• Korean Journal of Veterinary Research
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• v.60 no.1
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• pp.25-32
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• 2020

Natural killer (NK) cells play have a crucial role in the early phase of immune responses against various pathogens. We compared characteristics of canine NK cells against two canine mammary carcinoma cell lines, REM134 and CF41.Mg. REM134 showed higher expression of progesterone receptor, proliferative cell nuclear antigen, Ki67, multiple drug resistance, Bmi-1, c-myc, E-cadherin, and human epidermal growth factor receptor type-2 than that of CF41.Mg. For specific expansion and activation of NK cells, we isolated CD5 negative cells from canine peripheral blood mononuclear cells and co-cultured K562 cells in the presence of interleukin (IL)-2, IL-15, and IL-21 for 21 days. As a result, we found that expression markers of activated NK cells such as NKp30, NKp44, NKp46, NKG2D, CD244, perforin, granzyme B, and tumor necrosis factor alpha were highly upregulated. In addition, we found there was upregulated production of interferon gamma of activated NK cells against target cells such as REM134 and CF41.Mg. Specifically, we observed that cytotoxicity of NK cells against target cells was more sensitively reacted to CF41.Mg than REM134. Based on the results of this study, we recommend the development of an experimental application of CF41Mg, which has not been reported in canine mammary carcinoma research.

• Communications of Mathematical Education
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• v.31 no.1
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• pp.49-70
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• 2017

The purpose of this study was to investigate the relative influence of multiple error sources and to find optimal measurement conditions that obtain a desired level of reliability of a creative attitude test in mathematical creativity. This study analyzed the scores of the Creative Attitude Scale-Korea allowed to access publicly of 125 general students and 109 mathematically gifted students by performing a multivariate generalizability analysis. The main results were as follows. First, based on reliability, the Creative Attitude Scale-Korea was measured less precisely for mathematically gifted students. On the contrary, based on the conditional standard error of measurement, it was measured less precisely for general students. However, the Creative Attitude Scale-Korea showed strong reliability in both groups. Second, the optimal weights should adjust to .3, .3, .4 in mathematically gifted students and .4, .4, .2 in general students with three scoring components of divergent attitude, problem solving attitude, and convergent attitude based on the maximum reliability. Third, to approach desirable reliability, it is possible to use one component of divergent attitude in general students but three components of divergent attitude, problem solving attitude, and convergent attitude in mathematically gifted students. Finally this study proposed application plans for the Creative Attitude Scale-Korea and future directions of research.

• Journal of Food Hygiene and Safety
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• v.33 no.2
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• pp.118-123
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• 2018

The objective of this study was to develop a sensitive method for the identification and determination of nitrovin in fishery products by using a solid-phase extraction (SPE), as performed with a liquid chromatography-tandem mass spectrometry (LC-MS/MS). The samples were extracted with a mixture of acetonitrile and water, and were then defatted with acetonitrile saturated hexane, after which further clean-up was accomplished with SPE on the hydrophilic-lipophilic balance (HLB) cartridges. The analytes were subsequently ionized in the positive mode of an electrospray ionization (ESI), and where thereby detected in a process of multiple reaction monitoring (MRM). The linearity (expressed as correlation coefficients) of the matrix calibration curves was > 0.985. The limit of the quantification for the nitrovin was measured at 0.001 mg/kg. The accuracy (expressed as average recovery) was noted between 72.1 and 122%. The precision (expressed as coefficient variation) was noted from 2.9 to 16.9%. According to the CODEX CAC/GL-71 guideline accuracy, precision, linearity, and limit of detection were determined in three matrices (which were flatfish, eel and shrimp). The proposed method was suitable for analyzing the associated nitrovin residues. This application and result can also be a factor to contribute to the non-detection drugs management in fishery products.

