we searched 29 papers in Chinese from www.cnki.net. Results are as follows. Results and Conclusions : There are not completely new treatments for childhood obesity. Instead of that, many studies aimed for prevention through family education, nutrition education, and exercises education. Specially, because some diseases including hypertension, diabetes and heart disease are connected with obese children, medication can be prescribed optionally. In that case, their mental health must be laid emphasis. And in China, TCM(Traditional Chinese Medicine) is very common treatment for childhood obesity. Acupuncture, herb medication and manual therapy could be used usefully. It is suggested that above latest treatments can be combined with Korean traditional treatments method in treating obese children.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.86-86
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• 2017

Prolamins are the main seed storage proteins in cereals. Gluten proteins seem to be prolamins because their primary structure have the meaningful quantity of proline and glutamine amino acid residues. Gluten proteins are found in crops such as wheat (Triticum aestivum), barley (Hordeum vulgare), and rye (Secale cereale) which are major food crops in the Triticeae tribe. Glutenin and gliadin, hordein, and secalin are typical gluten proteins found in wheat, barley, and rye, respectively. Gluten affect grain quality so that many researches, such as isolation or characterization of their genes, have been carried out. To improve the quality of grains in the Triticeae tribe, it is necessary to understand the relationship within their gluten proteins and their evolutionary changes. The sequences of nucleotides and amino acids of gluten protein including glutenins, gliadins, hordeins, and secalins were retrieved from NCBI (https://www.ncbi.nlm.nih.gov/) and Uniprot (http://www.uniprot.org/). The sequence analysis and the phylogenetic analysis of gluten proteins were performed with various website tools. The results demonstrated that gluten proteins were grouped with their homology and were mostly corresponded with the previous reports. However, some genes were moved, duplicated, or disappeared as evolutionary process. The obtained data will encourage the breeding programs of wheat, barley, rye, and other crops in the Triticeae tribe.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 1995.10a
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• pp.185-190
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• 1995

In recent years, many researcher have been interested in the stability of a thin beam. Among them, Pai and Nayfeh[1] had investigated the nonplanar motion of the cantilever beam under lateral base excitation and chaotic motion, but this study is associated with internal resonance, i.e. one to one resonance. Also Cusumano[2] had made an experiment on a thin beam, called Elastica, under bending loads. In this experiment, he had shown that there exists out-of-plane motion, involving the bending and the torsional mode. Pak et al.[3] verified the validity of Cusumano's experimental works theoretically and defined the existence of Non-Local Mode(NLM), which is came out due to the instability of torsional mode and the corresponding aspect of motions by using the Normal Modes. Lee[4] studied on a thin beam under bending loads and investigated the routes to chaos by using forcing amplitude as a control parameter. In this paper, we are interested in the motion of a thin beam under torsional loads. Here the form of force based on the natural forcing function is used. Consequently, it is found that small torsional loads result in instability and in case that the forcing amplitude is increasing gradually, the motion appears in the form of dynamic double potential well, finally leads to complex motion. This phenomenon is investigated through the poincare map and time response. We also check that Harmonic Balance Method(H.B.M.) is a suitable tool to calculate the bifurcated modes.