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Effect of Fingertip Temperature on Multi-finger Actions in Young Adults (손 끝 온도변화가 젊은 성인의 다중 손가락 동작에 미치는 효과)

  • Shin, Narae;Xu, Dayuan;Song, Jun Kyung;Park, Jaebum
    • Korean Journal of Applied Biomechanics
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    • v.29 no.3
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    • pp.157-166
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    • 2019
  • Objective: This study examined the effects of stimulating fingertip temperature on the patterns of force sharing and stability properties during multi-finger force production tasks. Method: 9 adult subjects (male: 3, female: 6, age: $26.11{\pm}4.01yrs$, height: $169.22{\pm}5.97cm$, weight: $61.44{\pm}11.27kg$) participated in this study. The experiment consisted of three blocks: 1) maximal voluntary contraction (MVC) task, 2) single-finger ramp task to quantify enslaving (i.e., unintended force production by non-task fingers), and 3) 12 trials of multi-finger steady-state force production task at 20% MVC. There were three temperature conditions including body-temperature (i.e., control condition), $40^{\circ}C$, and $43^{\circ}C$, and the stimulation was given to the index finger only for all experimental conditions. Results: There were no significant differences in the MVC forces, enslaving, and the accuracy of performance during the steady-state task between the conditions. However, the share of stimulated index finger force increased with the index fingertip temperature, while the share of middle finger force decreased. Also, the coefficient of variation of both index and middle finger forces over repetitive trials increased with the index fingertip temperature. Under the framework of the uncontrolled manifold (UCM) hypothesis used to quantify indices of multi-finger synergies (i.e., stability property) stabilizing total force during the steady-state task, the two variance components within the UCM analysis increased together with the fingertip temperature, while no changes in the synergy indices between the conditions. Conclusion: The current results showed that fingertip temperature stimulation only to index finger does not affect to muscle force production capability of multi-finger, independence of individual fingers, and force production accuracy by the involvement of all four fingers. The effect of fingertip temperature on the sharing pattern and force variation may be due to diffuse reflex effects of the induced afferent activity on alpha-motoneuronal pools. However, the unchanged stability properties may be the reflection of the active error compensation strategies by non-stimulated finger actions.

Evaluation of Toxicity of Heavy Metals and Surfactants Using Vibrio Fischeri and Daphnia Magna (발광박테리아(Vibrio fischeri)와 물벼룩(Daphnia magna)을 이용한 중금속 및 계면활성제의 혼합독성 평가)

  • Paik, Dohyeon;Lee, Narae;Lee, Sangmin;Hong, Sungchul
    • Journal of the Korean Society of Urban Environment
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    • v.18 no.4
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    • pp.429-437
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    • 2018
  • In this study, the mixed toxicity of heavy metals (Cu, Pb, Hg) and surfactants (SLS, ALS) was evaluated by using Vibrio fischeri and Daphnia magna. The sensitivity of ecotoxicity to heavy metals was sensitive to daphnia but the case of surfactants were more sensitive to Vibrio fischeri. Experimental results of Vibrio fischeri show that the toxicity value P(O) was lower than the predicted value P(E), and the antagonistic effect was observed when the heavy metal and the surfactant were mixed. It seems that SLS and ALS, which are anionic surfactants, have anionic form on the hydrophilic head, so that they have an antagonistic effect that they are bonded with heavy metal ion which is a cation type and the actual toxicity is lowered. In Daphnia magna, the results showed that antagonistic, additive and synergistic effects were in order as concentrations increased. As the concentration increases, Daphnia magna, which is highly sensitive to heavy metals, seems to have a synergistic effect with a rapid increase in mortality.

A Study of the Reliability and Validity of the Korean Version of DSM-5 Symptom Measure-Inattention and Anger for Parent and Guardian of Child Age 6 to 17

