• New & Renewable Energy
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• v.18 no.4
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• pp.22-37
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• 2022

Large-scale offshore wind power is emerging as a viable solution to achieve carbon neutrality and solve climate change. As power generation complexes require ample space for construction, they create conflicts with residents near the construction site. To resolve the issue with residents, Korea, along with other countries, has developed policies that focus on influencing public perception. However, as the contents of such policies changed several times in a short period in Korea, they were differently applied depending on the timing of the project. This study examines how Korean offshore wind power site development policies, particularly the ones focusing on swaying public perception, were applied differently by regions.

• Journal of Integrative Natural Science
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• v.7 no.4
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• pp.253-259
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• 2014

Protein kinase C theta (PKC-${\theta}$) is a serine/threonine specific protein kinase. It is largely expressed in the T-cells and CD28 signaling. PKC-${\theta}$ phosphorylates diverse proteins that are involved in the various cellular signaling pathways. Activated PKC-${\theta}$ in turn activates other transcription factors that control the proliferation and differentiation of T- cells. PKC-${\theta}$ is considered to be an interesting therapeutic target due to its crucial role in the proliferation, differentiation and survival of T-cells. In the present study, we have performed ligand-based CoMFA study on a series of pyridylpyrazolopyridine derivatives as PKC-${\theta}$ inhibitors. An acceptable CoMFA model ($q^2$=0.544; ONC=4; $r^2$=0.876) was developed and validated by Bootsrapping and progressive sampling. The CoMFA contour map suggested the regions to increase the activity. Bulky substitutions in R2 position of the piperizine ring could increase the activity. Similarly positive, small substitution in the R1 position of the Pyridine ring could considerably increase the activity. Our work could assist in designing more potent PKC-${\theta}$ inhibitors of pyridylpyrazolopyridine derivatives.

• Journal of Integrative Natural Science
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• v.9 no.2
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• pp.113-120
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• 2016

Monopolar spindle 1 (Mps1) is an attractive cancer target due to its high expression levels in a wide range of cancer cells. Mps1 is a dual specificity kinase. It plays an essential role in mitosis. The high expression od Mps1 was observed in various grades of breast cancers. In the current study, we have developed a CoMFA model of pyridazine derivatives as Mps1 kinase inhibitors. The developed CoMFA model ($q^2=0.797$; ONC=6; $r^2=0.992$) exhibited a good predictive ability. The model was then validated by Leave out five, progressive sampling and bootstrapping and found to be robust. The analysis of the CoMFA contour maps depicted favorable and unfavorable regions to enhance the activity. Bulky positive substitution at $R^3$ position and Negative substitution in $R^1$ position is favored could increase the activity. In contrast, bulky substitution in $R^1$ position is not favored. Our results can be used in designing a potent Mps1 (TTK) inhibitor.

• Journal of the Korean association of regional geographers
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• v.22 no.1
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• pp.1-24
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• 2016

This paper is to consider trends and issues of regional research in major sub-fields of human geography in Korea, following the previous one which dealt with contexts and general trends of new regional geography in Korea since the 2000s. They include historical and cultural geography on place and landscape, economic geography on industrial districts or agglomerated regions (i.e. clusters) and urban (and social) geography on urban networks and differentiation. Even though researchers in sub-fields have used different terms and concepts to identify region, they are in common to relate specificities of region to general processes such as (de)modernization, (de)industrialization, and globalization, to understand region as social and discursive constitution as well as substantive reality, and to give more attention to socio-spatial networks and relationality than territoriality of regions. These common points seem to reflect the emerging trend of new regional geography, and to get rid of existing traditional concept of region. It is suggested that major tasks for conceptualization of region in future research are to overcome dichotomy of speciality and generality, of substantive reality and discursive constitution, and of territoriality and relationality, and that important issues for empirical research on region include regional synthesis from new perspectives, uneven regional development as relational process in and between regions, and producing practice for alternative regions.

• Korean Journal of Pharmacognosy
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• v.47 no.2
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• pp.186-191
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• 2016

A new UPLC-DAD method for simultaneous determination of p-coumaric acid and trans-cinnamic acid in propolis was developed using Halo-C18 column and step gradient elution of MeCN and $0.1%H_3PO_4$ in 8 min. The method was validated by specificity, linearity, limit of detection, limit of quantification, precision(intra- and inter-day variability) and recovery tests. The validated method was sufficiently applicable for quantitative analysis of propolis products as well as propolis collected from different regions in Korea. The established method is simple, appropriate and efficient, and can be used for quality assessment of Korean propolis.

