• Title/Summary/Keyword: Multiple-trait

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Identification of Promising Bivoltine Breeds based on Multiple Trait Analysis for Future Breeding Program in West Bengal, India

  • Chanda, Subhra;Saha, Lal Mohan;Das, Nirvan Kumar;Kar, Niharendu Bikash;Bindroo, Bharat Bhusan
    • International Journal of Industrial Entomology and Biomaterials
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    • v.23 no.2
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    • pp.239-243
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    • 2011
  • Thirty five bivoltine breeds were acclimatized under controlled condition for three years during two seasons to evaluate their efficiency in Seri industry of tropical region. Out of thirty five ten breeds had been short listed based on ranking for individual trait. Three breeds out of those ten selected breeds viz. SK6, NB18 and B.Con.4 ranked top in respect of overall performance. The ten breeds based on average Evaluation Index value > 50 considering twelve economically important traits are the resource material for future course of breeding program in West Bengal.

Genetic Architecture of Transcription and Chromatin Regulation

  • Kim, Kwoneel;Bang, Hyoeun;Lee, Kibaick;Choi, Jung Kyoon
    • Genomics & Informatics
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    • v.13 no.2
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    • pp.40-44
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    • 2015
  • DNA microarray and next-generation sequencing provide data that can be used for the genetic analysis of multiple quantitative traits such as gene expression levels, transcription factor binding profiles, and epigenetic signatures. In particular, chromatin opening is tightly coupled with gene transcription. To understand how these two processes are genetically regulated and associated with each other, we examined the changes of chromatin accessibility and gene expression in response to genetic variation by means of quantitative trait loci mapping. Regulatory patterns commonly observed in yeast and human across different technical platforms and experimental designs suggest a higher genetic complexity of transcription regulation in contrast to a more robust genetic architecture of chromatin regulation.

Modifications of heterobeltiosis, heterosis, and hybrid vigour over check parent formulae to enhance judgment on hybrids

  • Ghazy, Usama M.;Fouad, Tahia A.
    • International Journal of Industrial Entomology and Biomaterials
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    • v.42 no.2
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    • pp.33-45
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    • 2021
  • Many researchers are using the heterosis, heterobeltiosis and hybrid vigour over check parent value formulae to determine the hybrid vigour for animals, plants and silkworm breeding. These formulae are ideal for determine the hybrid vigour for the positive direction of single trait. It is difficult using these formulae for multiple traits. Suggested modification for cardinal formulae were made as well as suggestion new formula for determines hybrid vigour for multiple traits. Modifications of hybrid vigour were made to facilitate judgment of best hybrids under study for multiple traits. Nineteen local hybrids of mulberry silkworm were prepared for these investigations in addition the imported Bulgarian hybrid. Comparison between the cardinal and the modifications formulae were applied for thirteen economic characters. Nine positive and four negative direction characters were observed. Modified formulae make the judgment of heterobeltiosis, heterosis and hybrid vigour over check parent value very facilitate for positive and negative traits.

Trait Anxiety as a Mediator of the Association between Attention Deficit Hyperactivity Disorder Symptom Severity and Functional Impairment

  • Oh, Yunhye;Yoon, Hee Joon;Kim, Ji-Hae;Joung, Yoo Sook
    • Clinical Psychopharmacology and Neuroscience
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    • v.16 no.4
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    • pp.407-414
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    • 2018
  • Objective: Anxiety has been shown to influence functional impairment in patients with attention deficit hyperactivity disorder (ADHD). This study aimed to compare functional impairment in subjects with and without adult ADHD and to investigate the associations among trait anxiety, functional impairment, and ADHD symptom severity. Moreover, the effects of ADHD symptom subtypes on trait anxiety and functional impairment were also examined. Methods: The sample included 209 adults between the ages of 20 and 31 years. Fifty-one adults received a diagnosis of ADHD, and an additional age, sex-matched group of 51 adults comprised the adult control. Participants were assessed with Conners' Adult ADHD Rating Scales (CAARS), the Beck Depression Inventory (BDI), the Spielberg Trait Anxiety Inventory (STAI-T), and the Sheehan Disability Scale (SDS). The relationships among ADHD severity, anxiety, and functional impairment were investigated using Pearson's correlation analysis. Subtypes of ADHD symptoms that predicted anxiety and functional impairment were investigated using regression analyses. Results: Adult ADHD patients significantly differed from normal control subjects according to BDI, STAI-T, and SDS assessment. Significant positive correlations were noted between ADHD severity, anxiety, and functional impairment. Multiple linear regression analysis confirmed anxiety as a mediator between functional impairment and ADHD CAARS symptom subscales. Conclusion: Patients with adult ADHD showed higher levels of anxiety, depression, and functional impairment. Additionally, ADHD symptoms and anxiety impacted subject functional impairment. Our results suggest that anxiety may be a strong mediator between ADHD severity and functional impairment.

