• 디지털산업정보학회논문지
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• 제10권1호
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• pp.113-120
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• 2014

In this paper, I present a new echo canceller using the adaptive cascade system identification (CSI) method, which a system response is divided into several responses so that each response is adaptively estimated and combined. Echo cancellation is required for a dual-duplex DSL, in order to allow each individual loop to operate in a full duplex fashion. Echo cancellation was one of the most difficult aspects of DSL design, requiring high linearity and total echo return loss in excess of 70 dB. Especially, for a fickle response, if the response is estimated by an adaptive filter, the filter needs more taps and the performance is decreased. But the response is divided into several responses, the computation complexities are decreased and the performance is increased. For the stage constant n, which represents the number of stages, if the response is not divided (n=1), the computation complexity of multiply is $2N^2$. And if the response is divided into two responses (n=2), the computation complexity of multiply is $2N^2$. Also, if n=3, the computation complexity is ${\frac{2}{3}}N^2$. Therefore, it is known that the computation complexity is decreased as n is increased. Finally, this proposed method is verified through simulation of echo canceller for digital subscriber line (DSL) application.

• 한국응용과학기술학회지
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• 제21권2호
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• pp.148-155
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• 2004

Response surface analysis was used to study dietary ratios of n-3/n-6 fatty acid and P/S to minimize plasma triglycerides, total cholesterol and LDL ${\cdot}$ VLDL-C levels and maximize plasma HDL ${\cdot}$ C levels of rats. Because the dietary components were not statistically independent, they were studied in combinations of two variables. The two-variable combinations were the most useful in locating the desired maximum or minimum plasma triglycerides, total cholesterol and LDL ${\cdot}$ VLDL-C response in terms of the proportions of the dietary components. Response surface contours and three dimensional plots were developed for each plasma lipid response. The contours and three dimensional plots were used to help determine those combinations of the dietary fatty acid ratios that would produce the desired minimum or maximum lpid responses. The statistical analyses indicated that the minimized plasma cholesterol response levels could be attained with a diet consisting of 2.26 n-3/n-6 fatty acid and 2.15 P/S ratios.

• 한국토양비료학회지
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• 제47권6호
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• pp.594-597
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• 2014

Crop yields depend on the limiting factor of crop growth; Liebig law of minimum. Identifying the kind and the necessary amount of the limiting factor is essential to increase crop yield. Although nitrogen is the most essential nutrient, N application does not always bring about yield increases when other elements are limiting in rice cultivation. Two experiments were compared to elucidate the effect of soil testing on rice yield response to N level. The one was an experiment about yield response of 3 rice cultivars to 7 levels of N application, which was conducted from 2003 to 2004 in 25 farmer's fields without ameliorating soil conditions by soil testing and the other was a demonstration experiment on N fertilizer recommendation equation by 0, 0.5, 1.0, and 1.5 times of N recommended level in 5 soil types from 30 fields after ameliorating soil conditions by soil testing. The N response patterns of the experiments conducted without soil testing showed a Mitscherlich pattern in some cultivars and soil types, but did not in the others. The N response patterns of the demonstration experiment showed a Mitscherlich pattern in all soil types. Because these results indicated that N was the minimum nutrient in the demonstration experiment by ameliorating soil conditions with soil testing, but not in the other experiment without soil testing, the supply of minimum nutrients by soil testing could increase the efficiency of N-fertilization.

• Communications for Statistical Applications and Methods
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• 제31권2호
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• pp.191-202
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• 2024

The goal of this paper is to show how multivariate regression analysis with high-dimensional responses is facilitated by the response dimension reduction. Multivariate regression, characterized by multi-dimensional response variables, is increasingly prevalent across diverse fields such as repeated measures, longitudinal studies, and functional data analysis. One of the key challenges in analyzing such data is managing the response dimensions, which can complicate the analysis due to an exponential increase in the number of parameters. Although response dimension reduction methods are developed, there is no practically useful illustration for various types of data such as so-called large p-small n data. This paper aims to fill this gap by showcasing how response dimension reduction can enhance the analysis of high-dimensional response data, thereby providing significant assistance to statistical practitioners and contributing to advancements in multiple scientific domains.

• 대한약리학회지
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• 제3권1호
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• pp.15-18
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• 1967

Sympathetic ganglionic stimulants (DMPP, Wy-615, TMA and McN-A-343) produced pressor response in chickens anesthetized with phenobarbital sodium. In adrenalectomized chickens the pressor activity of DMPP, Wy -615 and TMA was less than in normal chickens but that of McN-A-343 was unchanged. Hexamethonium (20 mg/kg) and chlorisondamine (5 mg/kg), ganglionic blocking agents, reduced the pressor response to DMPP and Wy-615 but did not abolish the response. The pressor effect of McN-A-343 was not potentiated by the ganglionic flocking agents, but abolished by atropine.

• 한국산업정보학회논문지
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• 제17권3호
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• pp.19-26
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• 2012

RFID 시스템에서 중계 공격에 저항하기 위해 리더와 태그 간의 시도와 응답에 소요된 1비트의 왕복 여행시간 측정을 이용한 거리 한정 프로토콜이 주로 사용된다. 이러한 프로토콜에서 1비트 시도와 응답에 대한 중계 공격의 성공확률을 줄일 수 있으면 효율적인 거리 한정 프로토콜을 만들 수 있다. 본 논문에서는 Hancke와 Khun이 제안한 1비트 시도와 응답 기반의 RFID 거리 한정 프로토콜을 2비트 시도와 응답 기반으로 수정한 효율적인 RFID 거리 한정 프로토콜을 제안한다. n번의 시도와 응답에 대한 중계 공격의 성공확률이 제안된 프로토콜에서는 (7/16)n으로 (3/4)n인 Hancke와 Khun의 프로토콜보다 훨씬 낮다.

