• The Korean Journal of Pharmacology
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• v.30 no.2
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• pp.167-179
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• 1994

Recent evidence indicates that glial cells have a wide range of funtions which are critical for maintaining a balanced homeostatic environment in the central nervous system(CNS) peripheral nervous system(PNS). Morever, astrocytes are known to participate in the tissue repair and neuroimmunologic events within the CNS through many kinds of growth factors and cytokines. We investigated the effect of $TGF\;{\beta}_1$, on the growth and biochemical changes of rat glial cells in culture. The proliferative effect was determined by $^3H-thymidine$ uptake and the double immunostain with anti-cell-specific marker and anti-Bromodeoxyuridine(BrdU) antibody. To check the effect of biochemical changes we compared the amounts of glial fibrillar acidic protein(GFAP) and the activity of glutamine synthetase(GS) in astrocyte. And the amounts of myelin basic protein and the activity of 2',3'-cyclic nucleotide phosphohydrolase(CNPase) were measured in oligodendrocyte and the amounts of peripheral myelin in Schwann cell. When $TGF\;{\beta}_1$, was treated for 2 days with cultured glial cell, $TGF\;{\beta}_1$, decreased the $^3H-thymidine$ uptake and proliferation index of double immunostain of astrocytes, which indicates the inhibition of astroglial DNA synthesis, but stimulated the growth of Schwann cell. Also, $TGF\;{\beta}_1$, decrease the GS activity and increased the amounts of GFAP in astrocyte. In the case of Schwann cells the amounts of peripheral myelin was increased when treated with $TGF\;{\beta}_1$. However, $TGF\;{\beta}_1$, didn't show any effect on the proliferation and biochemical changes in oligodendrocyte. These results suggest that $TGF\;{\beta}_1$, might have a critical action in the regulation of proliferation and biochemical changes in glial cells, especially astrocyte.

• Journal of Environmental Science International
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• v.16 no.8
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• pp.921-928
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• 2007

The objective of this work is the air quality modeling according to the scenarios of emission on complex terrain. The prognostic meteorological fields and air quality field over complex areas of Seoul, Korea are generated by the PSU/NCAR mesoscale model (MM5) and the Third Generation Community Multi-scale Air Quality Modeling System (Models - 3/CMAQ), respectively. The emission source was driven from the Clean Air Policy Support System of the Korea National institute of Environmental Research (CAPSS), which is a 1 km x 1 km grid in South Korea during 2003. In comparison of air quality fields, the simulated averaged $PM_{10},\;NO_2,\;and\;O_3$ concentration on complex terrain in control case were decreased as compared with base case. Particularly $PM_{10}$ revealed most substantial localized differences by $(18{\sim}24{\mu}g/m^3)$. The reduction rate of $PM_{10},\;NO_2,\;and\;O_3$ is respectively 18.88, 13.34 and 4.17%.

• School Mathematics
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• v.13 no.2
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• pp.323-343
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• 2011

The study of 2011 education course revision proposal suggests that middle school level function shall be taught with emphasis on its role as tool to understand the situations of actual world, and the concept shall be extended in high school into formularized setting that integrate various fields based on middle school function. In revising education course, the circumstances of other countries are desired to be considered to keep abreast of international standard education courses. In this study, the textbooks of Gesamtschule a general school a school type similar to the education system in Korea among various school forms of Germany were selected to look into the characteristics of function introduction and teaching & learning in Germany, and the textbooks were compared and analyzed with those of Korea. As a result of comparison and analysis on the system and contents with emphasis on function area, German textbooks differed from the 7th revised education course on the introduction of function concept, contents development method and method of instructing on graph etc. Such differences are anticipated to serve as data for reference in the development of revised education courses and textbooks in Korea.

• Smart Structures and Systems
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• v.16 no.2
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• pp.243-262
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• 2015

Optimal sensor placement (OSP) is a critical issue in construction and implementation of a sophisticated structural health monitoring (SHM) system. The uncertainties in the identified structural parameters based on the measured data may dramatically reduce the reliability of the condition evaluation results. In this paper, the information entropy, which provides an uncertainty metric for the identified structural parameters, is adopted as the performance measure for a sensor configuration, and the OSP problem is formulated as the multi-objective optimization problem of extracting the Pareto optimal sensor configurations that simultaneously minimize the appropriately defined information entropy indices. The nondirective movement glowworm swarm optimization (NMGSO) algorithm (based on the basic glowworm swarm optimization (GSO) algorithm) is proposed for identifying the effective Pareto optimal sensor configurations. The one-dimensional binary coding system is introduced to code the glowworms instead of the real vector coding method. The Hamming distance is employed to describe the divergence of different glowworms. The luciferin level of the glowworm is defined as a function of the rank value (RV) and the crowding distance (CD), which are deduced by non-dominated sorting. In addition, nondirective movement is developed to relocate the glowworms. A numerical simulation of a long-span suspension bridge is performed to demonstrate the effectiveness of the NMGSO algorithm. The results indicate that the NMGSO algorithm is capable of capturing the Pareto optimal sensor configurations with high accuracy and efficiency.