Psychosocial Factors Influencing Anxiety Symptoms in Patients With Hypertension (고혈압 환자에서 불안증상에 영향을 미치는 정신심리학적 요인)

  • Moon, Seock Hyeon;Kim, Seung-Gon;Yang, Hae-Jung;Seo, Eun Hyun;Yoon, Hyung-Jun
    • Anxiety and mood
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    • v.18 no.1
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    • pp.17-25
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    • 2022
  • Objective : The aim of this study was to investigate the prevalence of anxiety symptoms and its association with psychological factors in patients with hypertension. Methods : The Participants included 124 patients with hypertension. Anxiety symptoms were evaluated by the Hospital Anxiety and Depression Scale. Socio-demographics, perceived stress, state-trait anger, life satisfaction, and ego resiliency were assessed. Stepwise multiple regression analyses were carried out to examine the impact of perceived stress, state-trait anger, and life satisfaction on anxiety symptoms. In addition, moderated regression analysis was performed to explore the moderating effect of ego resiliency between perceived stress and anxiety symptoms. Results : A total of 17 subjects (13.7%) were identified as having anxiety symptoms. Higher perceived stress and state-trait anger, and lower life satisfaction were found to be significant correlates of anxiety symptoms. In the final model, higher levels of perceived stress (β=0.378, p<0.001) and trait anger (β=0.320, p<0.001) were related to higher levels of anxiety symptoms, while a higher level of life satisfaction (β=-0.166, p=0.025) was associated with a lower level of anxiety symptoms. Further, ego resiliency buffered the negative effect of perceived stress on anxiety symptoms. Conclusion : This study demonstrated the prevalence of anxiety symptoms and associated psychological factors among patients with hypertension. Our findings suggest that improving life satisfaction and ego-resiliency as well as controlling stress and anger may be important in the management of anxiety symptoms in patients with hypertension.

Genetic parameter analysis of reproductive traits in Large White pigs

  • Yu, Guanghui;Wang, Chuduan;Wang, Yuan
    • Animal Bioscience
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    • v.35 no.11
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    • pp.1649-1655
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    • 2022
  • Objective: The primary objective of this study was to determine the genetic parameters for reproductive traits among Large White pigs, including the following traits: total number born (TNB), number born alive (NBA), litter birth weight (LBW), average birth weight (ABW), gestation length (GL), age at first service (AFS) and age at first farrowing (AFF). Methods: The dataset consisted of 19,036 reproductive records from 4,986 sows, and a multi-trait animal model was used to estimate genetic variance components of seven reproductive traits. Results: The heritability estimates for these reproductive traits ranged from 0.09 to 0.26, with the highest heritability for GL and AFF, and the lowest heritability for NBA. The repeatabilities for TNB, NBA, LWB, ABW, and GL were ranged from 0.16 to 0.34. Genetic and phenotypic correlations ranged from -0.41 to 0.99, and -0.34 to 0.98, respectively. In particular, the correlations between TNB, NBA and LBW, between AFS and AFF, exhibited a strong positive correlation. Furthermore, for TNB, NBA, LBW, ABW, and GL, genetic correlations of the same trait between different parities were moderately to strongly correlated (0.32 to 0.97), and the correlations of adjacent parities were higher than those of nonadjacent parities. Conclusion: All the results in the present study can be used as a basis for the genetic assessment of the target population. In the formulation of dam line selection index, AFS or AFF can be considered to combine with TNB in a multiple trait swine breeding value estimation system. Moreover, breeders are encouraged to increase the proportion of sows at parity 3-5 and reinforce the management of sows at parity 1 and parity ≥8.

The Effect of Empowering Leadership on Adaptive Performance: The Mediating Effect of Job Challenge and the Moderating Effect of Agentic and Communal Traits (임파워링 리더십이 적응수행에 미치는 영향: 직무도전성의 매개 효과와 독자성·융화성 성향의 조절효과)

  • Sun-Hwa Jung;Eun-Ji Park;He-Yeon Kim;Ji-Hwan Park
    • Asia-Pacific Journal of Business
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    • v.14 no.3
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    • pp.67-88
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    • 2023
  • Purpose - This study examined the effect of empowering leadership on adaptive performance and verified the mediating effect of job challenge in the relationship between empowering leadership and adaptive performance. Additionally, this study investigated the moderating effect of agentic and communal traits in the relationship between supervisor's empowering leadership and adaptive performance of subordinates. Design/methodology/approach - This study used data collected from 279 participants via an online platform. Multiple regression analysis, bootstrapping, hierarchical regression analysis, and simple slope test were used to analyze the data. Findings - First, supervisor's empowering leadership had a positive effect on adaptive performance. Second, job challenge was found to mediate the relationship between supervisor's empowering leadership and adaptive performance. Third, the agentic trait showed a moderating effect on strengthening the relationship between supervisor's empowering leadership and adaptive performance. However, communal trait did not show a moderating effect. Research implications or Originality - This study examined the moderating effect of agentic traits in the relationship between empowering leadership and adaptive performance, which has not been investigated before.