  • Shin, Min-Sup;Kim, Bung-Nyun;Cho, Minji;Jang, Mirae;Shin, Hanbyul;Do, Ryemi;Park, Hyungseo;Yoon, Narae;Noh, Gahye;Song, Jae-Won;Ahn, Yebin;Shin, Jiyoon;Jang, Soomin;Noh, Eunjung;Lee, Eunhwa
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.32 no.2
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    • pp.71-78
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    • 2021
  • Objectives: This study was conducted to investigate the reliability and validity of the Korean version of the DSM-5 Level 2 Cross-Cutting Symptom Measure-inattention [Swanson, Nolan and Pelham, version IV (SNAP-IV)] and anger [Patient-Reported Outcome Measurement Information System (PROMIS) Anger] for parents and guardians of children aged 6-17 years. Methods: We included 104 children and adolescents diagnosed with attention-deficit/hyperactivity disorder (ADHD), ADHD with anxiety and depression, depressive disorder, anxiety disorder, and tic disorder with somatic symptoms (ADHD=41, depression=9, anxiety=14, ADHD+anxious depression=11, tic+somatic symptoms=29). Their ages ranged from 8 years to 15 years. The participants' mothers completed the SNAP-IV, PROMIS Anger scale, Korean version of the IOWA Conners Rating Scale (K-IOWA), and Korean ADHD Rating Scale (K-ARS) so that the reliability and validity of the SNAP-IV and PROMIS Anger scales, which are DSM-5 scales for assessing inattention and anger of children and adolescents, could be examined. Results: The reliability coefficient of SNAP-IV (Cronbach's α) was 0.94. The correlation coefficients between SNAP-IV, K-IOWA inattention, and K-ARS inattention scores ranged from 0.73 to 0.86. The mean SNAP-IV scores of the ADHD and the ADHD+anxious depression groups were significantly higher than those of the anxiety and the tic+somatic symptoms groups. The reliability coefficient of the PROMIS Anger was 0.91. The correlation coefficient between PROMIS Anger and K-IOWA oppositional/defiant scores was 0.75. The PROMIS Anger mean score of the ADHD+anxious depression group tended to be higher than that of the other groups. Conclusion: These results suggest that the Korean version of the DSM-5 Level 2 Cross-Cutting Symptom Measure-inattention and anger for parent and guardian of child age 6-17 might be a reliable and valid test and may be useful for screening children and adolescents with ADHD.

Error analysis of areal mean precipitation estimation using ground gauge precipitation and interpolation method (지점 강수량과 내삽기법을 이용한 면적평균 강수량 산정의 오차 분석)

  • Hwang, Seokhwan;Kang, Narae;Yoon, Jung Soo
    • Journal of Korea Water Resources Association
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    • v.55 no.12
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    • pp.1053-1064
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    • 2022
  • The Thiessen method, which is the current area average precipitation method, has serious structural limitations in accurately calculating the average precipitation in the watershed. In addition to the observation accuracy of the precipitation meter, errors may occur in the area average precipitation calculation depending on the arrangement of the precipitation meter and the direction of the heavy rain. When the watershed is small and the station density is sparse, in both simulation and observation history, the Thiessen method showed a peculiar tendency that the average precipitation in the watershed continues to increase and decrease rapidly for 10 minutes before and after the peak. And the average precipitation in the Thiessen basin was different from the rainfall radar at the peak time. In the case where the watershed is small but the station density is relatively high, overall, the Thiessen method did not show a trend of sawtooth-shaped over-peak, and the time-dependent fluctuations were similar. However, there was a continuous time lag of about 10 minutes between the rainfall radar observations and the ground precipitation meter observations and the average precipitation in the basin. As a result of examining the ground correction effect of the rainfall radar watershed average precipitation, the correlation between the area average precipitation after correction is rather low compared to the area average precipitation before correction, indicating that the correction effect of the current rainfall radar ground correction algorithm is not high.

A study on spatial error occurrence characteristics of precipitation estimation of rainfall radar (강우레이더 강수량 관측의 공간적 오차 발생 특성 연구)

  • Hwang, Seokhwana;Yoon, Jung Soo;Kang, Narae
    • Journal of Korea Water Resources Association
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    • v.55 no.12
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    • pp.1105-1114
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    • 2022
  • A study on a method to overcome the limitations of the topographical and hydrological observation environment for estimating the QPE with high consistency with the ground rainfall by utilizing the spatiotemporal observation advantages of the rainfall radar for use in flood forecasting, and quantitative observations of localized rainfall due to these limiting conditions Uncertainty should be identified in terms of flood analysis. Against this background, in this study, 22 major heavy rain events in 2016 were analyzed for each of Mt. Biseul (BSL), Mt. Sobaek (SBS), Mt. Gari (GRS), Mt. Mohu (MHS), and Mt. Seodae (SDS) to determine the observation distance and altitude. The uncertainty of observation was quantified and an error map was derived. As a result of the analysis, it was found that, on average, the rainfall radar exceeded 10% up to 100 km and 30% over 150 km. Based on the average radar operating altitude angle, it was found that the error for the altitude was approximately 10% or less up to the second altitude angle, 20% at the third or higher altitude angle, and more than 50% at the fourth altitude angle or higher.

