• 제목/요약/키워드: Multistep

검색결과 140건 처리시간 0.023초

간암의 다단계 발생기전에 관한 연구: 종양형성 과정에서의 생체지표 (Study on mechanism of multistep hepatotumorigenesis in rat : Bio-indices on hepatic tumorigenesis)

  • 강정부;김지경;송승희;하우송
    • 대한수의학회지
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    • 제41권4호
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    • pp.583-589
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    • 2001
  • To estalish bio-indices for detection of the development of multistep hepatotumorigenesis, rats were fed water containing 0.01% diethylnitrosamine (DEN) ad libitum for 13-14 weeks. Hepatocellular carcinoma was developed by treatment with DEN, DEN only was able to induce hepatic tumors in rats without any other cocarcinogen. Compared to control group, liver cytosol protein concentration in all treated grous was significantly decreased (p<0.05). From week to week, $20{\alpha}$-hydroxysteroid dehydrogenase ($20{\alpha}$-HSD) activity was increased and the highest activity was observed on the 12th week (p<0.05). In addition, the urine biopterin concentration was also significantly increased compared to control groups (p<0.05) in a time course manner. These results indicated that $20{\alpha}$-HSD activity, urine biopterin and liver cytosol protein concentration might be very useful maker to hepatic tumorigenesis.

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개량된 초임계수 산화법에 의한 염소계 유기물(PCB, 4-DCBz)의 완전분해반응 (Complete Decomposition of Chlorinated-Organic Compounds(PCB, 4-DCBz) with Improved Supercritical Water Oxidation Method)

  • 이상환;박기철;박윤열;양종규;김정성;부안 박
    • 한국환경과학회지
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    • 제14권5호
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    • pp.513-520
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    • 2005
  • For the destruction of toxic chlorinated organic compounds, this study proposes improved supercritical water oxidation method (multistep oxidation) using sodium nitrate as an oxidizer. This method solves the problems involved in the existing supercritical water oxidation method. Multistep oxidation means that $NaNO_3$ is oxidized to $N_2\;via\;NaNO_2$ and NO. Toxic and hard to destroy organic substances like para-dichlorobenzen(4-DCBz), polychlorinate biphenyl(PCB) ware oxidized to non toxic substances in a condition, in which rapid pressure and temperature rise is restrained as much as possible. 4-dichlorobenzene(4-DCBz) and Polychlorinate biphenyl(PCB) in condition$(450^{\circ}C,\;p_w=0.25g/cm^3,\;30min)$ Was discomposed perfectly.

자동화 비행시험기법에 의한 소형 무인헬리콥터의 파라메터 추정 (Parameter Estimation of a Small-Scale Unmanned Helicopter by Automated Flight Test Method)

  • 방극희;김낙완;홍창호;석진영
    • 제어로봇시스템학회논문지
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    • 제14권9호
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    • pp.916-924
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    • 2008
  • In this paper dynamic modeling parameters were estimated using a frequency domain estimation method. A systematic flight test method was employed using preprogrammed multistep excitation of the swashplate control input. In addition when one axis is excited, the autopilot is engaged in the other axis, thereby obtaining high-quality flight data. A dynamic model was derived for a small scale unmanned helicopter (CNUHELI-020, developed by Chungnam National University) equipped with a Bell-Hiller stabilizer bar. Six degree of freedom equations of motion were derived using the total forces and moments acting on the small scale helicopter. The dynamics of the main rotor is simplified by the first order tip-path plane, and the aerodynamic effects of fuselage, tail rotor, engine, and horizontal/vertical stabilizer were considered. Trim analysis and linearized model were used as a basic model for the parameter estimation. Doublet and multistep inputs are used to excite dynamic motions of the helicopter. The system and input matrices were estimated in the frequency domain using the equation error method in order to match the data of flight test with those of the dynamic modeling. The dynamic modeling and the flight test show similar time responses, which validates the consequence of analytic modeling and the procedures of parameter estimation.

예측 오류 필터를 이용한 블라인드 결정 궤환 등화기 추정 기법 (Blind Direct Decision Feedback Equalization using Prediction Error Filters)

  • 유화선;홍대식
    • 한국통신학회논문지
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    • 제28권3C호
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    • pp.279-285
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    • 2003
  • 본 논문에서는 채널 추정 과정이 필요하지 않은 블라인드 결정 궤환 등화기를 제안하였다. 등화기 계수는 수신신호의 이차 통계 특성을 이용하여 직접 얻어진다. 최적화된 다단계 예측 오류 필터(PEF)의 출력은 채널의 부분응답과 송신 신호열의 곱으로 표현되기 때문에, 역방향 다단계 PEF는 블라인드 결정 궤환 등화기의 피드포워드필터 (FFF)로 사용될 수 있다. 또한 이에 따른 피드백 필터는 심볼율 부분 채널 응답을 통해서 얻어진다. 제안되는 기법은 정확한 채널의 길이를 알지 않아도 안정적인 성능을 가진다는 점에서 기존의 블라인드 채널 추정기법에 비해 장점을 가진다.