Genetic Relationship between Carcass Traits and Carcass Price of Korean Cattle

  • Kim, Jong-Bok;Kim, Dae-Jung;Lee, Jeong-Koo;Lee, Chae-Young
    • Asian-Australasian Journal of Animal Sciences
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    • v.23 no.7
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    • pp.848-854
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    • 2010
  • The objectives of this study were to estimate genetic parameters for the carcass price and carcass traits contributing to carcass grading and to investigate the influence of each carcass trait on the carcass price using multiple regression and path analyses. Data for carcass traits and carcass prices were collected from March 2003 to January 2009 on steers of Korean cattle raised at private farms. The analytical mixed animal model, including slaughter house-year-month combination, linear and quadratic slaughter age as fixed effects and random animal and residual effects, was used to estimate genetic parameters. The effects of carcass traits on the carcass price were evaluated by applying multiple regression analyses. Heritability estimates of carcass traits were $0.20{\pm}0.08$ for carcass weight (CWT), $0.33{\pm}0.10$ for back fat thickness (BFT), $0.07{\pm}0.05$ for eye-muscle area (EMA) and $0.25{\pm}0.10$ for marbling score (MS), and those of carcass prices were $0.21{\pm}0.10$ for auction price per 1 kg of carcass weight (AP) and $0.13{\pm}0.07$ for total price (CP). Genetic correlation coefficients of AP with CWT and MS were $-0.35{\pm}0.29$ and $0.99{\pm}0.04$, respectively, and those of CP with CWT and MS were $0.59{\pm}0.22$ and $0.39{\pm}0.29$ respectively. If an appropriate adjustment for temporal economic value is available, the moderate heritability estimates of AP and CP might suggest their potential use as the breeding objectives for improving the gross incomes of beef cattle farms. The large genetic correlation estimates of carcass price variables with CWT and MS implied that simultaneous selection for both CWT and MS would be also useful in enhancing income.

MULTIPLE ODONTOGENIC KERATOCYST OF MANDIBLE WITH FAMILIAL TRAIT (가족력을 동반한 다발성 치성각화낭종)

  • Kim, Jong-Won;Kim, Yu-Jin;Pyun, Yung-Nam;Kim, Jong-Chull;Kim, Myung-Jin;Lee, Jong-Ho;Myoung, Hoon
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.21 no.1
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    • pp.74-80
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    • 1999
  • A family is presented in which multiple odontogenic keratocysts have been expressed. 3 members of the two generations of family with features of multiple keratocysts, suspected basal cell nevus syndrome have been investigated. The proband, 19-year-old woman and her mother, and her brother suffered from these cysts and two female patients' disease have been recurred multiply though careful treatments. Close attention to the family and routine follow up will alert the clinician to its recurrences and genetic counseling and serial screening for the development of other symptoms, that is malignant skin carcinoma etc.

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Estimation of Genetic Parameter for Growth Traits of Olive Flounder Paralichthys olivaceus on the 8th Generation of Selective Breeding Using Multiple Traits Animal Model (다형질 Animal Model을 이용한 선발 8세대 육종 넙치(Paralichthys olivaceus)의 성장형질에 대한 유전모수 추정)

  • Park, Jong-Won;Lee, Dain;Jung, Hyo Sun;Kim, Julan;Yang, Hye-Rim;Kim, Hyun-Chul;Lee, Jeong-Ho
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.55 no.5
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    • pp.549-556
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    • 2022
  • The aim of this study was to evaluate the genetic parameters of growth traits for improvement breeding in olive flounder Paralichthys olivaceus at the 8th generation of selective breeding in April 2021. Growth traits such as total length, body weight and condition factor at 11 months of age were measured for 7,508 individuals with confirmed paternity. Data were analyzed using the restricted maximum likelihood method applied to a multiple traits animal model. The effects of sex and family were significantly different across traits (P<0.05). The heritability values of total length, body weight and condition factor were estimated to be high as 0.479, 0.457, and 0.466, respectively. Correlation analysis between phenotypic and breeding values, indicated that the selection accuracy was 75.9-85.2% for all traits. To increase the selection accuracy for parent fish selection, the sex and pedigree characteristics that affect each trait should be considered. Moreover, further improvement of multiple traits can be achieved if the correlation between each trait is appropriately considered.