• Journal of Korean Society of Forest Science
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• v.90 no.1
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• pp.133-138
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• 2001

Increased base cation loss and Al mobilization, a consequence of soil acid neutralization responses, are common in air polluted areas showing forest decline. The prediction models of acid neutralization responses were developed by using indicators of soil acidification level(pH, and base saturation) in order to assess the forest soil sensitivity to acidification. The soil acidification level was greatest in Namsan followed by Kanghwa, Ulsan, and Hongcheon, being contrary to regional total $ANC_H$ pattern through soil columns leached with additional acid ($16.7mmol_c\;H^+/kg$), Both base exchange and Al dissolution were main acid neutralization processes in all study regions. There were low base exchange and high Al dissolution in the regions of the low total $ANC_H$. The $ANC_M$ by sulfate adsorption was greatest in Hongcheon compared with other regions even though the AN rate was very low as 6.4%. Coefficients of adjusted determination of simple and multiple regression models between soil acidification level indicators and the acid neutralization responses were more than 0.52(p<0.04) and 0.89(p<0.01), respectively. The result suggests that soil pH and base saturation are available indicators for predicting the acid neutralization responses. These prediction models could be used as an useful method to measure forest soil sensitivity to acidification.

• Journal of Korea Water Resources Association
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• v.44 no.12
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• pp.1015-1029
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• 2011

Conventional MCDA techniques have been used in the field of water resources in the past. A GIS can offer an effective spatial data-handling tool that can enhance water resources modeling through interfaces with sophisticated models. However, GIS systems have a limited capability as far as the analysis of the value structure is concerned. The MCDA techniques provide the tools for aggregating the geographical data and the decision maker's preferences into a one-dimensional value for analyzing alternative decisions. In other words, the MCDA allows multiple criteria to be used in deciding upon the best alternatives. The combination of GIS and MCDA capabilities is of critical importance in spatial multi-criteria analysis. The advantage of having spatial data is that it allows the consideration of the unique characteristics at every point. The purpose of this study is to identify, review, and evaluate the performance of a number of conventional MCDA techniques for integration with GIS. Even though there are a number of techniques which have been applied in many fields, this study will only consider the techniques that have been applied in floodplain decision-making problems. Two different methods for multi-criteria evaluation were selected to be integrated with GIS. These two algorithms are Compromise Programming (CP), Spatial Compromise Programming (SCP). The target region for a demonstration application of the methodology was the Suyoung River Basin in Korea.

• Journal of Radiation Industry
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• v.4 no.3
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• pp.221-226
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• 2010

Physical detection methods, photostimulated luminescence (PSL), thermoluminescence (TL) and electron spin resonance (ESR) were applied to detect electron beam-irradiated agricultural products, such as red pepper, black pepper, raisin, walnut, beef seasoning and pistachio. The absorbed irradiation doses for representative samples were controled at 0, 1, 3, 5 and 10 kGy. PSL values for non-irradiated samples were <700 counts/60s (lower threshold, $T_1$) except beef seasoning, whereas those of irradiated samples were more than 5,000 photon counts, upper threshold ($T_2$) in black pepper, raisin, and beef seasoning and intermediates values of $T_1-T_2$ in red pepper, walnut, and pistachio. Minerals seperated from the samples for TL measurement showed that non-irradiated samples except pistachio (TL ratio, 0.12) were characterized by no glow curves situated at temperature range of $50{\sim}400^{\circ}C$ with TL ratio (0.01~0.08), while irradiated samples except pistachio at only 1 kGy (TL ratio, 0.08) indicated glow curve at about $150{\sim}250^{\circ}C$ with TL ratio (0.28~3.10). ESR measurements of irradiated samples showed any specific signals to irradiation. The samples of both red pepper and pistachio were produced specific signals derived from cellulose radicals as well as single line signals for black pepper and walnut, and multiple signals derived from crystalline sugar radicals for raisin and beef seasoning. In conclusion, The ESR methods can apply for detection of pistachio exposed to electron beam but PSL and TL are not suitable methods. Furthermore, TL and ESR suggeted that both techniques were more useful detection method than PSL to confirm whether red pepper, walnut and beef seasoning samples have been exposed to electron beam.