Student Engagement in Student Support System Reform: A Case Study (학생지원체계 개선을 위한 학생주도 교육평가 사례)

  • Yena Jang;Seo Yoon Kim;Ji Yoon Kang;Donghwa Kang;Na Hyeon Kweon;Ga Yeon Kim;Narae Kim;Sang Hun Kim;Seongwoo Kim;Juhee Kim;Chae Yeon Kim;Shinyoung Park;Ju Yeon Park;Ji Su Park;Geon Ho Lee;Bora Im;Bo Young Yoon
    • Korean Medical Education Review
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    • v.25 no.2
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    • pp.174-183
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    • 2023
  • Educational evaluation involves data collection and the analysis of various education-related factors to make decisions that improve educational quality. Systematic educational evaluation is essential for enhancing the quality of education. This study reports a case of student-conducted process evaluation of a medical school's student support system and the procedure for devising improvement plans. Sixteen Inje University College of Medicine students participated in the Education Evaluation Committee (IUCM-EEC) to understand the educational improvement process as learners and actively achieve improvement. The Quality Improvement Committee of the Inje University College of Medicine (IUCM-QIC) decided to reform its student support system based on a previous educational evaluation in 2019. The evaluation of the student support system was conducted for 10 months in 2021 by the student subcommittee, under the guidance of the IUCM-EEC. The CIPP (context-input-process-product) evaluation model was used for a systematic evaluation. Accordingly, the subcommittee developed evaluation criteria and indicators, and analyzed relevant data collected from surveys and the previous literature. For further recommendations and revision ideas, the student subcommittee members interviewed faculty members from six other medical schools and also conducted a focus group interview with the dean and vice deans of IUCM. Finally, the student subcommittee submitted a report to the IUCM-QIC. Communication with various stakeholders is essential for a successful evaluation process. In this case, students, as key stakeholders in education, evaluated the student support system. Their active participation helped improve their understanding of the evaluation process.

Anti-Inflammatory and Enzyme Inhibitory Activities of Polyphenols from Peanut (Arachis hypogaea L.) Hull

  • Mihyang Kim;Yeo Ul Cho;Narae Han;Jin Young Lee;Yu-Young Lee;Moon Seok Kang;Hyun-Joo Kim
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2022.10a
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    • pp.312-312
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    • 2022
  • Peanut hull as by-product has been discarded during peanut processing. However, peanut hull contains plenty of polyphenols that shows various physiological activities. The objectives of this study were to investigate anti-inflammatory and enzyme inhibitory activities of polyphenols from 'Sinpalkwang' peanut (Arachis hypogaea L.) hull. Compounds were isolated from methanol extracts of peanut hull by preparative-high performance liquid chromatography after identifying and quantifying polyphenols using Ultra performance liquid chromatography (UPLC) and UPLC-Quadrupole time-of-flight-mass spectrometry profiling. The structures of compounds were elucidated by one-dimensional [1H, 13C] nuclear magnetic resonance (NMR) and two-dimensional NMR (correlated spectroscopy, heteronuclear single quantum coherence and heteronuclear multiple bond correlation). Three compounds were identified as 5,7-dihydroxy-4H-chromen-4-one (peak 2), luteolin (peak 4) and eriodictyol (peak 5). Significant differences in inflammatory mediator such as nitric oxide (NO), interleukin-6 (IL-6) and interleukin-1β (IL-lβ) in lipopolysaccharide stimulated Raw 264.7 macrophages and in enzyme (xanthine oxidase [XO] and α-glucosidase [AG]) inhibitory activities were observed between three compounds (p < 0.05). Peak 5 treated Raw 264.7 macrophages showed lower content of NO (16.4 uM), IL-6 (7.0 ng/mL), and IL-1β (60.6 pg/mL) than peak 2 (NO: 28.3 uM, IL-6: 11.3 ng/mL, IL-1β: 66.9 pg/mL) and peak 4 (NO: 24.7 uM, IL-6: 9.3 ng/mL, IL-1β: 62.6 pg/mL). Peak 5 showed higher XO inhibitory activity (84.7%) and higher AG inhibitory activity (52.4%) than peak 2 (XO inhibitory activity: 45.4%, AG inhibitory activity: 21.6%) and peak 4 (XO inhibitory activity: 37.9%, AG inhibitory activity: 37.5%) at concentration of 0.5mg/mL. This study suggests that peanut hull could be a potential source of anti-inflammatory and physiological materials while creating new use of discarded peanut hull as by-products concomitantly.