• Journal of the Korea Society of Computer and Information
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• v.28 no.1
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• pp.151-159
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• 2023

In the digital age, innovation is at the heart of information technology development. This paper explores the differences of regional innovation capabilities from within the innovation system from a new perspective. By applying the coupling coordination degree model, the coupling coordination degree analysis is conducted for the three systems of innovation (innovation input, innovation output, and innovation environment) in 31 provinces, municipalities, and autonomous regions of China. The results show that: the overall level of coupling coordination degree in China is low, and the number of provinces in good coordination and quality coordination is low number, but they are all distributed in the eastern economically developed regions, showing a high correlation between regional innovation and regional economic development. The overall trend of China's innovation coordination is on the rise. The research results of this paper can provide a new perspective for the evaluation of innovation capability, and also provide an important impact of innovation on promoting the development of ICT industry.

• Journal of the Semiconductor & Display Technology
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• v.7 no.3
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• pp.11-16
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• 2008

The authors investigated an overhead shuttle (OHS) system for automatic transferring the liquid crystal display (LCD) panels. The constructed tracks of OHS system include the linear and curve regions and have been installed on the ceiling to transfer the cassette of LCD glass along the closed-loop and open-loop tracks. In this study, the OHS system was implemented by a proposed linear motor to solve encoder installation and the system cost problems of the long distance transfer system. In addition, we utilized a new algorithm of the position detection and a new control algorithm for driving linear motor. The newly developed control algorithm was demonstrated from both a computer simulation and an experimentation, indicating that the highly reliable and speedy transfer system can enhance the LCD panel productivity of commercial OHS system.

• Journal of Korean Society of Rural Planning
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• v.18 no.3
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• pp.149-164
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• 2012

The purpose of the present study is to construct a rural development strategy from the nexus between spatial changes in specialized crops and suitable cultivation area of the crops. This paper pays particular attention to identify product life cycle of specialized crops in rural areas and estimate the impact of climate change on alterations in spatial distribution of the crops. In order to do so, first of all, this study applies multi-level model (Random coefficient model) to estimate the regional coefficient of five orchard crops. It utilizes the data 1995 to 2010 Korea Agricultural Census. Futhermore, it also adopts overlay analysis by ArcGIS to identify the development path of the crops and the relationship with climate change. Based on the results, it suggests a mechanism activating regional agriculture. The findings propose re-searching and relocating specialized regions of the crops. Especially, it proves each rural area can drive the new agricultural strategy to strengthen regional agriculture by estimating the relationship between development of specialized crops and suitable cultivation areas. For instance, shifting specialized crops in particular regions and enriching genetic or species varieties can be primary measures and it will contribute to improve the reliable base for income sources in the rural communities. This paper also offers specific policy implications regarding rural development plans in response to crops' life cycle and climate changes.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.33 no.3
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• pp.1253-1260
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• 2013

Eco-town development projects have often prevailed throughout the World to initiate the new form of sustainable development plans. As a future development type, the eco-town project shares underlying notions with sustainable development, which has been recently revised into a wider definition; (i) energy efficiency, (ii) climate adaptation, and (iii) socio-economic development. There are four types of eco-town projects based on its characteristics and aims depending on project sites, regions, or countries. This paper tried to demonstrate the types of eco-town projects and summarizes its strategy plans from each type. Many eco-town cases can be placed in one of types, however there cannot be strictly discrete classification by its complicated and composite characteristics of them. In conclusion, the analyzed types can be a useful strategy plan for pursuing further eco-town projects in domestic as well as in international regions.

• Proceedings of the Korean Society of Agricultural Engineers Conference
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• 1998.10a
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• pp.186-191
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• 1998

It is necessary to evaluate the location suitability of protected horticulture facilities to guide and/or to plan new protected horticulture facilities in rural areas. For objective and systematic evaluation of location suitability of protected horticulture, three different evaluation models were constructed based on grading, proportion, and analytic hierarchy process(AHP). The models were used to evaluated the suitability of protected horticulture in three selected regions; suburban, plain, and mountainous. The results showed that there were significant differences in evaluation results of each model among the three regions.