MULTI-BLOCK BOUNDARY VALUE METHODS FOR ORDINARY DIFFERENTIAL AND DIFFERENTIAL ALGEBRAIC EQUATIONS

  • OGUNFEYITIMI, S.E.;IKHILE, M.N.O.
    • Journal of the Korean Society for Industrial and Applied Mathematics
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    • 제24권3호
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    • pp.243-291
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    • 2020
  • In this paper, multi-block generalized backward differentiation methods for numerical solutions of ordinary differential and differential algebraic equations are introduced. This class of linear multi-block methods is implemented as multi-block boundary value methods (MB2 VMs). The root distribution of the stability polynomial of the new class of methods are determined using the Wiener-Hopf factorization of a matrix polynomial for the purpose of their correct implementation. Numerical tests, showing the potential of such methods for output of multi-block of solutions of the ordinary differential equations in the new approach are also reported herein. The methods which output multi-block of solutions of the ordinary differential equations on application, are unlike the conventional linear multistep methods which output a solution at a point or the conventional boundary value methods and multi-block methods which output only a block of solutions per step. The MB2 VMs introduced herein is a novel approach at developing very large scale integration methods (VLSIM) in the numerical solution of differential equations.

수치해석 및 계측자료 분석을 통한 막장볼트의 보강효과에 관한 연구 (A comparative analysis of prediction and measurement for reinforcement effect of face bolts)

  • 서경원;김웅구;백기현;김진웅
    • 한국터널지하공간학회 논문집
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    • 제12권5호
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    • pp.359-368
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    • 2010
  • 국내의 경우 터널 지반보강증 강관다단그라우팅 공법이 폭넓게 시용되지만 해외의 경우 시공성 및 경제성이 막장볼트 공법이 흔히 적용되고 있다. 본 논문에서는 국내 도로터널 붕락 발생시 적용한 강관다단그라우팅 및 막장볼트의 적용효과에 대해서 수치해석을 통해 분석해 보았다. 또한 해외 시공사례의 계측데이터를 바탕으로 두 공법의 보강효과에 대해 분석해 보았다. 본 연구를 통해 막장 전면에 파쇄대가 발달하는 경우 페이스공법도 막장보강에 효과적임을 알 수 있었다.

저토피 철도터널구간의 안전 및 시공성을 고려한 개선된 강관다단 그라우팅 공법 적용성 분석 (Applicability Analysis of an Improved Multistep Steel Pipe Grouting Method in Shallow Depth Railway Tunnels in Considering Safety and Constructability)

  • 김낙석;최기성;김석현
    • 대한토목학회논문집
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    • 제40권1호
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    • pp.97-103
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    • 2020
  • 저토피 철도터널구간의 안전 및 시공성을 고려한 굴착보조공법으로서 강관다단 그라우팅 기술이 선정되었다. 특히, 공사 중 과도한 주입압에 의한 지반파괴로 피해가 발생할 우려가 있어 기존 강관다단 그라우팅 공법을 새롭게 개선하여 적용하였다. 본 연구는 00공단에서 발주한 000노반시설 기타공사 구간 중 00안 고속도로 및 00휴게소(하행) 진입로 하부로 통과하는 토피고 11.3~12.1 m 두께의 저토피 철도터널 현장에서 수행하였다. 개선된 강관다단 그라우팅 공법은 새로운 한계주수시험법을 이용한 시공 전 시공조건 평가 기술, 절리의 간격평가, 적합한 주입압력 평가, 최적의 작업완료시간 평가, 주입유형분석에 의한 주입효과평가 기술 등이다. 개선된 강관다단 그라우팅 공법의 적용으로 터널굴착공사 중상부 저토피 구간의 도로를 원활하게 운영할 수 있는 근거를 마련할 수 있었다. 또한, 향후 저토피 구간의 터널강관다단 그라우팅 공사뿐만 아니라 다양한 터널(도로, 지하철, 공동구 등) 강관다단 그라우팅 공사에 적용될 수 있는 가능성을 확인하였다.

A STUDY OF GENERALIZED ADAMS-MOULTON METHOD FOR THE SATELLITE ORBIT DETERMINATION PROBLEM

  • Hong, Bum Il;Hahm, Nahmwoo
    • Korean Journal of Mathematics
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    • 제21권3호
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    • pp.271-283
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    • 2013
  • In this paper, a generalized Adams-Moulton method that is a $m$-step method derived by using the Taylor's series is proposed to solve the satellite orbit determination problem. We show that our proposed method has produced much smaller error than the original Adams-Moulton method. Finally, the accuracy performance is demonstrated in the satellite orbit correction problem by giving a numerical example.

시공단계를 고려할 수 있는 유한요소 해석 모델 개발 (Development of finite element analysis model for multi-step excavation problem)

  • 이연규
    • 터널과지하공간
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    • 제6권4호
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    • pp.326-334
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    • 1996
  • In underground construction the multi-step excavation sequence is commonly adopted for the convenience of the underground work. A numerical simulation method which is capable of analyzing the effects of excavation sequence on the stability of the opening is greatly needed. In this study a two dimensional finite element code was developed based on the effective numerical algorithm for the multistep excavation. The practical applicability of the model was verified for the simplified excavation sequences.

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