• Journal of Korean Neurosurgical Society
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• v.30 no.12
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• pp.1435-1438
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• 2001

A case of nonsecretory multiple myeloma in a 66 year-old-woman is reported. At first, she complained severe neck pain and radiologic finding showed C2 pathologic fracture. She complained severe low back pain 4 month later and L1 compression fracture was found. The lumbar MRI showed a 1.4cm-sized round enhancing lesion in the body of T12. Bone marrow aspiration biopsy at L1 spine showed a few polymorphous and small nests of mononuclear cell. L1 lamina bone biopsy showed many abnormal plasma cells. Pathologic diagnosis was multiple myeloma. However, plasma electrophoresis and protein immunoelectrophoresis of serum and urine of patient were normal. So, it is a nonecretory multiple myeloma case and the incidence of nonsecretory multiple myeloma is known to about 1% of all multiple myeloma.

• Journal of ILASS-Korea
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• v.18 no.4
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• pp.176-181
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• 2013

In this study, injection quantity, rate and spray image of multiple injections which are important design parameters for a piezo type injector have been investigated. Interval of injections and a number of injections in multiple injection strategy has been controlled to verify interaction of each injection. Spray characteristics of multiple injections have been researched through optical process with a high speed camera in a high pressure chamber. In addition, a method of RMS(Root Mean Square) process has been used for comprehending the distribution of injection easily. As a result, in case of piezo type injector, characteristics of injection quantity according to charging voltage and the difference of injection quantity between single and triple injection were confirmed. Also, injection rate for increasing injection duration was confirmed. And spray characteristics of multiple injections were improved; multiple injections were possible in a shorter time interval between each injection. With this study, a possibilities of more accurate multiple injection control would be expected.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.41 no.10
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• pp.61-67
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• 2004

The next generation cellular wireless communication systems require high data rate transmissions and large system capacities. In order to meet these requirements, multiple antennas can be used at the base and mobile stations, forming MIMO(Multiple Input Multiple Output) channels. This paper proposes a MIMO SDMA(Space Division Multiple Access) technique with dynamic slot allocation which allows the transmitter to efficiently transmit parallel data streams to each of multiple receivers. The proposed technique can increase system capacities significantly by transmitting a larger number of data streams than conventional MIMO techniques while minimizing the performance degradation due to the beamforming dimension reduction.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.8
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• pp.3163-3166
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• 2015

Background: Patients with refractory or relapsed multiple myeloma are considered to have a very poor prognosis, and new regimens are needed to improve this setting. Pomalidomide is a new immunomodulatory drug with high in vitro potency. Immunomodulatory drugs are hypothesized to act through multiple mechanisms. Here we performed a systemic analysis to evaluate pomalidomide-based chemotherapy (pomalidomide in combination with low-dose dexamethasone) as salvage treatment for patients with refractory and relapsed multiple myeloma. Methods: Clinical studies evaluating the efffectiveness of pomalidomide based regimens on response and safety for patients with refractory and relapsed multiple myeloma were identified using a predefined search strategy. Pooled response rate (RR) of treatment were calculated. Results: For pomalidomide based regimens, 4 clinical studies which including 291 patients with refractory and relapsed multiple myeloma were considered eligible for inclusion. Systemic analysis suggested that, in all patients, pooled RR was 41.2% (120/291). Major adverse effects were hematologic toxicity, including grade 1 or 2 anemia, leucopenia and thrombocytopenia with pomalidomide based treatment. No treatment related death occurred. Conclusion: This pooled analysis suggests that pomalidomide in combination with low-dose dexamethasone is active with good tolerability in treating patients with refractory or relapsed multiple myeloma.

• Journal of Advanced Navigation Technology
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• v.16 no.1
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• pp.62-69
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• 2012

Multiple-control Toffoli(MCT) gates are macro-level multiple-valued gates needing quantum technology dependent primitive gates, and have been used in Galois Field sum-of-product (GFSOP) based synthesis of quantum logic circuit. Reversible logic is very important in quantum computing for low-power circuit design. This paper presents a reversible GF4 multiplier at first, and GF4 multiplier based quaternary MCT gate realization is also proposed. In the comparisons of MCT gate realization, we show the proposed MCT gate can reduce considerably primitive gates and delays in contrast to the composite one of the smaller MCT gates in proportion to the multiple-control input increase.