• Korean Journal of Remote Sensing
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• v.11 no.3
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• pp.49-60
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• 1995

Features of geological lineaments generally play an important role at the data interpretation concerned geological processes, mineral exploration or natural hazard risk estimation. However, there are intrinsically discordances between lineaments-related features extracted from surficial geological syrvey and those from satellite imagery;nevertheless, any data set contained those information should not be considred as less meaningful within their own task. For the purpose of effective utilization task of extracted lineaments, the mathematical scheme, based on fuzzy set theory, for practical integration of various types of rasterized data sets is studied. As a real application, the geological map named Homyeong sheet(1:50,000) and the Landset TM imageries covering same area were used, and then lineaments-related data sets such as lineaments on the geological map, lineaments extracted from a false-color image composite satellite, and major drainage pattern were utilized. For data fusion process, fuzzy membership functions of pixel values in each data set were experimentally assigned by percentile, and then fuzzy algebraic sum operator was tested. As a result, integrated lineaments by this well-known operator are regarded as newly-generated reasonable ones. Conclusively, it was thought that the implementation within available GISs, or the stand-alone module for general applications of this simple scheme can be utilized as an effective scheme can be utilized as an effective scheme for further studies for spatial integration task for providing decision-supporting information, or as a kind of spatial reasoning scheme.

• Journal of the Korean Society for Railway
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• v.16 no.3
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• pp.207-216
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• 2013

The components of concrete track (rail and rail fastening system) in railway bridge deck ends are damaged and deteriorated by track-bridge interaction forces such as uplift forces and compression forces owing to their structural flexural characteristics (bridge end rotation). This had led to demand for alternatives to improve structural safety and serviceability. In this study, the authors aim to develop a transition track to enhance the long term workability and durability of concrete track components in railway bridge deck ends and thereby improve the performance of concrete track. A time-history analysis and a three-dimensional finite element method analysis were performed to consider the train speed and the effect of multiple train loads and the results were compared with the performance requirements and German standard for transition track. Furthermore, two specimens, a normal concrete track and a transition track, were fabricated to evaluate the effects of application of the developed transition track, and static tests were conducted. From the results, the track-bridge interaction force acting on the track components (rail displacement, rail stress, and clip stress) of the railway bridge deck end were significantly reduced with use of the developed transition track compared with the non-transition track specimen.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.20 no.5
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• pp.35-44
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• 2021

In recent times, several studies have been conducted focusing on crashes occurring on the main segment of the highway. However, there is a dearth of research dealing with traffic safety relating to other highway facilities, especially ramp areas. According to the Korea Expressway Corporation's Expressway Information Service, 6,717 crashes have occurred on ramps in the five years from 2015~2019, which accounts for about 15% of all highway accidents. In this study, the simple and full safety performance functions (SPFs) were evaluated and explored using different statistical distributions (i.e., Poisson Gamma (PG) and Poisson Inverse Gaussian (PIG)) and techniques (i.e., fixed effects (FE) and random effects (RE)) to provide more accurate crash prediction models for highway ramp sections. Data on the geometric characteristics of traffic and roadways were collected from various systems and with extensive efforts using a street-view application. The results showed that the PIG models present more accurate crash predictions in general. The results also indicated that the RE models performed better than FE models for simple and full SPFs. The findings from this study offer transportation practitioners using the Korea Expressway Corporation's Expressway a dependable reference to enhance and understand traffic safety in ramp areas based on accurate crash prediction models and empirical evidence.

• The Journal of the Convergence on Culture Technology
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• v.7 no.2
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• pp.325-331
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• 2021

The purpose of this study was to identify the effect of dementia attitudes according to dementia education in university students on the recognition of dementia policy, focusing on the mediating effect of dementia knowledge. The participants were 306, 1~2 grad of students of U and K university in 2 G cities. The data were collected from September 1 to 31, 2017, and analyzed using the SPSS/WIN 21.0 program with t-test, Pearson correlation coefficients and multiple stepwise regression. There were significant differences in the education group compared to the non-education group in recognition of dementia policy, dementia knowledge, and dementia attitude according to the subject's dementia education. The level of dementia attitudes, recognition of dementia policy, dementia knowledge and attitudes were more than moderate. The positive correlations among recognition of dementia policy, dementia knowledge and attitudes were significant. Dementia knowledge was a predictor of recognition of dementia policy (t=2.35, p=019) and showed a significant partial mediating effect, and the explanatory power was 17.8%. It is necessary to continuously systematically provide the development and application of dementia education programs for the whole people to raise correct dementia knowledge, positive attitudes toward dementia, and awareness of dementia policies.