• 대한바이러스학회지
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• 제26권1호
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• pp.1-8
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• 1996

Human cytomegalovirus (HCMV) replication and $Ca^{2+}$ response in human cell lines of neuronal origin were investigated. SK-N-SH (neuroblastoma cells) and A172 cells (glioblastoma cells) were used. SK-N-SH cells were permissive for HCMV multiplication with a delay of one day compared to virus multiplication in human embryo lung (HEL) cells. The delay of HCMV multiplication in SK-N-SH cells appeared to be correlated with a delay in the $Ca^{2+}$ response. The cytoplasmic free $Ca^{2+}$ concentration ($[Ca^{2+}]_i$) began to increase at 12 h p.i. in HCMV-infected SK-N-SH cells, while $[Ca^{2+}]_i$ increase in HCMV-infected HEL cells was observed as early as 3 h p.i. On the whole, the level of the increase in $[Ca^{2+}]_i$ in SK-N-SH cells was about 30% of that in HEL cells. On the other hand, in A172 cells infected with HCMV, neither production of infectious virus nor detectable increase in $[Ca^{2+}]_i$ was observed. Treatment with TPA of HCMV-infected SK-N-SH cells resulted in $[Ca^{2+}]_i$ increase at 6 h p.i. The stimulatory effect of TPA on HCMV- induced $[Ca^{2+}]_i$ increase continued until 12 h p.i., but TPA failed to stimulate the $Ca^{2+}$ response in SK-N-SH cells at 24 h p.i., suggesting that the effect of TPA had disappeared in SK-N-SH cells at that time point. In conclusion, SK-N-SH cells are permissive for HCMV replication and the delay in $Ca^{2+}$ response may be a consequence of the lower responsiveness of SK-N-SH cells than HEL cells to HCMV infection.

• Mass Spectrometry Letters
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• 제13권3호
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• pp.84-94
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• 2022

Neoadjuvant chemoradiotherapy (nCRT) is a standard therapy used for locally advanced rectal cancer prior to surgery, which can more effectively reduce the locoregional recurrence rate and radiation toxicity compared to postoperative chemoradiotherapy. The response of patients to nCRT varies, and thus, robust biomarkers for predicting a pathological complete response are necessary. This study aimed to identify possible biomarkers involved in the complete response/non-response of rectal cancer patients to nCRT. Comparative proteomic analysis was performed on rectal tissue samples before and after nCRT. Proteins were extracted for label-free proteomic analysis. Western blot and real-time PCR were performed using rectal cancer cell line SNU-503 and radiation-resistant rectal cancer cell line SNU-503R80Gy. A total of 135 up- and 93 down-regulated proteins were identified in the complete response group. Six possible biomarkers were selected to evaluate the expression of proteins and mRNA in SNU-503 and SNU-503R80Gy cell lines. Lyso-phosphatidylcholine acyltransferase 2, annexin A13, aldo-ketose reductase family 1 member B1, and cathelicidin antimicrobial peptide appeared to be potential biomarkers for predicting a pathological complete response to nCRT. This study identified differentially expressed proteins and some potential biomarkers in the complete response group, which would be further validated in future studies.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2009년도 하계학술대회 논문집
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• pp.224-225
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• 2009

Aluminium nitride thin film was deposited on Au electrode and Si substrate by radio frequency sputtering system. X-ray diffraction (XRD) was utilized to identify the AlN phase, and Atomic Force Microscope (AFM) was used to obtain the images of surface morphology and roughness value of AlN thin film. The result of XRD and AFM measurement showed that the AlN thin film has strong c-axs orientation and smooth surface. In order to investigate piezoelectric response and polarization properties along to the direction of electric field, PFM (Piezoresponse Force Microscope) system was used, and the images of piezoelectric response due to switching of polarization was observed by PFM.

• Asian Pacific Journal of Cancer Prevention
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• 제14권6호
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• pp.3881-3885
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• 2013

Objective: The objective of this study was to identify clinical predictive factors for tumor response after neoadjuvant chemoradiotherapy (nCRT) in locally advanced rectal cancer (LARC). Methods: All factors were evaluated in 88 patients with LARC treated with nCRT. After a long period of 4-8 weeks of chemoradiotherapy, 3 patients achieved clinical complete response (cCR) and thus aggressive surgery was avoided, and the remaining 85 patients underwent a curative-intent operation. The response to nCRT was evaluated by tumor regression grade (TRG) system. Results: There were 32 patients (36.4%) with good tumor regression (TRG 3-4) and 56 (63.6%) with poor tumor regression (TRG 0-2). Lymphocyte counts and ratios were higher in good response cases (P=0.01, 0.03, respectively) while neutrophil ratios and N/L ratios were higher in poor response cases (P=0.04, 0.02, respectively). High lymphocyte ratios before nCRT and good tumor regression (TRG3-4) were significantly associated with improved 5-year disease-free survival (P<0.05). Pretreatment nodal status was also significantly associated with 5-year disease-free survival and 5-year overall survival (P<0.05). Multivariate analysis confirmed that the pretreatment lymphocyte ratio and lymph nodal status were independent prognostic factors. Conclusion: Our study suggested that LARC patients with high lymphocyte ratios before nCRT would have good tumor response and high 5-year DFS and OS.