• Archives of Plastic Surgery
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• v.36 no.4
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• pp.493-496
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• 2009

Purpose: Glomus tumors are neoplasms that are composed of modified smooth muscle cells of the glomus body and multiple glomus tumor comprises 10% of all glomus tumors. We report a case of disseminated multiple glomus tumors. Methods: A 14 - year - old boy presented with multiple subcutaneous purple nodules on the right cheek, back, right arm, right hand dorsum, right fourth finger, and left ankle. Nodules on the back and right fourth finger were completely excised under local anesthesia and histopathologic examination was followed. Results: Histopathologic findings showed numerous dilated, cavernous - like, thin - walled, vascular spaces surrounded by one or a few layers of glomus cells. On immunohistochemical examination, glomus cells stain for smooth muscle actin, and endothelial cells stain for CD31. Those revealed multiple glomangiomas. Conclusion: A review of Korean literature revealed only one reported cases of disseminated multiple glomus tumors, so this is the second case to be reported in the Korean literature. In case of multiple soft tissue tumors, thorough physical examination and preoperative evaluation is needed.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2006.05a
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• pp.133-137
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• 2006

In general, a measuring instrument of sound noise use only one wired channel by one sensor. Therefor the measuring instrument use wired cables as the number of channels are provided by instrument. In a point of observed target it needs data from multiple sensors and In case of measured point is a large numbers the environment of constitution would be complicated because that is in need of channel and cable. So we need the method that can improve the existing transmission channel and cable environment even the measured point is increased. If we use the Code Division Multiple Access(CDMA) we transmit a large numbers of sensor data by using a common transmission channel. We present the method that transmits data of multiple sensor to wireless by using CDMA. This method can simplify the measurement environment dramatically when collecting data by using multiple sensor. We expect this study to contribute the part of multiple access technology and relation technologies on the measuring environment.

• Journal of Institute of Control, Robotics and Systems
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• v.16 no.3
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• pp.293-299
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• 2010

The multiple block localization method in a wide area for multiple robots using iGS is proposed in this paper. The iGS is developed for the indoor global localization using ultrasonic and RF sensors. To measure the distance between a mobile robot and a beacon, the tag on the mobile robot wakes up one beacon to send out the ultrasonic signal and measures the traveling time from the beacon to the mobile robot. As the number of robots is increased, the sampling time of localization also becomes longer. Note that only one robot can localize its own position calling beacons one by one during each of the sampling interval. This is a severe constraint for the localization of multiple robots in a wide area. This paper proposes an efficient localization algorithm for the multiple robots in a wide area which can be divided into multiple blocks. For a given block, a master beacon is designated to synchronize robots. By the access of the synchronization signal, each beacon in the selected group sends out an ultrasonic signal. When the robots in the block receive the ultrasonic signal, they can calculate their own locations based on the distances to the beacons, which are obtained by the multiplication of flight time and velocity of the ultrasonic signal. The efficiency of the algorithm is verified through the real experiments.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.29 no.12
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• pp.47-54
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• 2015

Normally, multiple socket-outlet is manufactured with soldered, welded permanent connection (termination). Because this procedure is very non-environmental and requires many labor forces, many companies skip this process. To solve this these problems, this research had to design permanent joint type multiple socket-outlet, develop safer multiple socket-outlet than is sold in markets. Progressing this research, we took 3 steps. First, we had to design device for fixing a frame suitable for multiple socket-outlet. Second, this multiple socket-outlet must pass fundamental standards through international standard (IEC 60884-1) and Korean standard (K 60884-1) tests. Third, it had to pass both several mechanical and electrical tests which is more strict than fundamental standards and vibration and impact tests following KS standards for enhancing its safety. After finishing 3 steps, we could obtain objective and fair data, develop environmental permanent joint type multiple socket-outlet without soldering crimped connection.

• Tuberculosis and Respiratory Diseases
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• v.69 no.2
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• pp.129-133
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• 2010

Extramedullary plasmacytoma (EMP) is a rare disorder that typically occurs in the upper airway. Although the condition rarely arises in the lungs, a few cases have been reported. Here, we report a case of pulmonary plasmacytoma in 66-year-old man, who had been treated with VAD (vincrestine, adriamycin, dexamethasone) chemotherapy for multiple myeloma. The patient had been declared clear of multiple myeloma after 4 cycles of chemotherapy. Three months later, the patient had multiple masses visible on computed tomography (CT) and on positron emission tomography-computed tomography (PET-CT) with hot uptake. Subsequent studies using CT-guided needle biopsy and immunohistochemical stain showed pulmonary plasmacytoma. Bone marrow biopsy, serum, and urine M protein tests were repeated, showing no evidence of multiple myeloma. Pulmonary plasmacytomas, as extramedullary plasmacytomas, were considered an isolated manifestation of multiple myeloma recurrence. We treated the patient with concurrent chemoradiotherapy and the pulmonary plasmacytomas regressed dramatically.