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Basic Properties and Solution Behavior of New Naturally Derived Cosmetic Preservative, and Stability of Cosmetic Formulation (신규 화장품용 천연유래 보존제의 물성 측정, 용액 거동 및 보존제 포함 화장품의 제형 안정성)

  • Subin Shin;Jeongeun Park;Nayeon Ko;Mijung Kim;Hyewon Shin;Dasom Lee;Narae Kim;Taeshik Earmme;Gugin Jeong;Joonwon Bae
    • Applied Chemistry for Engineering
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    • v.35 no.2
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    • pp.122-127
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    • 2024
  • Cosmetic preservatives are an important class of ingredients in terms of ensuring sustainable use and providing customer satisfaction. Recently, a great deal of interest has been drawn to the production and use of toxic-free, naturally derived preservatives. In this work, a new naturally derived preservative (laurimino bispropanediol, LB) was developed to replace the most widely used diol preservatives, such as 1,2-hexanediol or 1,2-octanediol. The basic properties of the obtained preservative were measured, and the solution behavior of the preservative in an aqueous medium was examined. The feasibility of micelle formation in the preservative solution was investigated using the fluorescence (FL) based pyrene method. Micelle formation was feasible owing to the relatively long hydrophobic chains and increased hydroxyl groups in the preservative molecules. The emulsification capability of the preservative was assessed using the Rosano and Kimura method, showing that the preservative possessed emulsifying capability in an organic solvent (benzene) and soy bean oil. In addition, the dispersion stability of cosmetic formulations, including the new LB preservatives such as essence and lotion, was demonstrated by comparing the light transmittance of the formulations. This article provides important information for future research regarding the synthesis and practical applications of new toxic-free naturally derived preservatives.

Floristic study of Sonjukdo Island(Yeosu-si), Korea (손죽도(여수시)의 관속식물상)

  • Jung-Hyun Kim;Seog Woo Kwon;Sung-Ae Park;Narae Yun;Bo-Mi Nam
    • Korean Journal of Environmental Biology
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    • v.42 no.1
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    • pp.28-45
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    • 2024
  • This study was conducted to investigate the flora of Sonjukdo Island(Yeosu-si), Korea. From results of four field surveys from April 2023 to October 2023, we identified 483 total taxa, representing 440 species, seven subspecies, 35 varieties, and one hybrid. They were placed in 322 genera and 109 families, including 249 taxa newly recorded in this study. Among them, four taxa were endemic to Korea, four taxa were IUCN red list plants, and 22 taxa were climate sensitive indicator plants. Floristic target plants amounted to 99 taxa, including two taxa of grade IV, 41 taxa of grade III, 10 taxa of grade II, and 46 taxa of grade I. A total of 54 taxa of alien plants were identified, with a Naturalized Index of 11.2% and an Urbanization Index of 13.8%. Three plants disturbed the ecosystem. The flora of this surveyed area belongs to the south-coast province among floral provinces of the Korean Peninsula. Our results provide basic data on vascular plants flora, plant species diversity, and distributional changes.

Utilizing deep learning algorithm and high-resolution precipitation product to predict water level variability (고해상도 강우자료와 딥러닝 알고리즘을 활용한 수위 변동성 예측)

  • Han, Heechan;Kang, Narae;Yoon, Jungsoo;Hwang, Seokhwan
    • Journal of Korea Water Resources Association
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    • v.57 no.7
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    • pp.471-479
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    • 2024
  • Flood damage is becoming more serious due to the heavy rainfall caused by climate change. Physically based hydrological models have been utilized to predict stream water level variability and provide flood forecasting. Recently, hydrological simulations using machine learning and deep learning algorithms based on nonlinear relationships between hydrological data have been getting attention. In this study, the Long Short-Term Memory (LSTM) algorithm is used to predict the water level of the Seomjin River watershed. In addition, Climate Prediction Center morphing method (CMORPH)-based gridded precipitation data is applied as input data for the algorithm to overcome for the limitations of ground data. The water level prediction results of the LSTM algorithm coupling with the CMORPH data showed that the mean CC was 0.98, RMSE was 0.07 m, and NSE was 0.97. It is expected that deep learning and remote data can be used together to overcome for the shortcomings of ground observation data and to obtain reliable prediction results.