• Transactions of the Korean Society of Mechanical Engineers A
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• v.37 no.6
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• pp.783-790
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• 2013

Circular path generation for ball bar measurement using the simultaneous movement of two axes with at least one rotary axis requires the execution of CAM software. However, a change in the machine type or measurement condition requires a new execution of the CAM software, which is cumbersome. This paper presents a circular path generation technique that does not require CAM software and is applicable to different types of driving axes with an arbitrary structural configuration of machine tools and any ball bar setup condition. Mathematical equations are derived for three cases using the proposed technique. In addition, to inspect the measurement feasibility for avoiding physical interference among the ball bar parts, a tilting angle calculation is proposed. The validity of the proposed technique was verified by performing a ball bar experiment with A and C as the simultaneous axes of a five-axis machine tool.

• Journal of Advanced Navigation Technology
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• v.19 no.4
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• pp.338-344
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• 2015

The national competency standards (NCS) is a systematize and standardize for skills required to perform their job. The NCS has developed a learning module with materialization and standardize by competence unit element, which is the unit of specific job competency. The existing curriculum is material to gab analysis for use in education training with competence unit element. The existing gab analysis has evaluated subjectively by experts. The gab analysis by experts bring up a subject subjective decision, accuracy lack, temporal and spatial inefficiency by psychological factor. This paper is proposed automated evaluation model for problem resolve of subjective evaluation. This paper use index term extraction, term frequency-inverse document frequency for feature value extraction, cosine similarity algorithm for gab analysis between existing curriculum and competence unit element. This paper was presented similarity mapping table between existing curriculum and competence unit element. The evaluation model in this paper should be complemented by an improved algorithm from the structural characteristics and speed.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.16 no.4
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• pp.127-134
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• 2017

A rotary table is a positioning device used in metalworking for the multiple axes of machine tools, and the utilization trend is increasing with machining efficiency. In the construction of a rotary table, the core technology is a power transfer unit that drives the table, typically a gear type and a roller gear cam type. As the rollers installed on the turret column have rolling movement on the contact surface of the roller gear cam, the roller gear cam type has the advantage of low wear, high load, and fast driving. Therefore, it is currently being replaced by a roller gear cam type. In this study, we researched a 5-axis machining method for the roller gear cam on a rotary table and a new method of applying double roller gear cam curve to reduce the noise and shock between the roller and the cam surface. We implemented the 5-axis machining process in this study using software to generate NC-code and machined the roller gear cams using a Mazak Integrex-200IV. We found that the roller gear cam and turret were able to identify mutual touch status and the noise from the operation of the roller gear cam was substantially reduced.

• Biomolecules & Therapeutics
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• v.19 no.1
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• pp.126-133
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• 2011

The fruit of Actinidia arguta (AA) has been used mainly for the treatment of skin diseases, diuresis, diabetes mellitus and osteoporosis in Korean traditional medicine. It is known that AA (hardy kiwi) fruit extract has an effect on 2-chloro-1,3,5-trinitrobenzene-induced atopic dermatitis-like skin lesions in NC/Nga mice. Mode of action for it is associated with the modulation of biphasic Th1/Th2 cytokines. Furthermore, DA9102 containing AA is a herbal medicine currently under phase II clinical trial for atopic dermatitis in Korea. However, no active principles of AA on the decrease of Th2 cytokines including IL-4 and IL-10 have been identified. In this study, bioactivity-guided fractionation of an alcohol extract from the dried fruits of AA using ELISA assay for IL-4 production led to the isolation of $\alpha$-linolenic acid (I), linoleic acid (II), ethyl linolenate (III), ethyl linoleate (IV) and ethyl stearate (V) as the major active components. These compounds showed the down-regulatory effects of IL-4 production in A23187-stimulated RBL-2H3 cells without cytotoxicity.

• Journal of Applied Biological Chemistry
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• v.54 no.3
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• pp.197-205
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• 2011

This study was carried out to investigate the dietary effects of Monascus pilosus mycelial extract on obesity in high-fat with cholesterol-induced obese rat models. It was observed that M. pilosus mycelial extract contains $25.85{\pm}1.98mg%$ of total monacolin K without citrinin by highperformance liquid chromatography (HPLC). The rats were randomly divided into 2 groups; normal control and a high-fat with cholesterol diet group. The high-fat with cholesterol diet group was fed a 5L79 diet with an added 15% lard and 1% cholesterol supplemented diet for 3 weeks for induction of obesity. After induction, obesity was confirmed by checking obesity indexes, the animals were divided into 4 groups (n=5); first, the normal control (NC), and then taken from the obese model of rats, a high-fat with cholesterol diet obesity control group (HF), 0.5% M. pilosus mycelial extract supplemented high-fat with cholesterol diet group (MPMs), 2% conjugated linoleic acid supplemented high-fat with cholesterol diet group (CLA) for 7 weeks. Body weight gains, obesity indexes, and body fat contents in the experimental groups (MPMs and CLA) were decreased compared with HF group. Feed Efficiency Ratio (FER) in MPMs was significantly lower than that of HF without change of feed intake. These results suggested that the anti-obesity effects of the M. pilosus mycelial extracts (MPMs) could prevent obesity induced by high-fat with cholesterol diet possibly via inhibition of lipid absorption.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.2
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• pp.753-759
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• 2014

This study aim to arrange ISD from the competency context and from the Dual major base of junior colleges related to Dept. of Administrative Professional. By analysing the curricula of the Korean capital area junior colleges of secretarial service, extracted some ability factor and classified it on the basis of NCS and competency grouping. From this, the basic direction of Standardizing Competency can be determined and it applied to develop ISD. Thus the Multi ground base of ISD can be constructed which served on developing a convergence human resource. It may give an implication and practical methodology for the junior colleges of secretarial service related Dept. to make a framework for developing a multi ground based ISD which can be designed from the multiple competency and from more than two complex major.