• International Journal of Human Ecology
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• v.8 no.1
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• pp.53-66
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• 2007

The purpose of the study is to microscopically re-clarify the reality of renovation and conflicts that females faced within their families since the modernization period. The research method is the literature review. Families have been considered based on the formation of individual spaces for housing by husband and wife. The study will analyze changes in daily lives and housing consciousness to understand how such housing areas are transforming. The results of the study are as follows. From the perspective of symbolic interaction, in a traditional society, Korean females have been experiencing alienation and isolation in private areas in their daily lives due to family centrism and male chauvinism. Since industrialization, the female's role as the major consumer has been emphasized. Also, in terms of housing space, the symbol of family interaction was influenced more by utility, rationality, and equality than spatial hierarchy. From the perspective of the dailiness of phenomenological traditions, the modern girl's housing consciousness, which appeared during modernization under colonial rule, is considered as revolutionary from traditional society. Soon after in industrialized society, females appeared as leaders of 'sweet home'. They also became the main body to create the space for living by giving meaning to the interior of housing. Considering dailiness from the Marxist perspective, under the colonial social system, females became the subject of colonization through education, socialization, and the labor market. The modern public system presents the female as 'a wise mom and good wife' or laborer causing the colonization of her life. After industrialization, the socialization of housing and prioritization of spending caused the daily lives of females to become colonized by the consumption market.

• Journal of Environmental Science International
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• v.12 no.2
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• pp.207-215
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• 2003

The purpose of this study is to estimate the air quality of subway stations having underground platforms in Busan Metropolitan City, from September to November 2000, over seven times. The places of the investigation include Yonsan-dong station, Somyon station, Busan station, Nampo-dong station, and Dusil station. Samplings were conducted at three points in each station, i.e. gates, ticket gates, and platforms. CO, NO, $NO_2$, and $O_3$ were the main components of air for this analysis. In order to more fully understand station environments, we also measured an air temperature at each point. The results showed that the $O_3$ average concentration of Yonsan-dong station was higher than others with 38~51 ppb. The average concentration of NO was high at the ticket gate and platform at Somyon station (119 ppb, 122 ppb) and Nampo-dong station (102 ppb, 100 ppb). These results show that the air pollution of stations with underground shopping malls were higher than others. At Somyon station having a junction station, NO and $NO_2$ concentration levels of platform-2 (noncrowded) were higher than platform-1 (crowded). This is most likely due to the accumulation of air pollutants and inadequate ventilation systems. To find the relationship of the indoor (platform) and outdoor (gate), we analyzed the I/O ratio. The averages of CO and $O_3$ were both higher than one: 1.16 and 1.82, respectively. In the correlations between each material and the others, NO vs $NO_2$ was the highest with R=0.63. In the correlations between indoor and outdoor, $O_3$ was the highest with R=0.64.

• Tunnel and Underground Space
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• v.28 no.1
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• pp.1-24
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• 2018

The use of TBM (tunnel boring machine) gradually increases in worldwide tunneling projects. TBM machine are often applied to more difficult and complex geological conditions in urban area, and many problems and difficulties have been reported due to these geological conditions. However, in Korea, there is a lack of research on difficult grounds so far. This paper discussed general aspects of investigation method, and problems of TBM tunneling in difficult grounds. Construction cases that passed through the difficult grounds in worldwide were analyzed and the typical difficult grounds were classified into 11 cases. For each case, the definition and general problems were summarized. Particularly, for mixed ground and boulder ground, and fault zone, which are frequent geological conditions in urban area with shallow depth, classification system, investigation methods and major considerations were discussed, and proposed the direction of future research. This paper is a basic study for the development of TBM construction technology in difficult ground, and it is expected that it will be useful for related research and construction of TBM in difficult ground in the future.

• Journal of Adhesion and Interface
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• v.5 no.1
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• pp.29-35
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• 2004

We have prepared polyster/nanQhybridized polyimide films in the range of 1~9 wt% of organophilic synthetic layered silicate (STN). Firstly, poly(amic acid)/STN nanocomposite solutions were prepared via solution blending method in DMAc or THF/MeOH solution, and then cast on the polyester film followed by imidization reaction, thermal and chemical method repestively. XRD and TEM experiment showed that the STN was fully exfoliated through the polyimide matrix. Surface morphologies of nanohybridized polyimide films were characterized by AFM and thermal, mechanical properties were also confirmed by TGA, DMA and UTM each. And also, the water vapor permeabilities highly depended on the content of STN. The sample from chemical imidization route and THF/MeOH solvent system showed better water vapor barrier properties than thermal one and DMAc system.

• Journal of the Korean Society for Railway
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• v.14 no.4
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• pp.370-375
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• 2011

In this paper, as a follow-up PRT studies of "J. Lee & K. Kim[2]", in terms of public transportation systems, economic feasibility of PRT systems was investigated. Based on previous studies, PRT demand was estimated and the required number of PRT vehicles has been calculated and the benefit was estimated. To ensure the economic feasibility, construction cost of a PRT system should be the level of 8 billion won per km, and the annual operating costs of the PRT system construction should be approximately 4.63% level. As a result, how much to reduce PRT construction costs, depending on whether decisions are considered to be economically feasible. Thus, PRT technology development will be conducted by targeting the most lightweight and by minimizing the infrastructure and vehicles of PRT.

• Journal of Information Management
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• v.42 no.1
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• pp.221-244
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• 2011

Many records and documents are produced during the process of functions of local councils such as resolution, monitoring and balancing function, representation for the residents, Such records of local councils have importance in terms of objective basis and standards for local policy building and making. The most essential records among these are those of local councils assembly. The fundamental function of local councils is the assembly of individual members of the council and standing committees. For this, the author firstly reviewed the current management system of local council assembly records focusing on Daejeon Yuseonggu Council and conducted researches and interviews with the officers responsible for record keeping. And finally, the author analyzed such researches and findings. From this analysis, the author discovered the problems in the management of record keeping and suggested the improvement for the systematic management firstly in terms of institutional aspects and secondly in terms of the stages of record keeping and management based on ISO 15489, the international standard for information and documentation, records management.