• Korean Journal of Veterinary Service
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• v.43 no.2
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• pp.45-52
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• 2020

A grading system is implemented to evaluate the meat quality of Hanwoo. In the grading system, grade 1++A is the highest grade. Livestock farms breed Hanwoo with good quality feed in order to obtain the highest grade. In this process, the content ratios of muscles in individual regions can be changed. To find out the muscle distribution ratios of Hanwoo steers, grade 1A, 1+A, and 1++A Hanwoo steers were compared with grade 1+A Hanwoo female. Grade 1A Hanwoo steers had higher ratios of shank (SK), brisket and flank (BF), neck chain (NC), and inside skirt (IS) meats and a lower ratio of striploin (SL) meat compared to grade 1+A Hanwoo feamle. Grade 1++A Hanwoo steers had higher ratios of neck (NK) and loin (LN) meats and lower ratios of inside skirt (IS), tenderloin (TL), top round (TR), eye round (ER), bottom round (BR), bottom sirloin triangle (BST), and knuckle (K) meats compared to grade 1+A Hanwoo steers. In comparison between grade 1A and 1++A Hanwoo steers, the ratio of shank (SK) was significantly lower in higher quality meats. If the changes are continuously studied to improve the process so that the ratios of partial meats of the regions highly preferred by consumers can increase, it will contribute to increases in the incomes of livestock farms and enable Hanwoo to grow into a global brand.

• Journal of Convergence for Information Technology
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• v.9 no.3
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• pp.82-89
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• 2019

The reason why NCS education is conducted in college is because students are expected to improve their skills through practical education. In addition, NCS education is expected to have a positive impact on job competence and competitiveness. The purpose of this study is to explain the necessity of NCS education, and to analyze whether the education transition and practical performance are manifested. For this purpose, the research model was composed of "NCS Education ${\Rightarrow}$ Educational Transition ${\Rightarrow}$ Practical Results" and surveyed about 300 college students in the metropolitan area. If NCS education is necessary in practice, colleges and other educational institutions should plan to make NCS education operate efficiently. As a analysis result, it was confirmed that the internal consistency was secured and both the intensive validity & discriminant validity were confirmed in the validity. As a result of using the structural equation model, this research model was found to be suitable. As a result of the hypothesis test, it is analyzed that the standardization coefficient of the research hypothesis is above the appropriate level and the correlation is highly formed.

• The Korean Journal of Physiology and Pharmacology
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• v.26 no.1
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• pp.37-45
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• 2022

The aim of the present study was to investigate the physiological role of nicotinamide phosphoribosyltransferase (NAMPT) associated with odontogenic differentiation during tooth development in mice. Mouse dental papilla cell-23 (MDPC-23) cells cultured in differentiation media were stimulated with the specific NAMPT inhibitor, FK866, and Visfatin (NAMPT) for up to 10 days. The cells were evaluated after 0, 4, 7, and 10 days. Cell viability was measured using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. The mineralization assay was performed by staining MDPC-23 cells with Alizarin Red S solution. After cultivation, MDPC-23 cells were harvested for quantitative PCR or Western blotting. Analysis of variance was performed using StatView 5.0 software (SAS Institute Inc., Cary, NC, USA). Statistical significance was set at p < 0.05. The expression of NAMPT increased during the differentiation of murine odontoblast-like MDPC-23 cells. Furthermore, the up-regulation of NAMPT promoted odontogenic differentiation and accelerated mineralization through an increase in representative odontoblastic biomarkers, such as dentin sialophosphoprotein, dentin matrix protein-1, and alkaline phosphatase in MDPC-23 cells. However, treatment of the cells with the NAMPT inhibitor, FK866, attenuated odontogenic differentiation, as evidenced by the suppression of odontoblastic biomarkers. These data indicate that NAMPT regulated odontoblastic differentiation through the regulation of odontoblastic biomarkers. The increase in NAMPT expression in odontoblasts was closely related to the formation of the extracellular matrix and dentin via the Runx signaling pathway. Therefore, these data suggest that NAMPT is a critical regulator of odontoblast differentiation during tooth development.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.6 no.10
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• pp.145-153
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• 2016

The purpose of the study is to draw competencies of faculty members at graduate school faculty to implements the NCS-based curriculum. A set of competency was deductively derived from a total of three professors and consultants with more than ten-year experiences and has been involved in developing the college curriculum. The political endeavors of the Korean government toward the competency-based education have been implemented as a movement to the NCS-based curriculum. The requirements for the reorganization of curriculum and education system as well as cooperation among faculty, industry, region and development part of NCS were suggested for the activation of NCS based education and the operation of NCS. However, one of the most critical factors in introducing and implementing the NCS-based curriculum is the role of faculty members. Therefore, it is an urgent issue to equip the faculties with required competencies. Result showed that the competencies required professors at graduate school for the NCS-based curriculum implementation were classified into four areas: marco-level curriculum development; micro-level course design; knowledge across areas; and attitude across areas.